product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GRP78/HSPA5 Antibody - BSA Free
catalog :
NB300-520
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 13
Reference
Veneri F, Prada V, Mastrangelo R, Ferri C, Nobbio L, Passalacqua M, et al. A novel mouse model of CMT1B identifies hyperglycosylation as a new pathogenetic mechanism. Hum Mol Genet. 2022;31:4255-4274 pubmed publisher
Bai Y, Treins C, Volpi V, Scapin C, Ferri C, Mastrangelo R, et al. Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice. Mol Neurobiol. 2022;59:4159-4178 pubmed publisher
Della Flora Nunes G, Wilson E, Hurley E, He B, O Malley B, Poitelon Y, et al. Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination. elife. 2021;10: pubmed publisher
Della Flora Nunes G, Wilson E, Marziali L, Hurley E, Silvestri N, He B, et al. Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells. Nat Commun. 2021;12:3285 pubmed publisher
Scapin C, Ferri C, Pettinato E, Bianchi F, Del Carro U, Feltri M, et al. Phosphorylation of eIF2α Promotes Schwann Cell Differentiation and Myelination in CMT1B Mice with Activated UPR. J Neurosci. 2020;40:8174-8187 pubmed publisher
Wang G, Xu J, Zhao J, Yin W, Liu D, Chen W, et al. Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice. Nat Commun. 2020;11:220 pubmed publisher
Yang X, Chung J, Rai U, Esumi N. Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo. PLoS ONE. 2018;13:e0191279 pubmed publisher
Xu M, Horrell J, Snitow M, Cui J, Gochnauer H, Syrett C, et al. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nat Commun. 2017;8:15397 pubmed publisher
Jin X, Li T, Zhang L, Ma J, Yu L, Li C, et al. Environmental Enrichment Improves Spatial Learning and Memory in Vascular Dementia Rats with Activation of Wnt/β-Catenin Signal Pathway. Med Sci Monit. 2017;23:207-215 pubmed
Chapados N, Boucher M. Liver metabolic disruption induced after a single exposure to PCB126 in rats. Environ Sci Pollut Res Int. 2017;24:1854-1861 pubmed publisher
Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, et al. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016;97:1-14 pubmed publisher
Musner N, Sidoli M, Zambroni D, Del Carro U, Ungaro D, D Antonio M, et al. Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy. ASN Neuro. 2016;8: pubmed publisher
Shin D, Feltri M, Wrabetz L. Altered Trafficking and Processing of GALC Mutants Correlates with Globoid Cell Leukodystrophy Severity. J Neurosci. 2016;36:1858-70 pubmed publisher
product information
master code :
NB300-520
SKU :
NB300-520
product name :
GRP78/HSPA5 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The GRP78/HSPA5 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to GRP78/HSPA5. This antibody reacts with human,mouse,primate (negative),rat. The GRP78/HSPA5 Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.
target :
GRP78/HSPA5
category :
Primary Antibodies
buffer :
PBS and 30% Glycerol
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to a C-terminal portion of rat GRP78 (within residues 600-654). [Uniprot: P06761]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Primate (Negative),Rat
theoretical molecular weight :
78 kDa
gene symbol :
HSPA5
applications :
Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western
USD :
409 USD
alt names :
78 kDa glucose-regulated protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, FLJ26106, GRP-78, GRP78BIP, Heat shock 70 kDa protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), Immunoglobulin heavy chain-binding protein, MIF2
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.