product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
iNOS Antibody - BSA Free
catalog :
NB300-605
quantity :
200 uL (also 0.04 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 113
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:400; loading ...; fig 2e
Larue M, Parker S, Puccini J, Cammer M, Kimmelman A, Bar Sagi D. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer. Proc Natl Acad Sci U S A. 2022;119:e2119168119 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 6k
Theruvath J, Ménard M, Smith B, Linde M, Coles G, Dalton G, et al. Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. Nat Med. 2022;28:333-344 pubmed publisher
  • immunohistochemistry; human; 1:250; loading ...; fig 7a
Gredic M, Wu C, Hadžić S, Pak O, Savai R, Kojonazarov B, et al. Myeloid cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice. Eur Respir J. 2021;: pubmed publisher
  • western blot; human; 1:200; loading ...; fig 6g
Li H, Liao Y, Gao L, Zhuang T, Huang Z, Zhu H, et al. Coronary Serum Exosomes Derived from Patients with Myocardial Ischemia Regulate Angiogenesis through the miR-939-mediated Nitric Oxide Signaling Pathway. Theranostics. 2018;8:2079-2093 pubmed publisher
  • western blot; mouse; 1:500; fig 3d
Erikson J, Valente A, Mummidi S, Kandikattu H, Demarco V, Bender S, et al. Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling. J Biol Chem. 2017;292:2345-2358 pubmed publisher
K xf6 hler I, Bivik Eding C, Kasic N, Verma D, Enerb xe4 ck C. NOS2-derived low levels of NO drive psoriasis pathogenesis. Cell Death Dis. 2024;15:449 pubmed publisher
Baek H, Hong V, Kang H, Lee S, Lee J, Kang H, et al. Anti-rheumatic property and physiological safety of KMU-11342 in in vitro and in vivo models. Inflamm Res. 2024;73:1371-1391 pubmed publisher
Constantinesco N, Chinnappan B, Devito L, Moras C, Srikanth S, Garcia Hernandez M, et al. Sodium-Glucose Cotransporter-2 Inhibitor, Empagliflozin, Suppresses the Inflammatory Immune Response to Influenza Infection. Immunohorizons. 2023;7:861-871 pubmed publisher
Haba D, Ohmiya T, Sekino M, Qin Q, Takizawa C, Tomida S, et al. Efficacy of wearable vibration dressings on full-thickness wound healing in a hyperglycemic rat model. Wound Repair Regen. 2023;31:816-826 pubmed publisher
Gu L, Feng C, Li M, Hong Z, Di W, Qiu L. Exosomal NOX1 promotes tumor-associated macrophage M2 polarization-mediated cancer progression by stimulating ROS production in cervical cancer: a preliminary study. Eur J Med Res. 2023;28:323 pubmed publisher
Wu C, Cilic A, Pak O, Dartsch R, Wilhelm J, Wujak M, et al. CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD. Am J Respir Crit Care Med. 2023;207:1576-1590 pubmed publisher
Le Q, Zhang Z, Sun D, Cui Q, Yang X, Hassan A. Anti-inflammatory activities of two new deoxygenated N-acetyl glucosamines in lipopolysaccharide-activated mouse macrophage RAW264.7 cells. Heliyon. 2023;9:e15769 pubmed publisher
Schwarcz S, Kov xe1 cs P, Kov xe1 cs T, Ujlaki G, Nyerges P, Uray K, et al. The pro- and antineoplastic effects of deoxycholic acid in pancreatic adenocarcinoma cell models. Mol Biol Rep. 2023;50:5273-5282 pubmed publisher
x160 u x161 njara P, Mihaljevi x107 Z, Stupin A, Kolobari x107 N, Mati x107 A, Juki x107 I, et al. Consumption of Nutritionally Enriched Hen Eggs Enhances Endothelium-Dependent Vasodilation via Cyclooxygenase Metabolites in Healthy Young People-A Randomized Study. Nutrients. 2023;15: pubmed publisher
Lin C, Huang K, Kao S, Lin M, Lin C, Yang S, et al. Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response. Sci Adv. 2023;9:eade9944 pubmed publisher
Ren Y, Zhang S, Weeks J, Moreno J, He B, Xue T, et al. Reduced angiogenesis and delayed endochondral ossification in CD163-/- mice highlights a role of M2 macrophages during bone fracture repair. J Orthop Res. 2023;41:2384-2393 pubmed publisher
Vladimirova O, Soldan S, Su C, Kossenkov A, Ngalamika O, Tso F, et al. Elevated iNOS and 3'-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model. Tumour Virus Res. 2023;15:200259 pubmed publisher
Liu B, Kong Y, Alimi O, Kuss M, Tu H, Hu W, et al. Multifunctional Microgel-Based Cream Hydrogels for Postoperative Abdominal Adhesion Prevention. ACS Nano. 2023;17:3847-3864 pubmed publisher
Dravid A, Dhanabalan K, Naskar S, Vashistha A, Agarwal S, Padhan B, et al. Sustained release resolvin D1 liposomes are effective in the treatment of osteoarthritis in obese mice. J Biomed Mater Res A. 2023;111:765-777 pubmed publisher
Janani G, Zhang L, Badylak S, Mandal B. Silk fibroin bioscaffold from Bombyx mori and Antheraea assamensis elicits a distinct host response and macrophage activation paradigm in vivo and in vitro. Biomater Adv. 2023;145:213223 pubmed publisher
Lamorie Foote K, Liu Q, Shkirkova K, Ge B, He S, Morgan T, et al. Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice. J Neurosci Res. 2023;101:384-402 pubmed publisher
Kang R, Gamdzyk M, Luo Y, Tang H, Huang L, Lenahan C, et al. Three Days Delayed Recanalization Improved Neurological Function in pMCAO Rats by Increasing M2 Microglia-Possible Involvement of the IL-4R/STAT6/PPARγ Pathway. Transl Stroke Res. 2023;14:250-262 pubmed publisher
Zeng X, Chen B, Wang L, Sun Y, Jin Z, Liu X, et al. Chitosan@Puerarin hydrogel for accelerated wound healing in diabetic subjects by miR-29ab1 mediated inflammatory axis suppression. Bioact Mater. 2023;19:653-665 pubmed publisher
Kwon O, Lee S. Ishige okamurae Attenuates Neuroinflammation and Cognitive Deficits in Mice Intracerebroventricularly Injected with LPS via Regulating TLR-4/MyD88-Dependent Pathways. Antioxidants (Basel). 2022;12: pubmed publisher
Gredic M, Sharma V, Hadžić S, Wu C, Pak O, Kojonazarov B, et al. iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice. Cells. 2022;12: pubmed publisher
Song B, Chen C, Xu W, Cong B, Guo Z, Zhao Z, et al. Gender Differences in the Correlations Between Immune Cells and Organ Damage Indexes of Acute Myocardial Infarction Patients. Vasc Health Risk Manag. 2022;18:839-850 pubmed publisher
Fang Z, Hu Y, Dai J, He L, He J, Xu B, et al. CS12192, a Novel JAK3/JAK1/TBK1 Inhibitor, Synergistically Enhances the Anti-Inflammation Effect of Methotrexate in a Rat Model of Rheumatoid Arthritis. Int J Mol Sci. 2022;23: pubmed publisher
Kim J, Yang H, Go Y. Quercus acuta Thunb. Suppresses LPS-Induced Neuroinflammation in BV2 Microglial Cells via Regulating MAPK/NF-κB and Nrf2/HO-1 Pathway. Antioxidants (Basel). 2022;11: pubmed publisher
Gallinat A, Mendieta G, Vilahur G, Padr xf3 T, Badimon L. DJ-1 administration exerts cardioprotection in a mouse model of acute myocardial infarction. Front Pharmacol. 2022;13:1002755 pubmed publisher
Eo H, Lee S, Kim S, Ju I, Huh E, Lim J, et al. Petasites japonicus leaf extract inhibits Alzheimer's-like pathology through suppression of neuroinflammation. Food Funct. 2022;13:10811-10822 pubmed publisher
Qiang P, Hao J, Yang F, Han Y, Chang Y, Xian Y, et al. Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone. Front Immunol. 2022;13:948658 pubmed publisher
Raina K, Kandhari K, Jain A, Ravichandran K, Maroni P, Agarwal C, et al. Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model. Cancers (Basel). 2022;14: pubmed publisher
Nin x10d evi x107 V, Zjali x107 M, Kolari x107 T, Smoli x107 M, Kizivat T, Kuna L, et al. Renoprotective Effect of Liraglutide Is Mediated via the Inhibition of TGF-Beta 1 in an LLC-PK1 Cell Model of Diabetic Nephropathy. Curr Issues Mol Biol. 2022;44:1087-1114 pubmed publisher
Dravid A, M Dhanabalan K, Agarwal S, Agarwal R. Resolvin D1-loaded nanoliposomes promote M2 macrophage polarization and are effective in the treatment of osteoarthritis. Bioeng Transl Med. 2022;7:e10281 pubmed publisher
Zhu K, Wang Y, Sarlus H, Geng K, Nutma E, Sun J, et al. Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation. EMBO Rep. 2022;23:e54499 pubmed publisher
Carey R, Hariri B, Adappa N, Palmer J, Lee R. HSP90 Modulates T2R Bitter Taste Receptor Nitric Oxide Production and Innate Immune Responses in Human Airway Epithelial Cells and Macrophages. Cells. 2022;11: pubmed publisher
Park M, Goughnour P, Jun S, Cho S, Song E, Kim S, et al. Two distinct receptor-binding domains of human glycyl-tRNA synthetase 1 displayed on extracellular vesicles activate M1 polarization and phagocytic bridging of macrophages to cancer cells. Cancer Lett. 2022;539:215698 pubmed publisher
Kuek L, McMahon D, Ma R, Miller Z, Jolivert J, Adappa N, et al. Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Lee D, Kim J. P2X7 Receptor Augments LPS-Induced Nitrosative Stress by Regulating Nrf2 and GSH Levels in the Mouse Hippocampus. Antioxidants (Basel). 2022;11: pubmed publisher
Saclier M, Angelini G, Bonfanti C, Mura G, Temponi G, Messina G. Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro-adipogenic progenitor-dependent fibrosis. J Pathol. 2022;257:352-366 pubmed publisher
Cao L, Wang S, Zhang L, Li J. mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg3. Biomed Pharmacother. 2022;146:112608 pubmed publisher
Li Y, Acosta F, Quan Y, Li Z, Gu S, Jiang J. Studying macrophage activation in immune-privileged lens through CSF-1 protein intravitreal injection in mouse model. STAR Protoc. 2022;3:101060 pubmed publisher
Mou K, Shen K, Li Y, Wu Z, Duan W. Adenosine A2A Receptor in Bone Marrow-Derived Cells Mediated Macrophages M2 Polarization via PPARγ-P65 Pathway in Chronic Hypoperfusion Situation. Front Aging Neurosci. 2021;13:792733 pubmed publisher
Wang T, Zhu G, Qin L, Wang Q, She C, Xu D, et al. Kininogen-Nitric Oxide Signaling at Nearby Nonexcited Acupoints after Long-Term Stimulation. JID Innov. 2021;1:100038 pubmed publisher
Sp N, Kang D, Jo E, Lee J, Bae S, Jang K. Pivotal Role of Iron Homeostasis in the Induction of Mitochondrial Apoptosis by 6-Gingerol Through PTEN Regulated PD-L1 Expression in Embryonic Cancer Cells. Front Oncol. 2021;11:781720 pubmed publisher
Manigat L, Granade M, Taori S, Miller C, Vass L, Zhong X, et al. Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness. Front Immunol. 2021;12:722469 pubmed publisher
Zhou W, Lin Z, Xiong Y, Xue H, Song W, Yu T, et al. Dual-Targeted Nanoplatform Regulating the Bone Immune Microenvironment Enhances Fracture Healing. ACS Appl Mater Interfaces. 2021;13:56944-56960 pubmed publisher
Carey R, Adappa N, Palmer J, Lee R. Neuropeptide Y Reduces Nasal Epithelial T2R Bitter Taste Receptor-Stimulated Nitric Oxide Production. Nutrients. 2021;13: pubmed publisher
Zhou Q, Lin L, Li H, Wang H, Jiang S, Huang P, et al. Melatonin Reduces Neuroinflammation and Improves Axonal Hypomyelination by Modulating M1/M2 Microglia Polarization via JAK2-STAT3-Telomerase Pathway in Postnatal Rats Exposed to Lipopolysaccharide. Mol Neurobiol. 2021;58:6552-6576 pubmed publisher
Chow S, Cui C, Cheng K, Chim Y, Wang J, Wong C, et al. Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway. Int J Mol Sci. 2021;22: pubmed publisher
Wu J, Xu X, Zheng L, Mo J, Jin X, Bao Y. Nilotinib inhibits microglia-mediated neuroinflammation to protect against dopaminergic neuronal death in Parkinson's disease models. Int Immunopharmacol. 2021;99:108025 pubmed publisher
Yu H, Hou G, Cao J, Yin Y, Zhao Y, Cheng L. Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway. Oxid Med Cell Longev. 2021;2021:6632786 pubmed publisher
Jank xf3 L, Kov xe1 cs T, Laczik M, S xe1 ri Z, Ujlaki G, Kis G, et al. Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation. Cells. 2021;10: pubmed publisher
Jandova J, Snell J, Hua A, Dickinson S, Fimbres J, Wondrak G. Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin. Redox Biol. 2021;45:102042 pubmed publisher
Li Y, Li Z, Quan Y, Cheng H, Riquelme M, Li X, et al. Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis. iScience. 2021;24:102533 pubmed publisher
Sp N, Kang D, Kim H, Rugamba A, Jo E, Park J, et al. Natural Sulfurs Inhibit LPS-Induced Inflammatory Responses through NF-κB Signaling in CCD-986Sk Skin Fibroblasts. Life (Basel). 2021;11: pubmed publisher
Mouton A, Flynn E, Moak S, Aitken N, Omoto A, Li X, et al. Dimethyl fumarate preserves left ventricular infarct integrity following myocardial infarction via modulation of cardiac macrophage and fibroblast oxidative metabolism. J Mol Cell Cardiol. 2021;158:38-48 pubmed publisher
Bai B, Wu F, Ying K, Xu Y, Shan L, Lv Y, et al. Therapeutic effects of dihydroartemisinin in multiple stages of colitis-associated colorectal cancer. Theranostics. 2021;11:6225-6239 pubmed publisher
Seo M, Jo M, Hong N, Kim M, Shim K, Shin E, et al. Anti-Inflammatory and Anti-Vascular Leakage Effects by Combination of Centella asiatica and Vitis vinifera L. Leaf Extracts. Evid Based Complement Alternat Med. 2021;2021:7381620 pubmed publisher
Misra S, Kilari S, Yang B, Sharma A, Wu C, Vazquez Padron R, et al. Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model. J Am Soc Nephrol. 2021;: pubmed publisher
Zhang J, Saravanabavan S, Cheng K, Raghubanshi A, Chandra A, Munt A, et al. Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease. PLoS ONE. 2021;16:e0248400 pubmed publisher
Raisi A, Dezfoulian O, Davoodi F, Taheri S, Ghahremani S. Salvia miltiorrhiza hydroalcoholic extract inhibits postoperative peritoneal adhesions in rats. BMC Complement Med Ther. 2021;21:126 pubmed publisher
Ma X, Zhang Z, Shen M, Ma Y, Li R, Jin X, et al. Changes of type II collagenase biomarkers on IL-1β-induced rat articular chondrocytes. Exp Ther Med. 2021;21:582 pubmed publisher
Ahmad A, Fauzia E, Kumar M, Mishra R, Kumar A, Khan M, et al. Gelatin-Coated Polycaprolactone Nanoparticle-Mediated Naringenin Delivery Rescue Human Mesenchymal Stem Cells from Oxygen Glucose Deprivation-Induced Inflammatory Stress. ACS Biomater Sci Eng. 2019;5:683-695 pubmed publisher
Prpar Mihevc S, Zakošek Pipan M, Strbenc M, Rogelj B, Majdic G. Nitrosative Stress in the Frontal Cortex From Dogs With Canine Cognitive Dysfunction. Front Vet Sci. 2020;7:573155 pubmed publisher
