SERCA2 ATPase Antibody (2A7-A1) | Novus Biologicals NB300-581-10uL product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

SERCA2 ATPase Antibody (2A7-A1)

catalog :

NB300-581-10uL

quantity :

10 uL (also 100 uL)

price :

199 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A7-A1

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 16

Reference
Courjaret R, Wagner L, Ammouri R, Yule D, Machaca K. Ca2+ tunneling architecture and function are important for secretion. J Cell Biol. 2025;224: pubmed publisher
Tanton H, Sewastianik T, Seo H, Remillard D, Pierre R, Bala P, et al. A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. Sci Adv. 2022;8:eabm3108 pubmed publisher
Hammad A, Yu F, Botheju W, Elmi A, Alcantara Adap E, Machaca K. Phosphorylation of STIM1 at ERK/CDK sites is dispensable for cell migration and ER partitioning in mitosis. Cell Calcium. 2021;100:102496 pubmed publisher
Uchida Y, Yamamoto Y, Sakisaka T. Trans-2-enoyl-CoA reductase limits Ca2+ accumulation in the endoplasmic reticulum by inhibiting the Ca2+ pump SERCA2b. J Biol Chem. 2021;:100310 pubmed publisher
Xie D, Geng L, Xiong K, Zhao T, Wang S, Xue J, et al. Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase. Circ Res. 2020;126:1706-1720 pubmed publisher
Chung Y, Luo A, Park K, Loonat A, Lakhal Littleton S, Robbins P, et al. Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity. JCI Insight. 2019;4: pubmed publisher
Schroeder M, Ali M, Hulikova A, Supuran C, Clarke K, Vaughan Jones R, et al. Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. Proc Natl Acad Sci U S A. 2013;110:E958-67 pubmed publisher
Klug D, Boulé S, Wissocque L, Montaigne D, Marechal X, Hassoun S, et al. Right ventricular pacing with mechanical dyssynchrony causes apoptosis interruptus and calcium mishandling. Can J Cardiol. 2013;29:510-8 pubmed publisher
Garcia Perez C, Hajnoczky G, Csordás G. Physical coupling supports the local Ca2+ transfer between sarcoplasmic reticulum subdomains and the mitochondria in heart muscle. J Biol Chem. 2008;283:32771-80 pubmed publisher
Anyatonwu G, Estrada M, Tian X, Somlo S, Ehrlich B. Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. Proc Natl Acad Sci U S A. 2007;104:6454-9 pubmed
Prasad A, Ma H, Sumbilla C, Lee D, Klein M, Inesi G. Phenylephrine hypertrophy, Ca2+-ATPase (SERCA2), and Ca2+ signaling in neonatal rat cardiac myocytes. Am J Physiol Cell Physiol. 2007;292:C2269-75 pubmed
Khan S, Lee K, Minhas K, Gonzalez D, Raju S, Tejani A, et al. Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. Proc Natl Acad Sci U S A. 2004;101:15944-8 pubmed
Krizaj D, Liu X, Copenhagen D. Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum). J Comp Neurol. 2004;475:463-80 pubmed
Spragg D, Leclercq C, Loghmani M, Faris O, Tunin R, Disilvestre D, et al. Regional alterations in protein expression in the dyssynchronous failing heart. Circulation. 2003;108:929-32 pubmed
Tupling A, Asahi M, MacLennan D. Sarcolipin overexpression in rat slow twitch muscle inhibits sarcoplasmic reticulum Ca2+ uptake and impairs contractile function. J Biol Chem. 2002;277:44740-6 pubmed
Asahi M, Kurzydlowski K, Tada M, MacLennan D. Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs). J Biol Chem. 2002;277:26725-8 pubmed

product information

master code :

NB300-581

SKU :

NB300-581-10uL

product name :

SERCA2 ATPase Antibody (2A7-A1)

unit size :

10 uL (also 100 uL)

description :

The SERCA2 ATPase Antibody (2A7-A1) from Novus is a mouse monoclonal antibody to SERCA2 ATPase. This antibody reacts with amphibian,canine,guinea pig,human,mouse,porcine,rabbit,rat,sheep. The SERCA2 ATPase Antibody (2A7-A1) has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

SERCA2 ATPase

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

2A7-A1

conjugate :

Unconjugated

host :

Mouse

immunogen :

Purified canine cardiac sarcoplasmic reticulum vesicles.

isotype :

IgG2a

purity :

Unpurified

species :

Amphibian,Canine,Guinea Pig,Human,Mouse,Porcine,Rabbit,Rat,Sheep

specificity :

Detects sarcoplasmic or endoplasmic reticulum calcium (SERCA) 2 ATPase

gene symbol :

ATP2A2

accessionNumbers :

O46674

applications :

IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

199 USD

alt names :

ATP2BFLJ20293, ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform, cardiac Ca2+ ATPase, DAR, DD, EC 3.6.3, EC 3.6.3.8, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, FLJ38063, MGC45367, sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2DKFZp686P0211, SR Ca(2+)-ATPase 2

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage