product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal NK1R Antibody
catalog :
NB300-119B
quantity :
0.1 ml
price :
299.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human, mouse, rat
application :
immunohistochemistry, flow cytometry
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB300-119B
Product Name :
Rabbit Polyclonal NK1R Antibody
List Price :
299.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
NK-1R, NK1Rneurokinin 1 receptor, NKIR, SPRsubstance-P receptor, TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor), tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor), tachykinin receptor 1NK-1 receptor
Background :
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).
Buffer :
PBS
Clonality :
Polyclonal
Conjugate :
Biotin
Application Summary :
Flow Cytometry, Immunohistochemistry
Host :
Rabbit
Immunogen :
A peptide derived from the N-terminus region between amino acids 1-50 of human Neurokinin 1 Receptor [UniProt# P25103]
Localization :
Cell Membrane
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Reacts with human, mouse and rat. Immunogen has 94% sequence identity with guinea pig. Mouse reactivity is from a customer review.
Storage :
Store at 4C in the dark.
Swissprot Human :
P25103
TMW :
46 kDa
Uses :
This Neurokinin 1 Receptor Antibody is useful for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry and Western blot.
Research Area :
GPCR, Neuronal Cell Markers, Neuroscience, Neurotransmission
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.