Sári Z, Miko E, Kovacs T, Boratkó A, Ujlaki G, Jankó L, et al. Indoxylsulfate, a Metabolite of the Microbiome, Has Cytostatic Effects in Breast Cancer via Activation of AHR and PXR Receptors and Induction of Oxidative Stress. Cancers (Basel). 2020;12: pubmed publisher
Kim S, Park M, Kim J, Kim T, Hwang J, Ha K, et al. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia. Cells. 2020;9: pubmed publisher
Sári Z, Miko E, Kovacs T, Jankó L, Csonka T, Lente G, et al. Indolepropionic Acid, a Metabolite of the Microbiome, Has Cytostatic Properties in Breast Cancer by Activating AHR and PXR Receptors and Inducing Oxidative Stress. Cancers (Basel). 2020;12: pubmed publisher
Sutter C, Rainwater H, Sutter T. Contributions of Nitric Oxide to AHR-Ligand-Mediated Keratinocyte Differentiation. Int J Mol Sci. 2020;21: pubmed publisher
Cai C, Kilari S, Singh A, Zhao C, Simeon M, Misra A, et al. Differences in Transforming Growth Factor-β1/BMP7 Signaling and Venous Fibrosis Contribute to Female Sex Differences in Arteriovenous Fistulas. J Am Heart Assoc. 2020;9:e017420 pubmed publisher
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadžić S, et al. NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD. Nat Metab. 2020;2:532-546 pubmed publisher
Veetil A, Zou J, Henderson K, Jani M, Shaik S, Sisodia S, et al. DNA-based fluorescent probes of NOS2 activity in live brains. Proc Natl Acad Sci U S A. 2020;117:14694-14702 pubmed publisher
Kuai Y, Liu H, Liu D, Liu Y, Sun Y, Xie J, et al. An ultralow dose of the NADPH oxidase inhibitor diphenyleneiodonium (DPI) is an economical and effective therapeutic agent for the treatment of colitis-associated colorectal cancer. Theranostics. 2020;10:6743-6757 pubmed publisher
Hozain S, Cottrell J. CDllb+ targeted depletion of macrophages negatively affects bone fracture healing. Bone. 2020;138:115479 pubmed publisher
Fern xe1 ndez Garc xed a S, Sancho Balsells A, Longueville S, Herv xe9 D, Gruart A, Delgado Garc xed a J, et al. Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy. Cell Death Dis. 2020;11:411 pubmed publisher
Chang C, Chen J, Wu M, Hu M. Therapeutic treatment with vitamin C reduces focal cerebral ischemia-induced brain infarction in rats by attenuating disruptions of blood brain barrier and cerebral neuronal apoptosis. Free Radic Biol Med. 2020;155:29-36 pubmed publisher
Saclier M, Lapi M, Bonfanti C, Rossi G, Antonini S, Messina G. The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration. Cells. 2020;9: pubmed publisher
Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, et al. C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy. 2019;:1-16 pubmed publisher
Cai C, Zhao C, Kilari S, Sharma A, Singh A, Simeon M, et al. Effect of sex differences in treatment response to angioplasty in a murine arteriovenous fistula model. Am J Physiol Renal Physiol. 2020;318:F565-F575 pubmed publisher
Chow S, Chim Y, Wang J, Zhang N, Wong R, Tang N, et al. Vibration treatment modulates macrophage polarisation and enhances early inflammatory response in oestrogen-deficient osteoporotic-fracture healing. Eur Cell Mater. 2019;38:228-245 pubmed publisher
Do D, Mu J, Ke X, Sachdeva K, Qin Z, Wan M, et al. miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2. JCI Insight. 2019;4: pubmed publisher
Marek Iannucci S, Thomas A, Hou J, Crupi A, Sin J, Taylor D, et al. Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury. Sci Rep. 2019;9:10001 pubmed publisher
Singh K, Gobert A, Coburn L, Barry D, Allaman M, Asim M, et al. Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome. Front Cell Infect Microbiol. 2019;9:66 pubmed publisher
Ye J, Guan M, Lu Y, Zhang D, Li C, Li Y, et al. Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury by targeting MD2. Eur J Pharmacol. 2019;852:151-158 pubmed publisher
Wang C, Lin Y, Chang B, Chen C, Wu R, Lee C. Targeting the phosphorylation site of myristoylated alanine-rich C kinase substrate alleviates symptoms in a murine model of steroid-resistant asthma. Br J Pharmacol. 2019;176:1122-1134 pubmed publisher
Zhang H, Wei Q, Xiang X, Zhou B, Chen J, Li J, et al. Semaphorin 4A acts in a feed-forward loop with NF-κB pathway to exacerbate catabolic effect of IL-1β on chondrocytes. Int Immunopharmacol. 2019;69:88-94 pubmed publisher
Malhotra R, Wunderer F, Barnes H, Bagchi A, Buswell M, O Rourke C, et al. Hepcidin Deficiency Protects Against Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019;39:178-187 pubmed publisher
Yu Y, Park S, Beyak M. Inducible nitric oxide synthase-derived nitric oxide reduces vagal satiety signalling in obese mice. J Physiol. 2019;597:1487-1502 pubmed publisher
Zhang X, Zhao Y, Zhu X, Guo Y, Yang Y, Jiang Y, et al. Active vitamin D regulates macrophage M1/M2 phenotypes via the STAT-1-TREM-1 pathway in diabetic nephropathy. J Cell Physiol. 2019;234:6917-6926 pubmed publisher
Liu W, Li J, Cheng M, Wang Q, Yeung K, Chu P, et al. Zinc-Modified Sulfonated Polyetheretherketone Surface with Immunomodulatory Function for Guiding Cell Fate and Bone Regeneration. Adv Sci (Weinh). 2018;5:1800749 pubmed publisher
Zhu J, He J, Verano M, Brimmo A, Glia A, Qasaimeh M, et al. An integrated adipose-tissue-on-chip nanoplasmonic biosensing platform for investigating obesity-associated inflammation. Lab Chip. 2018;18:3550-3560 pubmed publisher
Lee S, Kim G, Kim N, Kim S, Ghosh P, Rhee D. ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection. Front Immunol. 2018;9:1954 pubmed publisher
Choi J, Yeo I, Kim K, Choi W, Jung J, Han S, et al. K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression. J Neuroinflammation. 2018;15:224 pubmed publisher
Shaalan A, Carpenter G, Proctor G. Inducible nitric oxide synthase-mediated injury in a mouse model of acute salivary gland dysfunction. Nitric Oxide. 2018;78:95-102 pubmed publisher
Hao Y, Niu H, An S, Wang M, Wang Z. Downregulation of iNOS, IL-1β, and P2X7 Expression in Mast Cells via Activation of PAR4 Contributes to the Inhibition of Visceral Hyperalgesia in Rats. J Immunol Res. 2018;2018:3256908 pubmed publisher
Gu S, Lee H, Ham Y, Son D, Kim H, Oh K, et al. Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway. Neuromolecular Med. 2018;20:312-327 pubmed publisher
Wang C, Wee H, Hu C, Chio C, Kuo J. The Effects of Memantine on Glutamic Receptor-Associated Nitrosative Stress in a Traumatic Brain Injury Rat Model. World Neurosurg. 2018;112:e719-e731 pubmed publisher
Shaalan A, Carpenter G, Proctor G. Caspases are key regulators of inflammatory and innate immune responses mediated by TLR3 in vivo. Mol Immunol. 2018;94:190-199 pubmed publisher
Choi J, Jang J, Son D, Im H, Kim J, Park J, et al. Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment. Int J Mol Sci. 2017;18: pubmed publisher
Choi J, Hwang C, Lee D, Gu S, Lee H, Choi D, et al. (E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates LPS-Mediated Memory Impairment by Inhibition of STAT3 Pathway. Neuromolecular Med. 2017;19:555-570 pubmed publisher
Masola V, Zaza G, Bellin G, Dall Olmo L, Granata S, Vischini G, et al. Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury. FASEB J. 2018;32:742-756 pubmed publisher
Moriwaki K, Asahi M. Augmented TME O-GlcNAcylation Promotes Tumor Proliferation through the Inhibition of p38 MAPK. Mol Cancer Res. 2017;15:1287-1298 pubmed publisher
Hariri B, McMahon D, Chen B, Freund J, Mansfield C, Doghramji L, et al. Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem. 2017;292:8484-8497 pubmed publisher
Waniczek D, Lorenc Z, Snietura M, Wesecki M, Kopec A, Muc Wierzgoń M. Tumor-Associated Macrophages and Regulatory T Cells Infiltration and the Clinical Outcome in Colorectal Cancer. Arch Immunol Ther Exp (Warsz). 2017;65:445-454 pubmed publisher
Kim Y, Hwang C, Lee H, Kim C, Son D, Ham Y, et al. Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB. Neuropharmacology. 2017;117:21-32 pubmed publisher
Ridiandries A, Tan J, Ravindran D, Williams H, Medbury H, Lindsay L, et al. CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis. FASEB J. 2017;31:1179-1192 pubmed publisher
Humbert Claude M, Duc D, Dwir D, Thieren L, Sandström von Tobel J, Begka C, et al. Tollip, an early regulator of the acute inflammatory response in the substantia nigra. J Neuroinflammation. 2016;13:303 pubmed
Li M, Qian S. Gastrodin Protects Neural Progenitor Cells Against Amyloid ? (1-42)-Induced Neurotoxicity and Improves Hippocampal Neurogenesis in Amyloid ? (1-42)-Injected Mice. J Mol Neurosci. 2016;60:21-32 pubmed publisher
Wezel A, De Vries M, Maassen J, Kip P, Peters E, Karper J, et al. Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response. Sci Rep. 2016;6:24248 pubmed publisher
Kim H, Yoo H, Jang J, Lin H, Seo E, Zhang Y, et al. Wall stretch and thromboxane Aâ‚‚ activate NO synthase (eNOS) in pulmonary arterial smooth muscle cells via Hâ‚‚Oâ‚‚ and Akt-dependent phosphorylation. Pflugers Arch. 2016;468:705-16 pubmed publisher
Yun J, Gu S, Yun H, Son D, Park M, Lee M, et al. Myelin oligodendrocyte glycoprotein (MOG35-55)-induced experimental autoimmune encephalomyelitis is ameliorated in interleukin-32 alpha transgenic mice. Oncotarget. 2015;6:40452-63 pubmed publisher
Kober C, Rohn S, Weibel S, Geissinger U, Chen N, Szalay A. Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps. J Transl Med. 2015;13:216 pubmed publisher
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product information
master code :
NB300-605
SKU :
NB300-605
product name :
iNOS Antibody - BSA Free
unit size :
200 uL (also 0.04 ml)
description :
The iNOS Antibody - BSA Free from Novus is a rabbit polyclonal antibody to iNOS. This antibody reacts with human,mouse,porcine,rat. The iNOS Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,In vitro assay.
target :
iNOS
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Sythetic peptide made to an internal portion of mouse iNOS (between amino acids 12-48) [UniProt P29477].
isotype :
IgG
purity :
Affinity purified
species :
Human,Mouse,Porcine,Rat
specificity :
This antibody detects iNOS
theoretical molecular weight :
131 kDa
gene symbol :
NOS2
Antibody validation :
Biological Validation
accessionNumbers :
P29477
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,In vitro assay
USD :
419 USD
alt names :
EC 1.14.13.39, Hepatocyte NOS, HEP-NOS, Inducible NO synthase, Inducible NOS, INOS, nitric oxide synthase 2, inducible, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, NOS, NOS type II, NOS2A, Peptidyl-cysteine S-nitrosylase NOS2
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.