product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Sodium Potassium ATPase Alpha 1 Antibody (464.6) - BSA Free
catalog :
NB300-146
quantity :
0.05 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
Alexa Fluor 594
clone name :
464.6
reactivity :
anurans, fruit fly , guinea-pigs, human, mouse, rat, dogs, bovine, pigs , brewer's yeast, domestic sheep, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 114
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 6d
Miwa T, Wei F, Tomizawa K. Cdk5 regulatory subunit-associated protein 1 knockout mice show hearing loss phenotypically similar to age-related hearing loss. Mol Brain. 2021;14:82 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4b
Miwa T. Protective Effects of N1-Methylnicotinamide Against High-Fat Diet- and Age-Induced Hearing Loss via Moderate Overexpression of Sirtuin 1 Protein. Front Cell Neurosci. 2021;15:634868 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 5A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2c
Lobato Álvarez J, Roldán M, López Murillo T, González Ramírez R, Bonilla Delgado J, Shoshani L. The Apical Localization of Na+, K+-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the ?2 Subunit. Front Physiol. 2016;7:450 pubmed
  • western blot; bovine; 1:5000; loading ...; tbl 2
Ontsouka C, Huang X, Aliyev E, Albrecht C. In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Mol Cell Endocrinol. 2017;439:35-45 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 1
Strazielle N, Creidy R, Malcus C, Boucraut J, Ghersi Egea J. T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium. PLoS ONE. 2016;11:e0150945 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig 9
Liu W, Edin F, Blom H, Magnusson P, Schrott Fischer A, Glueckert R, et al. Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man. Cell Tissue Res. 2016;365:13-27 pubmed publisher
  • western blot; mouse
Sütt S, Altpere A, Reimets R, Visnapuu T, Loomets M, Raud S, et al. Wfs1-deficient animals have brain-region-specific changes of Na+, K+-ATPase activity and mRNA expression of α1 and β1 subunits. J Neurosci Res. 2015;93:530-7 pubmed publisher
  • western blot; mouse
Ohtake N, Saito M, Eto M, Seki K. Exendin-4 promotes the membrane trafficking of the AMPA receptor GluR1 subunit and ADAM10 in the mouse neocortex. Regul Pept. 2014;190-191:1-11 pubmed publisher
  • western blot; mouse
Fan N, Sun H, Wang Y, Zhang L, Xia Z, Peng L, et al. Midkine, a potential link between obesity and insulin resistance. PLoS ONE. 2014;9:e88299 pubmed publisher
  • western blot; human
Wang Q, Schultz B. Cholera toxin enhances Na(+) absorption across MCF10A human mammary epithelia. Am J Physiol Cell Physiol. 2014;306:C471-84 pubmed publisher
  • western blot; human
Drivas T, Holzbaur E, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest. 2013;123:4525-39 pubmed publisher
  • western blot; human
Aggelis V, Craven R, Peng J, Harnden P, Schaffer L, Hernandez G, et al. VHL-dependent regulation of a ?-dystroglycan glycoform and glycogene expression in renal cancer. Int J Oncol. 2013;43:1368-76 pubmed publisher
  • western blot; rat
Ontawong A, Saowakon N, Vivithanaporn P, Pongchaidecha A, Lailerd N, Amornlerdpison D, et al. Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats. Biomed Res Int. 2013;2013:820786 pubmed publisher
  • immunocytochemistry; mouse
  • immunohistochemistry; mouse
Jang H, Han S, Kim J, Lee S, Lipschutz J, Park K. Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury. Biochim Biophys Acta. 2013;1832:1998-2008 pubmed publisher
  • western blot; rat
