product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Histone H4 [ac Lys5] Antibody - BSA Free
catalog :
NB21-2024
quantity :
0.05 mg (also 0.025 mg)
price :
329 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
2D8
reactivity :
human, mouse, rat, fruit fly
application :
western blot, immunocytochemistry, chromatin immunoprecipitation, dot blot
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; loading ...; fig 5f
Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv. 2021;7: pubmed publisher
  • western blot; fruit fly ; 1:1000; loading ...; fig 2a
Boltengagen M, Huang A, Boltengagen A, Trixl L, Lindner H, Kremser L, et al. A novel role for the histone acetyltransferase Hat1 in the CENP-A/CID assembly pathway in Drosophila melanogaster. Nucleic Acids Res. 2016;44:2145-59 pubmed publisher
Franco Garc xed a A, G xf3 mez Murcia V, Fern xe1 ndez G xf3 mez F, Gonz xe1 lez Andreu R, Hidalgo J, Victoria Milan xe9 s M, et al. Morphine-withdrawal aversive memories and their extinction modulate H4K5 acetylation and Brd4 activation in the rat hippocampus and basolateral amygdala. Biomed Pharmacother. 2023;165:115055 pubmed publisher
Rishi J, Timme K, White H, Kerns K, Keating A. Obesity partially potentiates dimethylbenz[a]anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice†. Biol Reprod. 2023;108:694-707 pubmed publisher
Akiyama M, Ozaki K, Kawano T, Yamada O, Kawauchi K, Ida H, et al. Telomerase activation as a repair response to radiation-induced DNA damage in Y79 retinoblastoma cells. Cancer Lett. 2013;340:82-7 pubmed publisher
Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, et al. EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. Cancer Sci. 2011;102:351-60 pubmed publisher
Fabricius E, Kruse Boitschenko U, Khoury R, Wildner G, Raguse J, Klein M, et al. Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues. Int J Oncol. 2009;35:1377-94 pubmed
Fabricius E, Kruse Boitschenko U, Khoury R, Wildner G, Raguse J, Klein M. Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues. Int J Oncol. 2009;34:1257-79 pubmed
Xiao Y, Gao X, Gannot G, Emmert Buck M, Srivastava S, Wagner P, et al. Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection. Int J Cancer. 2008;122:2178-86 pubmed publisher
Zhang J, Eguchi J, Kruse C, Gomez G, Fakhrai H, Schroter S, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-575 pubmed publisher
Deissler H, Deissler H, Lang G, Lang G. Generation and characterization of iBREC: novel hTERT-immortalized bovine retinal endothelial cells. Int J Mol Med. 2005;16:65-70 pubmed
Masutomi K, Possemato R, Wong J, Currier J, Tothova Z, Manola J, et al. The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A. 2005;102:8222-7 pubmed
Blasco M, Hahn W. Evolving views of telomerase and cancer. Trends Cell Biol. 2003;13:289-94 pubmed
product information
master code :
NB21-2024
SKU :
NB21-2024
product name :
Histone H4 [ac Lys5] Antibody - BSA Free
unit size :
0.05 mg (also 0.025 mg)
description :
The Histone H4 [ac Lys5] Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Histone H4. This antibody reacts with human,mammal,mouse,porcine,rat. The Histone H4 [ac Lys5] Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Dot Blot,Chromatin Immunoprecipitation (ChIP).
target :
Histone H4
category :
Primary Antibodies
buffer :
PBS, 30% Glycerol
clonality :
Polyclonal
concentration :
0.78 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic aceylated peptide surrounding Lysine 5 of human Histone H4 [Swiss Prot P62805].
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mammal,Mouse,Porcine,Rat
gene symbol :
H4C16
accessionNumbers :
P62805
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Dot Blot,Chromatin Immunoprecipitation (ChIP)
USD :
329 USD
alt names :
H4/A, H4/B, H4/C, H4/D, H4/E, H4/G, H4/H, H4/I, H4/J, H4/K, H4/M, H4/N, H4/O, H4/p, H4F2, H4FA, H4FB, H4FC, H4FD, H4FE, H4FG, H4FH, H4FI, H4FJ, H4FK, H4FM, H4FN, H4FO, H4K5ac, HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4, HIST2H4A, HIST2H4B, histone 4, H4, histone cluster 4, H4, histone H4, MGC24116
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.