product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Park7/DJ-1 Antibody - BSA Free
catalog :
NB300-270
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
ESEE122
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 82
Reference
Bhattacharyya S, Sturgis J, Maminishkis A, Miller S, Bonilha V. Oxidation of DJ-1 Cysteines in Retinal Pigment Epithelium Function. Int J Mol Sci. 2022;23: pubmed publisher
Gharbi N, Røise D, Førre J, Edson A, Hushagen H, Tronci V, et al. Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina. Antioxidants (Basel). 2021;10: pubmed publisher
Wolk A, Upadhyay M, Ali M, Suh J, Stoehr H, Bonilha V, et al. The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration. Redox Biol. 2020;37:101681 pubmed publisher
Upadhyay M, Milliner C, Bell B, Bonilha V. Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1. Redox Biol. 2020;:101623 pubmed publisher
Somasekharan S, Zhang F, Saxena N, Huang J, Kuo I, Low C, et al. G3BP1-linked mRNA partitioning supports selective protein synthesis in response to oxidative stress. Nucleic Acids Res. 2020;48:6855-6873 pubmed publisher
Riou C, Brionne A, Cordeiro L, Harichaux G, Gargaros A, Labas V, et al. Avian uterine fluid proteome: Exosomes and biological processes potentially involved in sperm survival. Mol Reprod Dev. 2020;87:454-470 pubmed publisher
Yoo S, Yoo J, Kim H, Baik T, Lee J, Woo R. Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl2-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells. Int Neurourol J. 2019;23:S111-118 pubmed publisher
Edson A, Hushagen H, Frøyset A, Elda I, Khan E, Di Stefano A, et al. Dysregulation in the Brain Protein Profile of Zebrafish Lacking the Parkinson's Disease-Related Protein DJ-1. Mol Neurobiol. 2019;: pubmed publisher
Otsuka S, Sakakima H, Terashi T, Takada S, Nakanishi K, Kikuchi K. Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats. Brain Struct Funct. 2019;224:727-738 pubmed publisher
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed publisher
Daskalakis K, Kaltsas G, Oberg K, Tsolakis A. Lung Carcinoids: Long-Term Surgical Results and the Lack of Prognostic Value of Somatostatin Receptors and Other Novel Immunohistochemical Markers. Neuroendocrinology. 2018;107:355-365 pubmed publisher
Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
Hubbard W, Lashof Sullivan M, Greenberg S, Norris C, Eck J, Lavik E, et al. Hemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model. Sci Rep. 2018;8:10622 pubmed publisher
Kanakis G, Grimelius L, Papaioannou D, Kaltsas G, Tsolakis A. Can insulin-like growth factor 1 (IGF-1), IGF-1 receptor connective tissue growth factor and Ki-67 labelling index have a prognostic role in pulmonary carcinoids?. Oncotarget. 2018;9:22653-22664 pubmed publisher
Rossow L, Veitl S, Vorlova S, Wax J, Kuhn A, Maltzahn V, et al. LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy. Oncogene. 2018;37:4921-4940 pubmed publisher
Jayabal P, Houghton P, Shiio Y. EWS-FLI-1 creates a cell surface microenvironment conducive to IGF signaling by inducing pappalysin-1. Genes Cancer. 2017;8:762-770 pubmed publisher
Toblli J, Cao G, Giani J, Dominici F, Angerosa M. Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds. Drug Des Devel Ther. 2017;11:2251-2263 pubmed publisher
Porrini V, Mota M, Parrella E, Bellucci A, Benarese M, Faggi L, et al. Mild Inflammatory Profile without Gliosis in the c-Rel Deficient Mouse Modeling a Late-Onset Parkinsonism. Front Aging Neurosci. 2017;9:229 pubmed publisher
Gustafsson H, Kale A, Daşu A, Lund A, Edqvist P, Roberg K. EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model. Cell Biochem Biophys. 2017;75:299-309 pubmed publisher
McKelvie P, de Leval L, Edlefsen K, Ko Y, Aberman Z, Kovach A, et al. Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation. Am J Surg Pathol. 2017;41:299-312 pubmed publisher
Huang T, Chung S, Chua S, Chai H, Sheu J, Chen Y, et al. Effect of early administration of lower dose versus high dose of fresh mitochondria on reducing monocrotaline-induced pulmonary artery hypertension in rat. Am J Transl Res. 2016;8:5151-5168 pubmed
Hjelmgren O, Gellerman K, Kjelldahl J, Lindahl P, Bergström G. Increased Vascularization in the Vulnerable Upstream Regions of Both Early and Advanced Human Carotid Atherosclerosis. PLoS ONE. 2016;11:e0166918 pubmed publisher
Siebenmann C, Keramidas M, Rundqvist H, Mijwel S, Cowburn A, Johnson R, et al. Cutaneous exposure to hypoxia does not affect skin perfusion in humans. Acta Physiol (Oxf). 2017;220:361-369 pubmed publisher
Cahill L, Gazdzinski L, Tsui A, Zhou Y, Portnoy S, Liu E, et al. Functional and anatomical evidence of cerebral tissue hypoxia in young sickle cell anemia mice. J Cereb Blood Flow Metab. 2017;37:994-1005 pubmed publisher
Koh J, Jang J, Keam B, Kim S, Kim M, Go H, et al. EML4-ALK enhances programmed cell death-ligand 1 expression in pulmonary adenocarcinoma via hypoxia-inducible factor (HIF)-1α and STAT3. Oncoimmunology. 2016;5:e1108514 pubmed
Miller A, Deal D, Green J, Houle T, Brown W, Thore C, et al. Use of the Reamer/Irrigator/Aspirator Decreases Carotid and Cranial Embolic Events in a Canine Model. J Bone Joint Surg Am. 2016;98:658-64 pubmed publisher
Fan Y, Li H, Ma X, Gao Y, Bao X, Du Q, et al. Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α. Oncotarget. 2016;7:18280-94 pubmed publisher
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher
Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, et al. Carbonic Anhydrase XII as an Independent Prognostic Factor in Advanced Esophageal Squamous Cell Carcinoma. J Cancer. 2015;6:922-9 pubmed publisher
Bonilha V, Bell B, Rayborn M, Yang X, Kaul C, Grossman G, et al. Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice. Exp Eye Res. 2015;139:22-36 pubmed publisher
Deng J, Zhao F, Yu X, Li D, Zhao Y. Identification of the Protective Role of DJ-1 in Hypoglycemic Astrocyte Injury Using Proteomics. J Proteome Res. 2015;14:2839-48 pubmed publisher
Shankar G, Taylor Weiner A, Lelic N, Jones R, Kim J, FRANCIS J, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun. 2014;2:167 pubmed publisher
Shi X, Guo L, Seedial S, Si Y, Wang B, Takayama T, et al. TGF-?/Smad3 inhibit vascular smooth muscle cell apoptosis through an autocrine signaling mechanism involving VEGF-A. Cell Death Dis. 2014;5:e1317 pubmed publisher
Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed publisher
Vasuri F, Fittipaldi S, Abualhin M, DeGiovanni A, Gargiulo M, Stella A, et al. Biochemical and immunomorphological evaluation of hepatocyte growth factor and c-Met pathway in patients with critical limb ischemia. Eur J Vasc Endovasc Surg. 2014;48:430-7 pubmed publisher
Schaible E, Windschügl J, Bobkiewicz W, Kaburov Y, Dangel L, Kramer T, et al. 2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1? response after traumatic brain injury in mice. J Neurochem. 2014;129:940-54 pubmed publisher
Stenvold H, Donnem T, Andersen S, Al Saad S, Valkov A, Pedersen M, et al. High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome. BMC Clin Pathol. 2014;14:9 pubmed publisher
Tajdini M, Mirbagheri S, Nikooie R, Ostovaneh M, Ghoreyshi Hefzabad S, Garg S, et al. Tissue hypoxia in pathogenesis of ulcerative colitis: should we change all our beliefs?. Scand J Gastroenterol. 2013;48:1487-8 pubmed publisher
Kim B, Cho H, Chung J, Conway C, Ylaya K, Kim J, et al. Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry. J Transl Med. 2013;11:185 pubmed publisher
Liu M, Guo X, Wang S, Jin M, Wang Y, Li J, et al. BOLD-MRI of breast invasive ductal carcinoma: correlation of R2* value and the expression of HIF-1?. Eur Radiol. 2013;23:3221-7 pubmed publisher
Scott E, Boursiquot N, Beltran W, Dubielzig R. Early histopathologic changes in the retina and optic nerve in canine primary angle-closure glaucoma. Vet Ophthalmol. 2013;16 Suppl 1:79-86 pubmed publisher
Finger E, Cheng C, Williams T, Rankin E, Bedogni B, Tachiki L, et al. CTGF is a therapeutic target for metastatic melanoma. Oncogene. 2014;33:1093-100 pubmed publisher
Hu T, Beattie W, Mazer C, Leong Poi H, Fujii H, Wilson D, et al. Treatment with a highly selective ?? antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats. Anesth Analg. 2013;116:649-62 pubmed publisher
Rahimi A, Wilson D, Saylor D, Stelow E, Thomas C, Reibel J, et al. p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. Int J Otolaryngol. 2012;2012:685951 pubmed publisher
Smeland E, Kilvaer T, Sorbye S, Valkov A, Andersen S, Bremnes R, et al. Prognostic impacts of hypoxic markers in soft tissue sarcoma. Sarcoma. 2012;2012:541650 pubmed publisher
Rezvani H, Ali N, Serrano Sanchez M, Dubus P, Varon C, Ged C, et al. Loss of epidermal hypoxia-inducible factor-1? accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci. 2011;124:4172-83 pubmed publisher
Namas R, Metukuri M, Dhupar R, Velosa C, Jefferson B, Myer E, et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1? in mouse hepatocytes. Shock. 2011;36:196-202 pubmed publisher
Eckert A, Lautner M, Schutze A, Taubert H, Schubert J, Bilkenroth U. Coexpression of hypoxia-inducible factor-1? and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients. Histopathology. 2011;58:1136-47 pubmed publisher
Halterman M. An improved method for the study of apoptosis-related genes using the tet-on system. J Biomol Screen. 2011;16:332-7 pubmed publisher
Andersen S, Eilertsen M, Donnem T, Al Shibli K, Al Saad S, Busund L, et al. Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer. 2011;72:294-302 pubmed publisher
Park S, Ha S, Cho H, Chung D, Kim N, Hong J, et al. Prognostic implications of hypoxia-inducible factor-1? in epidermal growth factor receptor-negative non-small cell lung cancer. Lung Cancer. 2011;72:100-7 pubmed publisher
Bennecke M, Kriegl L, Bajbouj M, Retzlaff K, Robine S, Jung A, et al. Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis. Cancer Cell. 2010;18:135-46 pubmed publisher
Lerman O, Greives M, Singh S, Thanik V, Chang C, Seiser N, et al. Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction. Blood. 2010;116:3669-76 pubmed publisher
Arvidsson Y, Bergström A, Arvidsson L, Kristiansson E, Ahlman H, Nilsson O. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr Relat Cancer. 2010;17:303-16 pubmed publisher
Lei Z, Li B, Yang Z, Fang H, Zhang G, Feng Z, et al. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS ONE. 2009;4:e7629 pubmed publisher
Ragoonanan T, Beattie W, Mazer C, Tsui A, Leong Poi H, Wilson D, et al. Metoprolol reduces cerebral tissue oxygen tension after acute hemodilution in rats. Anesthesiology. 2009;111:988-1000 pubmed publisher
Rasheed S, Harris A, Tekkis P, Turley H, Silver A, McDonald P, et al. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br J Cancer. 2009;100:1666-73 pubmed publisher
Pina Oviedo S, Khalili K, Del Valle L. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol. 2009;118:235-47 pubmed publisher
Dorević G, Matusan Ilijas K, Babarović E, Hadzisejdic I, Grahovac M, Grahovac B, et al. Hypoxia inducible factor-1alpha correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cell renal cell carcinoma. J Exp Clin Cancer Res. 2009;28:40 pubmed publisher
Gomes E, Rodrigues M, Phadke A, Butcher L, Starling C, Chen S, et al. Antitumor activity of an oncolytic adenoviral-CD40 ligand (CD154) transgene construct in human breast cancer cells. Clin Cancer Res. 2009;15:1317-25 pubmed publisher
Viola R, Provenzale J, Li F, Li C, Yuan H, Tashjian J, et al. In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy. AJR Am J Roentgenol. 2008;191:1779-84 pubmed publisher
Sutton T, Wilkinson J, Mang H, Knipe N, Plotkin Z, Hosein M, et al. p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2008;295:F1666-77 pubmed publisher
Reiser Erkan C, Erkan M, Pan Z, Bekasi S, Giese N, Streit S, et al. Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2008;7:1352-9 pubmed
Shimogai R, Kigawa J, Itamochi H, Iba T, Kanamori Y, Oishi T, et al. Expression of hypoxia-inducible factor 1alpha gene affects the outcome in patients with ovarian cancer. Int J Gynecol Cancer. 2008;18:499-505 pubmed publisher
Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, et al. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 2008;453:1117-21 pubmed publisher
Hartmann H, Eltzschig H, Wurz H, Hantke K, Rakin A, Yazdi A, et al. Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. Gastroenterology. 2008;134:756-67 pubmed publisher
Kubo T, Sugita T, Shimose S, Matsuo T, Arihiro K, Ochi M. Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br. 2008;90:364-70 pubmed publisher
Piovan E, Tosello V, Indraccolo S, Masiero M, Persano L, Esposito G, et al. Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis. Cancer Res. 2007;67:8605-14 pubmed
Monsef N, Helczynski L, Lundwall A, Påhlman S. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate. 2007;67:1219-29 pubmed
Lee S, Garner E, Welch W, Berkowitz R, Mok S. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma. Gynecol Oncol. 2007;106:311-7 pubmed
Kyriacou H, Steen K, Raza A, Arman M, Warimwe G, Bull P, et al. In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate. Antimicrob Agents Chemother. 2007;51:1321-6 pubmed
Choke E, Cockerill G, Dawson J, Chung Y, Griffiths J, Wilson R, et al. Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate. Ann N Y Acad Sci. 2006;1085:306-10 pubmed
Khan Z, Michalopoulos G, Stolz D. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am J Pathol. 2006;169:1251-69 pubmed
Carroll P, Kenerson H, Yeung R, Lagunoff M. Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J Virol. 2006;80:10802-12 pubmed
Ardyanto T, Osaki M, Tokuyasu N, Nagahama Y, Ito H. CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. Int J Oncol. 2006;29:549-55 pubmed
Lidgren A, Hedberg Y, Grankvist K, Rasmuson T, Bergh A, Ljungberg B. Hypoxia-inducible factor 1alpha expression in renal cell carcinoma analyzed by tissue microarray. Eur Urol. 2006;50:1272-7 pubmed
Hirami Y, Aoe M, Tsukuda K, Hara F, Otani Y, Koshimune R, et al. Relation of epidermal growth factor receptor, phosphorylated-Akt, and hypoxia-inducible factor-1alpha in non-small cell lung cancers. Cancer Lett. 2004;214:157-64 pubmed
Abbate A, Santini D, Biondi Zoccai G, Scarpa S, Vasaturo F, Liuzzo G, et al. Cyclo-oxygenase-2 (COX-2) expression at the site of recent myocardial infarction: friend or foe?. Heart. 2004;90:440-3 pubmed
Beasley N, Leek R, Alam M, Turley H, Cox G, Gatter K, et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002;62:2493-7 pubmed
Giatromanolaki A, Koukourakis M, Sivridis E, Pastorek J, Wykoff C, Gatter K, et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001;61:7992-8 pubmed
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Talks K, Turley H, Gatter K, Maxwell P, Pugh C, Ratcliffe P, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157:411-21 pubmed
product information
master code :
NB300-270
SKU :
NB300-270
product name :
Park7/DJ-1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Park7/DJ-1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Park7/DJ-1. This antibody reacts with avian - chicken,chicken,human,mouse,rat. The Park7/DJ-1 Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Western Blot,Flow Cytometry,Immunohistochemistry-Paraffin,In vitro assay,Simple Western.
target :
Park7/DJ-1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1). [UniProt# Q99497]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Avian - Chicken,Chicken,Human,Mouse,Rat
theoretical molecular weight :
25 kDa
gene symbol :
PARK7
Antibody validation :
Biological Validation
accessionNumbers :
Q99497
applications :
Immunohistochemistry,Western Blot,Flow Cytometry,Immunoprecipitation,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,In vitro assay,Simple Western
USD :
409 USD
alt names :
DJ-1, DJ1FLJ34360, EC 3.4, FLJ27376, FLJ92274, Oncogene DJ1, Parkinson disease (autosomal recessive, early onset) 7, Parkinson disease protein 7, protein DJ-1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.