Schauer K, Freund D, Prenni J, Curthoys N. Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis. Am J Physiol Renal Physiol. 2013;305:F628-40 pubmed publisher
  • western blot; dogs
Raksaseri P, Chatsudthipong V, Muanprasat C, Soodvilai S. Activation of liver X receptors reduces CFTR-mediated Cl(-) transport in kidney collecting duct cells. Am J Physiol Renal Physiol. 2013;305:F583-91 pubmed publisher
  • western blot; human
Feduska J, Garcia P, Brennan S, Bu S, Council L, Yoon K. N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells. BMC Cancer. 2013;13:261 pubmed publisher
  • immunocytochemistry; domestic rabbit
  • immunocytochemistry; human
Hatou S, Higa K, Inagaki E, Yoshida S, Kimura E, Hayashi R, et al. Validation of Na,K-ATPase pump function of corneal endothelial cells for corneal regenerative medicine. Tissue Eng Part C Methods. 2013;19:901-10 pubmed publisher
  • western blot; fruit fly
Matta S, Van Kolen K, da Cunha R, van den Bogaart G, Mandemakers W, Miskiewicz K, et al. LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis. Neuron. 2012;75:1008-21 pubmed publisher
  • western blot; dogs
Le Goff A, Ji Z, Leclercq B, Bourette R, Mougel A, Guerardel C, et al. Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling. J Biol Chem. 2012;287:35382-96 pubmed publisher
  • immunocytochemistry; mouse
Shao H, Lee S, Gae Scott S, Nakata C, Chen S, Hamad A, et al. Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity. J Biol Chem. 2012;287:35860-72 pubmed publisher
  • western blot; mouse
Chun K, Araki K, Jee Y, Lee D, Oh B, Huang H, et al. Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization. Endocrinology. 2012;153:1649-62 pubmed publisher
  • western blot; rat
Larsson S, Resjö S, Gomez M, James P, Holm C. Characterization of the lipid droplet proteome of a clonal insulin-producing ?-cell line (INS-1 832/13). J Proteome Res. 2012;11:1264-73 pubmed publisher
  • western blot; pigs
Li H, Ganta S, Fong P. Altered ion transport by thyroid epithelia from CFTR(-/-) pigs suggests mechanisms for hypothyroidism in cystic fibrosis. Exp Physiol. 2010;95:1132-44 pubmed publisher
  • western blot; mouse
  • western blot; rat
  • western blot; human
Cottrell G, Padilla B, Amadesi S, Poole D, Murphy J, Hardt M, et al. Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling. J Biol Chem. 2009;284:22411-25 pubmed publisher
  • western blot; domestic sheep
Sironi C, Bodega F, Porta C, Monaco A, Zocchi L, Agostoni E. Na+-glucose cotransporter is also expressed in mesothelium of species with thick visceral pleura. Respir Physiol Neurobiol. 2008;161:261-6 pubmed publisher
  • western blot; domestic rabbit
Sironi C, Bodega F, Porta C, Zocchi L, Agostoni E. Expression of Na+-glucose cotransporter (SGLT1) in visceral and parietal mesothelium of rabbit pleura. Respir Physiol Neurobiol. 2007;159:68-75 pubmed
  • western blot; anurans
Perry J, Dembla Rajpal N, Hall L, Pritchard J. A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport. J Biol Chem. 2006;281:38071-9 pubmed
  • western blot; bovine
Shah M, Patel K, Sehgal P. Monocrotaline pyrrole-induced endothelial cell megalocytosis involves a Golgi blockade mechanism. Am J Physiol Cell Physiol. 2005;288:C850-62 pubmed
  • western blot; human
Wang J, Velotta J, McDonough A, Farley R. All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides. Am J Physiol Cell Physiol. 2001;281:C1336-43 pubmed
  • western blot; brewer's yeast
Farley R, Elquza E, Müller Ehmsen J, Kane D, Nagy A, Kasho V, et al. 18O-exchange evidence that mutations of arginine in a signature sequence for P-type pumps affect inorganic phosphate binding. Biochemistry. 2001;40:6361-70 pubmed
  • immunohistochemistry; guinea-pigs
  • immunohistochemistry; rat
McDonough A, Zhang Y, Shin V, Frank J. Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes. Am J Physiol. 1996;270:C1221-7 pubmed
Kuintzle R, Santat L, Elowitz M. Diversity in Notch ligand-receptor signaling interactions. elife. 2025;12: pubmed publisher
Wright S, Kumari P, Fraile xc1 greda V, Wang C, Shivcharan S, Kappelhoff S, et al. Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells. Cell. 2025;188:280-291.e17 pubmed publisher
Hou P, Zielonka M, Serneels L, Martínez Muriana A, Fattorelli N, Wolfs L, et al. The γ-secretase substrate proteome and its role in cell signaling regulation. Mol Cell. 2023;83:4106-4122.e10 pubmed publisher
Harich O, Gavriliuc O, Ordodi V, Tirziu A, Paunescu V, Panaitescu C, et al. In Vitro Study of the Multimodal Effect of Na+/K+ ATPase Blocker Ouabain on the Tumor Microenvironment and Malignant Cells. Biomedicines. 2023;11: pubmed publisher
Rah S, Joe Y, Park J, Ryter S, Park C, Chung H, et al. CD38/ADP-ribose/TRPM2-mediated nuclear Ca2+ signaling is essential for hepatic gluconeogenesis in fasting and diabetes. Exp Mol Med. 2023;55:1492-1505 pubmed publisher
van der Valk W, van Beelen E, Steinhart M, Nist Lund C, Osorio D, de Groot J, et al. A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs. Cell Rep. 2023;42:112623 pubmed publisher
Van Acker Z, Perdok A, Hellemans R, North K, Vorsters I, Cappel C, et al. Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism. Nat Commun. 2023;14:2847 pubmed publisher
Ta A, Ricci Azevedo R, Vasudevan S, Wright S, Kumari P, Havira M, et al. A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3. Nat Commun. 2023;14:2035 pubmed publisher
Paul D, Stern O, Vallis Y, Dhillon J, Buchanan A, McMahon H. Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis. Nat Commun. 2023;14:947 pubmed publisher
Wang Z, Yang X, Wang X, Liang F, Tang Y. Glycyrrhizin attenuates caspase-11-dependent immune responses and coagulopathy by targeting high mobility group box 1. Int Immunopharmacol. 2022;107:108713 pubmed publisher
Wong B, Mei D, Chua G, Galam D, Wenk M, Torta F, et al. The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis. J Biol Chem. 2022;298:101709 pubmed publisher
Cheng Y, Zhang T, Ma X, Pratuangtham S, Zhang G, Ondrus A, et al. A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes. Nat Chem Biol. 2021;17:1271-1280 pubmed publisher
Yoon S, Myczek K, Penzes P. cAMP Signaling-Mediated Phosphorylation of Diacylglycerol Lipase α Regulates Interaction With Ankyrin-G and Dendritic Spine Morphology. Biol Psychiatry. 2021;90:263-274 pubmed publisher
Wang X, Shi J, Li Z, Li L, Zhang R, Bai Y, et al. An 8-Hydroxy-Quinoline Derivative Protects Against Lipopolysaccharide-Induced Lethality in Endotoxemia by Inhibiting HMGB1-Mediated Caspase-11 Signaling. Front Pharmacol. 2021;12:673818 pubmed publisher
Kravtsova V, Paramonova I, Vilchinskaya N, Tishkova M, Matchkov V, Shenkman B, et al. Chronic Ouabain Prevents Na,K-ATPase Dysfunction and Targets AMPK and IL-6 in Disused Rat Soleus Muscle. Int J Mol Sci. 2021;22: pubmed publisher
Wang X, Li Z, Bai Y, Zhang R, Meng R, Chen F, et al. A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis. Cell Death Dis. 2021;12:402 pubmed publisher
Liu W, Luque M, Li H, Schrott Fischer A, Glueckert R, Tylstedt S, et al. Spike Generators and Cell Signaling in the Human Auditory Nerve: An Ultrastructural, Super-Resolution, and Gene Hybridization Study. Front Cell Neurosci. 2021;15:642211 pubmed publisher
O Connor C, Wallace Povirk A, Ning C, Frühauf J, Tong N, Gangjee A, et al. Folate transporter dynamics and therapy with classic and tumor-targeted antifolates. Sci Rep. 2021;11:6389 pubmed publisher
Tang Y, Wang X, Li Z, He Z, Yang X, Cheng X, et al. Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties. Immunity. 2021;54:454-467.e6 pubmed publisher
Yoon S, Piguel N, Khalatyan N, Dionisio L, Savas J, Penzes P. Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome. Mol Psychiatry. 2021;: pubmed publisher
van Beelen E, van der Valk W, de Groot J, Hensen E, Locher H, van Benthem P. Migration and fate of vestibular melanocytes during the development of the human inner ear. Dev Neurobiol. 2020;: pubmed publisher
Nordström C, Danckwardt Lillieström N, Liu W, Rask Andersen H. "Reversed polarization" of Na/K-ATPase-a sign of inverted transport in the human endolymphatic sac: a super-resolution structured illumination microscopy (SR-SIM) study. Cell Tissue Res. 2020;379:445-457 pubmed publisher
Liu W, Luque M, Glueckert R, Danckwardt Lillieström N, Nordström C, Schrott Fischer A, et al. Expression of Na/K-ATPase subunits in the human cochlea: a confocal and super-resolution microscopy study with special reference to auditory nerve excitation and cochlear implantation. Ups J Med Sci. 2019;124:168-179 pubmed publisher
O Banion C, Vickerman B, Haar L, Lawrence D. Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases. Cell Chem Biol. 2019;26:1393-1406.e7 pubmed publisher
Verma S, Prescott R, Cherayil B. The commensal bacterium Bacteroides fragilis down-regulates ferroportin expression and alters iron homeostasis in macrophages. J Leukoc Biol. 2019;106:1079-1088 pubmed publisher
Han K, Chang J, Azar D. MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells. Invest Ophthalmol Vis Sci. 2019;60:2321-2329 pubmed publisher
Rasiah P, Maddala R, Bennett V, Rao P. Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. Dev Biol. 2019;446:119-131 pubmed publisher
Yamashita K, Hatou S, Inagaki E, Higa K, Tsubota K, Shimmura S. A Rabbit Corneal Endothelial Dysfunction Model Using Endothelial-Mesenchymal Transformed Cells. Sci Rep. 2018;8:16868 pubmed publisher
Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, et al. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis. Immunity. 2018;49:740-753.e7 pubmed publisher
Saudrais E, Strazielle N, Ghersi Egea J. Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development. Am J Physiol Cell Physiol. 2018;315:C445-C456 pubmed publisher
Kong Y, Zhao L, Charette J, Hicks W, Stone L, Nishina P, et al. An FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency. Hum Mol Genet. 2018;27:3340-3352 pubmed publisher
Yamashita K, Inagaki E, Hatou S, Higa K, Ogawa A, Miyashita H, et al. Corneal endothelial regeneration using mesenchymal stem cell derived from human umbilical cord. Stem Cells Dev. 2018;: pubmed publisher
Kavanagh E, Lindsay S, Halasz M, Gubbins L, Weiner Gorzel K, Guang M, et al. Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells. Oncogenesis. 2017;6:e388 pubmed publisher
Liu W, Schrott Fischer A, Glueckert R, Benav H, Rask Andersen H. The Human "Cochlear Battery" - Claudin-11 Barrier and Ion Transport Proteins in the Lateral Wall of the Cochlea. Front Mol Neurosci. 2017;10:239 pubmed publisher
Wongwan T, Kittayaruksakul S, Asavapanumas N, Chatsudthipong V, Soodvilai S. Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells. Pflugers Arch. 2017;469:1471-1481 pubmed publisher
Uchida H, Machida M, Miura T, Kawasaki T, Okazaki T, Sasaki K, et al. A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells. JCI Insight. 2017;2:e86492 pubmed publisher
Sugio S, Tohyama K, Oku S, Fujiyoshi K, Yoshimura T, Hikishima K, et al. Astrocyte-mediated infantile-onset leukoencephalopathy mouse model. Glia. 2017;65:150-168 pubmed publisher
Paparelli L, Corthout N, Pavie B, Wakefield D, Sannerud R, Jovanovic Talisman T, et al. Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane. PLoS Comput Biol. 2016;12:e1005095 pubmed publisher
Jiang Y, Woosley A, Sivalingam N, Natarajan S, Howe P. Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-?-induced autophagy. Nat Cell Biol. 2016;18:851-63 pubmed publisher
Paparelli L, Corthout N, Pavie B, Annaert W, Munck S. Analyzing Protein Clusters on the Plasma Membrane: Application of Spatial Statistical Analysis Methods on Super-Resolution Microscopy Images. Adv Anat Embryol Cell Biol. 2016;219:95-122 pubmed publisher
Jang C, Oh S, Wada S, Rowe G, Liu L, Chan M, et al. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016;22:421-6 pubmed publisher
Luo K, Thaete L, Neerhof M. Endothelin Receptor A Antagonism and Fetal Growth in Endothelial Nitric Oxide Synthase Gene Knockout Maternal and Fetal Mice. Reprod Sci. 2016;23:1028-36 pubmed publisher
Tokuda S, Kim Y, Matsumoto H, Muro S, Hirai T, Mishima M, et al. Effects of Hydrostatic Pressure on Carcinogenic Properties of Epithelia. PLoS ONE. 2015;10:e0145522 pubmed publisher
Yan Q, Tang S, Tan Z, Han X, Zhou C, Kang J, et al. Proteomic Analysis of Isolated Plasma Membrane Fractions from the Mammary Gland in Lactating Cows. J Agric Food Chem. 2015;63:7388-98 pubmed publisher
Huang B, Wang D, Deng W. Protective effects of dexamethasone on early acute lung injury induced by oleic acid in rats. Int J Clin Exp Med. 2014;7:4698-709 pubmed
Yoon H, Lim S, Piao S, Song J, Kim J, Yang C. Statin upregulates the expression of klotho, an anti-aging gene, in experimental cyclosporine nephropathy. Nephron Exp Nephrol. 2012;120:e123-33 pubmed publisher
Desmoulin S, Wang L, Polin L, White K, Kushner J, Stout M, et al. Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter. Mol Pharmacol. 2012;82:591-600 pubmed
Garg A, Krysko D, Verfaillie T, Kaczmarek A, Ferreira G, Marysael T, et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J. 2012;31:1062-79 pubmed publisher
Thimiri Govinda Raj D, Ghesquière B, Tharkeshwar A, Coen K, Derua R, Vanderschaeghe D, et al. A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes. Mol Syst Biol. 2011;7:541 pubmed publisher
Nonomura K, Arai Y, Mitani H, Abe Dohmae S, Yokoyama S. Insulin down-regulates specific activity of ATP-binding cassette transporter A1 for high density lipoprotein biogenesis through its specific phosphorylation. Atherosclerosis. 2011;216:334-41 pubmed publisher
Mushtaq M, Nam T, Kim U. Critical role for CD38-mediated Ca2+ signaling in thrombin-induced procoagulant activity of mouse platelets and hemostasis. J Biol Chem. 2011;286:12952-8 pubmed publisher
Krämer Albers E, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, et al. Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?. Proteomics Clin Appl. 2007;1:1446-61 pubmed publisher
Lewandowski N, Ju S, Verbitsky M, Ross B, Geddie M, Rockenstein E, et al. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proc Natl Acad Sci U S A. 2010;107:16970-5 pubmed publisher
Tanaka N, Abe Dohmae S, Iwamoto N, Fitzgerald M, Yokoyama S. Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7. J Lipid Res. 2010;51:2591-9 pubmed publisher
