GABA-AR alpha 6 Antibody - Azide Free | Novus Biologicals NB300-196 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

GABA-AR alpha 6 Antibody - Azide Free

catalog :

NB300-196

quantity :

0.1 ml

price :

399 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

MANDRA1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Novus Biologicals product webpage

citations: 5

Reference
Huang T, Lin Y, Hsiao C, Wang L, Ajibola M, Abdulmajeed W, et al. Differential expression of GABAA receptor subunits δ and α6 mediates tonic inhibition in parvalbumin and somatostatin interneurons in the mouse hippocampus. Front Cell Neurosci. 2023;17:1146278 pubmed publisher
Tzeng H, Lee M, Fan P, Knutson D, Lai T, Sieghart W, et al. α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia. Neurotherapeutics. 2020;: pubmed publisher
Stay T, Miterko L, Arancillo M, Lin T, Sillitoe R. In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. Dis Model Mech. 2019;13: pubmed publisher
Fan P, Lai T, Hor C, Lee M, Huang P, Sieghart W, et al. The α6 subunit-containing GABAA receptor: A novel drug target for inhibition of trigeminal activation. Neuropharmacology. 2018;140:1-13 pubmed publisher
Annese T, Corsi P, Ruggieri S, Tamma R, Marinaccio C, Picocci S, et al. Isolation and characterization of neural stem cells from dystrophic mdx mouse. Exp Cell Res. 2016;343:190-207 pubmed publisher

product information

master code :

NB300-196

SKU :

NB300-196

product name :

GABA-AR alpha 6 Antibody - Azide Free

unit size :

0.1 ml

description :

The GABA-AR alpha 6 Antibody - Azide Free from Novus is a rabbit polyclonal antibody to GABA-AR alpha 6. This antibody reacts with human,mouse,rat. The GABA-AR alpha 6 Antibody - Azide Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry,Western Blot,Knockout Validated.

target :

GABA-AR alpha 6

category :

Primary Antibodies

buffer :

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Fusion protein from the cytoplasmic loop of the alpha 6 subunit. Accession # P30191

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Specific for endogenous levels of the ~57 kDa alpha 6-subunit of the GABAA receptor

theoretical molecular weight :

57 kDa

gene symbol :

GABRA6

Antibody validation :

Knockout/Knockdown

accessionNumbers :

P30191

applications :

Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry,Western Blot,Knockout Validated

USD :

399 USD

alt names :

GABA subunit A receptor alpha 6, GABA(A) receptor subunit alpha-6, gamma-aminobutyric acid (GABA) A receptor, alpha 6, gamma-aminobutyric acid receptor subunit alpha-6, MGC116903, MGC116904

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage