product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Complement C3 Antibody (11H9) - BSA Free
catalog :
NB200-540
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
11H9
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 2a
  • immunohistochemistry; mouse; loading ...; fig 3c
Liu T, Yang M, Xia Y, Jiang C, Li C, Jiang Z, et al. Microarray-based analysis of renal complement components reveals a therapeutic target for lupus nephritis. Arthritis Res Ther. 2021;23:223 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 1g
Griffin P, Sheehan P, Dimitry J, Guo C, Kanan M, Lee J, et al. REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis. elife. 2020;9: pubmed publisher
O Shea T, Ao Y, Wang S, Ren Y, Cheng A, Kawaguchi R, et al. Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice. Nat Neurosci. 2024;27:1505-1521 pubmed publisher
Uapinyoying P, Hogarth M, Battacharya S, M xe1 zala D, Panchapakesan K, B xf6 nnemann C, et al. Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle. iScience. 2023;26:107479 pubmed publisher
Engavale M, Hernandez C, Infante A, LeRoith T, Radovan E, Evans L, et al. Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice. bioRxiv. 2023;: pubmed publisher
Khazaei S, Chen C, Andrade A, Kabir N, Azarafshar P, Morcos S, et al. Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Cell. 2023;186:1162-1178.e20 pubmed publisher
Stym Popper G, Matta K, Chaigneau T, Rupra R, Demetriou A, Fouquet S, et al. Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology. J Neuroinflammation. 2023;20:64 pubmed publisher
Linde I, Prestwood T, Qiu J, Pilarowski G, Linde M, Zhang X, et al. Neutrophil-activating therapy for the treatment of cancer. Cancer Cell. 2023;41:356-372.e10 pubmed publisher
Aung A, Cui A, Maiorino L, Amini A, Gregory J, Bukenya M, et al. Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science. 2023;379:eabn8934 pubmed publisher
Salarian M, Ghim M, Toczek J, Han J, Weiss D, Spronck B, et al. Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity. Circ Res. 2023;132:432-448 pubmed publisher
Liu X, Sun D, Zheng M, Li X, Niu H, Zhang L, et al. Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes. Neural Regen Res. 2023;18:141-149 pubmed publisher
Peng L, Liu S, Xu J, Xie W, Fang X, Xia T, et al. Metformin alleviates prolonged isoflurane inhalation induced cognitive decline via reducing neuroinflammation in adult mice. Int Immunopharmacol. 2022;109:108903 pubmed publisher
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh J, Thomsen E, et al. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Mol Neurodegener. 2022;17:41 pubmed publisher
Ono M, Komatsu M, Ji B, Takado Y, Shimojo M, Minamihisamatsu T, et al. Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy. Aging Cell. 2022;21:e13615 pubmed publisher
Chen X, Wu D, Wu H, Li H, Yang C, Su H, et al. Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway. Lupus Sci Med. 2022;9: pubmed publisher
Liu H, Wilson K, Firth A, Macri C, Schriek P, Blum A, et al. Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86. Nat Commun. 2022;13:1934 pubmed publisher
Zein H, Abou Samra E, Scur M, Gutsol A, Hall C, Dasgupta B, et al. Clr-f expression regulates kidney immune and metabolic homeostasis. Sci Rep. 2022;12:4834 pubmed publisher
Schriek P, Ching A, Moily N, Moffat J, Beattie L, Steiner T, et al. Marginal zone B cells acquire dendritic cell functions by trogocytosis. Science. 2022;375:eabf7470 pubmed publisher
Kajitani G, Brace L, Treviño Villarreal J, Trocha K, MacArthur M, Vose S, et al. Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model. Aging (Albany NY). 2021;13:22710-22731 pubmed publisher
Yang L, Li N, Yang D, Chen A, Tang J, Jing Y, et al. CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation. Cell Death Differ. 2021;: pubmed publisher
Lee S, Meilandt W, Xie L, Gandham V, Ngu H, Barck K, et al. Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology. Neuron. 2021;109:1283-1301.e6 pubmed publisher
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed publisher
Holland Tummillo K, Shoudy L, STEINER D, Kumar S, Rosa S, Namjoshi P, et al. Autotransporter-Mediated Display of Complement Receptor Ligands by Gram-Negative Bacteria Increases Antibody Responses and Limits Disease Severity. Pathogens. 2020;9: pubmed publisher
Ge Y, Zhang S, Wang J, Xia F, Wan J, Lu J, et al. Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity. FASEB J. 2020;34:6920-6933 pubmed publisher
Sun D, Sun P, He S, Shi M. Rat IgG mediated circulatory cell depletion in mice requires mononuclear phagocyte system and is facilitated by complement. J Leukoc Biol. 2020;107:529-539 pubmed publisher
Ren Y, Zhang B, Zhao X, Zhang Z. Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria. J Neurochem. 2020;: pubmed publisher
Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, et al. GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway. Chem Biol Interact. 2019;316:108926 pubmed publisher
Campbell S, Muñoz Ballester C, Chaunsali L, Mills W, Yang J, Sontheimer H, et al. Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes. Neurochem Int. 2020;133:104628 pubmed publisher
Romp E, Arakandy V, Fischer J, Wolz C, Siegmund A, Löffler B, et al. Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis. Cell Mol Life Sci. 2019;: pubmed publisher
Wu T, Dejanovic B, Gandham V, Gogineni A, Edmonds R, Schauer S, et al. Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy. Cell Rep. 2019;28:2111-2123.e6 pubmed publisher
Sharba S, Venkatakrishnan V, Padra M, Winther M, Gabl M, Sundqvist M, et al. Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium infection. Virulence. 2019;10:610-624 pubmed publisher
Peters E, Tsihlis N, Karver M, Chin S, Musetti B, Ledford B, et al. Atheroma Niche-Responsive Nanocarriers for Immunotherapeutic Delivery. Adv Healthc Mater. 2019;8:e1801545 pubmed publisher
Medler T, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth A, et al. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018;34:561-578.e6 pubmed publisher
Ho C, Ismail N, Koh J, Gunaseelan S, Low Y, Ng Y, et al. Localisation of Formyl-Peptide Receptor 2 in the Rat Central Nervous System and Its Role in Axonal and Dendritic Outgrowth. Neurochem Res. 2018;43:1587-1598 pubmed publisher
Motwani M, Colas R, George M, Flint J, Dalli J, Richard Loendt A, et al. Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation. JCI Insight. 2018;3: pubmed publisher
Horibe K, Hosoya A, Hiraga T, Nakamura H. Expression and localization of CRAMP in rat tooth germ and during reparative dentin formation. Clin Oral Investig. 2018;22:2559-2566 pubmed publisher
Lee S, Lee P, Kim B, Seo H, Baek A, Park J, et al. Annexin A1 in plasma from patients with bronchial asthma: its association with lung function. BMC Pulm Med. 2018;18:1 pubmed publisher
Lappas M, McCracken S, McKelvey K, Lim R, James J, Roberts C, et al. Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction. Mol Hum Reprod. 2018;24:94-109 pubmed publisher
Wang H, Anthony D, Yatmaz S, Wijburg O, Satzke C, Levy B, et al. Aspirin-triggered resolvin D1 reduces pneumococcal lung infection and inflammation in a viral and bacterial coinfection pneumonia model. Clin Sci (Lond). 2017;131:2347-2362 pubmed publisher
Tan J, Tan Y, Muljadi R, Chan S, Lau S, Mockler J, et al. Amnion Epithelial Cells Promote Lung Repair via Lipoxin A4. Stem Cells Transl Med. 2017;6:1085-1095 pubmed publisher
Huang P, Zhou Y, Liu Z, Zhang P. Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4+ T Cells. Mediators Inflamm. 2016;2016:1701059 pubmed
Hodges R, Li D, Shatos M, Serhan C, Dartt D. Lipoxin A4 Counter-regulates Histamine-stimulated Glycoconjugate Secretion in Conjunctival Goblet Cells. Sci Rep. 2016;6:36124 pubmed publisher
Maehara N, Arai S, Mori M, Iwamura Y, Kurokawa J, Kai T, et al. Circulating AIM prevents hepatocellular carcinoma through complement activation. Cell Rep. 2014;9:61-74 pubmed publisher
product information
master code :
NB200-540
SKU :
NB200-540
product name :
Complement C3 Antibody (11H9) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Complement C3 Antibody (11H9) - BSA Free from Novus is a rat monoclonal antibody to Complement C3. This antibody reacts with bacteria - escherichia coli,e. coli,mouse. The Complement C3 Antibody (11H9) - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunohistochemistry-Paraffin,Immunoassay,Flow (Intracellular),CyTOF-ready.
target :
Complement C3
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
11H9
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rat
immunogen :
This Complement C3 Antibody (11H9) was developed against C57BL/6 thymocytes saturated with rat anti-Thy-1 monoclonal antibody of IgG2b subclass (RmT1).
isotype :
IgG2a
purity :
Protein G purified
species :
Bacteria - Escherichia coli,E. coli,Mouse
specificity :
Mouse Complement C3 and its activation products, C3b, iC3b, C3d and C3dg
theoretical molecular weight :
187 kDa
gene symbol :
C3
Antibody validation :
Biological Validation
accessionNumbers :
P01027
applications :
Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoassay,Flow (Intracellular),CyTOF-ready
USD :
469 USD
alt names :
Acylation Stimulating Protein, acylation-stimulating protein cleavage product, AHUS5, ARMD9, ASP, C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a, C3a anaphylatoxin, C3adesArg, C3b, C3bc, C3-beta-c, complement C3, Complement C3 alpha chain, Complement C3 beta chain, Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, Complement C3d fragment, Complement C3dg fragment, Complement C3f fragment, Complement C3g fragment, complement component 3, complement component C3, complement component C3a, complement component C3b, CPAMD1, EC 3.4.21.43, epididymis secretory sperm binding protein Li 62p, HEL-S-62p, prepro-C3
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.