SERCA2 ATPase Antibody (2A7-A1) | Novus Biologicals NB300-581 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

SERCA2 ATPase Antibody (2A7-A1)

catalog :

NB300-581

quantity :

100 uL (also 0.01 ml)

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A7-A1

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 49

Reference
Uchida Y, Yamamoto Y, Sakisaka T. Trans-2-enoyl-CoA reductase limits Ca2+ accumulation in the endoplasmic reticulum by inhibiting the Ca2+ pump SERCA2b. J Biol Chem. 2021;:100310 pubmed publisher
Jiang F, Zhang W, Zhou M, Zhou Z, Shen M, Chen N, et al. Human amniotic mesenchymal stromal cells promote bone regeneration via activating endogenous regeneration. Theranostics. 2020;10:6216-6230 pubmed publisher
Xie D, Geng L, Xiong K, Zhao T, Wang S, Xue J, et al. Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase. Circ Res. 2020;126:1706-1720 pubmed publisher
Langendorf E, Klein A, Drees P, Rommens P, Mattyasovszky S, Ritz U. Exposure to radial extracorporeal shockwaves induces muscle regeneration after muscle injury in a surgical rat model. J Orthop Res. 2020;38:1386-1397 pubmed publisher
Qayoom A, Aneesha V, Anagha S, Javeed A, Kumar P, Kumar D. Lecithin-based deferoxamine nanoparticles accelerated cutaneous wound healing in diabetic rats. Eur J Pharmacol. 2019;:172478 pubmed publisher
Wang L, Wang F, Zhao L, Yang W, Wan X, Yue C, et al. Mesenchymal Stem Cells Coated by the Extracellular Matrix Promote Wound Healing in Diabetic Rats. Stem Cells Int. 2019;2019:9564869 pubmed publisher
Chung Y, Luo A, Park K, Loonat A, Lakhal Littleton S, Robbins P, et al. Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity. JCI Insight. 2019;4: pubmed publisher
Matsuyoshi Y, Akahoshi M, Nakamura M, Tatsumi R, Mizunoya W. Isolation and Purification of Satellite Cells from Young Rats by Percoll Density Gradient Centrifugation. Methods Mol Biol. 2019;1889:81-93 pubmed publisher
Jiang K, Chaimov D, Patel S, Liang J, Wiggins S, Samojlik M, et al. 3-D physiomimetic extracellular matrix hydrogels provide a supportive microenvironment for rodent and human islet culture. Biomaterials. 2019;198:37-48 pubmed publisher
Chen B, Zhang J, Nie D, Zhao G, Fu F, Wang J. Characterization of the structure of rabbit anterior cruciate ligament and its stem/progenitor cells. J Cell Biochem. 2018;: pubmed publisher
Sung J, Corben A, Brooks J, Edelweiss M, Keating D, Lin C, et al. Histopathologic characteristics of background parenchymal enhancement (BPE) on breast MRI. Breast Cancer Res Treat. 2018;172:487-496 pubmed publisher
Nadolski G, Hunt S, Weber C, Mohammed M, Pulido S, Noji M, et al. Near-Infrared Fluorescence Imaging of Matrix Metalloproteinase 2 Activity as a Biomarker of Vascular Remodeling in Hemodialysis Access. J Vasc Interv Radiol. 2018;29:1268-1275.e1 pubmed publisher
Xing S, Pan N, Xu W, Zhang J, Li J, Dang C, et al. EphrinB2 activation enhances angiogenesis, reduces amyloid-? deposits and secondary damage in thalamus at the early stage after cortical infarction in hypertensive rats. J Cereb Blood Flow Metab. 2018;:271678X18769188 pubmed publisher
Mantani Y, Nishida M, Yamamoto K, Miyamoto K, Yuasa H, Masuda N, et al. Ultrastructural and Immunohistochemical Study on the Lamina Propria Cells Beneath Paneth Cells in the Rat Ileum. Anat Rec (Hoboken). 2018;301:1074-1085 pubmed publisher
Eltony S, Abdelhameed S. Effect of chronic administration of sildenafil citrate (Viagra) on the histology of the retina and optic nerve of adult male rat. Tissue Cell. 2017;49:323-335 pubmed publisher
Pacheco Quinto J, Eckman C, Eckman E. Major amyloid-Î²-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex. Neurobiol Aging. 2016;48:83-92 pubmed publisher
Robbins A, Mateson A, Khandha A, Pugarelli J, Buchanan T, Akins R, et al. Fetal Rat Gubernaculum Mesenchymal Cells Adopt Myogenic and Myofibroblast-Like Phenotypes. J Urol. 2016;196:270-8 pubmed publisher
Ram M, Singh V, Kumawat S, Kant V, Tandan S, Kumar D. Bilirubin modulated cytokines, growth factors and angiogenesis to improve cutaneous wound healing process in diabetic rats. Int Immunopharmacol. 2016;30:137-149 pubmed publisher
Ram M, Singh V, Kumawat S, Kumar D, Lingaraju M, Uttam Singh T, et al. Deferoxamine modulates cytokines and growth factors to accelerate cutaneous wound healing in diabetic rats. Eur J Pharmacol. 2015;764:9-21 pubmed publisher
Kant V, Gopal A, Kumar D, Pathak N, Ram M, Jangir B, et al. Curcumin-induced angiogenesis hastens wound healing in diabetic rats. J Surg Res. 2015;193:978-88 pubmed publisher
Xue S, Wu G, Zhang H, Guo Y, Zou Y, Zhou Z, et al. Transplantation of adipocyte-derived stem cells in a hydrogel scaffold for the repair of cortical contusion injury in rats. J Neurotrauma. 2015;32:506-15 pubmed publisher
Li W, Zhao R, Liu J, Tian M, Lu Y, He T, et al. Small islets transplantation superiority to large ones: implications from islet microcirculation and revascularization. J Diabetes Res. 2014;2014:192093 pubmed publisher
