product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
alpha-Internexin Antibody
catalog :
NB300-139
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
17B4
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - free floating section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig s3b
Atkinson R, LEUNG J, Bender J, Kirkcaldie M, Vickers J, King A. TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy. Dis Model Mech. 2021;: pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 3
Laramée M, Smolders K, Hu T, Bronchti G, Boire D, Arckens L. Congenital Anophthalmia and Binocular Neonatal Enucleation Differently Affect the Proteome of Primary and Secondary Visual Cortices in Mice. PLoS ONE. 2016;11:e0159320 pubmed publisher
Huynh D, Hu J, Schneider J, Tsolova K, Soderblom E, Watson A, et al. O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations. bioRxiv. 2023;: pubmed publisher
Harper J, Gordon S, Chan C, Wang H, Lindemuth E, Galardi C, et al. CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption. Nat Med. 2020;26:519-528 pubmed publisher
Péricart S, Tosolini M, Gravelle P, Rossi C, Traverse Glehen A, Amara N, et al. Profiling Immune Escape in Hodgkin's and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining. Cancers (Basel). 2018;10: pubmed publisher
Wang J, Ti Y, Wang Y, Guo G, Jiang H, Chang M, et al. LAG-3 Represents a Marker of CD4+ T Cells with Regulatory Activity in Patients with Bone Fracture. Immunol Invest. 2018;47:492-503 pubmed publisher
Sabins N, Chornoguz O, Leander K, Kaplan F, Carter R, Kinder M, et al. TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1. J Immunol. 2017;199:4091-4102 pubmed publisher
Ma Q, Huang D, Zhang H, Wang S, Chen X. Function and regulation of LAG3 on CD4+CD25- T cells in non-small cell lung cancer. Exp Cell Res. 2017;360:358-364 pubmed publisher
Casati C, Camisaschi C, Novellino L, Mazzocchi A, Triebel F, Rivoltini L, et al. Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation. J Immunol. 2008;180:3782-8 pubmed
Triebel F, Hacene K, Pichon M. A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors. Cancer Lett. 2006;235:147-53 pubmed
Macon Lemaitre L, Triebel F. The negative regulatory function of the lymphocyte-activation gene-3 co-receptor (CD223) on human T cells. Immunology. 2005;115:170-8 pubmed
Di Carlo E, Cappello P, Sorrentino C, D Antuono T, Pellicciotta A, Giovarelli M, et al. Immunological mechanisms elicited at the tumour site by lymphocyte activation gene-3 (LAG-3) versus IL-12: sharing a common Th1 anti-tumour immune pathway. J Pathol. 2005;205:82-91 pubmed
Demeure C, Wolfers J, Martin Garcia N, Gaulard P, Triebel F. T Lymphocytes infiltrating various tumour types express the MHC class II ligand lymphocyte activation gene-3 (LAG-3): role of LAG-3/MHC class II interactions in cell-cell contacts. Eur J Cancer. 2001;37:1709-18 pubmed
product information
master code :
NB300-139
SKU :
NB300-139
product name :
alpha-Internexin Antibody
unit size :
0.1 ml (also 0.025 ml)
description :
The alpha-Internexin Antibody from Novus is a rabbit polyclonal antibody to alpha-Internexin. This antibody reacts with bovine,equine,human,mouse,porcine,rat. The alpha-Internexin Antibody has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
alpha-Internexin
category :
Primary Antibodies
buffer :
Supplied as serum
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Purified recombinant rat alpha internexin expressed in and purified from E. coli. [UniProt# P23565]
isotype :
IgG
purity :
Unpurified
species :
Bovine,Equine,Human,Mouse,Porcine,Rat
theoretical molecular weight :
66 kDa
gene symbol :
INA
accessionNumbers :
P23565
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
409 USD
alt names :
66 kDa neurofilament protein, alpha-Inx, FLJ18662, FLJ57501, internexin neuronal intermediate filament protein, alpha, MGC12702, NEF5, Neurofilament 5, neurofilament 5 (66kD), Neurofilament-66, neurofilament-66, tax-binding protein, NF-66alpha-internexin, TXBP-1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.