NMDAR1 Antibody (R1JHL) | Novus Biologicals NB300-118 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NMDAR1 Antibody (R1JHL)

catalog :

NB300-118

quantity :

0.015 mg

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

R1JHL

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 7a	Puntambekar S, Moutinho M, Lin P, Jadhav V, Tumbleson Brink D, Balaji A, et al. CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease. Mol Neurodegener. 2022;17:47 pubmed publisher
	Hossen E, Funahashi Y, Faruk M, Ahammad R, Amano M, Yamada K, et al. Rho-Kinase/ROCK Phosphorylates PSD-93 Downstream of NMDARs to Orchestrate Synaptic Plasticity. Int J Mol Sci. 2022;24: pubmed publisher
	Perri R, Mantello A, Rosa D, Beleboni R. Silencing of the GluN1-NMDA Glutamate Receptor Subunit by Intranasal siRNA Increases the Latency Time for Seizures in the Pilocarpine Rodent Model of Epilepsy. Pharmaceuticals (Basel). 2022;15: pubmed publisher
	Yamahashi Y, Lin Y, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, et al. Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning. Mol Psychiatry. 2022;27:3479-3492 pubmed publisher
	Lin Y, Yamahashi Y, Kuroda K, Faruk M, Zhang X, Yamada K, et al. Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway. Neurochem Int. 2021;143:104935 pubmed publisher
	Al Rahim M, Yoon Y, Dimovasili C, Shao Z, Huang Q, Zhang E, et al. Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-aspartate receptor. Brain Commun. 2020;2:fcaa100 pubmed publisher
	Wang Y, Kerrisk Campbell M, Tom I, Foreman O, Hanson J, Sheng M. PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function. Sci Rep. 2020;10:10951 pubmed publisher
	Nitta S, Kusakari Y, Yamada Y, Kubo T, Neo S, Igarashi H, et al. Conversion of mesenchymal stem cells into a canine hepatocyte-like cells by Foxa1 and Hnf4a. Regen Ther. 2020;14:165-176 pubmed publisher
	Amin S, Anderson K, Boudreau C, Martinez Ledesma E, Kocakavuk E, Johnson K, et al. Comparative Molecular Life History of Spontaneous Canine and Human Gliomas. Cancer Cell. 2020;37:243-257.e7 pubmed publisher
	Carcolé M, Kummer S, Gonçalves L, Zamanillo D, Merlos M, Dickenson A, et al. Sigma-1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain. Br J Pharmacol. 2019;176:3939-3955 pubmed publisher
	Shi Y, Hung S, Rocha G, Lin S, Linares G, Staats K, et al. Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons. JCI Insight. 2019;5: pubmed publisher
	Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al. Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Dis Model Mech. 2019;12: pubmed publisher
	Shi Y, Lin S, Staats K, Li Y, Chang W, Hung S, et al. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nat Med. 2018;24:313-325 pubmed publisher
	Bertolo A, Pavlicek D, Gemperli A, Baur M, Pötzel T, Stoyanov J. Increased motility of mesenchymal stem cells is correlated with inhibition of stimulated peripheral blood mononuclear cells in vitro. J Stem Cells Regen Med. 2017;13:62-74 pubmed
	Waksman R, Lipinski M, Acampado E, Cheng Q, Adams L, Torii S, et al. Comparison of Acute Thrombogenicity for Metallic and Polymeric Bioabsorbable Scaffolds: Magmaris Versus Absorb in a Porcine Arteriovenous Shunt Model. Circ Cardiovasc Interv. 2017;10: pubmed publisher
	Gorska Ponikowska M, Perricone U, Kuban Jankowska A, Lo Bosco G, Barone G. 2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor. J Cell Physiol. 2017;232:3030-3049 pubmed publisher
	Bertolo A, Capossela S, Fränkl G, Baur M, Pötzel T, Stoyanov J. Oxidative status predicts quality in human mesenchymal stem cells. Stem Cell Res Ther. 2017;8:3 pubmed publisher
	Hewett S, Shi J, Gong Y, Dhandapani K, Pilbeam C, Hewett J. Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 (STIMULATORY PROTEIN-1). J Biol Chem. 2016;291:27279-27288 pubmed publisher
	He Z, Riva M, Björk P, Swärd K, Morgelin M, Leanderson T, et al. CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes. PLoS ONE. 2016;11:e0156377 pubmed publisher
	Brai E, Marathe S, Astori S, Fredj N, Perry E, Lamy C, et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015;9:447 pubmed publisher
	Bertolo A, Gemperli A, Gruber M, Gantenbein B, Baur M, PÃ¶tzel T, et al. In vitro cell motility as a potential mesenchymal stem cell marker for multipotency. Stem Cells Transl Med. 2015;4:84-90 pubmed publisher
	Bertolo A, Steffen F, Malonzo Marty C, Stoyanov J. Canine Mesenchymal Stem Cell Potential and the Importance of Dog Breed: Implication for Cell-Based Therapies. Cell Transplant. 2015;24:1969-80 pubmed publisher
	Plaza Zabala A, Li X, Milovanovic M, Loweth J, Maldonado R, Berrendero F, et al. An investigation of interactions between hypocretin/orexin signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions and after cocaine exposure. Neurosci Lett. 2013;557 Pt B:101-6 pubmed publisher
	Tao P, Chen C, Huang E. Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring. J Biomed Sci. 2011;18:64 pubmed publisher
	Ferrario C, Loweth J, Milovanovic M, Wang X, Wolf M. Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens. Neurosci Lett. 2011;490:180-4 pubmed publisher
	Mashkina A, Cizkova D, Vanicky I, Boldyrev A. NMDA receptors are expressed in lymphocytes activated both in vitro and in vivo. Cell Mol Neurobiol. 2010;30:901-7 pubmed publisher
	Garraway S, Xu Q, Inturrisi C. siRNA-mediated knockdown of the NR1 subunit gene of the NMDA receptor attenuates formalin-induced pain behaviors in adult rats. J Pain. 2009;10:380-90 pubmed publisher
	Lim G, Wang S, Zeng Q, Sung B, Yang L, Mao J. Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor. J Neurosci. 2005;25:11145-54 pubmed
	Nagy J, Kolok S, Dezso P, Boros A, Szombathelyi Z. Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones. Neurochem Int. 2003;42:35-43 pubmed

product information

master code :

NB300-118

SKU :

NB300-118

product name :

NMDAR1 Antibody (R1JHL)

unit size :

0.015 mg

description :

The NMDAR1 Antibody (R1JHL) from Novus is a mouse monoclonal antibody to NMDAR1. This antibody reacts with human,mouse,rat. The NMDAR1 Antibody (R1JHL) has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.

target :

NMDAR1

category :

Primary Antibodies

clonality :

Monoclonal

clone :

R1JHL

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Fusion protein containing amino acids 1-564 of the NMDAR1 subunit. Accession # P35439

isotype :

IgG

purity :

Tissue culture supernatant

species :

Human,Mouse,Rat

specificity :

Specific for endogenous levels of the ~120 kDa NR1 subunit of the NMDA receptor

theoretical molecular weight :

120 kDa

gene symbol :

GRIN1

accessionNumbers :

P35439

applications :

Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation

USD :

469 USD

alt names :

glutamate [NMDA] receptor subunit zeta-1, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA1, NMDAR1glutamate [NMDA] receptor subunit zeta 1, NMD-R1, N-methyl-D-aspartate receptor channel, subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NR1

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage