product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GABA-A R beta 3 Antibody - Azide Free
catalog :
NB300-199
quantity :
0.1 ml (also 0.02 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 10
Reference
Wang G, Peng S, Reyes Mendez M, Keramidas A, Castellano D, Wu K, et al. The TMEM132B-GABAA receptor complex controls alcohol actions in the brain. Cell. 2024;187:6649-6668.e35 pubmed publisher
Nwosu G, Shen W, Zavalin K, Poliquin S, Randhave K, Flamm C, et al. GABAA Receptor β3 Subunit Mutation N328D Heterozygous Knock-in Mice Have Lennox-Gastaut Syndrome. Int J Mol Sci. 2023;24: pubmed publisher
Hernandez C, Shen Y, Hu N, Shen W, Narayanan V, Ramsey K, et al. GABRG2 Variants Associated with Febrile Seizures. Biomolecules. 2023;13: pubmed publisher
Michalettos G, Walter H, Antunes A, Wieloch T, Talhada D, Ruscher K. Effect of Anti-inflammatory Treatment with AMD3100 and CX3CR1 Deficiency on GABAA Receptor Subunit and Expression of Glutamate Decarboxylase Isoforms After Stroke. Mol Neurobiol. 2021;58:5876-5889 pubmed publisher
Hernandez C, Tian X, Hu N, Shen W, Catron M, Yang Y, et al. Dravet syndrome-associated mutations in GABRA1, GABRB2 and GABRG2 define the genetic landscape of defects of GABAA receptors. Brain Commun. 2021;3:fcab033 pubmed publisher
Chen M, Chen Y, Huo Q, Wang L, Tan S, Misrani A, et al. Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models. Mol Neurodegener. 2021;16:14 pubmed publisher
Qu S, Zhou C, Howe R, Shen W, Huang X, Catron M, et al. The K328M substitution in the human GABAA receptor gamma2 subunit causes GEFS+ and premature sudden death in knock-in mice. Neurobiol Dis. 2021;152:105296 pubmed publisher
Qu S, Catron M, Zhou C, Janve V, Shen W, Howe R, et al. GABAA receptor β3 subunit mutation D120N causes Lennox-Gastaut syndrome in knock-in mice. Brain Commun. 2020;2:fcaa028 pubmed publisher
Bocker H, Heinrich T, Liebmann L, Hennings J, Seemann E, Gerth M, et al. The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release. Cereb Cortex. 2019;29:4263-4276 pubmed publisher
Lü C, Liu D, Jiang H, Pan F, Ho C, Ho R. Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain. Neural Plast. 2017;2017:5715816 pubmed publisher
product information
master code :
NB300-199
SKU :
NB300-199
product name :
GABA-A R beta 3 Antibody - Azide Free
unit size :
0.1 ml (also 0.02 ml)
description :
The GABA-A R beta 3 Antibody - Azide Free from Novus is a rabbit polyclonal antibody to GABA-A R beta 3. This antibody reacts with human,mouse,rat. The GABA-A R beta 3 Antibody - Azide Free has been validated for the following applications: Simple Western,IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
GABA-A R beta 3
category :
Primary Antibodies
buffer :
10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/ml BSA, 50% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Fusion protein from the cytoplasmic loop of the beta 3 subunit. Accession # P63079
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Specific for the ~53 kDa beta 3-subunit of the GABAA receptor in Western blots
theoretical molecular weight :
53 kDa
gene symbol :
GABRB3
accessionNumbers :
P63079
applications :
Simple Western,IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
ECA5, GABA(A) receptor beta-3 subunit, GABA(A) receptor subunit beta-3, GABAA receptor beta-3 subunit, GABA-alpha receptor beta-2 subunit, gamma-aminobutyric acid (GABA) A receptor, beta 3, gamma-aminobutyric acid receptor subunit beta-3, MGC9051
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.