product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Ryanodine Receptor Antibody (34C) - BSA Free
catalog :
NB300-543
quantity :
100 uL (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
34C
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 14
Reference
Broughton S, Hercus T, Hardy M, McClure B, Nero T, Dottore M, et al. Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody. Cell Rep. 2014;8:410-9 pubmed publisher
Koehl U, Brehm C, Huenecke S, Zimmermann S, Kloess S, Bremm M, et al. Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol. Front Oncol. 2013;3:118 pubmed publisher
Brehm C, Huenecke S, Quaiser A, Esser R, Bremm M, Kloess S, et al. IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study. PLoS ONE. 2011;6:e27351 pubmed publisher
Matsuo T, Ichimura K, Tanaka T, Morizane S, Iwatsuki K, Eguchi M, et al. Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm. J Clin Exp Hematop. 2011;51:49-55 pubmed
Rochereau N, Verrier B, Pin J, Genin C, Paul S. Phenotypic localization of distinct DC subsets in mouse Peyer Patch. Vaccine. 2011;29:3655-61 pubmed publisher
van de Laar L, van den Bosch A, van der Kooij S, Janssen H, Coffer P, van Kooten C, et al. A nonredundant role for canonical NF-?B in human myeloid dendritic cell development and function. J Immunol. 2010;185:7252-61 pubmed publisher
Bachmann M, Horn K, Rudloff I, Goren I, Holdener M, Christen U, et al. Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1. PLoS Pathog. 2010;6:e1001144 pubmed publisher
Tsoumakidou M, Tzanakis N, Papadaki H, Koutala H, Siafakas N. Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid. Immunol Cell Biol. 2006;84:267-73 pubmed
Treilleux I, Blay J, Bendriss Vermare N, Ray Coquard I, Bachelot T, Guastalla J, et al. Dendritic cell infiltration and prognosis of early stage breast cancer. Clin Cancer Res. 2004;10:7466-74 pubmed
Jordan T, Jiang H, Li H, DiMario J. Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-to-slow muscle fiber type transition. J Cell Sci. 2004;117:6175-83 pubmed
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, et al. Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 pubmed
Liu Z, Zhang J, Sharma M, Li P, Chen S, Wagenknecht T. Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus. Proc Natl Acad Sci U S A. 2001;98:6104-9 pubmed
Yamada K, Kanter E, Newatia A. Long-chain acylcarnitine induces Ca2+ efflux from the sarcoplasmic reticulum. J Cardiovasc Pharmacol. 2000;36:14-21 pubmed
Chan S, Mayne M, Holden C, Geiger J, Mattson M. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem. 2000;275:18195-200 pubmed
product information
master code :
NB300-543
SKU :
NB300-543
product name :
Ryanodine Receptor Antibody (34C) - BSA Free
unit size :
100 uL (also 0.025 ml)
description :
The Ryanodine Receptor Antibody (34C) - BSA Free from Novus is a mouse monoclonal antibody to Ryanodine Receptor. This antibody reacts with amphibian,bovine,canine,ferret,fish,human,mink,mouse,primate,rabbit,rat,sheep. The Ryanodine Receptor Antibody (34C) - BSA Free has been validated for the following applications: Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
Ryanodine Receptor
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
34C
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Partially purified chicken pectoral muscle ryanodine receptor.
isotype :
IgG1
purity :
Protein A purified
species :
Amphibian,Bovine,Canine,Ferret,Fish,Human,Mink,Mouse,Primate,Rabbit,Rat,Sheep
specificity :
This antibody detects ryanodine receptor Ryanodine Receptor-1 and Ryanodine Receptor-2 isoforms in amphibian, chicken, bovine, canine, fish, human, non-human primate, mouse, rabbit, mink, rat and sheep tissues
theoretical molecular weight :
565 kDa
gene symbol :
RYR1
accessionNumbers :
Q90984
applications :
Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
409 USD
alt names :
ARVC2, ARVD2, cardiac muscle ryanodine receptor-calcium release channel, cardiac-type ryanodine receptor, CCO, central core disease of muscle, islet-type ryanodine receptor, kidney-type ryanodine receptor, MHS, MHS1, PPP1R137, protein phosphatase 1, regulatory subunit 137, ryanodine receptor 1, ryanodine receptor 1 (skeletal), ryanodine receptor 2, ryanodine receptor 2 (cardiac), RYDR, RYR, RYR-1, RYR-2, sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, skeletal muscle ryanodine receptor, SKRR, type 1-like ryanodine receptor, type 2 ryanodine receptor, VTSIP
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.