product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SCP1 Antibody - BSA Free
catalog :
NB300-229
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
biotin
clone name :
6C5cc
reactivity :
human, mouse, rat, chicken, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3b
Nagaoka S, Nakaki F, Miyauchi H, Nosaka Y, Ohta H, Yabuta Y, et al. ZGLP1 is a determinant for the oogenic fate in mice. Science. 2020;: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 8
  • western blot; mouse; 1:200; loading ...; fig 4
  • western blot; human; 1:500; loading ...; fig 2
Parvanov E, Tian H, Billings T, Saxl R, Spruce C, Aithal R, et al. PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017;28:488-499 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 5
Fu C, Begum K, Jordan P, He Y, Overbeek P. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS ONE. 2016;11:e0159800 pubmed publisher
Li Q, Yang G, Ren B, Liu X, Tang L, Shi Q, et al. ZC3H14 facilitates backsplicing by binding to exon-intron boundary and 3' UTR. Mol Cell. 2024;84:4314-4333.e9 pubmed publisher
Davies B, Zhang G, Moralli D, Alghadban S, Biggs D, Preece C, et al. Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice. Genome Res. 2023;33:2018-2027 pubmed publisher
Premkumar T, Paniker L, Kang R, Biot M, Humphrey E, Destain H, et al. Genetic dissection of crossover mutants defines discrete intermediates in mouse meiosis. Mol Cell. 2023;83:2941-2958.e7 pubmed publisher
Faber E, Sun L, Tang J, Roberts E, Ganeshkumar S, Wang N, et al. Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun. 2023;14:3213 pubmed publisher
Hirano K, Nonami Y, Nakamura Y, Sato T, Sato T, Ishiguro K, et al. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis. Commun Biol. 2022;5:504 pubmed publisher
Zhang J, Zhou X, Wan D, Yu L, Chen X, Yan T, et al. TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice. Front Cell Dev Biol. 2022;10:757042 pubmed publisher
Lee S, Kuramochi Miyagawa S, Nagamori I, Nakano T. Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs. RNA. 2022;28:683-696 pubmed publisher
Kagiwada S, Aramaki S, Wu G, Shin B, Kutejova E, Obridge D, et al. YAP establishes epiblast responsiveness to inductive signals for germ cell fate. Development. 2021;148: pubmed publisher
Takada Y, Yaman Deveci R, Shirakawa T, Sharif J, Tomizawa S, Miura F, et al. Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing. Development. 2021;148: pubmed publisher
Osawa Y, Murata K, Usui M, Kuba Y, Le H, Mikami N, et al. EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice. elife. 2021;10: pubmed publisher
Tian H, Billings T, Petkov P. EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis protein REC8. Mol Biol Cell. 2021;32:1-14 pubmed publisher
Larose H, Kent T, Ma Q, Shami A, Harerimana N, Li J, et al. Regulation of meiotic progression by Sertoli-cell androgen signaling. Mol Biol Cell. 2020;31:2841-2862 pubmed publisher
Spangenberg V, Arakelyan M, Cioffi M, Liehr T, Al Rikabi A, Martynova E, et al. Cytogenetic mechanisms of unisexuality in rock lizards. Sci Rep. 2020;10:8697 pubmed publisher
Hamada N, Hamazaki N, Shimamoto S, Hikabe O, Nagamatsu G, Takada Y, et al. Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in mice. PLoS Genet. 2020;16:e1008676 pubmed publisher
Zhang B, Tang Z, Li L, Lu L. NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis. Cell Death Differ. 2020;27:2176-2190 pubmed publisher
Zhang Y, Schroeder L, Lessard M, Kidd P, Chung J, Song Y, et al. Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging. Nat Methods. 2020;17:225-231 pubmed publisher
Hua R, Wei H, Liu C, Zhang Y, Liu S, Guo Y, et al. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Nucleic Acids Res. 2019;47:11755-11770 pubmed publisher
Lam K, Brick K, Cheng G, Pratto F, Camerini Otero R. Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis. Nat Commun. 2019;10:3821 pubmed publisher
Eyster C, Chuong H, Lee C, Pezza R, Dawson D. The pericentromeric heterochromatin of homologous chromosomes remains associated after centromere pairing dissolves in mouse spermatocyte meiosis. Chromosoma. 2019;: pubmed publisher
Tsang M, Gantchev J, Netchiporouk E, Moreau L, Ghazawi F, Glassman S, et al. A study of meiomitosis and novel pathways of genomic instability in cutaneous T-cell lymphomas (CTCL). Oncotarget. 2018;9:37647-37661 pubmed publisher
Huang G, Kaufman A, Ryan R, Romin Y, Huryn L, Bains S, et al. Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization. PLoS ONE. 2019;14:e0209995 pubmed publisher
Tian H, Billings T, Petkov P. CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018;14:e1007657 pubmed publisher
Abreu C, Prakash R, Romanienko P, Roig I, Keeney S, Jasin M. Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun. 2018;9:3961 pubmed publisher
Guiraldelli M, Felberg A, Almeida L, Parikh A, de Castro R, Pezza R. SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis. PLoS Genet. 2018;14:e1007381 pubmed publisher
Miyauchi H, Ohta H, Nagaoka S, Nakaki F, Sasaki K, Hayashi K, et al. Bone morphogenetic protein and retinoic acid synergistically specify female germ-cell fate in mice. EMBO J. 2017;36:3100-3119 pubmed publisher
Casey A, Daish T, Barbero J, Grützner F. Differential cohesin loading marks paired and unpaired regions of platypus sex chromosomes at prophase I. Sci Rep. 2017;7:4217 pubmed publisher
Xu L, Lu Y, Han D, Yao R, Wang H, Zhong S, et al. Rnf138 deficiency promotes apoptosis of spermatogonia in juvenile male mice. Cell Death Dis. 2017;8:e2795 pubmed publisher
Faisal I, Kauppi L. Reduced MAD2 levels dampen the apoptotic response to non-exchange sex chromosomes and lead to sperm aneuploidy. Development. 2017;144:1988-1996 pubmed publisher
Dai J, Voloshin O, Potapova S, Camerini Otero R. Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis. Cell Rep. 2017;18:1383-1394 pubmed publisher
Taylor L, Carlson D, Nandi S, Sherman A, Fahrenkrug S, McGrew M. Efficient TALEN-mediated gene targeting of chicken primordial germ cells. Development. 2017;144:928-934 pubmed publisher
Jordan P, Eyster C, Chen J, Pezza R, Rankin S. Sororin is enriched at the central region of synapsed meiotic chromosomes. Chromosome Res. 2017;25:115-128 pubmed publisher
Hanna R, Moffett D, Forster F, Trudgett A, Brennan G, Fairweather I. Fasciola hepatica: a light and electron microscope study of the ovary and of the development of oocytes within eggs in the uterus provides an insight into reproductive strategy. Vet Parasitol. 2016;221:93-103 pubmed publisher
Davies B, Hatton E, Altemose N, Hussin J, Pratto F, Zhang G, et al. Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice. Nature. 2016;530:171-176 pubmed publisher
Daish T, Casey A, Grützner F. Lack of sex chromosome specific meiotic silencing in platypus reveals origin of MSCI in therian mammals. BMC Biol. 2015;13:106 pubmed publisher
Kent T, Arnold S, Fasnacht R, Rowsey R, Mitchell D, Hogarth C, et al. ALDH Enzyme Expression Is Independent of the Spermatogenic Cycle, and Their Inhibition Causes Misregulation of Murine Spermatogenic Processes. Biol Reprod. 2016;94:12 pubmed publisher
Faisal I, Kauppi L. Sex chromosome recombination failure, apoptosis, and fertility in male mice. Chromosoma. 2016;125:227-35 pubmed publisher
Lambrot R, Lafleur C, Kimmins S. The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors. FASEB J. 2015;29:4402-16 pubmed publisher
Casey A, Daish T, Grützner F. Identification and characterisation of synaptonemal complex genes in monotremes. Gene. 2015;567:146-53 pubmed publisher
Sun F, Fujiwara Y, Reinholdt L, Hu J, Saxl R, Baker C, et al. Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis. Chromosoma. 2015;124:397-415 pubmed publisher
Fujiwara Y, Matsumoto H, Akiyama K, Srivastava A, Chikushi M, Ann Handel M, et al. An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility. Reproduction. 2015;149:67-74 pubmed publisher
product information
master code :
NB300-229
SKU :
NB300-229
product name :
SCP1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SCP1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SCP1. This antibody reacts with chicken,human,human (negative),mammal,monkey,mouse,parasite,primate - macaca mulatta (rhesus macaque),rat. The SCP1 Antibody - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Chemotaxis,IF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Immunohistochemistry-Frozen,Simple Western,Chromatin Immunoprecipitation (ChIP).
target :
SCP1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to the C-terminus of the mouse SCP1 protein sequence. [UniProt# Q62209]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Chicken,Human,Human (Negative),Mammal,Monkey,Mouse,Parasite,Primate - Macaca mulatta (Rhesus Macaque),Rat
gene symbol :
SYCP1
applications :
Immunocytochemistry/ Immunofluorescence,Chemotaxis,IF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Immunohistochemistry-Frozen,Simple Western,Chromatin Immunoprecipitation (ChIP)
USD :
409 USD
alt names :
Cancer/testis antigen 8, CT8MGC104417, HOM-TES-14, SCP1SCP-1, synaptonemal complex protein 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.