product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LAMP-2/CD107b Antibody
catalog :
NB300-591
quantity :
100 uL (also 0.025 ml)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 26
Reference
Niskanen J, Peltonen S, Ohtonen S, Fazaludeen M, Luk K, Giudice L, et al. Uptake of alpha-synuclein preformed fibrils is suppressed by inflammation and induces an aberrant phenotype in human microglia. Glia. 2025;73:159-174 pubmed publisher
Xu J, Xiong A, Wang X, Yan X, Chen Y, Ye X, et al. Hyperoside attenuates pyrrolizidine alkaloids-induced liver injury by ameliorating TFEB-mediated mitochondrial dysfunction. Arch Pharm Res. 2023;46:694-712 pubmed publisher
Barcena M, Tonini G, Haritonow N, Breiter P, Milting H, Baczkó I, et al. Sex and age differences in AMPK phosphorylation, mitochondrial homeostasis, and inflammation in hearts from inflammatory cardiomyopathy patients. Aging Cell. 2023;22:e13894 pubmed publisher
Eshima H, Shahtout J, Siripoksup P, Pearson M, Mahmassani Z, Ferrara P, et al. Lipid hydroperoxides promote sarcopenia through carbonyl stress. elife. 2023;12: pubmed publisher
Guo L, Reed K, Carter A, Cheng Y, Roodsari S, Martinez Pineda D, et al. Sleep-Disturbance-Induced Microglial Activation Involves CRH-Mediated Galectin 3 and Autophagy Dysregulation. Cells. 2022;12: pubmed publisher
Shearn C, Anderson A, Devereux M, Orlicky D, Michel C, Petersen D, et al. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS ONE. 2022;17:e0276879 pubmed publisher
Cheng Y, Kim W, Wellman L, Sanford L, Guo M. Short-Term Sleep Fragmentation Dysregulates Autophagy in a Brain Region-Specific Manner. Life (Basel). 2021;11: pubmed publisher
Guo M, Chivero E, Callen S, Buch S. NLRP3 Inflammasome Is Involved in Cocaine-Mediated Potentiation on Behavioral Changes in CX3CR1-Deficient Mice. J Pers Med. 2021;11: pubmed publisher
Tripathi A, Thangaraj A, Chivero E, Periyasamy P, Burkovetskaya M, Niu F, et al. N-Acetylcysteine Reverses Antiretroviral-Mediated Microglial Activation by Attenuating Autophagy-Lysosomal Dysfunction. Front Neurol. 2020;11:840 pubmed publisher
Chivero E, Liao K, Niu F, Tripathi A, Tian C, Buch S, et al. Engineered Extracellular Vesicles Loaded With miR-124 Attenuate Cocaine-Mediated Activation of Microglia. Front Cell Dev Biol. 2020;8:573 pubmed publisher
Tripathi A, Thangaraj A, Chivero E, Periyasamy P, Callen S, Burkovetskaya M, et al. Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction. Cells. 2019;8: pubmed publisher
Singatulina A, Hamon L, Sukhanova M, Desforges B, Joshi V, Bouhss A, et al. PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA. Cell Rep. 2019;27:1809-1821.e5 pubmed publisher
Martínez Macías M, Moore D, Green R, Gómez Herreros F, Naumann M, Hermann A, et al. FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress. Life Sci Alliance. 2019;2: pubmed publisher
Gittings L, Foti S, Benson B, Gami Patel P, Isaacs A, Lashley T. Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS. Acta Neuropathol Commun. 2019;7:18 pubmed publisher
Cohignac V, Landry M, Ridoux A, Pinault M, Annangi B, Gerdil A, et al. Carbon nanotubes, but not spherical nanoparticles, block autophagy by a shape-related targeting of lysosomes in murine macrophages. Autophagy. 2018;14:1323-1334 pubmed publisher
Cheng X, Xie Y, Zhou B, Huang N, Farfel Becker T, Sheng Z. Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons. J Cell Biol. 2018;217:3127-3139 pubmed publisher
Pansarasa O, Bordoni M, Drufuca L, Diamanti L, Sproviero D, Trotti R, et al. Lymphoblastoid cell lines as a model to understand amyotrophic lateral sclerosis disease mechanisms. Dis Model Mech. 2018;11: pubmed publisher
Ikehata N, Takanashi M, Satomi T, Watanabe M, Hasegawa O, Kono M, et al. Toll-like receptor 2 activation implicated in oral squamous cell carcinoma development. Biochem Biophys Res Commun. 2018;495:2227-2234 pubmed publisher
Antoniou A, Khudayberdiev S, Idziak A, Bicker S, Jacob R, Schratt G. The dynamic recruitment of TRBP to neuronal membranes mediates dendritogenesis during development. EMBO Rep. 2018;19: pubmed publisher
Prpar Mihevc S, Pavlin M, Darovic S, Živin M, Podbregar M, Rogelj B, et al. Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle. J Mol Neurosci. 2017;62:318-328 pubmed publisher
Lojk J, Prpar Mihevc S, Bregar V, Pavlin M, Rogelj B. The Effect of Different Types of Nanoparticles on FUS and TDP-43 Solubility and Subcellular Localization. Neurotox Res. 2017;32:325-339 pubmed publisher
Sim Y, Park G, Eo H, Huh E, Gu P, Hong S, et al. Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. Neuroscience. 2017;340:166-175 pubmed publisher
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product information
master code :
NB300-591
SKU :
NB300-591
product name :
LAMP-2/CD107b Antibody
unit size :
100 uL (also 0.025 ml)
description :
The LAMP-2/CD107b Antibody from Novus is a rabbit polyclonal antibody to LAMP-2/CD107b. This antibody reacts with human,mouse,rat. The LAMP-2/CD107b Antibody has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry.
target :
LAMP-2/CD107b
category :
Primary Antibodies
buffer :
PBS with 1 mg/ml BSA
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
LAMP-2/CD107b Antibody was made using a synthetic Peptide: CG (400) LKRHHTGYEQF(411)
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
LAMP 2
gene symbol :
LAMP2
applications :
Immunocytochemistry/ Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry
USD :
469 USD
alt names :
CD107 antigen-like family member B, CD107b, CD107b antigen, LAMP2, LAMP-2, LAMP2A, LAMP-2A, LAMPB, LGP110, LGP-96, Lysosomal Associated Membrane Protein 2, lysosomal-associated membrane protein 2, lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.