Complement C4b/d Antibody (16D2) | Novus Biologicals NB200-541 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Complement C4b/d Antibody (16D2)

catalog :

NB200-541

quantity :

0.05 mg

price :

349 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

16D2

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Zhang H, Cavazzoni C, Podest xe0 M, Bechu E, Ralli G, Chandrakar P, et al. IL-21-producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts. JCI Insight. 2023;8: pubmed publisher
Xiao J, Li Y, Rowley T, Huang J, Yolken R, Viscidi R. Immunotherapy targeting the PD-1 pathway alleviates neuroinflammation caused by chronic Toxoplasma infection. Sci Rep. 2023;13:1288 pubmed publisher
Zhang H, Cavazzoni C, Hanson B, Bechu E, Podest xe0 M, Azzi J, et al. Transcriptionally Distinct B Cells Infiltrate Allografts After Kidney Transplantation. Transplantation. 2023;107:e47-e57 pubmed publisher
Gassen R, Borges T, P xe9 rez S xe1 ez M, Zhang H, Al Jurdi A, Llin xe0 s Mallol L, et al. T cell depletion increases humoral response by favoring T follicular helper cells expansion. Am J Transplant. 2022;22:1766-1778 pubmed publisher
Ahmadi A, Moghadasali R, Ezzatizadeh V, Taghizadeh Z, Nassiri S, Asghari Vostikolaee M, et al. Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates Proteinuria. Sci Rep. 2019;9:15467 pubmed publisher
Miyahara Y, Khattar M, Schroder P, Mierzejewska B, Deng R, Han R, et al. Anti-TCR? mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells. Am J Transplant. 2012;12:1409-18 pubmed publisher
Murata K, Fox Talbot K, Qian Z, Takahashi K, Stahl G, Baldwin W, et al. Synergistic deposition of C4d by complement-activating and non-activating antibodies in cardiac transplants. Am J Transplant. 2007;7:2605-14 pubmed
Zhang Y, Kirken R, Furian L, Janczewska S, Qu X, Hancock W, et al. Allograft rejection requires STAT5a/b-regulated antiapoptotic activity in T cells but not B cells. J Immunol. 2006;176:128-37 pubmed
Gadjeva M, Verschoor A, Brockman M, Jezak H, Shen L, Knipe D, et al. Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice. J Immunol. 2002;169:5489-95 pubmed
Paul E, Pozdnyakova O, Mitchell E, Carroll M. Anti-DNA autoreactivity in C4-deficient mice. Eur J Immunol. 2002;32:2672-9 pubmed

product information

master code :

NB200-541

SKU :

NB200-541

product name :

Complement C4b/d Antibody (16D2)

unit size :

0.05 mg

description :

The Complement C4b/d Antibody (16D2) from Novus is a rat monoclonal antibody to Complement C4b/d. This antibody reacts with mouse. The Complement C4b/d Antibody (16D2) has been validated for the following applications: Immunohistochemistry-Frozen,Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunoprecipitation,Immunoassay,Immunocytochemistry/ Immunofluorescence.

target :

Complement C4b/d

category :

Primary Antibodies

buffer :

0.2um filtered PBS and 0.1% BSA

clonality :

Monoclonal

clone :

16D2

concentration :

0.1 mg/ml

conjugate :

Unconjugated

host :

Rat

immunogen :

Cell-bound C4 of mouse origin.

isotype :

IgG2a

purity :

Protein G purified

species :

Mouse

specificity :

Antibody cross reacts with C4, C4b and C4d

gene symbol :

C4B

accessionNumbers :

P01029

applications :

Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Immunoprecipitation,Immunoassay,Immunocytochemistry/ Immunofluorescence

USD :

349 USD

alt names :

basic C4, Basic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, C4B1, C4B12, C4B2, C4B3, C4FMGC164979, CH, Chido form of C4, CO4C4B5, complement C4-B, complement C4B1a, complement component 4B, complement component 4B (Chido blood group), CPAMD3FLJ60561, EC 2.1.1.144, EC 2.7.11

storage :

Store at 4C.

more info or order :

Novus Biologicals product webpage