| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; mouse; 2.5 ug/ml; fig 12
| Mitrea D, Cika J, Guy C, Ban D, Banerjee P, Stanley C, et al. Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA. elife. 2016;5: pubmed publisher |
- immunohistochemistry; fruit fly
| Zaballos M, Cantero W, Azpiazu N. The TALE transcription factor homothorax functions to assemble heterochromatin during Drosophila embryogenesis. PLoS ONE. 2015;10:e0120662 pubmed publisher |
- immunocytochemistry; human
| Zillner K, Filarsky M, Rachow K, Weinberger M, Längst G, Nemeth A. Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Res. 2013;41:5251-62 pubmed publisher |
- immunohistochemistry - paraffin section; human
- western blot; human
| Su H, Xu T, Ganapathy S, Shadfan M, Long M, Huang T, et al. Elevated snoRNA biogenesis is essential in breast cancer. Oncogene. 2014;33:1348-58 pubmed publisher |
- immunohistochemistry - frozen section; mouse
- immunocytochemistry; mouse
- immunohistochemistry; mouse
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| Hao Q, Liu M, Daulatabad S, Gaffari S, Song Y, Srivastava R, et al. Monoallelically expressed noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression. elife. 2024;13: pubmed publisher |
| Klump B, Perez G, Patrick E, Adams Boone K, Cohen S, Han L, et al. TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly. Cell Rep. 2023;42:112577 pubmed publisher |
| Papandreou M, Konstantinidis G, Tavernarakis N. Nucleophagy delays aging and preserves germline immortality. Nat Aging. 2023;3:34-46 pubmed publisher |
| Palikaras K, Mari M, Ploumi C, Princz A, Filippidis G, Tavernarakis N. Age-dependent nuclear lipid droplet deposition is a cellular hallmark of aging in Caenorhabditis elegans. Aging Cell. 2023;22:e13788 pubmed publisher |
| Loganathan R, Levings D, Kim J, Wells M, Chiu H, Wu Y, et al. Ribbon boosts ribosomal protein gene expression to coordinate organ form and function. J Cell Biol. 2022;221: pubmed publisher |
| Hibino E, Ichiyama Y, Tsukamura A, Senju Y, Morimune T, Ohji M, et al. Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacity. BMC Biol. 2022;20:42 pubmed publisher |
| Wu T, Nance J, Chu F, Fazzio T. Characterization of R-Loop-Interacting Proteins in Embryonic Stem Cells Reveals Roles in rRNA Processing and Gene Expression. Mol Cell Proteomics. 2021;20:100142 pubmed publisher |
| Procida T, Friedrich T, Jack A, Peritore M, Bönisch C, Eberl H, et al. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions. Int J Mol Sci. 2021;22: pubmed publisher |
| Sural S, Liang C, Wang F, Ching T, Hsu A. HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sci Adv. 2020;6: pubmed publisher |
| Mitrousis N, Hacibekiroglu S, Ho M, Sauve Y, Nagy A, van der Kooy D, et al. Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration. Biomaterials. 2020;257:120233 pubmed publisher |
| Begik O, Lucas M, Liu H, Ramírez J, Mattick J, Novoa E. Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures. Genome Biol. 2020;21:97 pubmed publisher |
| Song J, Han D, Lee H, Kim D, Cho J, Park J, et al. A Comprehensive Proteomic and Phosphoproteomic Analysis of Retinal Pigment Epithelium Reveals Multiple Pathway Alterations in Response to the Inflammatory Stimuli. Int J Mol Sci. 2020;21: pubmed publisher |
| Hsiung K, Liu K, Tsai T, Yoshina S, Mitani S, Chin Ming Tan B, et al. Defects in CISD-1, a mitochondrial iron-sulfur protein, lower glucose level and ATP production in Caenorhabditis elegans. Biomed J. 2020;43:32-43 pubmed publisher |
| Lehmann G, Hanke Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, et al. Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. J Exp Med. 2020;217: pubmed publisher |
| Yang C, Shani S, Tahiri H, Ortiz C, Gu M, Lavoie J, et al. Extracellular microparticles exacerbate oxidative damage to retinal pigment epithelial cells. Exp Cell Res. 2020;390:111957 pubmed publisher |
| Wright C, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, et al. Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Proc Natl Acad Sci U S A. 2020;117:2579-2587 pubmed publisher |
| Chen P, Chen Y, Chu T, Ma T, Wu M, Lin H, et al. Nucleolar control by a non-apoptotic p53-caspases-deubiquitinylase axis promotes resistance to bacterial infection. FASEB J. 2020;34:1107-1121 pubmed publisher |
| Wong I, Neo J, Oehler J, Schafhauser S, Osman F, Carr S, et al. The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast. elife. 2019;8: pubmed publisher |
| Ji C, Li Y, Kittredge A, Hopiavuori A, Ward N, Yao P, et al. Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations. Sci Rep. 2019;9:19026 pubmed publisher |
| Smith J, Ashander L, Ma Y, Rochet E, Furtado J. Model Systems for Studying Mechanisms of Ocular Toxoplasmosis. Methods Mol Biol. 2020;2071:297-321 pubmed publisher |
| Lopez E, Lee Rivera I, Alvarez Arce A, López Colomé A. Thrombin induces Ca2+-dependent glutamate release from RPE cells mediated by PLC/PKC and reverse Na+/Ca2+ exchange. Mol Vis. 2019;25:546-558 pubmed |
| Weed L, Ammar M, Zhou S, Wei Z, Serrano L, Sun J, et al. Safety of Same-Eye Subretinal Sequential Readministration of AAV2-hRPE65v2 in Non-human Primates. Mol Ther Methods Clin Dev. 2019;15:133-148 pubmed publisher |
| Gardiner K, Cideciyan A, Swider M, Dufour V, Sumaroka A, Komaromy A, et al. Long-Term Structural Outcomes of Late-Stage RPE65 Gene Therapy. Mol Ther. 2020;28:266-278 pubmed publisher |
| Lian C, Lou H, Zhang J, Tian H, Ou Q, Xu J, et al. MicroRNA-24 protects retina from degeneration in rats by down-regulating chitinase-3-like protein 1. Exp Eye Res. 2019;188:107791 pubmed publisher |
| Hellinen L, Pirskanen L, Tengvall Unadike U, Urtti A, Reinisalo M. Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties. Pharmaceutics. 2019;11: pubmed publisher |
| Wright T, Brisson B, Wood G, Oblak M, Mutsaers A, Sabine V, et al. Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs. Cytometry A. 2019;95:997-1007 pubmed publisher |
| Scruggs B, Jiao C, Cranston C, Kaalberg E, Wang K, Russell S, et al. Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments. Stem Cells Transl Med. 2019;8:797-809 pubmed publisher |
| Cai H, Gong J, Abriola L, Hoyer D, Nyscf Global Stem Cell Array Team -, Noggle S, et al. High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD. Exp Eye Res. 2019;185:107641 pubmed publisher |
| Cho I, Park S, Lee S, Nah S, Park H, Yang J, et al. The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation. Lasers Med Sci. 2019;34:571-581 pubmed publisher |
| Bhutto I, Ogura S, Baldeosingh R, McLeod D, Lutty G, Edwards M. An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy. Invest Ophthalmol Vis Sci. 2018;59:AMD143-AMD151 pubmed publisher |
| Tiku V, Kew C, Mehrotra P, Ganesan R, Robinson N, Antebi A. Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance. Nat Commun. 2018;9:3607 pubmed publisher |
