ER beta/NR3A2 Antibody (6A12) - Azide and BSA Free | Novus Biologicals NB200-303 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

ER beta/NR3A2 Antibody (6A12) - Azide and BSA Free

catalog :

NB200-303

quantity :

100 ul

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A12

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 15

Reference
Asavasupreechar T, Chan M, Saito R, Miki Y, Boonyaratanakornkit V, Sasano H. Sex steroid metabolism and actions in non-small cell lung carcinoma. J Steroid Biochem Mol Biol. 2019;193:105440 pubmed publisher
Andersson S, Sundberg M, Pristovšek N, Ibrahim A, Jonsson P, Katona B, et al. Insufficient antibody validation challenges oestrogen receptor beta research. Nat Commun. 2017;8:15840 pubmed publisher
Vivar O, Zhao X, Saunier E, Griffin C, Mayba O, Tagliaferri M, et al. Estrogen receptor beta binds to and regulates three distinct classes of target genes. J Biol Chem. 2010;285:22059-66 pubmed publisher
Vivar O, Saunier E, Leitman D, Firestone G, Bjeldanes L. Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane. Endocrinology. 2010;151:1662-7 pubmed publisher
Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 pubmed publisher
Klinge C, Wickramasinghe N, Ivanova M, Dougherty S. Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. FASEB J. 2008;22:2185-97 pubmed publisher
Cvoro A, Paruthiyil S, Jones J, Tzagarakis Foster C, Clegg N, Tatomer D, et al. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 2007;148:538-47 pubmed
Cvoro A, Tzagarakis Foster C, Tatomer D, Paruthiyil S, Fox M, Leitman D. Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol Cell. 2006;21:555-64 pubmed
Hopp T, Weiss H, Parra I, Cui Y, Osborne C, Fuqua S. Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer. Clin Cancer Res. 2004;10:7490-9 pubmed
Tee M, Rogatsky I, Tzagarakis Foster C, Cvoro A, An J, Christy R, et al. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol Biol Cell. 2004;15:1262-72 pubmed
Speirs V. Correspondence re: S. A. W. Fuqua et al., Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Res.,63: 2434-2439, 2003. Cancer Res. 2003;63:9055 pubmed
Konstantinopoulos P, Kominea A, Vandoros G, Sykiotis G, Andricopoulos P, Varakis I, et al. Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation. Eur J Cancer. 2003;39:1251-8 pubmed
Bianco N, Perry G, Smith M, Templeton D, Montano M. Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol. 2003;17:1344-55 pubmed
Saji S, Omoto Y, Shimizu C, Warner M, Hayashi Y, Horiguchi S, et al. Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor. Cancer Res. 2002;62:4849-53 pubmed
Speirs V, Skliris G, Burdall S, Carder P. Distinct expression patterns of ER alpha and ER beta in normal human mammary gland. J Clin Pathol. 2002;55:371-4 pubmed

product information

master code :

NB200-303

SKU :

NB200-303

product name :

ER beta/NR3A2 Antibody (6A12) - Azide and BSA Free

unit size :

100 ul

description :

The ER beta/NR3A2 Antibody (6A12) - Azide and BSA Free from Novus is a mouse monoclonal antibody to ER beta/NR3A2. This antibody reacts with human. The ER beta/NR3A2 Antibody (6A12) - Azide and BSA Free has been validated for the following applications: Chemotaxis,IF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence.

target :

ER beta/NR3A2

category :

Primary Antibodies

buffer :

PBS (pH 7.4)

clonality :

Monoclonal

clone :

6A12

conjugate :

Unconjugated

host :

Mouse

immunogen :

Amino acids 1-153 of human ER beta/NR3A2 expressed in E. coli.

isotype :

IgG2a

purity :

Protein G purified

species :

Human

specificity :

This is specific for Estrogen receptor-Beta

theoretical molecular weight :

55 kDa

gene symbol :

ESR2

applications :

Chemotaxis,IF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence

USD :

449 USD

alt names :

Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage