MMP-2 Antibody (8B4) - (Pro and Active) - BSA Free | Novus Biologicals NB200-114 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MMP-2 Antibody (8B4) - (Pro and Active) - BSA Free

catalog :

NB200-114

quantity :

0.1 ml (also 0.025 ml)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8B4

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 33

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 2a	Thompson P, Shah A, Ntranos V, Van Gool F, Atkinson M, Bhushan A. Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes. Cell Metab. 2019;29:1045-1060.e10 pubmed publisher
western blot; mouse	Siddesha J, Valente A, Yoshida T, Sakamuri S, Delafontaine P, Iba H, et al. Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration. Cell Signal. 2014;26:933-41 pubmed publisher
western blot; human	Huang L, Cai Y, Lung I, Leung B, Burd A. A study of the combination of triamcinolone and 5-fluorouracil in modulating keloid fibroblasts in vitro. J Plast Reconstr Aesthet Surg. 2013;66:e251-9 pubmed publisher
western blot; mouse	Raaf L, Noll C, Cherifi M, Samuel J, Delcayre C, Delabar J, et al. Myocardial fibrosis and TGFB expression in hyperhomocysteinemic rats. Mol Cell Biochem. 2011;347:63-70 pubmed publisher
immunocytochemistry; rat immunohistochemistry; rat	von Leithner P, Ciurtin C, Jeffery G. Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery. Mol Vis. 2010;16:570-81 pubmed
immunohistochemistry - paraffin section; mouse immunohistochemistry; mouse	Locke N, Royce S, Wainewright J, Samuel C, Tang M. Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease. Am J Respir Cell Mol Biol. 2007;36:625-32 pubmed
immunohistochemistry - paraffin section; human immunohistochemistry; human	Ribeiro Silva A, Ribeiro do Vale F, Zucoloto S. Vascular endothelial growth factor expression in the basal subtype of breast carcinoma. Am J Clin Pathol. 2006;125:512-8 pubmed
immunocytochemistry; human	Wang X, Yu D, McCaughan G, Gorrell M. Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line. Hepatology. 2005;42:935-45 pubmed
immunohistochemistry - paraffin section; human immunohistochemistry; human	Dong B, Sato M, Sakurada A, Sagawa M, Endo C, Wu S, et al. Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation. J Thorac Cardiovasc Surg. 2005;130:733-9 pubmed
western blot; human	Alcorn J, Fierer J, Chojkier M. The acute-phase response protects mice from D-galactosamine sensitization to endotoxin and tumor necrosis factor-alpha. Hepatology. 1992;15:122-9 pubmed
	Thi T, Thanh H, Nguyen V, Kwon S, Moon C, Hwang E, et al. Complement regulatory protein CD46 promotes bladder cancer metastasis through activation of MMP9. Int J Oncol. 2024;65: pubmed publisher
	Sun D, Huang H, Chou C, Cheng L, Wang W, Tian Y, et al. Punicalagin is cytotoxic to human colon cancer cells by modulating cell proliferation, apoptosis, and invasion. Hum Exp Toxicol. 2023;42:9603271231213979 pubmed publisher
	Saha D, Mitra D, Alam N, Sen S, Mustafi S, Majumder P, et al. Lupeol and Paclitaxel cooperate in hindering hypoxia induced vasculogenic mimicry via suppression of HIF-1α-EphA2-Laminin-5γ2 network in human oral cancer. J Cell Commun Signal. 2023;17:591-608 pubmed publisher
	Gerwinn T, Salemi S, Schori L, Planta D, Eberli D, Horst M. Improved contractile potential in detrusor microtissues from pediatric patients with end stage lower urinary tract dysfunction. Front Cell Dev Biol. 2022;10:1007265 pubmed publisher
	Neff L, Zhang Y, Van Laer A, Baicu C, Karavan M, Zile M, et al. Mechanisms that limit regression of myocardial fibrosis following removal of left ventricular pressure overload. Am J Physiol Heart Circ Physiol. 2022;323:H165-H175 pubmed publisher
	Diaconu G, Mihalache C, Popescu G, Man G, Rusu R, Toader C, et al. Clinical and pathological considerations in lumbar herniated disc associated with inflammatory lesions. Rom J Morphol Embryol. 2021;62:951-960 pubmed publisher
	Damerell V, Ambele M, Salisbury S, Neumann Mufweba A, Durandt C, Pepper M, et al. The c-Myc/TBX3 Axis Promotes Cellular Transformation of Sarcoma-Initiating Cells. Front Oncol. 2021;11:801691 pubmed publisher
	Kollaras V, Valsami G, Lambropoulou M, Konstandi O, Kostomistsopoulos N, Pikoulis E, et al. Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury in an experimental rat model. Acta Cir Bras. 2021;36:e360904 pubmed publisher
	Preda S, Predescu A, Stoica L, Albulescu D, Ionovici N, Bugălă N, et al. Histopathological and immunohistochemical changes of the marginal periodontium in patients with Turner syndrome. Rom J Morphol Embryol. 2021;62:239-247 pubmed publisher
	Betsou A, Lambropoulou M, Georgakopoulou A, Kostomitsopoulos N, Konstandi O, Anagnostopoulos K, et al. The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR. J Pharm Pharmacol. 2021;: pubmed publisher
	Marini C, Cossu V, Bonifacino T, Bauckneht M, Torazza C, Bruno S, et al. Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis. EJNMMI Res. 2020;10:76 pubmed publisher
	Perek B, Kowalska K, Kempisty B, Nawrocki M, Nowicki M, Puślecki M, et al. Infiltration of CD68+ cells correlates positively with matrix metalloproteinase 2 expression in the arteries used as aortocoronary bypass grafts. Possible clinical implications. Cardiol J. 2019;: pubmed publisher
	Shang S, Ji X, Zhang L, Chen J, Li C, Shi R, et al. Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis. Cancer Res. 2019;79:5513-5526 pubmed publisher
	Plastira I, Bernhart E, Goeritzer M, DeVaney T, Reicher H, Hammer A, et al. Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype. J Neuroinflammation. 2017;14:253 pubmed publisher
	Gallego MuÃ±oz P, Ibares FrÃas L, Lorenzo E, Marcos S, PerÃ©z Merino P, Bekesi N, et al. Corneal Wound Repair After Rose Bengal and Green Light Crosslinking: Clinical and Histologic Study. Invest Ophthalmol Vis Sci. 2017;58:3471-3480 pubmed publisher
	Amos P, Fung S, Case A, Kifelew J, Osnis L, Smith C, et al. Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells. ASN Neuro. 2017;9:1759091417716610 pubmed publisher
	Erikson J, Valente A, Mummidi S, Kandikattu H, Demarco V, Bender S, et al. Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling. J Biol Chem. 2017;292:2345-2358 pubmed publisher
	Plastira I, Bernhart E, Goeritzer M, Reicher H, Kumble V, Kogelnik N, et al. 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype. J Neuroinflammation. 2016;13:205 pubmed publisher
	Sakamuri S, Valente A, Siddesha J, Delafontaine P, Siebenlist U, Gardner J, et al. TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis. Mol Cell Endocrinol. 2016;429:84-92 pubmed publisher
	Kim J, Joo S, Sunwoo J, Kim E, Kim M, Tchah H. Lower energy to make a corneal flap with a 60 kHz femtosecond laser reduces flap inflammation and corneal stromal cell death but weakens flap adhesion. Korean J Ophthalmol. 2013;27:120-5 pubmed publisher
	Qian J, Dong A, Kong M, Ma Z, Fan J, Jiang G. Suppression of type 1 Insulin-like growth factor receptor expression by small interfering RNA inhibits A549 human lung cancer cell invasion in vitro and metastasis in xenograft nude mice. Acta Biochim Biophys Sin (Shanghai). 2007;39:137-47 pubmed
	McLellan A, Kapp M, Eggert A, Linden C, Bommhardt U, Brocker E, et al. Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression. Blood. 2002;99:2084-93 pubmed
	Welt F, Edelman E, Simon D, Rogers C. Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries. Arterioscler Thromb Vasc Biol. 2000;20:2553-8 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB200-114

SKU :

NB200-114

product name :

MMP-2 Antibody (8B4) - (Pro and Active) - BSA Free

description :

The MMP-2 Antibody (8B4) - (Pro and Active) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to MMP-2. This antibody reacts with human,mouse,rat. The MMP-2 Antibody (8B4) - (Pro and Active) - BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.

target :

MMP-2

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

8B4

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Activated recombinant human MMP-2. [Uniprot: P08253]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human,Mouse,Rat

specificity :

This is specific for pro and active MMP2

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

gene symbol :

MMP2

applications :

ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence

USD :

449

USD 2025 :

459 USD

alt names :

72 kDa gelatinase, CLG4, CLG4A72 kDa type IV collagenase, collagenase type IV-A, EC 3.4.24, EC 3.4.24.24, Gelatinase A, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase), matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IVcollagenase), Matrix metalloproteinase-2, matrix metalloproteinase-II, MMP-2, MMP-II, MONA, neutrophil gelatinase, TBE-1matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)

more info or order :

Novus Biologicals product webpage