CUGBP1/CELF1 Antibody (3B1) - BSA Free | Novus Biologicals NB200-316 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CUGBP1/CELF1 Antibody (3B1) - BSA Free

catalog :

NB200-316

quantity :

0.1 ml (also 0.025 ml)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B1

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, EMSA, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 13

Reference
Xiong L, Gong Y, Liu H, Huang L, Zeng Z, Zheng X, et al. circGlis3 promotes β-cell dysfunction by binding to heterogeneous nuclear ribonucleoprotein F and encoding Glis3-348aa protein. iScience. 2024;27:108680 pubmed publisher
Markmiller S, Sathe S, Server K, Nguyen T, Fulzele A, Cody N, et al. Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress. Cell Rep. 2021;36:109685 pubmed publisher
de Haro M, Al Ramahi I, Jones K, Holth J, Timchenko L, Botas J. Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy. PLoS Genet. 2013;9:e1003445 pubmed publisher
Xiao Q, Ford A, Xu J, Yan P, Lee K, Gonzales E, et al. Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia. J Neurosci. 2012;32:13587-96 pubmed
Ward A, Rimer M, Killian J, Dowling J, Cooper T. CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Hum Mol Genet. 2010;19:3614-22 pubmed publisher
Hashem V, Galloway J, Mori M, Willemsen R, Oostra B, Paylor R, et al. Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet. 2009;18:2443-51 pubmed publisher
Orengo J, Chambon P, Metzger D, Mosier D, Snipes G, Cooper T. Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci U S A. 2008;105:2646-51 pubmed publisher
Kress C, Gautier Courteille C, Osborne H, Babinet C, Paillard L. Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice. Mol Cell Biol. 2007;27:1146-57 pubmed
Lin X, Miller J, Mankodi A, Kanadia R, Yuan Y, Moxley R, et al. Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy. Hum Mol Genet. 2006;15:2087-97 pubmed
Mankodi A, Lin X, Blaxall B, Swanson M, Thornton C. Nuclear RNA foci in the heart in myotonic dystrophy. Circ Res. 2005;97:1152-5 pubmed
Mankodi A, Teng Umnuay P, Krym M, Henderson D, Swanson M, Thornton C. Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2. Ann Neurol. 2003;54:760-8 pubmed
Savkur R, Philips A, Cooper T. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nat Genet. 2001;29:40-7 pubmed
Good P, Chen Q, Warner S, Herring D. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. J Biol Chem. 2000;275:28583-92 pubmed

product information

master code :

NB200-316

SKU :

NB200-316

product name :

CUGBP1/CELF1 Antibody (3B1) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The CUGBP1/CELF1 Antibody (3B1) - BSA Free from Novus is a mouse monoclonal antibody to CUGBP1/CELF1. This antibody reacts with bovine,human,mouse,porcine,primate,rabbit,rat. The CUGBP1/CELF1 Antibody (3B1) - BSA Free has been validated for the following applications: EMSA,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Gel Super Shift Assays,Simple Western.

target :

CUGBP1/CELF1

category :

Primary Antibodies

buffer :

Tris-Glycine and 0.15M NaCl

clonality :

Monoclonal

clone :

3B1

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full-length human CUGBP1 [UniProt# Q92879]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Bovine,Human,Mouse,Porcine,Primate,Rabbit,Rat

theoretical molecular weight :

50 kDa

gene symbol :

CELF1

accessionNumbers :

Q92879

applications :

EMSA,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Gel Super Shift Assays,Simple Western

USD :

459 USD

alt names :

BRUNOL250 kDa nuclear polyadenylated RNA-binding protein, bruno-like 2, Bruno-like protein 2, CUG RNA-binding protein, CUG triplet repeat, RNA binding protein 1, CUG triplet repeat, RNA-binding protein 1, CUG-BP, CUG-BP- and ETR-3-like factor 1, CUGBP Elav-like family member 1, CUGBP, Elav-like family member 1, CUGBP1CUG triplet repeat RNA-binding protein 1, CUGBPCELF-1, Deadenylation factor CUG-BP, EDEN-BP, EDEN-BP homolog, embryo deadenylation element binding protein, Embryo deadenylation element-binding protein homolog, hNab50, NAB50CUG-BP1, NAPOR, nuclear polyadenylated RNA-binding protein, 50-kD, RNA-binding protein BRUNOL-2

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage