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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Collagen VI alpha 1 Antibody
catalog :
NB120-6588
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
OX26
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3b
Xu L, Humphries F, Delagic N, Wang B, Holland A, Edgar K, et al. ECSIT is a critical limiting factor for cardiac function. JCI Insight. 2021;6: pubmed publisher
Koloko Ngassie M, De Vries M, Borghuis T, Timens W, Sin D, Nickle D, et al. Age-associated differences in the human lung extracellular matrix. Am J Physiol Lung Cell Mol Physiol. 2023;324:L799-L814 pubmed publisher
Endzhievskaya S, Hsu C, Yang H, Huang H, Lin Y, Hong Y, et al. Loss of RhoE Function in Dermatofibroma Promotes Disorganized Dermal Fibroblast Extracellular Matrix and Increased Integrin Activation. J Invest Dermatol. 2023;: pubmed publisher
Hernandez P, Moreno M, Barati Z, Hutcherson C, Sathe A, Xing C, et al. Sexual Dimorphism in the Extracellular and Pericellular Matrix of Articular Cartilage. Cartilage. 2022;13:19476035221121792 pubmed publisher
Pilling D, Sahlberg K, Karhadkar T, Chen W, Gomer R. The sialidase NEU3 promotes pulmonary fibrosis in mice. Respir Res. 2022;23:215 pubmed publisher
Zhang Y, Recouvreux M, Jung M, Galenkamp K, Li Y, Zagnitko O, et al. Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness. Cancer Discov. 2021;11:1808-1825 pubmed publisher
Oikawa K, Teixeira L, Keikhosravi A, Eliceiri K, McLellan G. Microstructure and resident cell-types of the feline optic nerve head resemble that of humans. Exp Eye Res. 2020;:108315 pubmed publisher
Mondragon E, Cowdin M, Taraballi F, Minardi S, Tasciotti E, Gregory C, et al. Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties. Front Bioeng Biotechnol. 2020;8:753 pubmed publisher
De Luca M, Vecchie D, Athmanathan B, Gopalkrishna S, Valcin J, Swain T, et al. Genetic Deletion of Syndecan-4 Alters Body Composition, Metabolic Phenotypes, and the Function of Metabolic Tissues in Female Mice Fed A High-Fat Diet. Nutrients. 2019;11: pubmed publisher
Chen X, Zhang B, Liu T, Feng M, Zhang Y, Zhang C, et al. Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death. ACS Chem Neurosci. 2019;10:4824-4833 pubmed publisher
Barbariga M, Vallone F, Mosca E, Bignami F, Magagnotti C, Fonteyne P, et al. The role of extracellular matrix in mouse and human corneal neovascularization. Sci Rep. 2019;9:14272 pubmed publisher
Lionello V, Nicot A, Sartori M, Kretz C, Kessler P, Buono S, et al. Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. Sci Transl Med. 2019;11: pubmed publisher
Angenendt L, Mikesch J, Görlich D, Busch A, Arnhold I, Rudack C, et al. Stromal collagen type VI associates with features of malignancy and predicts poor prognosis in salivary gland cancer. Cell Oncol (Dordr). 2018;41:517-525 pubmed publisher
Thomas Porch C, Li J, Zanata F, Martin E, Pashos N, Genemaras K, et al. Comparative proteomic analyses of human adipose extracellular matrices decellularized using alternative procedures. J Biomed Mater Res A. 2018;106:2481-2493 pubmed publisher
Godwin A, Starborg T, Sherratt M, Roseman A, Baldock C. Defining the hierarchical organisation of collagen VI microfibrils at nanometre to micrometre length scales. Acta Biomater. 2017;52:21-32 pubmed publisher
Nygaard R, Maynard S, Schjerling P, Kjaer M, Qvortrup K, Bohr V, et al. Acquired Localized Cutis Laxa due to Increased Elastin Turnover. Case Rep Dermatol. 2016;8:42-51 pubmed publisher
Izu Y, Ezura Y, Koch M, Birk D, Noda M. Collagens VI and XII form complexes mediating osteoblast interactions during osteogenesis. Cell Tissue Res. 2016;364:623-635 pubmed publisher
Pilling D, Cox N, Vakil V, Verbeek J, Gomer R. The long pentraxin PTX3 promotes fibrocyte differentiation. PLoS ONE. 2015;10:e0119709 pubmed publisher
Couty J, Rampon C, Leveque M, Laran Chich M, Bourdoulous S, Greenwood J, et al. PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells. J Neurochem. 2007;103:793-801 pubmed
Gosk S, Vermehren C, Storm G, Moos T. Targeting anti-transferrin receptor antibody (OX26) and OX26-conjugated liposomes to brain capillary endothelial cells using in situ perfusion. J Cereb Blood Flow Metab. 2004;24:1193-204 pubmed
Cox J, Lamb J, Bal V, Butcher G, Howard J, Owen M, et al. The phenotypic and molecular characterization of Nb2 lymphoma cells activated with IL-2 and human growth hormone. Immunology. 1989;66:83-9 pubmed
Moos T, Morgan E. Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat. J Neurochem. 2001;79:119-29 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-6588
SKU :
NB120-6588
product name :
Collagen VI alpha 1 Antibody
description :
The Collagen VI alpha 1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Collagen VI alpha 1. This antibody reacts with bovine,feline,human,mouse,rat. The Collagen VI alpha 1 Antibody has been validated for the following applications: ELISA,Immunoprecipitation,Immunohistochemistry-Frozen,IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,PCR,Immunocytochemistry/ Immunofluorescence.
target :
Collagen VI alpha 1
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Collagen VI alpha 1 from human and bovine placenta (Uniprot: P12109)
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Feline,Human,Mouse,Rat
specificity :
Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues
storage :
Store at 4C short term. For extended storage, add an equal volume of glycerol, aliquot and store at -20C or below. Avoid repeated freeze-thaw cycles.
gene symbol :
COL6A1
accessionNumbers :
P12109
applications :
ELISA,Immunoprecipitation,Immunohistochemistry-Frozen,IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,PCR,Immunocytochemistry/ Immunofluorescence
USD :
399
USD 2025 :
409 USD
alt names :
Collagen 6, collagen alpha-1(VI) chain, collagen VI, alpha-1 polypeptide, collagen, type VI, alpha 1, Collagen-6, human mRNA for collagen VI alpha-1 C-terminal globular domain10alpha 1 (VI) chain (61 AA), OPLL
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.