product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNMT3B Antibody
catalog :
NB300-516
quantity :
100 ug (also 0.025 mg)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 4a
Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed publisher
Yang C, Deng L, Bao F, Jiang H, Zhang L. Sevoflurane with Low Concentration Decrease DNA Methylation on Chronic Obstructive Pulmonary Disease (COPD)-Related Gene Promoter in COPD Rat. COPD. 2023;20:348-356 pubmed publisher
Fuller A, Devine A, Murazzi I, Mason N, Weber K, Eisinger Mathason T. Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma. Cell Oncol (Dordr). 2022;45:1277-1295 pubmed publisher
Liu X, Cui H. The palliative effects of folic acid on retinal microvessels in diabetic retinopathy via regulating the metabolism of DNA methylation and hydroxymethylation. Bioengineered. 2021;12:10766-10774 pubmed publisher
Xie Z, Wang Q, Hu S. Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease. Bioengineered. 2021;12:5904-5915 pubmed publisher
Vohhodina J, Goehring L, Liu B, Kong Q, Botchkarev V, Huynh M, et al. BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage. Nat Commun. 2021;12:3542 pubmed publisher
Huang Z, Yu J, Cui W, Johnson B, Kim K, Pfeifer G. The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Sci Adv. 2021;7: pubmed publisher
Go S, Kurita H, Hatano M, Matsumoto K, Nogawa H, Fujimura M, et al. DNA methyltransferase- and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development. Arch Toxicol. 2021;95:1227-1239 pubmed publisher
Liu N, Zhang X, Jiang S, Shi J, Cui J, Liu X, et al. Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning. Neural Regen Res. 2020;15:2362-2368 pubmed publisher
Shiah S, Hsiao J, Chang H, Hsu Y, Wu G, Peng H, et al. MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer. J Biomed Sci. 2020;27:46 pubmed publisher
Aono S, Dennis J, He S, Wang W, Tao Y, Morrison E. Exploring Pleiotropic Functions of Canine β-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. Anat Rec (Hoboken). 2019;: pubmed publisher
Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I, et al. GADD45A binds R-loops and recruits TET1 to CpG island promoters. Nat Genet. 2019;51:217-223 pubmed publisher
Ponnaluri V, Esteve P, Ruse C, Pradhan S. S-adenosylhomocysteine Hydrolase Participates in DNA Methylation Inheritance. J Mol Biol. 2018;430:2051-2065 pubmed publisher
Karadag R, Bayram N, Oguztuzun S, Bayramlar H, Bozer B, Sımşek G, et al. An investigation of human beta-defensins and cathelicidin expression in patients with pterygium. Arq Bras Oftalmol. 2017;80:277-280 pubmed publisher
Zhong T, Men Y, Lu L, Geng T, Zhou J, Mitsuhashi A, et al. Metformin alters DNA methylation genome-wide via the H19/SAHH axis. Oncogene. 2017;36:2345-2354 pubmed publisher
Koerdt S, Steinstraesser L, Stoeckelhuber M, Wales C, Rohleder N, Babaryka G, et al. Radiotherapy for oral cancer decreases the cutaneous expression of host defence peptides. J Craniomaxillofac Surg. 2016;44:882-9 pubmed publisher
Dasgupta T, Nweze E, Yue H, Wang L, Jin J, Ghosh S, et al. Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53. Oncotarget. 2016;7:27430-44 pubmed publisher
Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, et al. H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase. Nat Commun. 2015;6:10221 pubmed publisher
Jeong K, Kim H. Neonatal capsaicin treatment in rats induces chronic hyperthermia resulting in infectious disease. Exp Ther Med. 2015;10:2417-2423 pubmed
Qian Y, Wang X, Gao Y, Duan N, Huang X, Sun F, et al. Cigarette Smoke Modulates NOD1 Signal Pathway and Human β Defensins Expression in Human Oral Mucosa. Cell Physiol Biochem. 2015;36:457-73 pubmed publisher
Levon J, Al Samadi A, Mackiewicz Z, Coer A, Trebse R, Waris E, et al. Human beta-defensin-3 producing cells in septic implant loosening. J Mater Sci Mater Med. 2015;26:98 pubmed publisher
Simon D, Radonjic Hösli S, Straumann A, Yousefi S, Simon H. Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy. 2015;70:443-52 pubmed publisher
product information
master code :
NB300-516
SKU :
NB300-516
product name :
DNMT3B Antibody
unit size :
100 ug (also 0.025 mg)
description :
The DNMT3B Antibody from Novus is a rabbit polyclonal antibody to DNMT3B. This antibody reacts with human,mouse,rat. The DNMT3B Antibody has been validated for the following applications: Chemotaxis,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western,Chromatin Immunoprecipitation (ChIP),Knockdown Validated.
target :
DNMT3B
category :
Primary Antibodies
buffer :
PBS with 1 mg/ml BSA
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide corresponding to the residues M(1) K G D S R H L N E E E G A(14) C of mouse DNMT3b
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
This detects DNA methyltransferase 3b (Dnmt3b) from human and mouse tissues and cells as well as recombinant human Dnmt3b
gene symbol :
DNMT3B
Antibody validation :
Biological Validation
accessionNumbers :
O88509
applications :
Chemotaxis,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western,Chromatin Immunoprecipitation (ChIP),Knockdown Validated
USD :
399 USD
alt names :
DNA (cytosine-5-)-methyltransferase 3 beta, DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, Dnmt3b, EC 2.1.1.37, ICF, M.HsaIIIB
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.