| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; fig 4b
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- immunohistochemistry - paraffin section; human
| Murtas D, Piras F, Minerba L, Maxia C, Ferreli C, Demurtas P, et al. Activated Notch1 expression is associated with angiogenesis in cutaneous melanoma. Clin Exp Med. 2015;15:351-60 pubmed publisher |
| Heroux M, Chesnik M, Halligan B, Al Gizawiy M, Connelly J, Mueller W, et al. Comprehensive characterization of glioblastoma tumor tissues for biomarker identification using mass spectrometry-based label-free quantitative proteomics. Physiol Genomics. 2014;46:467-81 pubmed publisher |
- immunocytochemistry; human
- immunohistochemistry; human
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- immunohistochemistry; human
| Loudig O, Brandwein Gensler M, Kim R, Lin J, Isayeva T, Liu C, et al. Illumina whole-genome complementary DNA-mediated annealing, selection, extension and ligation platform: assessing its performance in formalin-fixed, paraffin-embedded samples and identifying invasion pattern-related genes in oral squamous cell carcin. Hum Pathol. 2011;42:1911-22 pubmed publisher |
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- immunocytochemistry; human
| Ropolo M, Daga A, Griffero F, Foresta M, Casartelli G, Zunino A, et al. Comparative analysis of DNA repair in stem and nonstem glioma cell cultures. Mol Cancer Res. 2009;7:383-92 pubmed publisher |
- immunocytochemistry; human
| Castriconi R, Daga A, Dondero A, Zona G, Poliani P, Melotti A, et al. NK cells recognize and kill human glioblastoma cells with stem cell-like properties. J Immunol. 2009;182:3530-9 pubmed publisher |
- immunocytochemistry; human
| Gangemi R, Griffero F, Marubbi D, Perera M, Capra M, Malatesta P, et al. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells. 2009;27:40-8 pubmed publisher |
- immunocytochemistry; human
| Wright L, Li J, Caldwell M, Wallace K, Johnson J, Svendsen C. Gene expression in human neural stem cells: effects of leukemia inhibitory factor. J Neurochem. 2003;86:179-95 pubmed |
- immunocytochemistry; human
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| Kuo H, Wu R, Li S, Yang A, Kong A. Anthocyanin Delphinidin Prevents Neoplastic Transformation of Mouse Skin JB6 P+ Cells: Epigenetic Re-activation of Nrf2-ARE Pathway. AAPS J. 2019;21:83 pubmed publisher |
| Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, et al. Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis. Int J Mol Sci. 2019;20: pubmed publisher |
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| Adamska A, Araszkiewicz A, Pilacinski S, Gandecka A, Grzelka A, Kowalska K, et al. Dermal microvessel density and maturity is closely associated with atherogenic dyslipidemia and accumulation of advanced glycation end products in adult patients with type 1 diabetes. Microvasc Res. 2019;121:46-51 pubmed publisher |
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| Meliso F, Micali D, Silva C, Sabedot T, Coetzee S, Koch A, et al. SIRT1 regulates Mxd1 during malignant melanoma progression. Oncotarget. 2017;8:114540-114553 pubmed publisher |
| Yang J, Wu R, Li W, Gao L, Yang Y, Li P, et al. The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells. Mol Carcinog. 2018;57:512-521 pubmed publisher |
| Li W, Su Z, Guo Y, Zhang C, Wu R, Gao L, et al. Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells. Chem Res Toxicol. 2017;: pubmed publisher |
| Chu Y, Ko C, Wang S, Lin P, Wang H, Lin W, et al. Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia. Cell Death Dis. 2017;8:e3167 pubmed publisher |
| Heffernan J, McNamara J, Borwege S, Vernon B, Sanai N, Mehta S, et al. PNIPAAm-co-Jeffamine® (PNJ) scaffolds as in vitro models for niche enrichment of glioblastoma stem-like cells. Biomaterials. 2017;143:149-158 pubmed publisher |
| Kuang H, Tang Z, Zhang C, Wang Z, Li W, Yang C, et al. Taxifolin Activates the Nrf2 Anti-Oxidative Stress Pathway in Mouse Skin Epidermal JB6 P+ Cells through Epigenetic Modifications. Int J Mol Sci. 2017;18: pubmed publisher |
| Sheikh M, Malik Y, Zhu X. RA-Induced Transcriptional Silencing of Checkpoint Kinase-2 through Promoter Methylation by Dnmt3b Is Required for Neuronal Differentiation of P19 Cells. J Mol Biol. 2017;429:2463-2473 pubmed publisher |
| Miozzo F, Arnould H, de Thonel A, Schang A, Sabéran Djoneidi D, Baudry A, et al. Alcohol exposure promotes DNA methyltransferase DNMT3A upregulation through reactive oxygen species-dependent mechanisms. Cell Stress Chaperones. 2018;23:115-126 pubmed publisher |
| He J, Pei L, Jiang H, Yang W, Chen J, Liang H. Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation. J Cancer. 2017;8:1187-1196 pubmed publisher |
| Iwata R, Maruyama M, Ito T, Nakano Y, Kanemura Y, Koike T, et al. Establishment of a tumor sphere cell line from a metastatic brain neuroendocrine tumor. Med Mol Morphol. 2017;50:211-219 pubmed publisher |
| Szarc vel Szic K, Declerck K, Crans R, Diddens J, Scherf D, Gerhäuser C, et al. Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A. Oncotarget. 2017;8:40434-40453 pubmed publisher |
| Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma. World J Gastroenterol. 2017;23:1568-1575 pubmed publisher |
| Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed publisher |
| Neri F, Rapelli S, Krepelova A, Incarnato D, Parlato C, Basile G, et al. Intragenic DNA methylation prevents spurious transcription initiation. Nature. 2017;543:72-77 pubmed publisher |
| Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed publisher |
| Koh H, Scruggs A, Huang S. Transforming Growth Factor-β1 Increases DNA Methyltransferase 1 and 3a Expression through Distinct Post-transcriptional Mechanisms in Lung Fibroblasts. J Biol Chem. 2016;291:19287-98 pubmed publisher |
| Daniel F, Alves S, Vieira D, Biz M, Daniel I, Modolo F. Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas. J Oral Pathol Med. 2016;45:774-779 pubmed publisher |
| Li W, Pung D, Su Z, Guo Y, Zhang C, Yang A, et al. Epigenetics Reactivation of Nrf2 in Prostate TRAMP C1 Cells by Curcumin Analogue FN1. Chem Res Toxicol. 2016;29:694-703 pubmed publisher |
| Hong B, Su Z, Zhang C, Yang Y, Guo Y, Li W, et al. Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway. AAPS J. 2016;18:659-69 pubmed publisher |
| Miao C, Qin D, Du C, Ye H, Shi W, Xiong Y, et al. DNMT1 activates the canonical Wnt signaling in rheumatoid arthritis model rats via a crucial functional crosstalk between miR-152 and the DNMT1, MeCP2. Int Immunopharmacol. 2015;28:344-53 pubmed publisher |
| Kopparapu P, Miranda C, Fogelstrand L, Mishra K, Andersson P, Kanduri C, et al. MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia. FEBS J. 2015;282:1939-52 pubmed publisher |
| Neri F, Incarnato D, Krepelova A, Rapelli S, Anselmi F, Parlato C, et al. Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics. Cell Rep. 2015;10:674-683 pubmed publisher |
| Guo Y, Shu L, Zhang C, Su Z, Kong A. Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1. Biochem Pharmacol. 2015;94:69-78 pubmed publisher |
| Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed publisher |
| Bittencourt D, Lee B, Gao L, Gerke D, Stallcup M. Role of distinct surfaces of the G9a ankyrin repeat domain in histone and DNA methylation during embryonic stem cell self-renewal and differentiation. Epigenetics Chromatin. 2014;7:27 pubmed publisher |
| Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, et al. In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nat Biotechnol. 2015;33:102-6 pubmed publisher |
| Wang L, Zhang C, Guo Y, Su Z, Yang Y, Shu L, et al. Blocking of JB6 cell transformation by tanshinone IIA: epigenetic reactivation of Nrf2 antioxidative stress pathway. AAPS J. 2014;16:1214-25 pubmed publisher |
| Fang M, Ou J, Hutchinson L, Green M. The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. Mol Cell. 2014;55:904-915 pubmed publisher |
| Guimarães D, Antunes D, Duarte C, Ferro L, Nunes F. DNA methyltransferase immunohistochemical expression in odontogenic tumours. J Oral Pathol Med. 2015;44:59-66 pubmed publisher |
| Fang P, Zhang D, Cheng Z, Yan C, Jiang X, Kruger W, et al. Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis. Diabetes. 2014;63:4275-90 pubmed publisher |
| Tajrishi M, Shin J, Hetman M, Kumar A. DNA methyltransferase 3a and mitogen-activated protein kinase signaling regulate the expression of fibroblast growth factor-inducible 14 (Fn14) during denervation-induced skeletal muscle atrophy. J Biol Chem. 2014;289:19985-99 pubmed publisher |
| Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. Deregulation of RB1 expression by loss of imprinting in human hepatocellular carcinoma. J Pathol. 2014;233:392-401 pubmed publisher |
| Paredes Gonzalez X, Fuentes F, Su Z, Kong A. Apigenin reactivates Nrf2 anti-oxidative stress signaling in mouse skin epidermal JB6 P + cells through epigenetics modifications. AAPS J. 2014;16:727-35 pubmed publisher |
| Chuang C, Wang W, Li C, Ko C, Chou Y, Chuu C, et al. The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer. Cell Death Dis. 2014;5:e1220 pubmed publisher |
| Calabrese R, Valentini E, Ciccarone F, Guastafierro T, Bacalini M, Ricigliano V, et al. TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells. Biochim Biophys Acta. 2014;1842:1130-6 pubmed publisher |
| Serra R, Fang M, Park S, Hutchinson L, Green M. A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. elife. 2014;3:e02313 pubmed publisher |
| Neidhart M, Karouzakis E, Jungel A, Gay R, Gay S. Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis. Arthritis Rheumatol. 2014;66:1723-33 pubmed publisher |
| Teneng I, Tellez C, Picchi M, Klinge D, Yingling C, Snider A, et al. Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer. Oncogene. 2015;34:621-30 pubmed publisher |
| Su Z, Zhang C, Lee J, Shu L, Wu T, Khor T, et al. Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane. Cancer Prev Res (Phila). 2014;7:319-29 pubmed publisher |
| Hara E, Ono M, Eguchi T, Kubota S, Pham H, Sonoyama W, et al. miRNA-720 controls stem cell phenotype, proliferation and differentiation of human dental pulp cells. PLoS ONE. 2013;8:e83545 pubmed publisher |
| Otani J, Kimura H, Sharif J, Endo T, Mishima Y, Kawakami T, et al. Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells. PLoS ONE. 2013;8:e82961 pubmed publisher |
| Watson C, Collier P, Tea I, Neary R, Watson J, Robinson C, et al. Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype. Hum Mol Genet. 2014;23:2176-88 pubmed publisher |
| Kanduri M, Sander B, Ntoufa S, Papakonstantinou N, Sutton L, Stamatopoulos K, et al. A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma. Epigenetics. 2013;8:1280-8 pubmed publisher |
| Giraldo A, DeCourcy K, Ball S, Hylan D, Ayares D. Gene expression of Dnmt1 isoforms in porcine oocytes, embryos, and somatic cells. Cell Reprogram. 2013;15:309-21 pubmed publisher |
| Sheikh M, Malik Y, Yu H, Lai M, Wang X, Zhu X. Epigenetic regulation of Dpp6 expression by Dnmt3b and its novel role in the inhibition of RA induced neuronal differentiation of P19 cells. PLoS ONE. 2013;8:e55826 pubmed publisher |
| Anwar S, Albat C, Krech T, Hasemeier B, Schipper E, Schweitzer N, et al. Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer. 2013;133:660-70 pubmed publisher |
| Grau L, Luque Garcia J, Gonzalez Peramato P, Theodorescu D, Palou J, Fernández Gómez J, et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS ONE. 2013;8:e53328 pubmed publisher |
| Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma. PLoS ONE. 2012;7:e49462 pubmed publisher |
| Ji W, Yang L, Yuan J, Yang L, Zhang M, Qi D, et al. MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism. Carcinogenesis. 2013;34:446-53 pubmed publisher |
| Ip J, Canham P, Choo K, Inaba Y, Jacobs S, Kalitsis P, et al. Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells. PLoS Genet. 2012;8:e1002919 pubmed publisher |
| Zimmermann N, Zschocke J, Perisic T, Yu S, Holsboer F, Rein T. Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. Biochem J. 2012;448:93-102 pubmed publisher |
| Mohammad F, Pandey G, Mondal T, Enroth S, Redrup L, Gyllensten U, et al. Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing. Development. 2012;139:2792-803 pubmed publisher |
| Bhardwaj A, Song H, Beildeck M, Kerkhofs S, Castoro R, Shanker S, et al. DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis. Mol Endocrinol. 2012;26:538-49 pubmed publisher |
| Selvakumar T, Gjidoda A, Hovde S, Henry R. Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases. J Biol Chem. 2012;287:7039-50 pubmed publisher |
| Kadriu B, Guidotti A, Chen Y, Grayson D. DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. J Comp Neurol. 2012;520:1951-64 pubmed publisher |
| Yang J, Corsello T, Ma Y. Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases. J Biol Chem. 2012;287:1996-2005 pubmed publisher |
