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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NFATC2/NFAT1 Antibody (25A10.D6.D2) - BSA Free
catalog :
NB300-504
quantity :
100 ug (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
25A10.D6.D2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:100; fig 3f
Liu J, Han Z, Han Z, He Z. Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension. Exp Ther Med. 2016;11:467-475 pubmed
Wang M, Zhao M, Xu S, Zheng Z, Zhang J, Pan W, et al. TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats. Biochem Pharmacol. 2023;214:115671 pubmed publisher
Zhu L, Zhou X, Gu M, Kim J, Li Y, Ko C, et al. Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer. Nat Cell Biol. 2022;24:1165-1176 pubmed publisher
Li H, Wu Y, Tseng T, Chao S, Lin H, Chen H. Inhibition of miR-155 potentially protects against lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway. Am J Physiol Cell Physiol. 2020;319:C1070-C1081 pubmed publisher
Li Z, Jiang L, Chew S, Hirayama T, Sekido Y, Toyokuni S. Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia. Redox Biol. 2019;26:101297 pubmed publisher
Song S, Carr S, McDermott K, Rodriguez M, Babicheva A, Balistrieri A, et al. STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension. Hypertension. 2018;71:518-529 pubmed publisher
Kelly N, Varga J, Specker E, Romeo C, Coomber B, Uniacke J. Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion. Oncogene. 2018;37:651-662 pubmed publisher
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed publisher
Jin H, Wang C, Jin G, Ruan H, Gu D, Wei L, et al. Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1. Gastroenterology. 2017;153:799-811.e33 pubmed publisher
Federici C, Lugini L, Marino M, Carta F, Iessi E, Azzarito T, et al. Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. J Enzyme Inhib Med Chem. 2016;31:119-125 pubmed
Cotroneo E, Ashek A, Wang L, Wharton J, Dubois O, Bozorgi S, et al. Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. Circ Res. 2015;116:1680-90 pubmed publisher
Cai C, Alshehri A, Choksi R, Pestronk A. Regional ischemic immune myopathy: a paraneoplastic dermatomyopathy. J Neuropathol Exp Neurol. 2014;73:1126-33 pubmed publisher
Iampietro M, Morissette G, Gravel A, Flamand L. Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein. J Virol. 2014;88:12452-63 pubmed publisher
Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, et al. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1? stability and MGMT expression. Cell Death Dis. 2012;3:e412 pubmed publisher
Landry J, Banerjee S, Taylor B, Aplan P, Singer A, Wu C. Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev. 2011;25:275-86 pubmed publisher
Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, et al. Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1. Hepatology. 2011;53:628-39 pubmed publisher
Barlic J, McDermott D, Merrell M, Gonzales J, Via L, Murphy P. Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms. J Biol Chem. 2004;279:48520-34 pubmed
product information
master code :
NB300-504
SKU :
NB300-504
product name :
NFATC2/NFAT1 Antibody (25A10.D6.D2) - BSA Free
unit size :
100 ug (also 0.025 mg)
description :
The NFATC2/NFAT1 Antibody (25A10.D6.D2) - BSA Free from Novus is a mouse monoclonal antibody to NFATC2/NFAT1. This antibody reacts with human,mouse,rat. The NFATC2/NFAT1 Antibody (25A10.D6.D2) - BSA Free has been validated for the following applications: Chemotaxis,IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Gel Super Shift Assays,Sandwich ELISA,Chromatin Immunoprecipitation (ChIP).
target :
NFATC2/NFAT1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
25A10.D6.D2
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Synthetic peptide corresponding to residues A(51) I S S P S G L A Y P D D V L D Y G L(69) of mouse NFATc2-A, B and C isoforms.
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
specificity :
Detects nuclear factor of activated T-cells (NFAT)
theoretical molecular weight :
140 kDa
gene symbol :
NFATC2
applications :
Chemotaxis,IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Gel Super Shift Assays,Sandwich ELISA,Chromatin Immunoprecipitation (ChIP)
USD :
409 USD
alt names :
NFAT pre-existing subunit, NFAT transcription complex, preexisting component, NFAT1nuclear factor of activated T-cells, cytoplasmic 2, NFATc2, NF-ATc2, NFATp, NF-ATp, NFATPnuclear factor of activated T-cells, preexisting component, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2, preexisting nuclear factor of activated T-cells 2, T cell transcription factor NFAT1, T-cell transcription factor NFAT1
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.