product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PABP Antibody (10E10) - BSA Free
catalog :
NB120-6125
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10E10
reactivity :
human, mouse, dogs, bovine
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human
Chazal P, Daguenet E, Wendling C, Ulryck N, Tomasetto C, Sargueil B, et al. EJC core component MLN51 interacts with eIF3 and activates translation. Proc Natl Acad Sci U S A. 2013;110:5903-8 pubmed publisher
  • western blot; mouse
Sagliocco F, Laloo B, Cosson B, Laborde L, Castroviejo M, Rosenbaum J, et al. The ARE-associated factor AUF1 binds poly(A) in vitro in competition with PABP. Biochem J. 2006;400:337-47 pubmed
  • western blot; human
Larralde O, Smith R, Wilkie G, Malik P, Gray N, Clements J. Direct stimulation of translation by the multifunctional herpesvirus ICP27 protein. J Virol. 2006;80:1588-91 pubmed
  • western blot; human
Nelson P, Hatzigeorgiou A, Mourelatos Z. miRNP:mRNA association in polyribosomes in a human neuronal cell line. RNA. 2004;10:387-94 pubmed
  • immunoprecipitation; human
Sladic R, Lagnado C, Bagley C, Goodall G. Human PABP binds AU-rich RNA via RNA-binding domains 3 and 4. Eur J Biochem. 2004;271:450-7 pubmed
  • immunoprecipitation; human
Lee J, Bedford M. PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays. EMBO Rep. 2002;3:268-73 pubmed
  • western blot; mouse
Grosset C, Chen C, Xu N, Sonenberg N, Jacquemin Sablon H, Shyu A. A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex. Cell. 2000;103:29-40 pubmed
Nagel M, Noss M, Xu J, Horn N, Ueffing M, Boldt K, et al. The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells. RNA. 2022;29:55-68 pubmed publisher
Shen T, Chen C, Tsai T, Jhan M, Bai C, Yen Y, et al. Hyperglycemia exacerbates dengue virus infection by facilitating poly(A)-binding protein-mediated viral translation. JCI Insight. 2022;7: pubmed publisher
Kim B, Park Y, Hwang H, Chang J, Kim Y, Lee J. Single polysome analysis of mRNP. Biochem Biophys Res Commun. 2022;618:73-78 pubmed publisher
Genois M, Gagné J, Yasuhara T, Jackson J, Saxena S, Langelier M, et al. CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2021;81:784-800.e8 pubmed publisher
Pelagalli A, Nardelli A, Lucarelli E, Zannetti A, Brunetti A. Autocrine signals increase ovine mesenchymal stem cells migration through Aquaporin-1 and CXCR4 overexpression. J Cell Physiol. 2018;233:6241-6249 pubmed publisher
Irie Y, Tsubota M, Ishikura H, Sekiguchi F, Terada Y, Tsujiuchi T, et al. Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis. J Neuroimmune Pharmacol. 2017;12:693-707 pubmed publisher
Gagner J, Sarfraz Y, Ortenzi V, Alotaibi F, Chiriboga L, Tayyib A, et al. Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination. Am J Pathol. 2017;187:2080-2094 pubmed publisher
Dieckow J, Brandt W, Hattermann K, Schob S, Schulze U, Mentlein R, et al. CXCR4 and CXCR7 Mediate TFF3-Induced Cell Migration Independently From the ERK1/2 Signaling Pathway. Invest Ophthalmol Vis Sci. 2016;57:56-65 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-6125
SKU :
NB120-6125
product name :
PABP Antibody (10E10) - BSA Free
description :
The PABP Antibody (10E10) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to PABP. This antibody reacts with bovine,canine,drosophila (negative),human,mouse,mouse (negative),primate,xenopus. The PABP Antibody (10E10) - BSA Free has been validated for the following applications: Flow Cytometry,ELISA,Microarray,CyTOF-ready,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation,Western Blot.
target :
PABP
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
10E10
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human PABP protein. [Uniprot# P11940]
isotype :
IgG2b
purity :
Protein G purified
species :
Bovine,Canine,Drosophila (Negative),Human,Mouse,Mouse (Negative),Primate,Xenopus
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
69 kDa
gene symbol :
PABPC1
accessionNumbers :
P11940
applications :
Flow Cytometry,ELISA,Microarray,CyTOF-ready,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation,Western Blot
USD :
399
USD 2025 :
409 USD
alt names :
PAB1polyadenylate-binding protein 1, PABP, PABP-1, PABP1poly(A) binding protein, cytoplasmic 2, PABPC2, PABPL1, poly(A) binding protein, cytoplasmic 1, Poly(A)-binding protein 1, poly(A)-binding protein, cytoplasmic 2
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.