product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal Histone H3 Antibody
catalog :
NB21-1254F
quantity :
0.05 mg
price :
209.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
human, mouse
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB21-1254F
Product Name :
Rabbit Polyclonal Histone H3 Antibody
List Price :
209.00 USD
Product Type :
Primary Antibodies
Package Size :
0.05 mg
AltNames :
H3 histone, family 3A, H3.3AH3F3H3F3B, H3.3B, histone H3.3, MGC87782, MGC87783
Background :
Histone H3 acetylation at lysine 36 results from the activity of GCN5, which regulates transcription. H3K36ac is usually found in the promoters of RNA polymerase II-transcribed genes. When acetylation of this lysine is replaced by methylation, the activation of transcription is eliminated. This switch-like activity seems to determine the chromatin function found in transcription units. Set2 associates with RNA polymerase II and histone H3 at lysine 36, and seems to be responsible for proper acetylation of coding regions. The co-activity of Set2 and Rpd3S is important for ensuring that transcription of intragenic sequences does not occur, and is related to the acetylation and methylation of histone H3 at lysine 36.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
FITC
Application Summary :
Western Blot, Dot Blot
Host :
Rabbit
Immunogen :
Synthetic acetylated peptide surrounding Lysine 36 of human Histone H3.2 [Swiss Prot Q71DI3].
Localization :
Nucleus. Chromosome
Marker :
Nuclear Marker
Modification :
ac Lys36
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology.
Storage :
Store at 4C in the dark.
Swissprot Human :
Q71DI3
Uses :
This H3K36ac antibody is useful in Dot Blot and Western Blot where a band is seen ~15 kDa.
Research Area :
Chromatin Modifiers, Chromatin Research, Epigenetics, Histones and Modified Histones
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.