product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GABA-A R gamma 2 Antibody - Azide Free
catalog :
NB300-190
quantity :
0.1 ml
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 14
Reference
Chan E, Ge Y, So Y, Bai Y, Liu L, Wang Y. Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis. Cell Rep. 2022;41:111584 pubmed publisher
Janach G, Böhm M, Döhne N, Kim H, Rosario M, Strauss U. Interferon-γ enhances neocortical synaptic inhibition by promoting membrane association and phosphorylation of GABAA receptors in a protein kinase C-dependent manner. Brain Behav Immun. 2022;101:153-164 pubmed publisher
He Y, Cai X, Liu H, Conde K, Xu P, Li Y, et al. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Mol Psychiatry. 2021;: pubmed publisher
Kim E, Xu Y, Cassidy R, Lu Y, Yang Y, Tian J, et al. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun. 2020;11:3794 pubmed publisher
Singh K, Gupta A, Sarkar A, Gupta I, Rana S, Sarkar S, et al. Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway. Sci Rep. 2020;10:598 pubmed publisher
Shimell J, Shah B, Cain S, Thouta S, Kuhlmann N, Tatarnikov I, et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep. 2019;29:2422-2437.e8 pubmed publisher
Zhang Q, Tran T, Wang M, Ranek M, Kokkonen Simon K, Gao J, et al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nat Commun. 2018;9:5230 pubmed publisher
Fan J, Li D, Chen H, Huang J, Xu J, Zhu W, et al. Metformin produces anxiolytic-like effects in rats by facilitating GABAA receptor trafficking to membrane. Br J Pharmacol. 2019;176:297-316 pubmed publisher
Das N, Carpenter A, Yoshida T, Kumar S, Gautam S, Mostany R, et al. TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart. J Mol Cell Cardiol. 2018;121:107-123 pubmed publisher
Yariswamy M, Yoshida T, Valente A, Kandikattu H, Sakamuri S, Siddesha J, et al. Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction. J Biol Chem. 2016;291:19425-36 pubmed publisher
Huang S, Hokenson K, Bandyopadhyay S, Russek S, Kirkwood A. Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex. J Neurosci. 2015;35:15916-20 pubmed publisher
Johnson A, Nagle K, Tremble S, Cipolla M. The Contribution of Normal Pregnancy to Eclampsia. PLoS ONE. 2015;10:e0133953 pubmed publisher
Somanna N, Yariswamy M, Garagliano J, Siebenlist U, Mummidi S, Valente A, et al. Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2. Cell Signal. 2015;27:1928-38 pubmed publisher
Wu Z, Kim E, Sun H, Xu Y, Mangieri L, Li D, et al. GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. J Neurosci. 2015;35:3312-8 pubmed publisher
product information
master code :
NB300-190
SKU :
NB300-190
product name :
GABA-A R gamma 2 Antibody - Azide Free
unit size :
0.1 ml
description :
The GABA-A R gamma 2 Antibody - Azide Free from Novus is a rabbit polyclonal antibody to GABA-A R gamma 2. This antibody reacts with human,mouse,rat. The GABA-A R gamma 2 Antibody - Azide Free has been validated for the following applications: IF/IHC,Western Blot,Knockdown Validated,Immunohistochemistry.
target :
GABA-A R gamma 2
category :
Primary Antibodies
buffer :
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Fusion protein from the cytoplasmic loop of the gamma 2 subunit. Accession # P18508
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Specific for endogenous levels of the ~46 kDa gamma 2-subunit of the GABAA receptor
theoretical molecular weight :
46 kDa
gene symbol :
GABRG2
accessionNumbers :
P18508
applications :
IF/IHC,Western Blot,Knockdown Validated,Immunohistochemistry
USD :
409 USD
alt names :
CAE2, ECA2, GABA(A) receptor subunit gamma-2, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid receptor subunit gamma-2, GEFSP3
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.