15-PGDH/HPGD Antibody | Novus Biologicals NB200-179 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

15-PGDH/HPGD Antibody

catalog :

NB200-179

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 8

Reference
Ghatak S, Mehrabi S, Mehdawi L, Satapathy S, Sjölander A. Identification of a Novel Five-Gene Signature as a Prognostic and Diagnostic Biomarker in Colorectal Cancers. Int J Mol Sci. 2022;23: pubmed publisher
Volpato M, Cummings M, Shaaban A, Abderrahman B, Hull M, Maximov P, et al. Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer. Explor Target Antitumor Ther. 2020;1:355-371 pubmed publisher
Corwin C, Nikolopoulou A, Pan A, Nunez Santos M, Vallabhajosula S, Serrano P, et al. Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets. J Neuroinflammation. 2018;15:272 pubmed publisher
Yao L, Chen W, Song K, Han C, Gandhi C, Lim K, et al. 15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury. PLoS ONE. 2017;12:e0176106 pubmed publisher
Mehdawi L, Satapathy S, Gustafsson A, Lundholm K, Alvarado Kristensson M, Sjölander A. A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells. Oncotarget. 2017;8:35033-35047 pubmed publisher
Loo T, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, et al. Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity. Cancer Discov. 2017;7:522-538 pubmed publisher
Prima V, Kaliberova L, Kaliberov S, Curiel D, Kusmartsev S. COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells. Proc Natl Acad Sci U S A. 2017;114:1117-1122 pubmed publisher
Miyagishi H, Kosuge Y, Takano A, Endo M, Nango H, Yamagata Murayama S, et al. Increased Expression of 15-Hydroxyprostaglandin Dehydrogenase in Spinal Astrocytes During Disease Progression in a Model of Amyotrophic Lateral Sclerosis. Cell Mol Neurobiol. 2017;37:445-452 pubmed publisher

image

image 1 :

Simple Western: 15-PGDH/HPGD Antibody [NB200-179] - Simple Western lane view shows a specific band for 15-PGDH/HPGD in 0.5 mg/ml of Lovo (left) and HeLa (right) lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB200-179

SKU :

NB200-179

product name :

15-PGDH/HPGD Antibody

description :

The 15-PGDH/HPGD Antibody from Novus Biologicals is a rabbit polyclonal antibody to 15-PGDH/HPGD. This antibody reacts with human,mouse,rat. The 15-PGDH/HPGD Antibody has been validated for the following applications: Immunohistochemistry,Simple Western,Knockdown Validated,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.

target :

15-PGDH/HPGD

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS (pH 7.4)

clonality :

Polyclonal

concentration :

2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Purified type I human placental 15-PGDH protein [UniProt# P15428]

isotype :

IgG

purity :

Protein A purified

species :

Human,Mouse,Rat

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

gene symbol :

HPGD

Antibody validation :

Biological Validation

applications :

Immunohistochemistry,Simple Western,Knockdown Validated,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

15-hydroxyprostaglandin dehydrogenase [NAD+], 15-PGDH, EC 1.1.1, EC 1.1.1.141, hydroxyprostaglandin dehydrogenase 15-(NAD), NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, PGDH1PGDH, Prostaglandin dehydrogenase 1, SDR36C1, short chain dehydrogenase/reductase family 36C, member 1

more info or order :

Novus Biologicals product webpage