alpha-Internexin Antibody (2E3) - BSA Free | Novus Biologicals NB300-140-0.1ml product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

alpha-Internexin Antibody (2E3) - BSA Free

catalog :

NB300-140-0.1ml

quantity :

0.1 ml (also 0.025 ml)

price :

549 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2.00E+03

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 34

Reference
Johnson A, McCurdy V, Gray Edwards H, Maguire A, Cochran J, Gross A, et al. Life-Limiting Peripheral Organ Dysfunction in Feline Sandhoff Disease Emerges after Effective CNS Gene Therapy. Ann Neurol. 2023;94:969-986 pubmed publisher
Forest F, Masliah Planchon J, Berger C, Prieur F, Girard E, Burel Vandenbos F, et al. High-grade childhood intra-parenchymal brain tumor clustering with ATRT and expanding the cancer spectrum related to inherited SMARCE1 truncating variations. Acta Neuropathol Commun. 2022;10:24 pubmed publisher
Bielle F, Di Stefano A, Meyronet D, Picca A, Villa C, Bernier M, et al. Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features. Brain Pathol. 2017;: pubmed publisher
Breton Q, Plouhinec H, Prunier Mirebeau D, Boisselier B, Michalak S, Menei P, et al. BRAF-V600E immunohistochemistry in a large series of glial and glial-neuronal tumors. Brain Behav. 2017;7:e00641 pubmed publisher
Bielle F, Ducray F, Mokhtari K, Dehais C, Adle Biassette H, Carpentier C, et al. Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas. Brain Pathol. 2017;27:567-579 pubmed publisher
Matsumura N, Nobusawa S, Ikota H, Hirato J, Hirose T, Yokoo H, et al. Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors. Brain Tumor Pathol. 2015;32:261-7 pubmed publisher
Nagaishi M, Yokoo H, Nobusawa S, Fujii Y, Sugiura Y, Suzuki R, et al. Localized overexpression of alpha-internexin within nodules in multinodular and vacuolating neuronal tumors. Neuropathology. 2015;35:561-8 pubmed publisher
Figarella Branger D, Mokhtari K, Dehais C, Jouvet A, Uro Coste E, Colin C, et al. Mitotic index, microvascular proliferation, and necrosis define 3 groups of 1p/19q codeleted anaplastic oligodendrogliomas associated with different genomic alterations. Neuro Oncol. 2014;16:1244-54 pubmed publisher
Reyes Botero G, Giry M, Mokhtari K, Labussiere M, Idbaih A, Delattre J, et al. Molecular analysis of diffuse intrinsic brainstem gliomas in adults. J Neurooncol. 2014;116:405-11 pubmed publisher
Nagaishi M, Suzuki A, Nobusawa S, Yokoo H, Nakazato Y. Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion. Brain Tumor Pathol. 2014;31:257-64 pubmed publisher
Takano S, Kato Y, Yamamoto T, Kaneko M, Ishikawa E, Tsujimoto Y, et al. Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J Neurooncol. 2012;108:361-73 pubmed publisher
Seilhean D, Le Ber I, Sarazin M, Lacomblez L, Millecamps S, Salachas F, et al. Fronto-temporal lobar degeneration: neuropathology in 60 cases. J Neural Transm (Vienna). 2011;118:753-64 pubmed publisher
Mokhtari K, Ducray F, Kros J, Gorlia T, Idbaih A, Taphoorn M, et al. Alpha-internexin expression predicts outcome in anaplastic oligodendroglial tumors and may positively impact the efficacy of chemotherapy: European organization for research and treatment of cancer trial 26951. Cancer. 2011;117:3014-26 pubmed publisher
San Millan B, Kaci R, Polivka M, Robert G, Heran F, Gueguen A, et al. [Gliomatosis cerebri: a biopsy and autopsy case report]. Ann Pathol. 2010;30:25-9 pubmed publisher
Wang P, Wang S, Hsieh C, Chien C. Neural expression of alpha-internexin promoter in vitro and in vivo. J Cell Biochem. 2006;97:275-87 pubmed
Ko T, Chien C, Lu K. The expression of alpha-internexin and peripherin in the developing mouse pineal gland. J Biomed Sci. 2005;12:777-89 pubmed
Rauch U, Klotz M, Maas Omlor S, Wink E, Hänsgen A, Hagl C, et al. Expression of intermediate filament proteins and neuronal markers in the human fetal gut. J Histochem Cytochem. 2006;54:39-46 pubmed
Uchikado H, Shaw G, Wang D, Dickson D. Screening for neurofilament inclusion disease using alpha-internexin immunohistochemistry. Neurology. 2005;64:1658-9 pubmed
Chien C, Liu T, Ho C, Lu K. Overexpression of neuronal intermediate filament protein alpha-internexin in PC12 cells. J Neurosci Res. 2005;80:693-706 pubmed
Jing Ping Z, Tian Q, Sakagami H, Kondo H, Endo S, Suzuki T. p55 protein is a member of PSD scaffold proteins in the rat brain and interacts with various PSD proteins. Brain Res Mol Brain Res. 2005;135:204-16 pubmed
Josephs K, Uchikado H, McComb R, Bashir R, Wszolek Z, Swanson J, et al. Extending the clinicopathological spectrum of neurofilament inclusion disease. Acta Neuropathol. 2005;109:427-32 pubmed
Cairns N, Grossman M, Arnold S, Burn D, Jaros E, Perry R, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 2004;63:1376-84 pubmed
Rajasalu T, Teesalu K, Janmey P, Uibo R. Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals. Immunol Lett. 2004;94:153-60 pubmed
Cairns N, Uryu K, Bigio E, Mackenzie I, Gearing M, Duyckaerts C, et al. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathol. 2004;108:213-23 pubmed
Cairns N, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie I, et al. alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. Am J Pathol. 2004;164:2153-61 pubmed
Yuan A, Rao M, Kumar A, Julien J, Nixon R. Neurofilament transport in vivo minimally requires hetero-oligomer formation. J Neurosci. 2003;23:9452-8 pubmed
Ortino B, Inverardi F, Morante Oria J, Fairen A, Frassoni C. Substrates and routes of migration of early generated neurons in the developing rat thalamus. Eur J Neurosci. 2003;18:323-32 pubmed
Donner L, Teshima I. Peripheral medulloepithelioma: an immunohistochemical, ultrastructural, and cytogenetic study of a rare, chemotherapy-sensitive, pediatric tumor. Am J Surg Pathol. 2003;27:1008-12 pubmed
Stachowiak E, Fang X, Myers J, Dunham S, Stachowiak M. cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1). J Neurochem. 2003;84:1296-312 pubmed
Talbot N, Powell A, Garrett W. Spontaneous differentiation of porcine and bovine embryonic stem cells (epiblast) into astrocytes or neurons. In Vitro Cell Dev Biol Anim. 2002;38:191-7 pubmed
McGraw T, Mickle J, Shaw G, Streit W. Axonally transported peripheral signals regulate alpha-internexin expression in regenerating motoneurons. J Neurosci. 2002;22:4955-63 pubmed
Larivière R, Nguyen M, Ribeiro da Silva A, Julien J. Reduced number of unmyelinated sensory axons in peripherin null mice. J Neurochem. 2002;81:525-32 pubmed
Shaw G, Morse S, Ararat M, Graham F. Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 2002;16:869-71 pubmed
Evans J, Sumners C, Moore J, Huentelman M, Deng J, Gelband C, et al. Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem. J Neurophysiol. 2002;87:1076-85 pubmed

product information

master code :

NB300-140

SKU :

NB300-140-0.1ml

product name :

alpha-Internexin Antibody (2E3) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The alpha-Internexin Antibody (2E3) - BSA Free from Novus is a mouse monoclonal antibody to alpha-Internexin. This antibody reacts with bovine,human,mouse,porcine,rat. The alpha-Internexin Antibody (2E3) - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.

target :

alpha-Internexin

category :

Primary Antibodies

buffer :

50% PBS, 50% Glycerol

clonality :

Monoclonal

clone :

2.00E+03

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Purified recombinant rat alpha Internexin expressed in and purified from E. coli [UniProt# P23565]

isotype :

IgG1

purity :

Affinity purified

species :

Bovine,Human,Mouse,Porcine,Rat

theoretical molecular weight :

66 kDa

gene symbol :

INA

accessionNumbers :

P23565

applications :

IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western

USD :

549 USD

alt names :

66 kDa neurofilament protein, alpha-Inx, FLJ18662, FLJ57501, internexin neuronal intermediate filament protein, alpha, MGC12702, NEF5, Neurofilament 5, neurofilament 5 (66kD), Neurofilament-66, neurofilament-66, tax-binding protein, NF-66alpha-internexin, TXBP-1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage