TGN38 Antibody (2F7.1) | Novus Biologicals NB300-575 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TGN38 Antibody (2F7.1)

catalog :

NB300-575

quantity :

100 uL (also 0.02 ml)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F7.1

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 27

Reference
Andreska T, L xfc ningschr xf6 r P, Wolf D, McFleder R, Ayon Olivas M, Rattka M, et al. DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons. Cell Rep. 2023;42:112575 pubmed publisher
J Tisdale E, R Artalejo C. Rab2 stimulates LC3 lipidation on secretory membranes by noncanonical autophagy. Exp Cell Res. 2023;429:113635 pubmed publisher
Boyer C, Bauchle C, Zhang J, Wang Y, Stephens S. Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia. Sci Rep. 2023;13:5218 pubmed publisher
Maruo K, Nishiyama M, Honda Y, Cao A, Gao W, Shibata K, et al. Increased GLUT1 expression and localization to Golgi apparatus of acinar cells in the parotid gland of Goto-Kakizaki diabetic rats. Arch Oral Biol. 2023;146:105601 pubmed publisher
Rohli K, Boyer C, Bearrows S, Moyer M, Elison W, Bauchle C, et al. ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell. Function (Oxf). 2022;3:zqac051 pubmed publisher
Parchure A, Tian M, Stalder D, Boyer C, Bearrows S, Rohli K, et al. Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules. J Cell Biol. 2022;221: pubmed publisher
Kamat V, Radtke J, Hu Q, Wang W, Sweet I, Hampe C. Autoantibodies directed against glutamate decarboxylase interfere with glucose-stimulated insulin secretion in dispersed rat islets. Int J Exp Pathol. 2022;103:140-148 pubmed publisher
Li M, Shao F, Qian Q, Yu W, Zhang Z, Chen B, et al. A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells. Mol Ther Nucleic Acids. 2021;26:307-320 pubmed publisher
Casas M, Fadó R, Dominguez J, Roig A, Kaku M, Chohnan S, et al. Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking. J Cell Biol. 2020;219: pubmed publisher
Taverner A, MacKay J, Laurent F, Hunter T, Liu K, Mangat K, et al. Cholix protein domain I functions as a carrier element for efficient apical to basal epithelial transcytosis. Tissue Barriers. 2020;8:1710429 pubmed publisher
Bearrows S, Bauchle C, Becker M, Haldeman J, Swaminathan S, Stephens S. Chromogranin B regulates early stage insulin granule trafficking from the Golgi in pancreatic islet β-cells. J Cell Sci. 2019;: pubmed publisher
Tao T, Sun J, Peng Y, Li Y, Wang P, Chen X, et al. Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth. J Biol Chem. 2019;294:10954-10968 pubmed publisher
Alsalem J, Patel D, Susarla R, Coca Prados M, Bland R, Walker E, et al. Characterization of vitamin D production by human ocular barrier cells. Invest Ophthalmol Vis Sci. 2014;55:2140-7 pubmed publisher
de Haro M, Al Ramahi I, Jones K, Holth J, Timchenko L, Botas J. Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy. PLoS Genet. 2013;9:e1003445 pubmed publisher
Xiao Q, Ford A, Xu J, Yan P, Lee K, Gonzales E, et al. Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia. J Neurosci. 2012;32:13587-96 pubmed
Szmydynger Chodobska J, Strazielle N, Gandy J, Keefe T, Zink B, Ghersi Egea J, et al. Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier. J Cereb Blood Flow Metab. 2012;32:93-104 pubmed publisher
Ward A, Rimer M, Killian J, Dowling J, Cooper T. CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Hum Mol Genet. 2010;19:3614-22 pubmed publisher
Szmydynger Chodobska J, Fox L, Lynch K, Zink B, Chodobski A. Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injury. J Neurotrauma. 2010;27:1449-61 pubmed publisher
Mikhaylova M, Reddy P, Munsch T, Landgraf P, Suman S, Smalla K, et al. Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking. Proc Natl Acad Sci U S A. 2009;106:9093-8 pubmed publisher
Hashem V, Galloway J, Mori M, Willemsen R, Oostra B, Paylor R, et al. Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet. 2009;18:2443-51 pubmed publisher
Orengo J, Chambon P, Metzger D, Mosier D, Snipes G, Cooper T. Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci U S A. 2008;105:2646-51 pubmed publisher
Kress C, Gautier Courteille C, Osborne H, Babinet C, Paillard L. Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice. Mol Cell Biol. 2007;27:1146-57 pubmed
Lin X, Miller J, Mankodi A, Kanadia R, Yuan Y, Moxley R, et al. Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy. Hum Mol Genet. 2006;15:2087-97 pubmed
Mankodi A, Lin X, Blaxall B, Swanson M, Thornton C. Nuclear RNA foci in the heart in myotonic dystrophy. Circ Res. 2005;97:1152-5 pubmed
Mankodi A, Teng Umnuay P, Krym M, Henderson D, Swanson M, Thornton C. Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2. Ann Neurol. 2003;54:760-8 pubmed
Savkur R, Philips A, Cooper T. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nat Genet. 2001;29:40-7 pubmed
Good P, Chen Q, Warner S, Herring D. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. J Biol Chem. 2000;275:28583-92 pubmed

product information

master code :

NB300-575

SKU :

NB300-575

product name :

TGN38 Antibody (2F7.1)

unit size :

100 uL (also 0.02 ml)

description :

The TGN38 Antibody (2F7.1) from Novus is a mouse monoclonal antibody to TGN38. This antibody reacts with chinese hamster,human,monkey,mouse,rabbit,rat. The TGN38 Antibody (2F7.1) has been validated for the following applications: IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry.

target :

TGN38

category :

Primary Antibodies

buffer :

PBS, 1 mg/mL BSA

clonality :

Monoclonal

clone :

2F7.1

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Synthetic peptide corresponding to residues L(18) P S A S K P N N T S S E N N P P(34) C of rat TGN38.

isotype :

IgG1

purity :

Protein A or G purified

species :

Chinese Hamster,Human,Monkey,Mouse,Rabbit,Rat

specificity :

Detects Trans Golgi Network (TGN) 38 from human and monkey samples and both recombinant and endogenous rat samples

gene symbol :

TGOLN2

applications :

IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry

USD :

449 USD

alt names :

TGN46TGN38 homolog, TGN48MGC14722, TGN5148, 51kD isoforms), trans-golgi network protein 2, Trans-Golgi network protein TGN51

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage