p19ARF/CDKN2A Antibody (12-A1-1) | Novus Biologicals NB200-169 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

p19ARF/CDKN2A Antibody (12-A1-1)

catalog :

NB200-169

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

12-A1-1

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 6

Reference
Guo Y, Chomiak A, Hong Y, Lowe C, Kopsidas C, Chan W, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022;25:104519 pubmed publisher
Roselló Díez A, Madisen L, Bastide S, Zeng H, Joyner A. Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice. PLoS Biol. 2018;16:e2005086 pubmed publisher
Zhang X, Hagen J, Muniz V, Smith T, Coombs G, Eischen C, et al. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. PLoS ONE. 2013;8:e80228 pubmed publisher
Apicelli A, Maggi L, Hirbe A, Miceli A, Olanich M, Schulte Winkeler C, et al. A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function. Mol Cell Biol. 2008;28:1068-80 pubmed
Hernando E, Charytonowicz E, Dudas M, Menendez S, Matushansky I, Mills J, et al. The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nat Med. 2007;13:748-53 pubmed
Klochendler Yeivin A, Picarsky E, Yaniv M. Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex. Mol Cell Biol. 2006;26:2661-74 pubmed

image

image 1 :

Western Blot: p19ARF/CDKN2A Antibody (12-A1-1) [NB200-169] - Analysis of endogenous p19Arf using NB200-169. Total cell lysates (25 ug) from NIH3T3 cells, which have deleted the Arf gene (Lanes 1) and from wild type mouse embryo fibroblasts (MEFs) at passage 6, which express p19Arf (Lanes 2), were resolved by SDS-PAGE. The membrane was probed with 1ug/ml purified p19Arf (NB200-169).

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB200-169

SKU :

NB200-169

product name :

p19ARF/CDKN2A Antibody (12-A1-1)

description :

The p19ARF/CDKN2A Antibody (12-A1-1) from Novus Biologicals is a rat monoclonal antibody to p19ARF/CDKN2A. This antibody reacts with hamster (negative),human (negative),mouse. The p19ARF/CDKN2A Antibody (12-A1-1) has been validated for the following applications: ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot.

target :

p19ARF/CDKN2A

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

12-A1-1

conjugate :

Unconjugated

host :

Rat

immunogen :

A synthetic peptide made to a sequence (within residues 1-100) of mouse p19ARF/CDKN2A. [UniProt# Q64364]

isotype :

IgG2b

purity :

Unpurified

species :

Hamster (Negative),Human (Negative),Mouse

specificity :

This antibody is specific for murine p19ARF/CDKN2A

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

theoretical molecular weight :

19 kDa

gene symbol :

Cdkn2a

accessionNumbers :

Q64364

applications :

ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot

USD :

399

USD 2025 :

409 USD

alt names :

alternative reading frame, ARF, ARF-INK4a, CDK4I, CDKN2A, Cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, INK4, INK4a, Ink4a/Arf, INK4a-ARF, mitochondrial smARF', MTS1, p14, p14ARF, P16, p16(INK4a), p16-INK4, p16INK4a, p16-INK4a, P19, p19 ARF , p19ARF, Pctr1

more info or order :

Novus Biologicals product webpage