| Published Application/Species/Sample/Dilution | Reference |
|---|
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- immunoprecipitation; rat
- western blot; rat
| Deb I, Manhas N, Poddar R, Rajagopal S, Allan A, Lombroso P, et al. Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. J Neurosci. 2013;33:17814-26 pubmed publisher |
| Kim H, Kim Y, Jang J, Choi Y, Baek J, Hong J, et al. Neuroprotective effects of Polygonum multiflorum extract against glutamate-induced oxidative toxicity in HT22 hippocampal cells. J Ethnopharmacol. 2013;150:108-15 pubmed publisher |
| Sun W, Zelek Molik A, McGinty J. Short and long access to cocaine self-administration activates tyrosine phosphatase STEP and attenuates GluN expression but differentially regulates GluA expression in the prefrontal cortex. Psychopharmacology (Berl). 2013;229:603-13 pubmed publisher |
| Davis M, Olausson P, Greengard P, Taylor J, Nairn A. Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits. Eur J Neurosci. 2012;35:300-8 pubmed publisher |
| Poddar R, Deb I, Mukherjee S, Paul S. NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death. J Neurochem. 2010;115:1350-62 pubmed publisher |
- immunoprecipitation; mouse
- western blot; mouse
| Zhang Y, Kurup P, Xu J, Carty N, Fernandez S, Nygaard H, et al. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2010;107:19014-9 pubmed publisher |
- immunocytochemistry; mouse
| DiRocco D, Scheiner Z, Sindreu C, Chan G, Storm D. A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization. J Neurosci. 2009;29:2393-403 pubmed publisher |
- immunohistochemistry; mouse
- western blot; mouse
- immunohistochemistry; rat
- western blot; rat
| Zhang Y, Venkitaramani D, Gladding C, Zhang Y, Kurup P, Molnar E, et al. The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. J Neurosci. 2008;28:10561-6 pubmed publisher |
- immunohistochemistry - frozen section; rat
- western blot; rat
| Hu Y, Zhang Y, Venkitaramani D, Lombroso P. Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation. J Neurochem. 2007;103:531-41 pubmed |
- immunohistochemistry; mouse
| Choi Y, Lin S, Lee B, Kurup P, Cho H, Naegele J, et al. Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase. J Neurosci. 2007;27:2999-3009 pubmed |
- immunoprecipitation; rat
- western blot; rat
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- immunohistochemistry - frozen section; rat
- western blot; rat
| Bult A, Zhao F, Dirkx R, Sharma E, Lukacsi E, Solimena M, et al. STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum. J Neurosci. 1996;16:7821-31 pubmed |
| Paramasivam P, Choi S, Poddar R, Paul S. Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition. J Neuroinflammation. 2024;21:271 pubmed publisher |
| He R, Li L, Liu L, Ma Y, Fan S, Liu L, et al. Ceftriaxone improves impairments in synaptic plasticity and cognitive behavior in APP/PS1 mouse model of Alzheimer's disease by inhibiting extrasynaptic NMDAR-STEP61 signaling. J Neurochem. 2023;166:215-232 pubmed publisher |
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| Rajagopal S, Yang C, Demars K, Poddar R, Candelario Jalil E, Paul S. Regulation of post-ischemic inflammatory response: A novel function of the neuronal tyrosine phosphatase STEP. Brain Behav Immun. 2021;93:141-155 pubmed publisher |
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| Kim H, Lee G, Bhattarai K, Lee M, Back S, Kim H, et al. TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium. Autophagy. 2020;:1-18 pubmed publisher |
| Wang C, Li Y, Wu X, Tian H, Jiang S, Xu T, et al. IRF3 and IRF7 contribute to diesel exhaust particles-induced pulmonary inflammation by mediating mTORC1 activation and restraining autophagy in mice. Eur J Immunol. 2020;: pubmed publisher |
| Zheng J, Akbari M, Schirmer C, Reynaert M, Loyens A, Lefebvre B, et al. Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy. Acta Neuropathol Commun. 2020;8:25 pubmed publisher |
| Vincent G, Novak E, Siow V, Cunningham K, Griffith B, Comerford T, et al. Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation. Antioxid Redox Signal. 2020;33:1-19 pubmed publisher |
| Hu P, Liu J, Maita I, Kwok C, Gu E, Gergues M, et al. Chronic Stress Induces Maladaptive Behaviors by Activating Corticotropin-Releasing Hormone Signaling in the Mouse Oval Bed Nucleus of the Stria Terminalis. J Neurosci. 2020;40:2519-2537 pubmed publisher |
| Zhou W, Fang C, Zhang L, Wang Q, Li D, Zhu D. Thioredoxin domain-containing protein 9 (TXNDC9) contributes to oxaliplatin resistance through regulation of autophagy-apoptosis in colorectal adenocarcinoma. Biochem Biophys Res Commun. 2020;524:582-588 pubmed publisher |
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| Yoon J, Lee K, Seok J, Cheng W, Kwon H, Jeong C, et al. Zearalenone Induces Endoplasmic Reticulum Stress and Modulates the Expression of Phase I/II Enzymes in Human Liver Cells. Toxins (Basel). 2019;12: pubmed publisher |
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| Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, et al. C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy. 2019;:1-16 pubmed publisher |
| Zheng Z, Zhou Y, Ye L, Lu Q, Zhang K, Zhang J, et al. Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury. Exp Neurol. 2020;324:113138 pubmed publisher |
| Yu Y, Xiang N, Lin M, Huang J, Zhang J, Cheng B, et al. miR- 26a Sensitizes Melanoma Cells To Dabrafenib Via Targeting HMGB1-Dependent Autophagy Pathways. Drug Des Devel Ther. 2019;13:3717-3726 pubmed publisher |
| Codina Martínez H, Fernandez Garcia B, Díez Planelles C, Fernández A, Higarza S, Fernández Sanjurjo M, et al. Autophagy is required for performance adaptive response to resistance training and exercise-induced adult neurogenesis. Scand J Med Sci Sports. 2020;30:238-253 pubmed publisher |
| Wang R, Wang W, Li A, Wang Y, Jin J, Huang Z, et al. Lipopolysaccharide enhances DNA-induced IFN-β expression and autophagy by upregulating cGAS expression in A549 cells. Exp Ther Med. 2019;18:4157-4164 pubmed publisher |
| Zhang Y, Pan N, Sheng Y, Zhou M, Wen Z, Chen Y, et al. Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes. Immunol Lett. 2019;216:36-42 pubmed publisher |
| Frendo Cumbo S, Jaldin Fincati J, Coyaud E, Laurent E, Townsend L, Tan J, et al. Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation. J Biol Chem. 2019;294:16172-16185 pubmed publisher |
| Hong J, Kim J, Kim H, Lee W, Hwang Y. SB365, Pulsatilla Saponin D Induces Caspase-Independent Cell Death and Augments the Anticancer Effect of Temozolomide in Glioblastoma Multiforme Cells. Molecules. 2019;24: pubmed publisher |
| Dhandapani P, Begines Moreno I, Brea Calvo G, Gärtner U, Graeber T, Javier Sanchez G, et al. Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy. Sci Rep. 2019;9:12741 pubmed publisher |
| Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed publisher |
| Schott M, Weller S, Schulze R, Krueger E, Drizyte Miller K, Casey C, et al. Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes. J Cell Biol. 2019;218:3320-3335 pubmed publisher |
| Parejo S, Tschan M, Muraro M, Garattini E, Spagnoli G, Schläfli A. Assessing Autophagy During Retinoid Treatment of Breast Cancer Cells. Methods Mol Biol. 2019;2019:237-256 pubmed publisher |
| Geng J, Liu J, Yuan X, Liu W, Guo W. Andrographolide triggers autophagy-mediated inflammation inhibition and attenuates chronic unpredictable mild stress (CUMS)-induced depressive-like behavior in mice. Toxicol Appl Pharmacol. 2019;379:114688 pubmed publisher |
| Kang S, Son S, Baik S, Yang J, Mook Jung I. Autophagy-mediated secretory pathway is responsible for both normal and pathological tau in neurons. J Alzheimers Dis. 2019;: pubmed publisher |
| Cousin M, Conboy E, Wang J, Lenz D, Schwab T, Williams M, et al. RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal Abnormalities. Am J Hum Genet. 2019;: pubmed publisher |
| Malvin N, Kern J, Liu T, Brody S, Stappenbeck T. Autophagy proteins are required for club cell structure and function in airways. Am J Physiol Lung Cell Mol Physiol. 2019;317:L259-L270 pubmed publisher |
| Capurro M, Greenfield L, Prashar A, Xia S, Abdullah M, Wong H, et al. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nat Microbiol. 2019;: pubmed publisher |
| Ota K, Okuma T, Lorenzo A, Yokota A, Hino H, Kazama H, et al. Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest. Oncol Rep. 2019;42:231-242 pubmed publisher |
| Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed publisher |
| Lee D, Ahn J, Jang Y, Ha T, Jung C. Oleic acid-induced defective autolysosome shows impaired lipid degradation. Biochem Biophys Res Commun. 2019;513:553-559 pubmed publisher |
| Audesse A, Dhakal S, Hassell L, Gardell Z, Nemtsova Y, Webb A. FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells. PLoS Genet. 2019;15:e1008097 pubmed publisher |
| Im E, Lee C, Moon P, Rangaswamy G, Lee B, Lee J, et al. Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A. Nat Commun. 2019;10:1387 pubmed publisher |
| Bhatt V, Khayati K, Hu Z, Lee A, Kamran W, Su X, et al. Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis. Genes Dev. 2019;33:150-165 pubmed publisher |
| van der Kant R, Langness V, Herrera C, Williams D, Fong L, Leestemaker Y, et al. Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons. Cell Stem Cell. 2019;24:363-375.e9 pubmed publisher |
| Das L, Binko A, Traylor Z, Peng H, Lu K. Vitamin D improves sunburns by increasing autophagy in M2 macrophages. Autophagy. 2019;15:813-826 pubmed publisher |
| Twomey J, Zhang B. Circulating Tumor Cells Develop Resistance to TRAIL-Induced Apoptosis Through Autophagic Removal of Death Receptor 5: Evidence from an In Vitro Model. Cancers (Basel). 2019;11: pubmed publisher |
| Wang D, Xu Q, Yuan Q, Jia M, Niu H, Liu X, et al. Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab. Oncogene. 2019;38:3458-3474 pubmed publisher |
| Saladini S, Aventaggiato M, Barreca F, Morgante E, Sansone L, Russo M, et al. Metformin Impairs Glutamine Metabolism and Autophagy in Tumour Cells. Cells. 2019;8: pubmed publisher |
| Abdullah M, Greenfield L, Bronte Tinkew D, Capurro M, Rizzuti D, Jones N. VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Sci Rep. 2019;9:38 pubmed publisher |
| Ji E, Kim C, Kang H, Ahn S, Jung M, Hong Y, et al. RNA Binding Protein HuR Promotes Autophagosome Formation by Regulating Expression of Autophagy-Related Proteins 5, 12, and 16 in Human Hepatocellular Carcinoma Cells. Mol Cell Biol. 2019;39: pubmed publisher |
| Chou L, Cheng Y, Hsieh C, Lin C, Yang H, Chen Y, et al. Effect of Trehalose Supplementation on Autophagy and Cystogenesis in a Mouse Model of Polycystic Kidney Disease. Nutrients. 2018;11: pubmed publisher |
| Evans C, Thomas R, Freeman T, Hvoslef Eide M, Good M, Kidd E. Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice. Neurobiol Aging. 2019;75:136-149 pubmed publisher |
| Spinello I, Saulle E, Quaranta M, Pasquini L, Pelosi E, Castelli G, et al. The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells. Haematologica. 2019;104:973-985 pubmed publisher |
| Latre De Late P, Haidar M, Ansari H, Tajeri S, Szarka E, Alexa A, et al. Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104. Cell Microbiol. 2019;21:e12973 pubmed publisher |
| Giuliani A, Cirilli I, Prattichizzo F, Mensà E, Fulgenzi G, Sabbatinelli J, et al. The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells. Aging (Albany NY). 2018;10:2855-2873 pubmed publisher |
| Wang C, Bauckman K, Ross A, Symington J, Ligon M, Scholtes G, et al. A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence. Autophagy. 2019;15:527-542 pubmed publisher |
| Nawas A, Mistry R, Narayanan S, Thomas Jardin S, Ramachandran J, Ravichandran J, et al. IL-1 induces p62/SQSTM1 and autophagy in ERα+ /PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα- /PR- BCa-like phenotype. J Cell Biochem. 2018;: pubmed publisher |
| Zhu Y, Fang J, Wang H, Fei M, Tang T, Liu K, et al. Baicalin suppresses proliferation, migration, and invasion in human glioblastoma cells via Ca2+-dependent pathway. Drug Des Devel Ther. 2018;12:3247-3261 pubmed publisher |
| Janssen A, Katrukha E, van Straaten W, Verlhac P, Reggiori F, Kapitein L. Probing aggrephagy using chemically-induced protein aggregates. Nat Commun. 2018;9:4245 pubmed publisher |
| Janser F, Adams O, Bütler V, Schläfli A, Dislich B, Seiler C, et al. Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells. Int J Mol Sci. 2018;19: pubmed publisher |
| Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, et al. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. Autophagy. 2018;:1-17 pubmed publisher |
| Li H, Ham A, Ma T, Kuo S, Kanter E, Kim D, et al. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy. 2019;15:113-130 pubmed publisher |
| Dias B, de Souza C, Almeida N, Lima J, Fukutani K, Dos Santos T, et al. Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages. Front Microbiol. 2018;9:1890 pubmed publisher |
| Tsai Y, Wen Y, Wang J, Yang K, Sun H, Liou J, et al. Complement regulatory protein CD46 induces autophagy against oxidative stress-mediated apoptosis in normal and asthmatic airway epithelium. Sci Rep. 2018;8:12973 pubmed publisher |
| Langer R, Neppl C, Keller M, Schmid R, Tschan M, Berezowska S. Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers (Basel). 2018;10: pubmed publisher |
| Aubert P, Oleynikova E, Rizvi H, Ndjim M, Le Berre Scoul C, Grohard P, et al. Maternal protein restriction induces gastrointestinal dysfunction and enteric nervous system remodeling in rat offspring. FASEB J. 2019;33:770-781 pubmed publisher |
| Hutt D, Mishra S, Roth D, Larsen M, Anglès F, Frizzell R, et al. Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy. J Biol Chem. 2018;293:13682-13695 pubmed publisher |
| Mauthe M, Orhon I, Rocchi C, Zhou X, Luhr M, Hijlkema K, et al. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Autophagy. 2018;14:1435-1455 pubmed publisher |
| Corona Velazquez A, Corona A, Klein K, Jackson W. Poliovirus induces autophagic signaling independent of the ULK1 complex. Autophagy. 2018;14:1201-1213 pubmed publisher |
| Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher |
| Adams O, Janser F, Dislich B, Berezowska S, Humbert M, Seiler C, et al. A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE. 2018;13:e0197610 pubmed publisher |
| Gao R, Ma J, Wen Z, Yang P, Zhao J, Xue M, et al. Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils. Oncoimmunology. 2018;7:e1438108 pubmed publisher |
| Lapierre J, Rodriguez M, Ojha C, El Hage N. Critical Role of Beclin1 in HIV Tat and Morphine-Induced Inflammation and Calcium Release in Glial Cells from Autophagy Deficient Mouse. J Neuroimmune Pharmacol. 2018;13:355-370 pubmed publisher |
| Jin J, Britschgi A, Schläfli A, Humbert M, Shan Krauer D, Batliner J, et al. Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxid Med Cell Longev. 2018;2018:1482795 pubmed publisher |
| Lundquist M, Goncalves M, Loughran R, Possik E, Vijayaraghavan T, Yang A, et al. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Mol Cell. 2018;70:531-544.e9 pubmed publisher |
| Shukla S, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, et al. Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell. 2018;173:624-633.e8 pubmed publisher |
| Carvajal F, Mira R, Rovegno M, Minniti A, Cerpa W. Age-related NMDA signaling alterations in SOD2 deficient mice. Biochim Biophys Acta Mol Basis Dis. 2018;1864:2010-2020 pubmed publisher |
| Saito Y, Moriya S, Kazama H, Hirasawa K, Miyahara K, Kokuba H, et al. Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis. Int J Oncol. 2018;52:1165-1177 pubmed publisher |
| Yang J, Wang C, Su C, Ho H, Chang C, Chou C, et al. Eudesmin attenuates Helicobacter pylori-induced epithelial autophagy and apoptosis and leads to eradication of H. pylori infection. Exp Ther Med. 2018;15:2388-2396 pubmed publisher |
| Santiago O Farrill J, Kleinerman E, Hollomon M, Livingston A, Wang W, Tsai J, et al. Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy. Oncotarget. 2018;9:1602-1616 pubmed publisher |
| Tao L, Togarrati P, Choi K, Suknuntha K. StemRegenin 1 selectively promotes expansion of Multipotent Hematopoietic Progenitors derived from Human Embryonic Stem Cells. J Stem Cells Regen Med. 2017;13:75-79 pubmed |
| Chao T, Wang T, Lee C, Yiin S, Ho C, Wu S, et al. Anti-Cancerous Effect of Inonotus taiwanensis Polysaccharide Extract on Human Acute Monocytic Leukemia Cells through ROS-Independent Intrinsic Mitochondrial Pathway. Int J Mol Sci. 2018;19: pubmed publisher |
| Li Y, Guo X, Hu C, Du Y, Guo C, Di Wang -, et al. Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection. Cell Death Differ. 2018;25:1304-1318 pubmed publisher |
| Yang A, Herter Sprie G, Zhang H, Lin E, Biancur D, Wang X, et al. Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. 2018;8:276-287 pubmed publisher |
| Pose Utrilla J, Garcia Guerra L, del Puerto A, Martin A, Jurado Arjona J, De León Reyes N, et al. Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1. Nat Commun. 2017;8:2275 pubmed publisher |
| Sanborn R, Ross H, Aung S, Acheson A, Moudgil T, Puri S, et al. A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer. J Immunother Cancer. 2017;5:103 pubmed publisher |
| Magnaghi P, Salom B, Cozzi L, Amboldi N, Ballinari D, Tamborini E, et al. Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury. Mol Cancer Ther. 2018;17:603-613 pubmed publisher |
| Garcia Peterson L, Ndiaye M, Singh C, Chhabra G, Huang W, Ahmad N. SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. Genes Cancer. 2017;8:701-712 pubmed publisher |
| Knock E, Matsuzaki S, Takamura H, Satoh K, Rooke G, Han K, et al. SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model. Neurobiol Dis. 2018;110:154-165 pubmed publisher |
| Pascarella A, Terracciano C, Farina O, Lombardi L, Esposito T, Napolitano F, et al. Vacuolated PAS-positive lymphocytes as an hallmark of Pompe disease and other myopathies related to impaired autophagy. J Cell Physiol. 2017;: pubmed publisher |
| Persaud A, Cormerais Y, Pouyssegur J, Rotin D. Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin. J Cell Sci. 2018;131: pubmed publisher |
| Zhou H, Luo W, Zeng C, Zhang Y, Wang L, Yao W, et al. PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines. Oncotarget. 2017;8:80770-80789 pubmed publisher |
| Liu Y, Wang L, Xu T, Guo X, Li Y, Yin T, et al. Whole-genome sequencing of African dogs provides insights into adaptations against tropical parasites. Mol Biol Evol. 2017;: pubmed publisher |
| Humbert M, Federzoni E, Tschan M. Distinct TP73-DAPK2-ATG5 pathway involvement in ATO-mediated cell death versus ATRA-mediated autophagy responses in APL. J Leukoc Biol. 2017;: pubmed publisher |
| Parcon P, Balasubramaniam M, Ayyadevara S, Jones R, Liu L, Shmookler Reis R, et al. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs. Alzheimers Dement. 2018;14:230-242 pubmed publisher |
| Kemp V, Dautzenberg I, Limpens R, van den Wollenberg D, Hoeben R. Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. Viruses. 2017;9: pubmed publisher |
| Muniz Feliciano L, Doggett T, Zhou Z, Ferguson T. RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye. Autophagy. 2017;13:2072-2085 pubmed publisher |
| Niklaus M, Adams O, Berezowska S, Zlobec I, Graber F, Slotta Huspenina J, et al. Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer. Oncotarget. 2017;8:54604-54615 pubmed publisher |
| Jiang P, Gan M, Yen S, McLean P, Dickson D. Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates. Sci Rep. 2017;7:7690 pubmed publisher |
| Jia J, Werkmeister E, Gonzalez Hilarion S, Leroy C, Gruenert D, Lafont F, et al. Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins. J Cell Sci. 2017;130:3009-3022 pubmed publisher |
| Wiedmer T, Blank A, Pantasis S, Normand L, Bill R, Krebs P, et al. Autophagy Inhibition Improves Sunitinib Efficacy in Pancreatic Neuroendocrine Tumors via a Lysosome-dependent Mechanism. Mol Cancer Ther. 2017;16:2502-2515 pubmed publisher |
| Germic N, Stojkov D, Oberson K, Yousefi S, Simon H. Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology. 2017;152:517-525 pubmed publisher |
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