product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Ubiquitin Antibody
catalog :
NB300-129
quantity :
0.05 ml
price :
499 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
more info or order :
Novus Biologicals product webpage
citations: 14
Reference
Wen J, Li Y, Qin Y, Yan L, Zhang K, Li A, et al. Lycorine protects motor neurons against TDP-43 proteinopathy-induced degeneration in cross-species models with amyotrophic lateral sclerosis. Pharmacol Res. 2024;210:107518 pubmed publisher
Sachs W, Blume L, Loreth D, Schebsdat L, Hatje F, Koehler S, et al. The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration. Nat Commun. 2024;15:1897 pubmed publisher
Sung W, Noh M, Nahm M, Kim Y, Ki C, Kim Y, et al. Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia. J Neuroinflammation. 2024;21:47 pubmed publisher
Yang S, Yang G, Wang X, Xiang J, Kang L, Liang Z. SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells. Cell Death Dis. 2023;14:646 pubmed publisher
Reichelt J, Sachs W, Fr xf6 mbling S, Fehlert J, Studencka Turski M, Betz A, et al. Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis. Nat Commun. 2023;14:2114 pubmed publisher
Panicker N, Kam T, Wang H, Neifert S, Chou S, Kumar M, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. 2022;: pubmed publisher
Garcia L, Tenev T, Newman R, Haich R, Liccardi G, John S, et al. Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance. Nat Commun. 2021;12:3364 pubmed publisher
El Manaa W, Duplan E, Goiran T, Lauritzen I, Vaillant Beuchot L, Lacas Gervais S, et al. Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology. Autophagy. 2021;:1-23 pubmed publisher
Lin L, Kost E, Lin C, Valente P, Wang C, Kolonin M, et al. PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer. Cell Rep. 2020;33:108253 pubmed publisher
Sachs W, Sachs M, Krüger E, Zielinski S, Kretz O, Huber T, et al. Distinct Modes of Balancing Glomerular Cell Proteostasis in Mucolipidosis Type II and III Prevent Proteinuria. J Am Soc Nephrol. 2020;31:1796-1814 pubmed publisher
Yang P, Dong X, Zhang Y. MicroRNA profiles in plasma samples from young metabolically healthy obese patients and miRNA-21 are associated with diastolic dysfunction via TGF-β1/Smad pathway. J Clin Lab Anal. 2020;34:e23246 pubmed publisher
Tang Y, Reissig S, Glasmacher E, Regen T, Wanke F, Nikolaev A, et al. Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis. Gastroenterology. 2019;156:692-707.e7 pubmed publisher
Llombart V, Trejo S, Bronsoms S, Morancho A, Feifei M, Faura J, et al. Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry. J Proteomics. 2017;152:243-253 pubmed publisher
Muñoz Sáez E, de Munck García E, Arahuetes Portero R, Martínez A, Solas Alados M, Miguel B. Analysis of β-N-methylamino-L-alanine (L-BMAA) neurotoxicity in rat cerebellum. Neurotoxicology. 2015;48:192-205 pubmed publisher
product information
master code :
NB300-129
SKU :
NB300-129
product name :
Ubiquitin Antibody
unit size :
0.05 ml
description :
The Ubiquitin Antibody from Novus is a rabbit polyclonal antibody to Ubiquitin. This antibody reacts with human,mouse,rat. The Ubiquitin Antibody has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
Ubiquitin
category :
Primary Antibodies
buffer :
Supplied as serum
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Purified ubiquitin conjugated with glutaraldehyde to KLH
isotype :
IgG
purity :
Unpurified
species :
Human,Mouse,Rat
specificity :
This antibody recognizes ubiquitinated inclusion bodies and both the mono- and polyubiquitin forms
theoretical molecular weight :
8.5 kDa
gene symbol :
RPS27A
applications :
IF/IHC,Western Blot,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
499 USD
alt names :
RPS27A, UBA52, UBB ubiquitin B, UBC
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.