| Rochlin I, Turbow D, GOMEZ F, Ninivaggi D, Campbell S. Predictive mapping of human risk for West Nile virus (WNV) based on environmental and socioeconomic factors. PLoS ONE. 2011;6:e23280 pubmed publisher |
| Saito S, Kato J, Hiraoka S, Horii J, Suzuki H, Higashi R, et al. DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status. Inflamm Bowel Dis. 2011;17:1955-65 pubmed publisher |
| Fan H, Cinar M, Phatsara C, Tesfaye D, Tholen E, Looft C, et al. Molecular mechanism underlying the differential MYF6 expression in postnatal skeletal muscle of Duroc and Pietrain breeds. Gene. 2011;486:8-14 pubmed publisher |
| Dhawan S, Georgia S, Tschen S, Fan G, Bhushan A. Pancreatic ? cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell. 2011;20:419-29 pubmed publisher |
| Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed publisher |
| Molognoni F, Cruz A, Meliso F, Morais A, Souza C, Xander P, et al. Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics. 2011;6:450-64 pubmed |
| Yamanaka K, Sakatani M, Kubota K, Balboula A, Sawai K, Takahashi M. Effects of downregulating DNA methyltransferase 1 transcript by RNA interference on DNA methylation status of the satellite I region and in vitro development of bovine somatic cell nuclear transfer embryos. J Reprod Dev. 2011;57:393-402 pubmed |
| Dalvai M, Mondesert O, Bourdon J, Ducommun B, Dozier C. Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors. Oncogene. 2011;30:2282-8 pubmed publisher |
| Teneng I, Montoya Durango D, Quertermous J, Lacy M, Ramos K. Reactivation of L1 retrotransposon by benzo(a)pyrene involves complex genetic and epigenetic regulation. Epigenetics. 2011;6:355-67 pubmed |
| Daniel F, Rivero E, Modolo F, Lopes T, Salum F. Immunohistochemical expression of DNA methyltransferases 1, 3a and 3b in oral leukoplakias and squamous cell carcinomas. Arch Oral Biol. 2010;55:1024-30 pubmed publisher |
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| Wu Y, Alvarez M, Slamon D, Koeffler P, Vadgama J. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer. 2010;10:32 pubmed publisher |
| Perisic T, Zimmermann N, Kirmeier T, Asmus M, Tuorto F, Uhr M, et al. Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology. 2010;35:792-805 pubmed publisher |
| Ye Y, McDevitt M, Guo M, Zhang W, Galm O, Gore S, et al. Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies. Cancer Res. 2009;69:8482-90 pubmed publisher |
| Hwang C, Song K, Kim C, Choi H, Guo X, Law P, et al. Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. J Cell Mol Med. 2009;13:3591-615 pubmed publisher |
| Zampieri M, Passananti C, Calabrese R, Perilli M, Corbi N, De Cave F, et al. Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. PLoS ONE. 2009;4:e4717 pubmed publisher |
| Yamagata Y, Asada H, Tamura I, Lee L, Maekawa R, Taniguchi K, et al. DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen. Hum Reprod. 2009;24:1126-32 pubmed publisher |
| Lin H, Zuo T, Lin C, Kuo C, Liyanarachchi S, Sun S, et al. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res. 2008;68:10257-66 pubmed publisher |
| Ko C, Hsu H, Shen M, Chang W, Wang J. Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem. 2008;283:30919-32 pubmed publisher |
| O Hagan H, Mohammad H, Baylin S. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet. 2008;4:e1000155 pubmed publisher |
| Guastafierro T, Cecchinelli B, Zampieri M, Reale A, Riggio G, Sthandier O, et al. CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery. J Biol Chem. 2008;283:21873-80 pubmed publisher |
| Xia G, Schneider Stock R, Diestel A, Habold C, Krueger S, Roessner A, et al. Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation. Biochem Biophys Res Commun. 2008;369:526-31 pubmed publisher |
| Russell D, Betts D. Alternative splicing and expression analysis of bovine DNA methyltransferase 1. Dev Dyn. 2008;237:1051-9 pubmed publisher |
| Hodge D, Cho E, Copeland T, Guszczynski T, Yang E, Seth A, et al. IL-6 enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase. Cancer Genomics Proteomics. 2007;4:387-98 pubmed |
| Ji W, Yang L, Yu L, Yuan J, Hu D, Zhang W, et al. Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells. Carcinogenesis. 2008;29:1267-75 pubmed publisher |
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