product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CFTR Antibody (CF3)
catalog :
NB300-511
quantity :
100 uL
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CF3
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 13
Reference
Mizoguchi M, Takemori H, Furukawa S, Ito M, Asai M, Morino H, et al. Increased expression of glucagon-like peptide-1 and cystic fibrosis transmembrane conductance regulator in the ileum and colon in mouse treated with metformin. Endocr J. 2023;70:149-159 pubmed publisher
Lu L, Pan N, Huang Z, Wang J, Tang Y, Sun H, et al. CFTR Suppresses Neointimal Formation Through Attenuating Proliferation and Migration of Aortic Smooth Muscle Cells. J Cardiovasc Pharmacol. 2022;79:914-924 pubmed publisher
Di Fulvio M, Bogdani M, Velasco M, McMillen T, Ridaura C, Kelly L, et al. Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet. PLoS ONE. 2020;15:e0242749 pubmed publisher
Marozkina N, Bosch J, Cotton C, Smith L, Seckler J, Zaman K, et al. Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium. Am J Physiol Lung Cell Mol Physiol. 2019;317:L247-L258 pubmed publisher
Ye R, Onodera T, Blanchard P, Kusminski C, Esser V, Brekken R, et al. β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis. Am J Pathol. 2019;189:813-825 pubmed publisher
Romani L, Oikonomou V, Moretti S, Iannitti R, D Adamo M, Villella V, et al. Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis. Nat Med. 2017;23:590-600 pubmed publisher
Meissner A, Yang J, Kroetsch J, Sauvé M, Dax H, Momen A, et al. Tumor necrosis factor-?-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure. Circulation. 2012;125:2739-50 pubmed publisher
Rottner M, Kunzelmann C, Mergey M, Freyssinet J, Martinez M. Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells. FASEB J. 2007;21:2939-48 pubmed
Kulka M, Dery R, Nahirney D, Duszyk M, Befus A. Differential regulation of cystic fibrosis transmembrane conductance regulator by interferon gamma in mast cells and epithelial cells. J Pharmacol Exp Ther. 2005;315:563-70 pubmed
Benlloch M, Ortega A, Ferrer P, Segarra R, Obrador E, Asensi M, et al. Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity. J Biol Chem. 2005;280:6950-9 pubmed
Dalby Payne J, O Loughlin E, Gunning P. Polarization of specific tropomyosin isoforms in gastrointestinal epithelial cells and their impact on CFTR at the apical surface. Mol Biol Cell. 2003;14:4365-75 pubmed
Laverty G, McWilliams C, Sheldon A, Arnason S. PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture. Am J Physiol Renal Physiol. 2003;284:F987-95 pubmed
Kulka M, Gilchrist M, Duszyk M, Befus A. Expression and functional characterization of CFTR in mast cells. J Leukoc Biol. 2002;71:54-64 pubmed
product information
master code :
NB300-511
SKU :
NB300-511
product name :
CFTR Antibody (CF3)
unit size :
100 uL
description :
The CFTR Antibody (CF3) from Novus is a mouse monoclonal antibody to CFTR. This antibody reacts with avian - chicken,chicken,golden syrian hamster,human,mouse,rat. The CFTR Antibody (CF3) has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Block/Neutralize.
target :
CFTR
category :
Primary Antibodies
buffer :
Ascites
clonality :
Monoclonal
clone :
CF3
conjugate :
Unconjugated
host :
Mouse
immunogen :
Synthetic Peptide: G(103) R I I A S Y D P D N K E E R(117)
isotype :
IgM
purity :
Unpurified
species :
Avian - Chicken,Chicken,Golden Syrian Hamster,Human,Mouse,Rat
specificity :
CFTR (CF3)
theoretical molecular weight :
168 kDa
gene symbol :
CFTR
accessionNumbers :
P13569
applications :
Western Blot,IF/IHC,Flow Cytometry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Block/Neutralize
USD :
479 USD
alt names :
ABC35, ABCC7CF, ATP-binding cassette sub-family C member 7, ATP-binding cassette transporter sub-family C member 7, cAMP-dependent chloride channel, CFTR/MRP, Channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator, cystic fibrosis transmembrane conductance regulator (ATP-binding cassettesub-family C, member 7), cystic fibrosis transmembrane conductance regulator, ATP-binding cassette(sub-family C, member 7), dJ760C5.1, EC 3.6.3, MRP7EC 3.6.3.49, TNR-CFTR
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.