Gopal A, Kant V, Gopalakrishnan A, Tandan S, Kumar D. Chitosan-based copper nanocomposite accelerates healing in excision wound model in rats. Eur J Pharmacol. 2014;731:8-19 pubmed publisher
Kant V, Gopal A, Kumar D, Gopalkrishnan A, Pathak N, Kurade N, et al. Topical pluronic F-127 gel application enhances cutaneous wound healing in rats. Acta Histochem. 2014;116:5-13 pubmed publisher
Schroeder M, Ali M, Hulikova A, Supuran C, Clarke K, Vaughan Jones R, et al. Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. Proc Natl Acad Sci U S A. 2013;110:E958-67 pubmed publisher
Klug D, Boulé S, Wissocque L, Montaigne D, Marechal X, Hassoun S, et al. Right ventricular pacing with mechanical dyssynchrony causes apoptosis interruptus and calcium mishandling. Can J Cardiol. 2013;29:510-8 pubmed publisher
Salehi Had H, Roh M, Giani A, Hisatomi T, Nakao S, Kim I, et al. Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization. PLoS ONE. 2011;6:e18864 pubmed publisher
Nakao A, Huang C, Stolz D, Wang Y, Franks J, Tochigi N, et al. Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts. Cardiovasc Res. 2011;89:457-63 pubmed publisher
Willis C, Meske D, Davis T. Protein kinase C activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxygenation. J Cereb Blood Flow Metab. 2010;30:1847-59 pubmed publisher
Lochhead J, McCaffrey G, Quigley C, Finch J, Demarco K, Nametz N, et al. Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation. J Cereb Blood Flow Metab. 2010;30:1625-36 pubmed publisher
Thebault P, Lhermite N, Tilly G, Le Texier L, Quillard T, Heslan M, et al. The C-type lectin-like receptor CLEC-1, expressed by myeloid cells and endothelial cells, is up-regulated by immunoregulatory mediators and moderates T cell activation. J Immunol. 2009;183:3099-108 pubmed publisher
Stevenson K, McGlynn L, Hodge M, McLinden H, George W, Davies R, et al. Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations. Stem Cells Dev. 2009;18:1389-98 pubmed publisher
Schilte M, Loureiro J, Keuning E, Ter Wee P, Celie J, Beelen R, et al. Long-term intervention with heparins in a rat model of peritoneal dialysis. Perit Dial Int. 2009;29:26-35 pubmed
Garcia Perez C, Hajnoczky G, Csordás G. Physical coupling supports the local Ca2+ transfer between sarcoplasmic reticulum subdomains and the mitochondria in heart muscle. J Biol Chem. 2008;283:32771-80 pubmed publisher
Ohnishi T, Arnold L, Clark N, Wisecarver J, Cohen S. Comparison of endothelial cell proliferation in normal liver and adipose tissue in B6C3F1 mice, F344 rats, and humans. Toxicol Pathol. 2007;35:904-9 pubmed
Fujimoto K, Tobita K, Merryman W, Guan J, Momoi N, Stolz D, et al. An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in subacute myocardial infarction. J Am Coll Cardiol. 2007;49:2292-300 pubmed
Anyatonwu G, Estrada M, Tian X, Somlo S, Ehrlich B. Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. Proc Natl Acad Sci U S A. 2007;104:6454-9 pubmed
Wilson E, Jackson S, Cruwys S, Kerry P. An evaluation of the immunohistochemistry benefits of boric acid antigen retrieval on rat decalcified joint tissues. J Immunol Methods. 2007;322:137-42 pubmed
Prasad A, Ma H, Sumbilla C, Lee D, Klein M, Inesi G. Phenylephrine hypertrophy, Ca2+-ATPase (SERCA2), and Ca2+ signaling in neonatal rat cardiac myocytes. Am J Physiol Cell Physiol. 2007;292:C2269-75 pubmed
Ott I, Keller U, Knoedler M, Götze K, Doss K, Fischer P, et al. Endothelial-like cells expanded from CD34+ blood cells improve left ventricular function after experimental myocardial infarction. FASEB J. 2005;19:992-4 pubmed
Khan S, Lee K, Minhas K, Gonzalez D, Raju S, Tejani A, et al. Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. Proc Natl Acad Sci U S A. 2004;101:15944-8 pubmed
Krizaj D, Liu X, Copenhagen D. Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum). J Comp Neurol. 2004;475:463-80 pubmed
Nakao A, Kimizuka K, Stolz D, Neto J, Kaizu T, Choi A, et al. Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol. 2003;163:1587-98 pubmed
Spragg D, Leclercq C, Loghmani M, Faris O, Tunin R, Disilvestre D, et al. Regional alterations in protein expression in the dyssynchronous failing heart. Circulation. 2003;108:929-32 pubmed
Haywood L, McWilliams D, Pearson C, Gill S, Ganesan A, Wilson D, et al. Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum. 2003;48:2173-7 pubmed
Seegers H, Hood V, Kidd B, Cruwys S, Walsh D. Enhancement of angiogenesis by endogenous substance P release and neurokinin-1 receptors during neurogenic inflammation. J Pharmacol Exp Ther. 2003;306:8-12 pubmed
Tupling A, Asahi M, MacLennan D. Sarcolipin overexpression in rat slow twitch muscle inhibits sarcoplasmic reticulum Ca2+ uptake and impairs contractile function. J Biol Chem. 2002;277:44740-6 pubmed
Asahi M, Kurzydlowski K, Tada M, MacLennan D. Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs). J Biol Chem. 2002;277:26725-8 pubmed
Kielian T, Hickey W. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development. Am J Pathol. 2000;157:647-58 pubmed

