p14ARF/CDKN2A Antibody - BSA Free | Novus Biologicals NB200-111 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

p14ARF/CDKN2A Antibody - BSA Free

catalog :

NB200-111

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

26C593.2

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 55

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 3a western blot; human; loading ...; fig 3d	Repenning A, Happel D, Bouchard C, Meixner M, Verel Yilmaz Y, Raifer H, et al. PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis. EMBO J. 2021;40:e106777 pubmed publisher
	Xiong H, Yang Y, Yang K, Zhao D, Tang H, Ran X. Loss of the clock gene PER2 is associated with cancer development and altered expression of important tumor-related genes in oral cancer. Int J Oncol. 2018;52:279-287 pubmed publisher
	Crawford Parks T, Marcellus K, Langill J, Ravel Chapuis A, Michaud J, Cowan K, et al. Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events. Sci Rep. 2017;7:42342 pubmed publisher
	Guerrier T, Pochard P, Lahiri A, Youinou P, Pers J, Jamin C. TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response. J Autoimmun. 2014;51:23-9 pubmed publisher
	Belmont L, Rabbe N, Antoine M, Cathelin D, Guignabert C, Kurie J, et al. Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer. Int J Cancer. 2014;134:765-77 pubmed publisher
	Figueiredo M, Amorim I, Pinto A, Barbosa V, Pinheiro L, Deoti B, et al. Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum. BMC Immunol. 2013;14:22 pubmed publisher
	Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
	Siponen M, Kauppila J, Soini Y, Salo T. TLR4 and TLR9 are induced in oral lichen planus. J Oral Pathol Med. 2012;41:741-7 pubmed publisher
	Karim R, Meyers C, Backendorf C, Ludigs K, Offringa R, van Ommen G, et al. Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes. PLoS ONE. 2011;6:e17848 pubmed publisher
	Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed publisher
	van Gent M, Griffin B, Berkhoff E, van Leeuwen D, Boer I, Buisson M, et al. EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection. J Immunol. 2011;186:1694-702 pubmed publisher
	Myles A, Aggarwal A. Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis. Rheumatology (Oxford). 2011;50:481-8 pubmed publisher
	Schneberger D, Lewis D, Caldwell S, Singh B. Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle. Int J Exp Pathol. 2011;92:1-7 pubmed publisher
	Wang C, Cao S, Yan Y, Ying Q, Jiang T, Xu K, et al. TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients. BMC Cancer. 2010;10:415 pubmed publisher
	Booth J, Arsenault R, Napper S, Griebel P, Potter A, Babiuk L, et al. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. J Innate Immun. 2010;2:483-94 pubmed publisher
	Keestra A, de Zoete M, Bouwman L, van Putten J. Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9. J Immunol. 2010;185:460-7 pubmed publisher
	Jukkola Vuorinen A, Rahko E, Vuopala K, Desmond R, Lehenkari P, Harris K, et al. Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer. J Innate Immun. 2009;1:59-68 pubmed publisher
	Machida H, Ito S, Hirose T, Takeshita F, Oshiro H, Nakamura T, et al. Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis. Nephrol Dial Transplant. 2010;25:2530-537 pubmed publisher
	Kim Y, Park J, Brand D, Fitzpatrick E, Yi A. Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula. J Immunol. 2010;184:3145-56 pubmed publisher
	Panda A, Qian F, Mohanty S, van Duin D, Newman F, Zhang L, et al. Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010;184:2518-27 pubmed publisher
	Chentoufi A, Dasgupta G, Nesburn A, Bettahi I, Binder N, Choudhury Z, et al. Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol. 2010;17:342-53 pubmed publisher
	Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
	Zhou M, McFarland Mancini M, Funk H, Husseinzadeh N, Mounajjed T, Drew A. Toll-like receptor expression in normal ovary and ovarian tumors. Cancer Immunol Immunother. 2009;58:1375-85 pubmed publisher
	Palladino M, Savarese M, Chapman J, Dughi M, Plaska D. Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa. Am J Reprod Immunol. 2008;60:541-55 pubmed publisher
	Meneghin A, Choi E, Evanoff H, Kunkel S, Martinez F, Flaherty K, et al. TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. Histochem Cell Biol. 2008;130:979-92 pubmed publisher
	Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
	Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola F, et al. Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS. Int Immunol. 2008;20:961-70 pubmed publisher
	Ju X, Zenke M, Hart D, Clark G. CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood. 2008;112:1184-94 pubmed publisher
	Zhang Y, Davis E, Blecha F, Wilkerson M. Molecular cloning and characterization of equine Toll-like receptor 9. Vet Immunol Immunopathol. 2008;124:209-19 pubmed publisher
	Cognasse F, Hamzeh Cognasse H, Lafarge S, Chavarin P, Pozzetto B, Richard Y, et al. Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology. 2008;125:430-7 pubmed publisher
	Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
	Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, et al. Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway. J Immunol. 2008;180:4067-74 pubmed
	Pegu A, Qin S, Fallert Junecko B, Nisato R, Pepper M, Reinhart T. Human lymphatic endothelial cells express multiple functional TLRs. J Immunol. 2008;180:3399-405 pubmed
	Meng Y, Kujas M, Marie Y, Paris S, Thillet J, Delattre J, et al. Expression of TLR9 within human glioblastoma. J Neurooncol. 2008;88:19-25 pubmed publisher
	Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford). 2008;47:145-9 pubmed
	Tran N, Koch A, Berkels R, Boehm O, Zacharowski P, Baumgarten G, et al. Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol Metab. 2007;92:2773-83 pubmed
	Kindrachuk J, Potter J, Brownlie R, Ficzycz A, Griebel P, Mookherjee N, et al. Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9. J Biol Chem. 2007;282:13944-53 pubmed
	Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
	Ewaschuk J, Backer J, Churchill T, Obermeier F, Krause D, Madsen K. Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect Immun. 2007;75:2572-9 pubmed
	Palladino M, Johnson T, Gupta R, Chapman J, Ojha P. Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biol Reprod. 2007;76:958-64 pubmed
	Lee J, Mo J, Katakura K, Alkalay I, Rucker A, Liu Y, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol. 2006;8:1327-36 pubmed
	Niessner A, Sato K, Chaikof E, Colmegna I, Goronzy J, Weyand C. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation. 2006;114:2482-9 pubmed
	Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed
	Gottenberg J, Cagnard N, Lucchesi C, Letourneur F, Mistou S, Lazure T, et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci U S A. 2006;103:2770-5 pubmed
	Martin Armas M, Simon Santamaria J, Pettersen I, Moens U, Smedsrød B, Sveinbjørnsson B. Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. J Hepatol. 2006;44:939-46 pubmed
	Lee J, Wu C, Lee K, Chuang T, Katakura K, Liu Y, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103:1828-33 pubmed
	Damiano V, Caputo R, Bianco R, D Armiento F, Leonardi A, De Placido S, et al. Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors. Clin Cancer Res. 2006;12:577-83 pubmed
	Tabeta K, Hoebe K, Janssen E, Du X, Georgel P, Crozat K, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol. 2006;7:156-64 pubmed
	Srivastava M, Srivastava B. Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line. Leuk Res. 2005;29:813-20 pubmed
	Miller L, Sørensen O, Liu P, Jalian H, Eshtiaghpour D, Behmanesh B, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005;174:6137-43 pubmed
	Abel K, Wang Y, Fritts L, Sanchez E, Chung E, Fitzgerald Bocarsly P, et al. Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoi. Clin Diagn Lab Immunol. 2005;12:606-21 pubmed
	Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O. Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol. 2005;83:196-8 pubmed
	Greene C, Carroll T, Smith S, Taggart C, Devaney J, Griffin S, et al. TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol. 2005;174:1638-46 pubmed
	Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, et al. Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res. 2005;6:1 pubmed
	Lee H, Dunzendorfer S, Tobias P. Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation. J Biol Chem. 2004;279:10564-74 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB200-111

SKU :

NB200-111

product name :

p14ARF/CDKN2A Antibody - BSA Free

description :

The p14ARF/CDKN2A Antibody - BSA Free from Novus Biologicals is a rabbit polyclonal antibody to p14ARF/CDKN2A. This antibody reacts with human,mouse. The p14ARF/CDKN2A Antibody - BSA Free has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Knockdown Validated,IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence.

target :

p14ARF/CDKN2A

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

A synthetic peptide made to a portion of human p14ARF (between residues 50-132). [Swiss-Prot# Q8N726]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

gene symbol :

CDKN2A

Antibody validation :

Biological Validation

accessionNumbers :

Q8N726

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Knockdown Validated,IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

ARF, CDK4 inhibitor p16-INK4, CDK4IP14ARF, CDKN2, cell cycle negative regulator beta, CMM2P16-INK4A, Cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), INK4, INK4A, MLMP16INK4, MTS-1, MTS1P14, Multiple tumor suppressor 1, p14, p14ARF, p16, p16-INK4, p16INK4a, p16-INK4a, P19, p19ARF, TP16

more info or order :

Novus Biologicals product webpage