| Kaur G, Tan L, Rathnasamy G, La Cunza N, Germer C, Toops K, et al. Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration. Proc Natl Acad Sci U S A. 2018;115:9014-9019 pubmed publisher |
| Chae J, Rho C, Shin J, Lyu J, Kang S. Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. Korean J Ophthalmol. 2018;32:328-338 pubmed publisher |
| Gao Z, Liao Y, Chen C, Liao C, He D, Chen J, et al. Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina. J Biol Chem. 2018;293:14507-14519 pubmed publisher |
| Llonch S, Carido M, Ader M. Organoid technology for retinal repair. Dev Biol. 2018;433:132-143 pubmed publisher |
| Li Y, Zhang Y, Xu Y, Kittredge A, Ward N, Chen S, et al. Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca2+-dependent Cl- currents in human RPE. elife. 2017;6: pubmed publisher |
| Liao R, Yan F, Zeng Z, Wang H, Qiu K, Xu J, et al. IGF-1 activates PI3K/Akt signaling to protect human retinal pigment epithelial cells from amiodarone-induced oxidative injury. Br J Pharmacol. 2017;: pubmed publisher |
| Sun J, Huang P, Liang J, Li J, Shen M, She X, et al. Cooperation of Rel family members in regulating A?1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells. Cell Death Dis. 2017;8:e3115 pubmed publisher |
| Buchwalter A, Hetzer M. Nucleolar expansion and elevated protein translation in premature aging. Nat Commun. 2017;8:328 pubmed publisher |
| Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, et al. Small nucleoli are a cellular hallmark of longevity. Nat Commun. 2017;8:16083 pubmed publisher |
| Steinfeld J, Steinfeld I, Bausch A, Coronato N, Hampel M, Depner H, et al. BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling. Biol Open. 2017;6:979-992 pubmed publisher |
| Chowers G, Cohen M, Marks Ohana D, Stika S, Eijzenberg A, Banin E, et al. Course of Sodium Iodate-Induced Retinal Degeneration in Albino and Pigmented Mice. Invest Ophthalmol Vis Sci. 2017;58:2239-2249 pubmed publisher |
| Zheng W, Meng Q, Wang H, Yan F, Little P, Deng X, et al. IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway. Mol Neurobiol. 2018;55:1915-1927 pubmed publisher |
| Zhou T, Rivera J, Bhosle V, Lahaie I, Shao Z, Tahiri H, et al. Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1?. Am J Pathol. 2016;186:3100-3116 pubmed publisher |
| Robaszkiewicz E, Idziak Helmcke D, Tkacz M, Chrominski K, Hasterok R. The arrangement of Brachypodium distachyon chromosomes in interphase nuclei. J Exp Bot. 2016;67:5571-5583 pubmed |
| Lyzogubov V, Bora P, Wu X, Horn L, de Roque R, Rudolf X, et al. The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration-Like Phenotype. Am J Pathol. 2016;186:2088-2104 pubmed publisher |
| Iwabe S, Ying G, Aguirre G, Beltran W. Assessment of visual function and retinal structure following acute light exposure in the light sensitive T4R rhodopsin mutant dog. Exp Eye Res. 2016;146:341-53 pubmed publisher |
| Di Lauro S, Rodriguez Crespo D, Gayoso M, Garcia Gutierrez M, Pastor J, Srivastava G, et al. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Mol Vis. 2016;22:243-53 pubmed |
| Ayala Peña V, Pilotti F, Volonté Y, Rotstein N, Politi L, German O. Protective effects of retinoid x receptors on retina pigment epithelium cells. Biochim Biophys Acta. 2016;1863:1134-45 pubmed publisher |
| Chen M, Rajapakse D, Fraczek M, Luo C, Forrester J, Xu H. Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis. Aging Cell. 2016;15:436-45 pubmed publisher |