product information

brand :

Novus

MasterCode :

NB300-581

SKU :

NB300-581

product name :

SERCA2 ATPase Antibody (2A7-A1)

unit sizes :

100 uL (also 0.01 ml)

description :

The SERCA2 ATPase Antibody (2A7-A1) from Novus is a mouse monoclonal antibody to SERCA2 ATPase. This antibody reacts with human, mouse, rat, porcine, amphibian, canine, guinea pig, rabbit, sheep. The SERCA2 ATPase Antibody (2A7-A1) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

target :

SERCA2 ATPase

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

2A7-A1

conjugate :

Unconjugated

host :

Mouse

immunogen :

Purified canine cardiac sarcoplasmic reticulum vesicles.

isotype :

IgG2a

purity :

Unpurified

species :

Human, Mouse, Rat, Porcine, Amphibian, Canine, Guinea Pig, Rabbit, Sheep

specificity :

Detects sarcoplasmic or endoplasmic reticulum calcium (SERCA) 2 ATPase. NB300-581 recognizes the SERCA2a and SERCA2b isoforms identically. However, the antibody does not recognize the skeletal muscle (SERCA1) or housekeeping isoforms (SERCA3).

gene symbol :

ATP2A2

accessionNumbers :

O46674

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

USD :

349 USD

alt names :

ATP2BFLJ20293, ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform, cardiac Ca2+ ATPase, DAR, DD, EC 3.6.3, EC 3.6.3.8, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, FLJ38063, MGC45367, sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2DKFZp686P0211, SR Ca(2+)-ATPase 2

storage :

Store at -20C. Avoid freeze-thaw cycles.