Zhang Y, Liu R, Ni M, Gill P, Lee A. Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. J Biol Chem. 2010;285:15065-75 pubmed publisher
Feldmann A, Winterstein C, White R, Trotter J, Krämer Albers E. Comprehensive analysis of expression, subcellular localization, and cognate pairing of SNARE proteins in oligodendrocytes. J Neurosci Res. 2009;87:1760-72 pubmed publisher
Nirmalan N, Harnden P, Selby P, Banks R. Development and validation of a novel protein extraction methodology for quantitation of protein expression in formalin-fixed paraffin-embedded tissues using western blotting. J Pathol. 2009;217:497-506 pubmed publisher
Peyrottes I, Navarro V, Ondo Mendez A, Marcellin D, Bellanger L, Marsault R, et al. Immunoanalysis indicates that the sodium iodide symporter is not overexpressed in intracellular compartments in thyroid and breast cancers. Eur J Endocrinol. 2009;160:215-25 pubmed publisher
Johansson P, Dziegielewska K, Saunders N. Low levels of Na, K-ATPase and carbonic anhydrase II during choroid plexus development suggest limited involvement in early CSF secretion. Neurosci Lett. 2008;442:77-80 pubmed publisher
Dayem M, Basquin C, Navarro V, Carrier P, Marsault R, Chang P, et al. Comparison of expressed human and mouse sodium/iodide symporters reveals differences in transport properties and subcellular localization. J Endocrinol. 2008;197:95-109 pubmed publisher
Burgess B, Parkinson P, Racke M, Hirsch Reinshagen V, Fan J, Wong C, et al. ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. J Lipid Res. 2008;49:1254-67 pubmed publisher
Winterstein C, Trotter J, Krämer Albers E. Distinct endocytic recycling of myelin proteins promotes oligodendroglial membrane remodeling. J Cell Sci. 2008;121:834-42 pubmed publisher
Kadereit B, Kumar P, Wang W, Miranda D, Snapp E, Severina N, et al. Evolutionarily conserved gene family important for fat storage. Proc Natl Acad Sci U S A. 2008;105:94-9 pubmed
Padilla B, Cottrell G, Roosterman D, Pikios S, Muller L, Steinhoff M, et al. Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins. J Cell Biol. 2007;179:981-97 pubmed
Jahn T, Leifheit E, Gooch S, Sindhu S, Weinberg K. Lipid rafts are required for Kit survival and proliferation signals. Blood. 2007;110:1739-47 pubmed
Qu S, Perdomo G, Su D, D Souza F, Shachter N, Dong H. Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice. J Lipid Res. 2007;48:1476-87 pubmed
Roach W, Plomann M. PACSIN3 overexpression increases adipocyte glucose transport through GLUT1. Biochem Biophys Res Commun. 2007;355:745-50 pubmed
Tansley G, Burgess B, Bryan M, Su Y, Hirsch Reinshagen V, Pearce J, et al. The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. J Lipid Res. 2007;48:1022-34 pubmed
Pessach I, Shmelzer Z, Leto T, Dinauer M, Levy R. The C-terminal flavin domain of gp91phox bound to plasma membranes of granulocyte-like X-CGD PLB-985 cells is sufficient to anchor cytosolic oxidase components and support NADPH oxidase-associated diaphorase activity independent of cytosolic phosphol. J Leukoc Biol. 2006;80:630-9 pubmed
Tarn C, Skorobogatko Y, Taguchi T, Eisenberg B, von Mehren M, Godwin A. Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. Cancer Res. 2006;66:5477-86 pubmed
Chen P, Guzman J, Leong P, Yang L, Perianayagam A, Babilonia E, et al. Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concentration. Am J Physiol Cell Physiol. 2006;290:C1355-63 pubmed
Leong P, Devillez A, Sandberg M, Yang L, Yip D, Klein J, et al. Effects of ACE inhibition on proximal tubule sodium transport. Am J Physiol Renal Physiol. 2006;290:F854-63 pubmed
Cross W, Eardley I, Leese H, Southgate J. A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function. Am J Physiol Renal Physiol. 2005;289:F459-68 pubmed
Pohl J, Ring A, Korkmaz U, Ehehalt R, Stremmel W. FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts. Mol Biol Cell. 2005;16:24-31 pubmed
Holzer A, Katano K, Klomp L, Howell S. Cisplatin rapidly down-regulates its own influx transporter hCTR1 in cultured human ovarian carcinoma cells. Clin Cancer Res. 2004;10:6744-9 pubmed
Knox C, Belous A, Pierce J, Wakata A, Nicoud I, Anderson C, et al. Novel role of phospholipase C-delta1: regulation of liver mitochondrial Ca2+ uptake. Am J Physiol Gastrointest Liver Physiol. 2004;287:G533-40 pubmed
Xavier S, Piek E, Fujii M, Javelaud D, Mauviel A, Flanders K, et al. Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. J Biol Chem. 2004;279:15167-76 pubmed
Yang L, Zhong H, Leong P, Perianayagam A, Campese V, McDonough A. Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance. Am J Physiol Renal Physiol. 2003;284:F1056-65 pubmed
Magyar C, Zhang Y, Holstein Rathlou N, McDonough A. Proximal tubule Na transporter responses are the same during acute and chronic hypertension. Am J Physiol Renal Physiol. 2000;279:F358-69 pubmed
Zhang Y, Norian J, Magyar C, Holstein Rathlou N, Mircheff A, McDonough A. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition. Am J Physiol. 1999;276:F711-9 pubmed publisher
Zhang Y, Magyar C, Norian J, Holstein Rathlou N, Mircheff A, McDonough A. Reversible effects of acute hypertension on proximal tubule sodium transporters. Am J Physiol. 1998;274:C1090-100 pubmed publisher
product information
master code :
NB300-146
SKU :
NB300-146
product name :
Sodium Potassium ATPase Alpha 1 Antibody (464.6) - BSA Free
unit size :
0.05 ml (also 0.025 ml)
description :
The Sodium Potassium ATPase Alpha 1 Antibody (464.6) - BSA Free from Novus is a mouse monoclonal antibody to Sodium Potassium ATPase Alpha 1. This antibody reacts with bovine,canine,drosophila,guinea pig,human,insect - drosophila,mouse,ovine,porcine,primate,rabbit,rat,sheep,xenopus,yeast,frog - xenopus (african clawed frog). The Sodium Potassium ATPase Alpha 1 Antibody (464.6) - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunoblotting,Flow Cytometry,Immunohistochemistry-Paraffin.
target :
Sodium Potassium ATPase Alpha 1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
464.6
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Purified Sodium Potassium ATPase Alpha 1 from rabbit renal outer medulla. [UniProt# Q9N0Z6]
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Bovine,Canine,Drosophila,Guinea Pig,Human,Insect - Drosophila,Mouse,Ovine,Porcine,Primate,Rabbit,Rat,Sheep,Xenopus,Yeast,Frog - Xenopus (African Clawed Frog)
specificity :
This is specific for Na,K-ATPase alpha 1 subunit
theoretical molecular weight :
112 kDa
gene symbol :
ATP1A1
accessionNumbers :
P05023
applications :
Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunoblotting,Flow Cytometry,Immunohistochemistry-Paraffin
USD :
409 USD
alt names :
ATPase, Na+/K+ transporting, alpha 1 polypeptide, EC 3.6.3, EC 3.6.3.9, K-ATPase alpha-1 subunit, K-ATPase catalytic subunit alpha-A protein, MGC3285, MGC51750, Na, Na(+)/K(+) ATPase alpha-1 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na+, K+ ATPase alpha subunit, Na+/K+ ATPase 1, sodium pump 1, Sodium pump subunit alpha-1, sodium/potassium-transporting ATPase subunit alpha-1, sodium-potassium-ATPase, alpha 1 polypeptide
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.