Protein Disulfide Isomerase/P4HB Antibody (RL90) | Novus Biologicals NB300-517 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Protein Disulfide Isomerase/P4HB Antibody (RL90)

catalog :

NB300-517

quantity :

100 uL

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RL90

reactivity :

African green monkey, human, mouse, rat, bovine, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 27

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1b immunocytochemistry; human; fig 1d	Zorin V, Pulin A, Eremin I, Korsakov I, Zorina A, Khromova N, et al. Myogenic potential of human alveolar mucosa derived cells. Cell Cycle. 2017;16:545-555 pubmed publisher
western blot; African green monkey; 1:2000; loading ...; fig 2k	Walsh M, Di Leo E, Okur I, Tarugi P, Hussain M. Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects. Biochim Biophys Acta. 2016;1861:1623-1633 pubmed publisher
	Voronkova M, Johnson B, Gandhi N, Koomen J, Patrick M, Shanthi Bhupathi S, et al. ERO1A levels are a prognostic indicator in EGFR mutated non small cell lung cancer. NPJ Precis Oncol. 2024;8:250 pubmed publisher
	Stempels F, Jiang M, Warner H, Moser M, Janssens M, Maassen S, et al. Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters. J Cell Biol. 2023;222: pubmed publisher
	Li Y, Kubo H, Yu D, Yang Y, Johnson J, Eaton D, et al. Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotype. Am J Physiol Heart Circ Physiol. 2023;324:H443-H460 pubmed publisher
	Lo M, Sharir A, Paul M, Torosyan H, Agnew C, Li A, et al. CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022;13:2407 pubmed publisher
	Kumar A, Welch N, Mishra S, Bellar A, Silva R, Li L, et al. Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence. JCI Insight. 2021;6: pubmed publisher
	Linders P, Gerretsen E, Ashikov A, Vals M, de Boer R, Revelo N, et al. Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5. Nat Commun. 2021;12:6227 pubmed publisher
	Beckmann L, Rolling C, Voigtländer M, Mäder J, Klingler F, Schulenkorf A, et al. Bacitracin and Rutin Regulate Tissue Factor Production in Inflammatory Monocytes and Acute Myeloid Leukemia Blasts. Cancers (Basel). 2021;13: pubmed publisher
	Paardekooper L, van Vroonhoven E, ter Beest M, van den Bogaart G. Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles. Int J Mol Sci. 2019;20: pubmed publisher
	Subramanian A, Capalbo A, Iyengar N, Rizzo R, Di Campli A, Di Martino R, et al. Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum. Cell. 2019;176:1461-1476.e23 pubmed publisher
	Liang D, Wu Y, Zhou L, Chen Y, Liu H, Xie D, et al. LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel. Int J Cardiol. 2019;275:120-128 pubmed publisher
	Sharma A, Alswillah T, Singh K, Chatterjee P, Willard B, Venere M, et al. USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination. Autophagy. 2018;14:1976-1990 pubmed publisher
	Dosoki H, Stegemann A, Taha M, Schnittler H, Luger T, Schröder K, et al. Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis. Exp Dermatol. 2017;26:73-81 pubmed publisher
	Pan S, Chen H, Correia C, Dai H, Witt T, Kleppe L, et al. Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate. PLoS ONE. 2014;9:e112986 pubmed publisher
	Langer F, Spath B, Fischer C, Stolz M, Ayuk F, Kroger N, et al. Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase. Blood. 2013;121:2324-35 pubmed publisher
	Hicks D, Makova N, Nalivaeva N, Turner A. Characterisation of acetylcholinesterase release from neuronal cells. Chem Biol Interact. 2013;203:302-8 pubmed publisher
	Elahi S, Niki T, Hirashima M, Horton H. Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection. Blood. 2012;119:4192-204 pubmed publisher
	Vallon M, Aubele P, Janssen K, Essler M. Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase. Biochem J. 2012;441:937-44 pubmed publisher
	Paule S, Li Y, Nie G. Cytoskeletal remodelling proteins identified in fetal-maternal interface in pregnant women and rhesus monkeys. J Mol Histol. 2011;42:161-6 pubmed publisher
	Paule S, Airey L, Li Y, Stephens A, Nie G. Proteomic approach identifies alterations in cytoskeletal remodelling proteins during decidualization of human endometrial stromal cells. J Proteome Res. 2010;9:5739-47 pubmed publisher
	Furmanski O, Gajavelli S, Lee J, Collado M, Jergova S, Sagen J. Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis. J Comp Neurol. 2009;515:56-71 pubmed publisher
	Kim S, Jun H, Mead P, Mansfield B, Chou J. Neutrophil stress and apoptosis underlie myeloid dysfunction in glycogen storage disease type Ib. Blood. 2008;111:5704-11 pubmed publisher
	Lahav J, Jurk K, Hess O, Barnes M, Farndale R, Luboshitz J, et al. Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange. Blood. 2002;100:2472-8 pubmed
	Bennett T, Edwards B, Sklar L, Rogelj S. Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes. J Immunol. 2000;164:4120-9 pubmed
	Tanaka S, Uehara T, Nomura Y. Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death. J Biol Chem. 2000;275:10388-93 pubmed
	Courageot J, Fenouillet E, Bastiani P, Miquelis R. Intracellular degradation of the HIV-1 envelope glycoprotein. Evidence for, and some characteristics of, an endoplasmic reticulum degradation pathway. Eur J Biochem. 1999;260:482-9 pubmed

product information

master code :

NB300-517

SKU :

NB300-517

product name :

Protein Disulfide Isomerase/P4HB Antibody (RL90)

unit size :

100 uL

description :

The Protein Disulfide Isomerase/P4HB Antibody (RL90) from Novus is a mouse monoclonal antibody to Protein Disulfide Isomerase/P4HB. This antibody reacts with bovine,hamster,human,monkey,mouse,porcine,primate,primate - macaca mulatta (rhesus macaque),rabbit,rat. The Protein Disulfide Isomerase/P4HB Antibody (RL90) has been validated for the following applications: IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunomicroscopy,Knockdown Validated.

target :

Protein Disulfide Isomerase/P4HB

category :

Primary Antibodies

buffer :

PBS with 1 mg/ml BSA

clonality :

Monoclonal

clone :

RL90

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Purified rat Protein Disulfide Isomerase/P4HB protein.

isotype :

IgG2a

purity :

Protein A purified

species :

Bovine,Hamster,Human,Monkey,Mouse,Porcine,Primate,Primate - Macaca mulatta (Rhesus Macaque),Rabbit,Rat

specificity :

NB300-517 detects Protein Disulfide Isomerase/P4HB from human, rat, porcine and mouse tissues as well as hamster cells

gene symbol :

P4HB

Antibody validation :

Knockout/Knockdown

applications :

IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunomicroscopy,Knockdown Validated

USD :

409 USD

alt names :

Cellular thyroid hormone-binding protein, collagen prolyl 4-hydroxylase beta, DSI, ERBA2L, GIT, glutathione-insulin transhydrogenase, P4Hbeta, p55, PDIA1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase-associated 1), PDIEC 5.3.4.1, PHDB, PO4DB, PO4HB, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide, PROHBprocollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase; thyroid hormone binding protein p55), Prolyl 4-hydroxylase subunit beta, prolyl 4-hydroxylase, beta polypeptide, protein disulfide isomerase family A, member 1, protein disulfide isomerase/oxidoreductase, protein disulfide isomerase-associated 1, protein disulfide-isomerase, protocollagen hydroxylase, thyroid hormone-binding protein p55

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage