product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Collagen IV Antibody
catalog :
NB120-6586
quantity :
0.1 mg (also 0.02 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
76B357.1
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 129
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4a
Mehta N, Li R, Zhang D, Soomro A, He J, Zhang I, et al. miR299a-5p promotes renal fibrosis by suppressing the antifibrotic actions of follistatin. Sci Rep. 2021;11:88 pubmed publisher
Root Bernstein R, Huber J, Ziehl A, Pietrowicz M. SARS-CoV-2 and Its Bacterial Co- or Super-Infections Synergize to Trigger COVID-19 Autoimmune Cardiopathies. Int J Mol Sci. 2023;24: pubmed publisher
El Naseery N, Elewa Y, El Behery E, Dessouky A. Human umbilical cord blood-derived mesenchymal stem cells restored hematopoiesis by improving radiation induced bone marrow niche remodeling in rats. Ann Anat. 2023;250:152131 pubmed publisher
Fang L, Zhou L, Kuli x107 x, Lehner M, Tamm M, Roth M. EPs® 7630 Stimulates Tissue Repair Mechanisms and Modifies Tight Junction Protein Expression in Human Airway Epithelial Cells. Int J Mol Sci. 2023;24: pubmed publisher
Kang D, Kim M, Mohamed E, Kim D, Jeong J, Kim S, et al. Regulation of uterus and placenta remodeling under high estradiol levels in gestational diabetes mellitus models†. Biol Reprod. 2023;109:215-226 pubmed publisher
Hsu Y, Chang C, Hsieh C, Huang Y, Shih Y, Chang H, et al. Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease. Int J Mol Sci. 2023;24: pubmed publisher
Fang W, Medrano M, Cote P, Portsche M, Rao V, Hong Y, et al. Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer. Front Oncol. 2023;13:1130911 pubmed publisher
Drake L, Koloko Ngassie M, Roos B, Teske J, Prakash Y. Asthmatic lung fibroblasts promote type 2 immune responses via endoplasmic reticulum stress response dependent thymic stromal lymphopoietin secretion. Front Physiol. 2023;14:1064822 pubmed publisher
Yang C, Lu C, Pan J, Zhao C, Chen Z, Qin F, et al. The role of iTr35 cells in the inflammatory response and fibrosis progression of systemic sclerosis. Rheumatology (Oxford). 2023;: pubmed publisher
Abrahamson E, Padera R, Davies J, Farrar G, Villemagne V, Dorbala S, et al. The flutemetamol analogue cyano-flutemetamol detects myocardial AL and ATTR amyloid deposits: a post-mortem histofluorescence analysis. Amyloid. 2022;:1-19 pubmed publisher
Peng M, Curry S, Liu Y, Lohawala H, Sharma G, Sharma T. The ex vivo human translaminar autonomous system to study spaceflight associated neuro-ocular syndrome pathogenesis. NPJ Microgravity. 2022;8:44 pubmed publisher
Caporarello N, Lee J, Pham T, Jones D, Guan J, Link P, et al. Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis. Nat Commun. 2022;13:4170 pubmed publisher
Lenti E, Genovese L, Bianchessi S, Maurizio A, Sain S, di Lillo A, et al. Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors. Immunity. 2022;55:606-622.e6 pubmed publisher
Xie X, Li J, Liu P, Wang M, Gao L, Wan F, et al. Chimeric Fusion between Clostridium Ramosum IgA Protease and IgG Fc Provides Long-Lasting Clearance of IgA Deposits in Mouse Models of IgA Nephropathy. J Am Soc Nephrol. 2022;33:918-935 pubmed publisher
Robertson C, Sebastian A, Hinckley A, Rios Arce N, Hynes W, Edwards S, et al. Extracellular matrix modulates T cell clearance of malignant cells in vitro. Biomaterials. 2022;282:121378 pubmed publisher
Wohlfeil S, H xe4 fele V, Dietsch B, Weller C, Sticht C, Jauch A, et al. Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment. J Transl Med. 2022;20:62 pubmed publisher
Lu C, Ortmeier S, Brudvig J, Moretti T, Cain J, Boyadjiev S, et al. Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum. Traffic. 2022;23:81-93 pubmed publisher
Ishii H, Kaneko S, Yanai K, Aomatsu A, Hirai K, Ookawara S, et al. MicroRNA Expression Profiling in Diabetic Kidney Disease. Transl Res. 2021;237:31-52 pubmed publisher
Di Cerbo A, Giusti S, Mariotti F, Spaterna A, Rossi G, Magi G. Increased Expression of Toll-Like Receptor 4 in Skin of Dogs with Discoid Lupus Erythematous (DLE). Animals (Basel). 2021;11: pubmed publisher
Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, et al. Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH. Nature. 2021;592:444-449 pubmed publisher
Oikawa K, Teixeira L, Keikhosravi A, Eliceiri K, McLellan G. Microstructure and resident cell-types of the feline optic nerve head resemble that of humans. Exp Eye Res. 2020;:108315 pubmed publisher
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadžić S, et al. NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD. Nat Metab. 2020;2:532-546 pubmed publisher
Halder A, Yadav K, Aggarwal A, Singhal N, Sandhir R. Activation of TNFR1 and TLR4 following oxygen glucose deprivation promotes mitochondrial fission in C6 astroglial cells. Cell Signal. 2020;75:109714 pubmed publisher
Wang S, Chen P, Sung Y, Huang W, Huang H, Chu P. Effect of COL4A1 Expression on the Survival of Neoadjuvant Chemotherapy Breast Cancer Patients. J Oncol. 2020;2020:5209695 pubmed publisher
Burkovetskaya M, Small R, Guo L, Buch S, Guo M. Cocaine self-administration differentially activates microglia in the mouse brain. Neurosci Lett. 2020;728:134951 pubmed publisher
Leng S, Pignatti E, Khetani R, Shah M, Xu S, Miao J, et al. β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis. Nat Commun. 2020;11:1680 pubmed publisher
Li W, Zhan M, Quan Y, Wang H, Hua S, Li Y, et al. Modulating the tumor immune microenvironment with sunitinib malate supports the rationale for combined treatment with immunotherapy. Int Immunopharmacol. 2020;81:106227 pubmed publisher
Ozbek M, Hitit M, Ergun E, Ergun L, Beyaz F, Erhan F, et al. Expression profile of Toll-like receptor 4 in rat testis and epididymis throughout postnatal development. Andrologia. 2020;52:e13518 pubmed publisher
Willemse J, Verstegen M, Vermeulen A, Schurink I, Roest H, van der Laan L, et al. Fast, robust and effective decellularization of whole human livers using mild detergents and pressure controlled perfusion. Mater Sci Eng C Mater Biol Appl. 2020;108:110200 pubmed publisher
Rodet F, Capuz A, Ozcan B, Le Beillan R, Raffo Romero A, Kobeissy F, et al. PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype. Cells. 2019;8: pubmed publisher
Evran S, Çalış F, Akkaya E, Baran O, Cevik S, Katar S, et al. The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model. Brain Res Bull. 2020;154:68-80 pubmed publisher
Zi S, Li J, Liu L, Deng C, Ao X, Chen D, et al. Dexmedetomidine-mediated protection against septic liver injury depends on TLR4/MyD88/NF-κB signaling downregulation partly via cholinergic anti-inflammatory mechanisms. Int Immunopharmacol. 2019;76:105898 pubmed publisher
Zhang S, Yang R, Shang J, Gao T, Wang R, Peng X, et al. FOXC1 up-regulates the expression of toll-like receptors in myocardial ischaemia. J Cell Mol Med. 2019;23:7566-7580 pubmed publisher
Managò A, Audrito V, Mazzola F, Sorci L, Gaudino F, Gizzi K, et al. Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation. Nat Commun. 2019;10:4116 pubmed publisher
Yang K, Lauritzen K, Olsen M, Dahl T, Ranheim T, Ahmed M, et al. Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes. J Immunol. 2019;203:1598-1608 pubmed publisher
Arya R, Arankalle V. Phenotypic analysis of monocytes and CD4+ T cells in hepatitis E patients with or without pregnancy. Hum Immunol. 2019;80:855-862 pubmed publisher
Araldi D, Bogen O, Green P, Levine J. Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming. J Neurosci. 2019;: pubmed publisher
Mehta N, Gava A, Zhang D, Gao B, Krepinsky J. Follistatin Protects against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease. Antioxid Redox Signal. 2019;: pubmed publisher
Bernardini C, Bertocchi M, Zannoni A, Salaroli R, Tubon I, Dothel G, et al. Constitutive and LPS-stimulated secretome of porcine Vascular Wall-Mesenchymal Stem Cells exerts effects on in vitro endothelial angiogenesis. BMC Vet Res. 2019;15:123 pubmed publisher
Liang L, Shao W, Shu T, Zhang Y, Xu S, Guo L, et al. Xuezhikang improves the outcomes of cardiopulmonary resuscitation in rats by suppressing the inflammation response through TLR4/NF-κB pathway. Biomed Pharmacother. 2019;114:108817 pubmed publisher
Luo Q, Cheng D, Huang C, Li Y, Lao C, Xia Y, et al. Improvement of Colonic Immune Function with Soy Isoflavones in High-Fat Diet-Induced Obese Rats. Molecules. 2019;24: pubmed publisher
MacDonald J, Takai Y, Ishihara O, Seki H, Woods D, Tilly J. Extracellular matrix signaling activates differentiation of adult ovary-derived oogonial stem cells in a species-specific manner. Fertil Steril. 2019;111:794-805 pubmed publisher
Bagratuni T, Sklirou A, Kastritis E, Liacos C, Spilioti C, Eleutherakis Papaiakovou E, et al. Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop. Sci Rep. 2019;9:3245 pubmed publisher
Wang P, Liu B, Wu M, Wei X, Sheng S, You S, et al. Moderate prenatal alcohol exposure suppresses the TLR4-mediated innate immune response in the hippocampus of young rats. Neurosci Lett. 2019;699:77-83 pubmed publisher
Zhang Z, La Placa D, Nguyen T, Kujawski M, Le K, Li L, et al. CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes. BMC Immunol. 2019;20:7 pubmed publisher
Milanesi S, Verzola D, Cappadona F, Bonino B, Murugavel A, Pontremoli R, et al. Uric acid and angiotensin II additively promote inflammation and oxidative stress in human proximal tubule cells by activation of toll-like receptor 4. J Cell Physiol. 2019;234:10868-10876 pubmed publisher
Lee J, Joo B, Nam J, Nam H, Lee W, Nam Y, et al. An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways. Front Aging Neurosci. 2018;10:269 pubmed publisher
Mukherjee P, Hough G, Chattopadhyay A, Grijalva V, O Connor E, Meriwether D, et al. Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice. J Lipid Res. 2018;59:1818-1840 pubmed publisher
Choi C, Kang T, Song J, Kim Y, Chung E, Ylaya K, et al. Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer. Sci Rep. 2018;8:12161 pubmed publisher
Trasino S, Tang X, Shevchuk M, Choi M, Gudas L. Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor ?2 Agonist. J Pharmacol Exp Ther. 2018;367:82-94 pubmed publisher
Bidne K, Kvidera S, Ross J, Baumgard L, Keating A. Impact of repeated lipopolysaccharide administration on ovarian signaling during the follicular phase of the estrous cycle in post-pubertal pigs. J Anim Sci. 2018;: pubmed publisher
Bernardini C, Zannoni A, Bertocchi M, Tubon I, Fernandez M, Forni M. Water/ethanol extract of Cucumis sativus L. fruit attenuates lipopolysaccharide-induced inflammatory response in endothelial cells. BMC Complement Altern Med. 2018;18:194 pubmed publisher
Sun L, Li M, Ma X, Zhang L, Song J, Lv C, et al. Inhibiting high mobility group box-1 reduces early spinal cord edema and attenuates astrocyte activation and aquaporin-4 expression after spinal cord injury in rats. J Neurotrauma. 2018;: pubmed publisher
Domon H, Nagai K, Maekawa T, Oda M, Yonezawa D, Takeda W, et al. Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia. Front Immunol. 2018;9:732 pubmed publisher
Rüger B, Buchacher T, Giurea A, Kubista B, Fischer M, Breuss J. Vascular Morphogenesis in the Context of Inflammation: Self-Organization in a Fibrin-Based 3D Culture System. Front Physiol. 2018;9:679 pubmed publisher
Winter C, Silvestre Roig C, Ortega Gomez A, Lemnitzer P, Poelman H, Schumski A, et al. Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metab. 2018;28:175-182.e5 pubmed publisher
Wei W, Wan H, Peng X, Zhou H, Lu Y, He Y. Antiviral effects of Ma Huang Tang against H1N1 influenza virus infection in vitro and in an ICR pneumonia mouse model. Biomed Pharmacother. 2018;102:1161-1175 pubmed publisher
Bhattacharjee P, Keyel P. Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses. Sci Rep. 2018;8:6458 pubmed publisher
Dickson M, Hager C, Al Shaibi A, Thomas P, Baumgard L, Ross J, et al. Impact of heat stress during the follicular phase on porcine ovarian steroidogenic and phosphatidylinositol-3 signaling. J Anim Sci. 2018;96:2162-2174 pubmed publisher
Chen X, Yan X, Guo L. Inhibitory effect of Patrinia on BRL-3A cell apoptosis through the TLR4/PI3K/AKT/GSK3β and TLR4/P38/JNK signaling pathways. Mol Med Rep. 2018;17:5344-5349 pubmed publisher
Nikolaou S, Hadjikypri X, Ioannou G, Elia A, Georgiades P. Functional and phenotypic distinction of the first two trophoblast subdivisions and identification of the border between them during early postimplantation: A prerequisite for understanding early patterning during placentogenesis. Biochem Biophys Res Commun. 2018;496:64-69 pubmed publisher
Sun L, Li M, Ma X, Feng H, Song J, Lv C, et al. Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-?B signaling in an IL-6-dependent manner. J Neuroinflammation. 2017;14:231 pubmed publisher
Velez D, Tsui B, Goshia T, Chute C, Han A, Carter H, et al. 3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry. Nat Commun. 2017;8:1651 pubmed publisher
Lin E, Bayarsengee U, Wang C, Chiang Y, Cheng C. The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway. Environ Toxicol. 2018;33:72-82 pubmed publisher
Bracaglia L, Messina M, Winston S, Kuo C, Lerman M, Fisher J. 3D Printed Pericardium Hydrogels To Promote Wound Healing in Vascular Applications. Biomacromolecules. 2017;18:3802-3811 pubmed publisher
Liguori R, Incensi A, De Pasqua S, Mignani R, Fileccia E, Santostefano M, et al. Skin globotriaosylceramide 3 deposits are specific to Fabry disease with classical mutations and associated with small fibre neuropathy. PLoS ONE. 2017;12:e0180581 pubmed publisher
Nakano Y, Shimazawa M, Ojino K, Izawa H, Takeuchi H, Inoue Y, et al. Toll-like receptor 4 inhibitor protects against retinal ganglion cell damage induced by optic nerve crush in mice. J Pharmacol Sci. 2017;133:176-183 pubmed publisher
Tobita K, Watanabe I, Saito M. Specific vaginal lactobacilli suppress the inflammation induced by lipopolysaccharide stimulation through downregulation of toll-like receptor 4 expression in human embryonic intestinal epithelial cells. Biosci Microbiota Food Health. 2017;36:39-44 pubmed publisher
Schöniger S, Gräfe H, Schoon H. Expression of Toll-like receptors 2, 4 and 6 in different cell populations of the equine endometrium. Vet Immunol Immunopathol. 2017;185:7-13 pubmed publisher
Camps Bossacoma M, Perez Cano F, Franch A, Untersmayr E, Castell M. Effect of a cocoa diet on the small intestine and gut-associated lymphoid tissue composition in an oral sensitization model in rats. J Nutr Biochem. 2017;42:182-193 pubmed publisher
Azuma Y, Taniguchi F, Nakamura K, Nagira K, Khine Y, Kiyama T, et al. Lipopolysaccharide promotes the development of murine endometriosis-like lesions via the nuclear factor-kappa B pathway. Am J Reprod Immunol. 2017;77: pubmed publisher
Rigo Adrover M, Franch A, Castell M, Pérez Cano F. Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life. PLoS ONE. 2016;11:e0166082 pubmed publisher
Rathod S, Tripathy A. TGF-?1 and contact mediated suppression by CD4+CD25+CD127- T regulatory cells of patients with self-limiting hepatitis E. Hum Immunol. 2016;77:1254-1263 pubmed publisher
Lin S, Kuo M, Hsiao H, Lee P. Azithromycin modulates immune response of human monocyte-derived dendritic cells and CD4+ T cells. Int Immunopharmacol. 2016;40:318-326 pubmed publisher
Szasz T, Wenceslau C, Burgess B, Nunes K, Webb R. Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes. Diabetes. 2016;65:3754-3764 pubmed
Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed publisher
Chen C, Chen C, Jian C, Lin P, Chou J, Teng H, et al. Attenuation of exercise effect on inflammatory responses via novel role of TLR4/PI3K/Akt signaling in rat splenocytes. J Appl Physiol (1985). 2016;121:870-877 pubmed publisher
Burgueño J, Barba A, Eyre E, Romero C, Neunlist M, Fernández E. TLR2 and TLR9 modulate enteric nervous system inflammatory responses to lipopolysaccharide. J Neuroinflammation. 2016;13:187 pubmed publisher
Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J. The kinetics of damage-associated molecular patterns (DAMPs) and toll-like receptors during thioacetamide-induced acute liver injury in rats. Exp Toxicol Pathol. 2016;68:471-7 pubmed publisher
Li X, Bao W, Leung C, Ma D, Zhang G, Lu A, et al. Chemical Structure and Immunomodulating Activities of an α-Glucan Purified from Lobelia chinensis Lour. Molecules. 2016;21: pubmed publisher
Okada K, Arai S, Itoh H, Adachi S, Hayashida M, Nakase H, et al. CD68 on rat macrophages binds tightly to S100A8 and S100A9 and helps to regulate the cells' immune functions. J Leukoc Biol. 2016;100:1093-1104 pubmed
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Mishima Y, Ishihara S, Oka A, Fukuba N, Oshima N, Sonoyama H, et al. Decreased Frequency of Intestinal Regulatory CD5+ B Cells in Colonic Inflammation. PLoS ONE. 2016;11:e0146191 pubmed publisher
Płóciennikowska A, Zdioruk M, Traczyk G, Świątkowska A, Kwiatkowska K. LPS-induced clustering of CD14 triggers generation of PI(4,5)P2. J Cell Sci. 2015;128:4096-111 pubmed publisher
Mehmeti M, Allaoui R, Bergenfelz C, Saal L, Ethier S, Johansson M, et al. Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer. Breast Cancer Res. 2015;17:130 pubmed publisher
Liu L, Wang Y, Cao Z, Wang M, Liu X, Gao T, et al. Up-regulated TLR4 in cardiomyocytes exacerbates heart failure after long-term myocardial infarction. J Cell Mol Med. 2015;19:2728-40 pubmed publisher
Haricharan S, Brown P. TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth. Proc Natl Acad Sci U S A. 2015;112:E3216-25 pubmed publisher
Martin I, Cabán Hernández K, Figueroa Santiago O, Espino A. Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo. J Immunol. 2015;194:3924-36 pubmed publisher
Zhu W, Zhu N, Bai D, Miao J, Zou S. The crosstalk between Dectin1 and TLR4 via NF-κB subunits p65/RelB in mammary epithelial cells. Int Immunopharmacol. 2014;23:417-25 pubmed publisher
Wang Y, Zhang A, Lu S, Pan X, Jia D, Yu W, et al. Adenosine 5'-monophosphate-induced hypothermia inhibits the activation of ERK1/2, JNK, p38 and NF-κB in endotoxemic rats. Int Immunopharmacol. 2014;23:205-10 pubmed publisher
Dill McFarland K, Neil K, Zeng A, Sprenger R, Kurtz C, Suen G, et al. Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defence in the gut of 13-lined ground squirrels. Mol Ecol. 2014;23:4658-69 pubmed publisher
Sussman D, Santaolalla R, Bejarano P, Garcia Buitrago M, Perez M, Abreu M, et al. In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer. J Exp Clin Cancer Res. 2014;33:45 pubmed publisher
Wang Y, Weng Y, Shi Y, Xia X, Wang S, Duan H. Expression and functional analysis of Toll-like receptor 4 in human cervical carcinoma. J Membr Biol. 2014;247:591-9 pubmed publisher
Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, et al. The inflammasome pyrin contributes to pertussis toxin-induced IL-1? synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis. PLoS Pathog. 2014;10:e1004150 pubmed publisher
Green T, Santos M, Ejaeidi A, Craft B, Lewis R, Cruse J. Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells. Exp Mol Pathol. 2014;97:44-8 pubmed publisher
Schuster A, Klotz M, Schwab T, Di Liddo R, Bertalot T, Schrenk S, et al. Maintenance of the enteric stem cell niche by bacterial lipopolysaccharides? Evidence and perspectives. J Cell Mol Med. 2014;18:1429-43 pubmed publisher
Degraaf A, Zasłona Z, Bourdonnay E, Peters Golden M. Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation. Am J Respir Cell Mol Biol. 2014;51:242-50 pubmed publisher
Lacave Lapalun J, Benderitter M, Linard C. Flagellin and LPS each restores rat lymphocyte populations after colorectal irradiation. J Leukoc Biol. 2014;95:931-40 pubmed publisher
Raso G, Simeoli R, Iacono A, Santoro A, Amero P, Paciello O, et al. Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet. J Nutr Biochem. 2014;25:81-90 pubmed publisher
Kuhn H, Petzold K, Hammerschmidt S, Wirtz H. Interaction of cyclic mechanical stretch and toll-like receptor 4-mediated innate immunity in rat alveolar type II cells. Respirology. 2014;19:67-73 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
Semar S, Klotz M, Letiembre M, Van Ginneken C, Braun A, Jost V, et al. Changes of the enteric nervous system in amyloid-? protein precursor transgenic mice correlate with disease progression. J Alzheimers Dis. 2013;36:7-20 pubmed publisher
Ramani V, Madhusoodhanan R, Kosanke S, Awasthi S. A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation. Innate Immun. 2013;19:596-610 pubmed publisher
Tian J, Guo X, Liu X, Liu L, Weng Q, Dong S, et al. Extracellular HSP60 induces inflammation through activating and up-regulating TLRs in cardiomyocytes. Cardiovasc Res. 2013;98:391-401 pubmed publisher
Jazaeri F, Tavangar S, Ghazi Khansari M, Khorramizadeh M, Mani A, Dehpour A. Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats. Liver Int. 2013;33:368-74 pubmed publisher
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, et al. Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines. J Immunol. 2013;190:1859-72 pubmed publisher
McCulloch L, Brown K, Mabbott N. Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function. Immunology. 2013;138:246-57 pubmed publisher
Hsiao C, Kao Y, Huang S, Chuang J. Toll-like receptor-4 agonist inhibits motility and invasion of hepatoblastoma HepG2 cells in vitro. Pediatr Blood Cancer. 2013;60:248-53 pubmed publisher
Zheng Y, Yang M, Rong T, Yuan X, Ma Y, Wang Z, et al. CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer. World J Gastroenterol. 2012;18:2253-61 pubmed publisher
Liu Y, Fatheree N, Mangalat N, Rhoads J. Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-?B signaling in the intestine. Am J Physiol Gastrointest Liver Physiol. 2012;302:G608-17 pubmed publisher
Janardhanam S, Prakasam S, Swaminathan V, Kodumudi K, Zunt S, Srinivasan M. Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus. Arch Oral Biol. 2012;57:495-502 pubmed publisher
Weile C, Josefsen K, Buschard K. Glucose activation of islets of Langerhans up-regulates Toll-like receptor 5: possible mechanism of protection. Clin Exp Immunol. 2011;166:251-7 pubmed publisher
Voss E, Skuljec J, Gudi V, Skripuletz T, Pul R, Trebst C, et al. Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?. Neurobiol Dis. 2012;45:519-28 pubmed publisher
Sweeney T, Suliman H, Hollingsworth J, Welty Wolf K, Piantadosi C. A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis. PLoS ONE. 2011;6:e25249 pubmed publisher
Nowicki M, Kosacka J, Serke H, Bluher M, Spanel Borowski K. Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome. J Neurosci Res. 2012;90:122-31 pubmed publisher
Brandau S, Jakob M, Hemeda H, Bruderek K, Janeschik S, Bootz F, et al. Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge. J Leukoc Biol. 2010;88:1005-15 pubmed publisher
Hafez M, Hayes K, Goldrick M, Grencis R, Roberts I. The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in ep. Infect Immun. 2010;78:2153-62 pubmed publisher
Johnston M, Wang A, Catarino M, Ball L, Phan V, MacDonald J, et al. Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. Infect Immun. 2010;78:1364-75 pubmed publisher
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
Nowicki M, Muller K, Serke H, Kosacka J, Vilser C, Ricken A, et al. Oxidized low-density lipoprotein (oxLDL)-induced cell death in dorsal root ganglion cell cultures depends not on the lectin-like oxLDL receptor-1 but on the toll-like receptor-4. J Neurosci Res. 2010;88:403-12 pubmed publisher
Worku M, Morris A. Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils. J Dairy Sci. 2009;92:3185-93 pubmed publisher
O Hara S, Small A, Gajdos G, Badley A, Chen X, Larusso N. HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum. J Infect Dis. 2009;199:1195-204 pubmed publisher
Link A, Selejan S, Maack C, Lenz M, Bohm M. Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock. Crit Care. 2008;12:R159 pubmed publisher
Lunardi C, Bason C, Dolcino M, Navone R, Simone R, Saverino D, et al. Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease. J Intern Med. 2009;265:250-65 pubmed publisher
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
Yoshizaki A, Iwata Y, Komura K, Ogawa F, Hara T, Muroi E, et al. CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. Am J Pathol. 2008;172:1650-63 pubmed publisher
Kessel A, Toubi E, Pavlotzky E, Mogilner J, Coran A, Lurie M, et al. Treatment with glutamine is associated with down-regulation of Toll-like receptor-4 and myeloid differentiation factor 88 expression and decrease in intestinal mucosal injury caused by lipopolysaccharide endotoxaemia in a rat. Clin Exp Immunol. 2008;151:341-7 pubmed
Allam J, Peng W, Appel T, Wenghoefer M, Niederhagen B, Bieber T, et al. Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. J Allergy Clin Immunol. 2008;121:368-374.e1 pubmed
Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, et al. In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med. 2006;3:e358 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-6586
SKU :
NB120-6586
product name :
Collagen IV Antibody
description :
The Collagen IV Antibody from Novus Biologicals is a rabbit polyclonal antibody to Collagen IV. This antibody reacts with bovine,feline,human,mouse,rat. The Collagen IV Antibody has been validated for the following applications: Immunoprecipitation,Knockout Validated,IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Simple Western,Super-Resolution Microscopy,Immunocytochemistry/ Immunofluorescence.
target :
Collagen IV
unit size :
0.1 mg (also 0.02 mg)
category :
Primary Antibodies
buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Collagen IV from human and bovine placenta (Uniprot: P02462)
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Feline,Human,Mouse,Rat
specificity :
Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues
storage :
Store at 4C short term. For extended storage, add an equal volume of glycerol, aliquot and store at -20C or below. Avoid repeated freeze-thaw cycles.
gene symbol :
COL4A1
accessionNumbers :
P02462
applications :
Immunoprecipitation,Knockout Validated,IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Simple Western,Super-Resolution Microscopy,Immunocytochemistry/ Immunofluorescence
USD :
399
USD 2025 :
409 USD
alt names :
BSVD;BSVD1;COL4A1s;Collagen alpha-1(IV) chain;PADMAL;RATOR
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.