product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NK1R Antibody - BSA Free
catalog :
NB300-119
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
H3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 1a
Henssen A, Odersky A, Szymansky A, Seiler M, Althoff K, Beckers A, et al. Targeting tachykinin receptors in neuroblastoma. Oncotarget. 2017;8:430-443 pubmed publisher
Zheng Y, Sang M, Liu F, Gu L, Li J, Wu Y, et al. Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor. Oncol Rep. 2023;50: pubmed publisher
Restaino A, Walz A, Vermeer S, Barr J, Kov xe1 cs A, Fettig R, et al. Functional neuronal circuits promote disease progression in cancer. Sci Adv. 2023;9:eade4443 pubmed publisher
Ogawa K, Khan K, Koshiba A, Fujishita A, Horiguchi G, Teramukai S, et al. Association between tissue stress reaction and ACE2/TMPRSS2 expression in endometria of reproductive aged women before and during Covid-19 pandemic. BMC Womens Health. 2023;23:229 pubmed publisher
Zhu E, Liu Y, Zhong M, Liu Y, Jiang X, Shu X, et al. Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease. Front Immunol. 2023;14:1142240 pubmed publisher
Brzozowska M, Romaniewicz M, Ca x142 ka J, Jana B. Effects of Substance P and Neurokinin A on the Contractile Activity of Inflamed Porcine Uterus. Int J Mol Sci. 2022;23: pubmed publisher
Rodriguez E, Pei G, Kim S, German A, Robinson P. Substance P Antagonism as a Novel Therapeutic Option to Enhance Efficacy of Cisplatin in Triple Negative Breast Cancer and Protect PC12 Cells against Cisplatin-Induced Oxidative Stress and Apoptosis. Cancers (Basel). 2021;13: pubmed publisher
Guan M, Ying S, Wang Y. Increased expression of transient receptor potential channels and neurogenic factors associates with cough severity in a guinea pig model. BMC Pulm Med. 2021;21:187 pubmed publisher
Xu X, Cai X, Liu X, Guo S. Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis. Reprod Biol Endocrinol. 2021;19:25 pubmed publisher
Morelli A, Sumpter T, Rojas Canales D, Bandyopadhyay M, Chen Z, Tkacheva O, et al. Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells. Cell Rep. 2020;30:3448-3465.e8 pubmed publisher
Talbot S, Doyle B, Huang J, Wang J, Ahmadi M, Roberson D, et al. Vagal sensory neurons drive mucous cell metaplasia. J Allergy Clin Immunol. 2020;145:1693-1696.e4 pubmed publisher
Zhou Y, Wang M, Tong Y, Liu X, Zhang L, Dong D, et al. miR-206 Promotes Cancer Progression by Targeting Full-Length Neurokinin-1 Receptor in Breast Cancer. Technol Cancer Res Treat. 2019;18:1533033819875168 pubmed publisher
Li Q, Wu X, Yang Y, Zhang Y, He F, Xu X, et al. Tachykinin NK1 receptor antagonist L-733,060 and substance P deletion exert neuroprotection through inhibiting oxidative stress and cell death after traumatic brain injury in mice. Int J Biochem Cell Biol. 2019;107:154-165 pubmed publisher
Bubak A, Como C, Blackmon A, Frietze S, Mescher T, Jones D, et al. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes. J Infect Dis. 2018;218:1324-1335 pubmed publisher
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018;98:90-108.e5 pubmed publisher
Zhang Z, Zheng W, Xie H, Chai R, Wang J, Zhang H, et al. Up-regulated expression of substance P in CD8+ T cells and NK1R on monocytes of atopic dermatitis. J Transl Med. 2017;15:93 pubmed publisher
product information
master code :
NB300-119
SKU :
NB300-119
product name :
NK1R Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The NK1R Antibody - BSA Free from Novus is a rabbit polyclonal antibody to NK1R. This antibody reacts with human,mouse,porcine,rat. The NK1R Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Flow Cytometry,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.
target :
NK1R
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A peptide derived from the N-terminus region between amino acids 1-50 of human Neurokinin 1 Receptor. [UniProt# P25103]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Rat
theoretical molecular weight :
46 kDa
gene symbol :
TACR1
applications :
Immunohistochemistry,Flow Cytometry,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
NK-1R, NK1Rneurokinin 1 receptor, NKIR, SPRsubstance-P receptor, TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor), tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor), tachykinin receptor 1NK-1 receptor
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.