product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNMT3B Antibody
catalog :
NB300-516
quantity :
100 ug (also 0.025 mg)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 4a
Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed publisher
Huang X, Balmer S, Lyu C, Xiang Y, Malik V, Wang H, et al. ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1. Dev Cell. 2024;59:465-481.e6 pubmed publisher
Yang C, Deng L, Bao F, Jiang H, Zhang L. Sevoflurane with Low Concentration Decrease DNA Methylation on Chronic Obstructive Pulmonary Disease (COPD)-Related Gene Promoter in COPD Rat. COPD. 2023;20:348-356 pubmed publisher
Fuller A, Devine A, Murazzi I, Mason N, Weber K, Eisinger Mathason T. Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma. Cell Oncol (Dordr). 2022;45:1277-1295 pubmed publisher
Liu X, Cui H. The palliative effects of folic acid on retinal microvessels in diabetic retinopathy via regulating the metabolism of DNA methylation and hydroxymethylation. Bioengineered. 2021;12:10766-10774 pubmed publisher
Xie Z, Wang Q, Hu S. Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease. Bioengineered. 2021;12:5904-5915 pubmed publisher
Vohhodina J, Goehring L, Liu B, Kong Q, Botchkarev V, Huynh M, et al. BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage. Nat Commun. 2021;12:3542 pubmed publisher
Huang Z, Yu J, Cui W, Johnson B, Kim K, Pfeifer G. The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Sci Adv. 2021;7: pubmed publisher
Go S, Kurita H, Hatano M, Matsumoto K, Nogawa H, Fujimura M, et al. DNA methyltransferase- and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development. Arch Toxicol. 2021;95:1227-1239 pubmed publisher
Liu N, Zhang X, Jiang S, Shi J, Cui J, Liu X, et al. Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning. Neural Regen Res. 2020;15:2362-2368 pubmed publisher
Shiah S, Hsiao J, Chang H, Hsu Y, Wu G, Peng H, et al. MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer. J Biomed Sci. 2020;27:46 pubmed publisher
Aono S, Dennis J, He S, Wang W, Tao Y, Morrison E. Exploring Pleiotropic Functions of Canine β-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. Anat Rec (Hoboken). 2019;: pubmed publisher
Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I, et al. GADD45A binds R-loops and recruits TET1 to CpG island promoters. Nat Genet. 2019;51:217-223 pubmed publisher
Ponnaluri V, Esteve P, Ruse C, Pradhan S. S-adenosylhomocysteine Hydrolase Participates in DNA Methylation Inheritance. J Mol Biol. 2018;430:2051-2065 pubmed publisher
Karadag R, Bayram N, Oguztuzun S, Bayramlar H, Bozer B, Sımşek G, et al. An investigation of human beta-defensins and cathelicidin expression in patients with pterygium. Arq Bras Oftalmol. 2017;80:277-280 pubmed publisher
Zhong T, Men Y, Lu L, Geng T, Zhou J, Mitsuhashi A, et al. Metformin alters DNA methylation genome-wide via the H19/SAHH axis. Oncogene. 2017;36:2345-2354 pubmed publisher
Koerdt S, Steinstraesser L, Stoeckelhuber M, Wales C, Rohleder N, Babaryka G, et al. Radiotherapy for oral cancer decreases the cutaneous expression of host defence peptides. J Craniomaxillofac Surg. 2016;44:882-9 pubmed publisher
Dasgupta T, Nweze E, Yue H, Wang L, Jin J, Ghosh S, et al. Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53. Oncotarget. 2016;7:27430-44 pubmed publisher
Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, et al. H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase. Nat Commun. 2015;6:10221 pubmed publisher
Jeong K, Kim H. Neonatal capsaicin treatment in rats induces chronic hyperthermia resulting in infectious disease. Exp Ther Med. 2015;10:2417-2423 pubmed
Qian Y, Wang X, Gao Y, Duan N, Huang X, Sun F, et al. Cigarette Smoke Modulates NOD1 Signal Pathway and Human β Defensins Expression in Human Oral Mucosa. Cell Physiol Biochem. 2015;36:457-73 pubmed publisher
Levon J, Al Samadi A, Mackiewicz Z, Coer A, Trebse R, Waris E, et al. Human beta-defensin-3 producing cells in septic implant loosening. J Mater Sci Mater Med. 2015;26:98 pubmed publisher
Simon D, Radonjic Hösli S, Straumann A, Yousefi S, Simon H. Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy. 2015;70:443-52 pubmed publisher
product information
brand :
Novus
catalog number base :
NB300-516
SKU :
NB300-516
product name :
DNMT3B Antibody
units size :
100 ug (also 0.025 mg)
description :
The DNMT3B Antibody from Novus is a rabbit polyclonal antibody to DNMT3B. This antibody reacts with human,mouse,rat. The DNMT3B Antibody has been validated for the following applications: Chemotaxis,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Chromatin Immunoprecipitation (ChIP),Knockdown Validated.
target :
DNMT3B
category :
Primary Antibodies
buffer :
PBS with 1 mg/ml BSA
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide corresponding to the residues M(1) K G D S R H L N E E E G A(14) C of mouse DNMT3b
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
DNMT3B
review stars :
4
Antibody validation :
Biological Validation
top caption :
Western Blot: DNMT3B Antibody [NB300-516]
accessionNumbers :
O88509
applications :
Chemotaxis,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Chromatin Immunoprecipitation (ChIP),Knockdown Validated
USD :
399 USD
alt names :
DNA (cytosine-5-)-methyltransferase 3 beta, DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, Dnmt3b, EC 2.1.1.37, ICF, M.HsaIIIB
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.