This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TSG101 Antibody (4A10)
catalog :
NB200-112
quantity :
0.1 ml
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
Alexa Fluor 532
clone name :
4A10
reactivity :
human, mouse, rat, dogs, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 95
Reference |
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Zhang L, Li R, Geng R, Wang L, Chen X, Qiao S, et al. Tumor Susceptibility Gene 101 (TSG101) Contributes to Virion Formation of Porcine Reproductive and Respiratory Syndrome Virus via Interaction with the Nucleocapsid (N) Protein along with the Early Secretory Pathway. J Virol. 2022;96:e0000522 pubmed publisher
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Shibata H, Suzuki H, Kakiuchi T, Inuzuka T, Yoshida H, Mizuno T, et al. Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants. J Biol Chem. 2008;283:9623-32 pubmed publisher
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Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher E, et al. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J Cell Biol. 2007;179:485-500 pubmed
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Fraile Ramos A, Pelchen Matthews A, Risco C, Rejas M, Emery V, Hassan Walker A, et al. The ESCRT machinery is not required for human cytomegalovirus envelopment. Cell Microbiol. 2007;9:2955-67 pubmed
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Young T, Rosen D, Mei F, Li N, Liu J, Wang X, et al. Up-regulation of tumor susceptibility gene 101 conveys poor prognosis through suppression of p21 expression in ovarian cancer. Clin Cancer Res. 2007;13:3848-54 pubmed
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De Domenico I, Ward D, Langelier C, Vaughn M, Nemeth E, Sundquist W, et al. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell. 2007;18:2569-78 pubmed
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Tampellini D, Magrane J, Takahashi R, Li F, Lin M, Almeida C, et al. Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem. 2007;282:18895-906 pubmed
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Young T, Mei F, Rosen D, Yang G, Li N, Liu J, et al. Up-regulation of tumor susceptibility gene 101 protein in ovarian carcinomas revealed by proteomics analyses. Mol Cell Proteomics. 2007;6:294-304 pubmed
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Langelier C, von Schwedler U, Fisher R, De Domenico I, White P, Hill C, et al. Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol. 2006;80:9465-80 pubmed
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Chertova E, Chertov O, Coren L, Roser J, Trubey C, Bess J, et al. Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages. J Virol. 2006;80:9039-52 pubmed
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Raiborg C, Wesche J, Malerød L, Stenmark H. Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains. J Cell Sci. 2006;119:2414-24 pubmed
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Razi M, Futter C. Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. Mol Biol Cell. 2006;17:3469-83 pubmed
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Almeida C, Takahashi R, Gouras G. Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system. J Neurosci. 2006;26:4277-88 pubmed
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Duncan L, Piper S, Dodd R, Saville M, Sanderson C, Luzio J, et al. Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J. 2006;25:1635-45 pubmed
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Bache K, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, et al. The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. Mol Biol Cell. 2006;17:2513-23 pubmed
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Gullapalli A, Wolfe B, Griffin C, Magnuson T, Trejo J. An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. Mol Biol Cell. 2006;17:1228-38 pubmed
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Irie T, Harty R. L-domain flanking sequences are important for host interactions and efficient budding of vesicular stomatitis virus recombinants. J Virol. 2005;79:12617-22 pubmed
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Cabezas A, Bache K, Brech A, Stenmark H. Alix regulates cortical actin and the spatial distribution of endosomes. J Cell Sci. 2005;118:2625-35 pubmed
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Irie T, Licata J, Harty R. Functional characterization of Ebola virus L-domains using VSV recombinants. Virology. 2005;336:291-8 pubmed
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Ward D, Vaughn M, Shiflett S, White P, Pollock A, Hill J, et al. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. J Biol Chem. 2005;280:10548-55 pubmed
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Lin Y, Kimpler L, Naismith T, Lauer J, Hanson P. Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. J Biol Chem. 2005;280:12799-809 pubmed
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Bache K, Slagsvold T, Cabezas A, Rosendal K, Raiborg C, Stenmark H. The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. Mol Biol Cell. 2004;15:4337-46 pubmed
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Stuchell M, Garrus J, Muller B, Stray K, Ghaffarian S, McKinnon R, et al. The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. J Biol Chem. 2004;279:36059-71 pubmed
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Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, et al. Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. J Cell Biol. 2004;164:923-33 pubmed
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Zhu G, Gilchrist R, Borley N, Chng H, Morgan M, Marshall J, et al. Reduction of TSG101 protein has a negative impact on tumor cell growth. Int J Cancer. 2004;109:541-7 pubmed
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Irie T, Licata J, McGettigan J, Schnell M, Harty R. Budding of PPxY-containing rhabdoviruses is not dependent on host proteins TGS101 and VPS4A. J Virol. 2004;78:2657-65 pubmed
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Heissmeyer V, Macian F, Im S, Varma R, Feske S, Venuprasad K, et al. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol. 2004;5:255-65 pubmed
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von Schwedler U, Stuchell M, Muller B, Ward D, Chung H, Morita E, et al. The protein network of HIV budding. Cell. 2003;114:701-13 pubmed
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Strack B, Calistri A, Craig S, Popova E, Gottlinger H. AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell. 2003;114:689-99 pubmed
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Chiou C, Hu C, Chen P, Liao C, Lin Y, Wang J. Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. J Gen Virol. 2003;84:2795-805 pubmed
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Gottwein E, Bodem J, Muller B, Schmechel A, Zentgraf H, Kräusslich H. The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release. J Virol. 2003;77:9474-85 pubmed
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Bache K, Brech A, Mehlum A, Stenmark H. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J Cell Biol. 2003;162:435-42 pubmed
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Pornillos O, Higginson D, Stray K, Fisher R, Garrus J, Payne M, et al. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J Cell Biol. 2003;162:425-34 pubmed
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Zhu G, Reynolds L, Crnogorac Jurcevic T, Gillett C, Dublin E, Marshall J, et al. Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer. Oncogene. 2003;22:3742-8 pubmed
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Myers E, Allen J. Tsg101, an inactive homologue of ubiquitin ligase e2, interacts specifically with human immunodeficiency virus type 2 gag polyprotein and results in increased levels of ubiquitinated gag. J Virol. 2002;76:11226-35 pubmed
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Bishop N, Horman A, Woodman P. Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. J Cell Biol. 2002;157:91-101 pubmed
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Garrus J, von Schwedler U, Pornillos O, Morham S, Zavitz K, Wang H, et al. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 2001;107:55-65 pubmed
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product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB200-112
SKU :
NB200-112
product name :
TSG101 Antibody (4A10)
description :
The TSG101 Antibody (4A10) from Novus Biologicals is a mouse monoclonal antibody to TSG101. This antibody reacts with canine,hamster,human,monkey,mouse,porcine,primate,primate - macaca mulatta (rhesus macaque),rat,zebrafish. The TSG101 Antibody (4A10) has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Electron Microscopy,Immunohistochemistry Free-Floating,Knockdown Validated,IF/IHC,Flow Cytometry,ELISA,Immunoprecipitation,Western Blot,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence.
target :
TSG101
unit size :
0.1 ml
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
4A10
conjugate :
Unconjugated
host :
Mouse
immunogen :
Amino acids 167-374 of TSG101 protein expressed in E. coli.
isotype :
IgG1
marker :
Exosome Marker
purity :
Antigen Affinity-purified
species :
Canine,Hamster,Human,Monkey,Mouse,Porcine,Primate,Rat,Zebrafish
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
44 kDa
gene symbol :
TSG101
accessionNumbers :
Q99816
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,Electron Microscopy,Immunohistochemistry Free-Floating,Knockdown Validated,IF/IHC,Flow Cytometry,ELISA,Immunoprecipitation,Western Blot,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
449 USD
alt names :
ESCRT-I complex subunit TSG101, TSG10, tumor susceptibility gene 10, tumor susceptibility gene 101, tumor susceptibility gene 101 protein, tumor susceptibility protein, VPS23
company information

Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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