product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SCP3/SYCP3 Antibody - BSA Free
catalog :
NB300-231
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
8H10D10
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 4a
Mu X, Tu Z, Chen X, Hong Y, Geng Y, Zhang Y, et al. In utero Exposure to Excessive Estrogen Impairs Homologous Recombination and Oogenesis via Estrogen Receptor 2 in Mice. Front Cell Dev Biol. 2021;9:669732 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 8
  • western blot; mouse; 1:200; loading ...; fig 4
  • western blot; human; 1:500; loading ...; fig 2
Parvanov E, Tian H, Billings T, Saxl R, Spruce C, Aithal R, et al. PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017;28:488-499 pubmed publisher
Dumont B, Gatti D, Ballinger M, Lin D, Phifer Rixey M, Sheehan M, et al. Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models. PLoS Genet. 2024;20:e1011228 pubmed publisher
Li L, Krasnykov K, Homolka D, Gos P, Mendel M, Fish R, et al. The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition. Mol Cell. 2022;82:1678-1690.e12 pubmed publisher
Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, et al. RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes. Sci Adv. 2022;8:eabk1789 pubmed publisher
Lei W, Li Y, Meng T, Ning Y, Sun S, Zhang C, et al. Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis. Cell Death Dis. 2021;12:883 pubmed publisher
Tian H, Petkov P. Mouse EWSR1 is crucial for spermatid post-meiotic transcription and spermiogenesis. Development. 2021;148: pubmed publisher
Tian H, Billings T, Petkov P. EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis protein REC8. Mol Biol Cell. 2021;32:1-14 pubmed publisher
Mc Fie M, Koneva L, Collins I, Coveney C, Clube A, Chanalaris A, et al. Ciliary proteins specify the cell inflammatory response by tuning NFκB signalling, independently of primary cilia. J Cell Sci. 2020;133: pubmed publisher
Fisher I, Jenkins M, Tall G, Burke J, Smrcka A. Activation of Phospholipase C β by Gβγ and Gαq Involves C-Terminal Rearrangement to Release Autoinhibition. Structure. 2020;28:810-819.e5 pubmed publisher
Zhang M, Liu L, Cao X, Liu Y, Di J, Huang X, et al. Efficiently accumulating germ-like stem cells from mouse postnatal ovary by in situ tissue culture. Dev Growth Differ. 2020;62:223-231 pubmed publisher
Zhang R, Ma J, Avery J, Sambandam V, Nguyen T, Xu B, et al. GLI1 Inhibitor SRI-38832 Attenuates Chemotherapeutic Resistance by Downregulating NBS1 Transcription in BRAFV600E Colorectal Cancer. Front Oncol. 2020;10:241 pubmed publisher
Nawasreh M, Alzyoud E, Al Mazaydeh Z, Rammaha M, Yasin S, Tahtamouni L. Biological activity and apoptotic signaling pathway of C11-functionalized cephalostatin 1 analogues. Steroids. 2020;158:108602 pubmed publisher
Germoush M, Elgebaly H, Hassan S, Kamel E, Bin Jumah M, Mahmoud A. Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes. Antioxidants (Basel). 2019;9: pubmed publisher
Lei W, Han F, Hu M, Liang Q, Meng T, Zhou Q, et al. Protein phosphatase 6 is a key factor regulating spermatogenesis. Cell Death Differ. 2019;: pubmed publisher
Li J, Jeong S, Xiong B, Tseng A, Mahon A, Isaacman S, et al. Repurposing pyridoxamine for therapeutic intervention of intravascular cell-cell interactions in mouse models of sickle cell disease. Haematologica. 2019;: pubmed publisher
Daniels A, Singh M. Sterically stabilized siRNA:gold nanocomplexes enhance c-MYC silencing in a breast cancer cell model. Nanomedicine (Lond). 2019;14:1387-1401 pubmed publisher
Tu Z, Mu X, Chen X, Geng Y, Zhang Y, Li Q, et al. Dibutyl phthalate exposure disrupts the progression of meiotic prophase I by interfering with homologous recombination in fetal mouse oocytes. Environ Pollut. 2019;252:388-398 pubmed publisher
Phelps C, Lindsey Boltz L, Sancar A, Mu D. Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin. Sci Rep. 2019;9:7990 pubmed publisher
Bhattacharyya T, Walker M, Powers N, Brunton C, Fine A, Petkov P, et al. Prdm9 and Meiotic Cohesin Proteins Cooperatively Promote DNA Double-Strand Break Formation in Mammalian Spermatocytes. Curr Biol. 2019;29:1002-1018.e7 pubmed publisher
Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, et al. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis. Cell Res. 2019;29:221-232 pubmed publisher
Tian H, Billings T, Petkov P. CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018;14:e1007657 pubmed publisher
Adams S, Maezawa S, Alavattam K, Abe H, Sakashita A, Shroder M, et al. RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes. PLoS Genet. 2018;14:e1007233 pubmed publisher
Testa E, Nardozi D, Antinozzi C, Faieta M, Di Cecca S, Caggiano C, et al. H2AFX and MDC1 promote maintenance of genomic integrity in male germ cells. J Cell Sci. 2018;131: pubmed publisher
Tahtamouni L, Nawasreh M, Al Mazaydeh Z, Al Khateeb R, Abdellatif R, Bawadi R, et al. Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathway. Eur J Pharmacol. 2018;818:400-409 pubmed publisher
Wojtas M, Pandey R, Mendel M, Homolka D, Sachidanandam R, Pillai R. Regulation of m6A Transcripts by the 3'?5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline. Mol Cell. 2017;68:374-387.e12 pubmed publisher
Howlett E, Jensen N, Belmonte F, Zafar F, Hu X, Kluss J, et al. LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease. Hum Mol Genet. 2017;26:4340-4351 pubmed publisher
Dai J, Voloshin O, Potapova S, Camerini Otero R. Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis. Cell Rep. 2017;18:1383-1394 pubmed publisher
Kim K, Tseng A, Barazia A, Italiano J, Cho J. DREAM plays an important role in platelet activation and thrombogenesis. Blood. 2017;129:209-225 pubmed publisher
Ikegami K, Atsumi Y, Yorinaga E, Ono H, Murayama I, Nakane Y, et al. Low temperature-induced circulating triiodothyronine accelerates seasonal testicular regression. Endocrinology. 2015;156:647-59 pubmed publisher
product information
master code :
NB300-231
SKU :
NB300-231
product name :
SCP3/SYCP3 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SCP3/SYCP3 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SCP3/SYCP3. This antibody reacts with chicken,human,mouse. The SCP3/SYCP3 Antibody - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Iterative Bleaching Extends Multiplexity,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Western Blot.
target :
SCP3/SYCP3
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to the C-terminal region of the mouse SCP3 protein. [UniProt# P70281]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Chicken,Human,Mouse
gene symbol :
SYCP3
applications :
IF/IHC,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Iterative Bleaching Extends Multiplexity,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Western Blot
USD :
409 USD
alt names :
MGC71888, SCP3, SCP-3, SCP3 chromosome 3 open reading frame 8, SCP3 COR1, synaptonemal complex protein 3
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.