| Parker J, Mitrousis N, Shoichet M. Hydrogel for Simultaneous Tunable Growth Factor Delivery and Enhanced Viability of Encapsulated Cells in Vitro. Biomacromolecules. 2016;17:476-84 pubmed publisher |
| Cashman S, Gracias J, Adhi M, Kumar Singh R. Adenovirus-mediated delivery of Factor H attenuates complement C3 induced pathology in the murine retina: a potential gene therapy for age-related macular degeneration. J Gene Med. 2015;17:229-43 pubmed publisher |
| Itatani Y, Sonoshita M, Kakizaki F, Okawa K, Stifani S, Itoh H, et al. Characterization of Aes nuclear foci in colorectal cancer cells. J Biochem. 2016;159:133-40 pubmed publisher |
| Yan R, He L, Zhan W, Wang S. Induction of ectopic retina-like tissue by transgenic expression of neurogenin. PLoS ONE. 2015;10:e0116171 pubmed publisher |
| Prasad T, Verma A, Li Q. Expression and cellular localization of the Mas receptor in the adult and developing mouse retina. Mol Vis. 2014;20:1443-55 pubmed |
| Lee C, Tsai Y, Kao C, Lee L, Lai H, Ma T, et al. Mutation of a Nopp140 gene dao-5 alters rDNA transcription and increases germ cell apoptosis in C. elegans. Cell Death Dis. 2014;5:e1158 pubmed publisher |
| Steinfeld J, Steinfeld I, Coronato N, Hampel M, Layer P, Araki M, et al. RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling. Development. 2013;140:4959-69 pubmed publisher |
| Guziewicz K, Zangerl B, Komaromy A, Iwabe S, Chiodo V, Boye S, et al. Recombinant AAV-mediated BEST1 transfer to the retinal pigment epithelium: analysis of serotype-dependent retinal effects. PLoS ONE. 2013;8:e75666 pubmed publisher |
| Inoue Y, Hasegawa S, Yamada T, Date Y, Mizutani H, Nakata S, et al. Lignin Induces ES Cells to Differentiate into Neuroectodermal Cells through Mediation of the Wnt Signaling Pathway. PLoS ONE. 2013;8:e66376 pubmed publisher |
| Singh A, Srivastava G, Martin L, Alonso M, Pastor J. Bioactive substrates for human retinal pigment epithelial cell growth from elastin-like recombinamers. J Biomed Mater Res A. 2014;102:639-46 pubmed publisher |
| Shirasawa M, Sonoda S, Terasaki H, Arimura N, Otsuka H, Yamashita T, et al. TNF-? disrupts morphologic and functional barrier properties of polarized retinal pigment epithelium. Exp Eye Res. 2013;110:59-69 pubmed publisher |
| Wallace C, Moir G, Malone D, Duncan L, Devarajan G, Crane I. Regulation of T-lymphocyte CCL3 and CCL4 production by retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2013;54:722-30 pubmed publisher |
| Fernandez Bueno I, Rodriguez de la Rua E, Hileeto D, Parrado M, Regueiro Purriños M, Sala Puigdollers A, et al. Histology and immunochemistry evaluation of autologous translocation of retinal pigment epithelium-choroid graft in porcine eyes. Acta Ophthalmol. 2013;91:e125-32 pubmed publisher |
| He Y, Ge J, Burke J, Myers R, Dong Z, Tombran Tink J. Mitochondria impairment correlates with increased sensitivity of aging RPE cells to oxidative stress. J Ocul Biol Dis Infor. 2010;3:92-108 pubmed publisher |
| Jiang G, Sun D, Kaplan H, Shao H. Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells. PLoS ONE. 2012;7:e40510 pubmed publisher |
| Cho M, Kim S, Ku S, Park J, Lee H, Yoo D, et al. Generation of retinal pigment epithelial cells from human embryonic stem cell-derived spherical neural masses. Stem Cell Res. 2012;9:101-9 pubmed publisher |
| Krohne T, Westenskow P, Kurihara T, Friedlander D, Lehmann M, Dorsey A, et al. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Transl Med. 2012;1:96-109 pubmed |
| Xia H, Krebs M, Kaushal S, Scott E. Enhanced retinal pigment epithelium regeneration after injury in MRL/MpJ mice. Exp Eye Res. 2011;93:862-72 pubmed publisher |
| Kleinman M, Kaneko H, Cho W, Dridi S, Fowler B, Blandford A, et al. Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Mol Ther. 2012;20:101-8 pubmed publisher |
| Leung K, Gvritishvili A, Liu Y, Tombran Tink J. ZIP2 and ZIP4 mediate age-related zinc fluxes across the retinal pigment epithelium. J Mol Neurosci. 2012;46:122-37 pubmed publisher |
| Harness J, Turovets N, Seiler M, Nistor G, Altun G, Agapova L, et al. Equivalence of conventionally-derived and parthenote-derived human embryonic stem cells. PLoS ONE. 2011;6:e14499 pubmed publisher |
| Hern ndez M, Pearce Kelling S, Rodriguez F, Aguirre G, Vecino E. Altered expression of retinal molecular markers in the canine RPE65 model of Leber congenital amaurosis. Invest Ophthalmol Vis Sci. 2010;51:6793-802 pubmed publisher |
| Ke Y, Jiang G, Sun D, Kaplan H, Shao H. Retinal Astrocytes respond to IL-17 differently than Retinal Pigment Epithelial cells. J Leukoc Biol. 2009;86:1377-84 pubmed publisher |
| Sonoda S, Spee C, Barron E, Ryan S, Kannan R, Hinton D. A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nat Protoc. 2009;4:662-73 pubmed publisher |
| Gu D, Beltran W, Pearce Kelling S, Li Z, Acland G, Aguirre G. Steroids do not prevent photoreceptor degeneration in the light-exposed T4R rhodopsin mutant dog retina irrespective of AP-1 inhibition. Invest Ophthalmol Vis Sci. 2009;50:3482-94 pubmed publisher |
| Harris J, Fisher R, Jorgensen M, Kaushal S, Scott E. CD133 progenitor cells from the bone marrow contribute to retinal pigment epithelium repair. Stem Cells. 2009;27:457-66 pubmed publisher |
| Thumann G, Viethen A, Gaebler A, Walter P, Kaempf S, Johnen S, et al. The in vitro and in vivo behaviour of retinal pigment epithelial cells cultured on ultrathin collagen membranes. Biomaterials. 2009;30:287-94 pubmed publisher |
| Vossmerbaeumer U, Kuehl S, Kern S, Kluter H, Jonas J, Bieback K. Induction of retinal pigment epithelium properties in ciliary margin progenitor cells. Clin Exp Ophthalmol. 2008;36:358-66 pubmed publisher |
| Kaempf S, Walter P, Salz A, Thumann G. Novel organotypic culture model of adult mammalian neurosensory retina in co-culture with retinal pigment epithelium. J Neurosci Methods. 2008;173:47-58 pubmed publisher |
| Chen M, Muckersie E, Robertson M, Fraczek M, Forrester J, Xu H. Characterization of a spontaneous mouse retinal pigment epithelial cell line B6-RPE07. Invest Ophthalmol Vis Sci. 2008;49:3699-706 pubmed publisher |
| Lall M, Ferrell J, Nagar S, Fleisher L, McGahan M. Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase. Invest Ophthalmol Vis Sci. 2008;49:310-9 pubmed publisher |
| Jiang G, Ke Y, Sun D, Han G, Kaplan H, Shao H. Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice. Invest Ophthalmol Vis Sci. 2008;49:282-9 pubmed publisher |
| Jacobson S, Aleman T, Cideciyan A, Heon E, Golczak M, Beltran W, et al. Human cone photoreceptor dependence on RPE65 isomerase. Proc Natl Acad Sci U S A. 2007;104:15123-8 pubmed |
| Jacobson A, Yan C, Gao Q, Rincon Skinner T, Rivera A, Edwards J, et al. Aging enhances pressure-induced arterial superoxide formation. Am J Physiol Heart Circ Physiol. 2007;293:H1344-50 pubmed |
