JAB1 Antibody (2A10.8) | Novus Biologicals NB120-495 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

JAB1 Antibody (2A10.8)

catalog :

NB120-495

quantity :

100 ul

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A10.8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 13

Reference
Schiffmacher D, Lee S, Kliza K, Theil A, Akita M, Helfricht A, et al. DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II. Res Sq. 2023;: pubmed publisher
Israel S, Drexler H, Fuellen G, Boiani M. The COP9 signalosome subunit 3 is necessary for early embryo survival by way of a stable protein deposit in mouse oocytes. Mol Hum Reprod. 2021;27: pubmed publisher
Karpiyevich M, Adjalley S, Mol M, Ascher D, Mason B, van der Heden van Noort G, et al. Nedd8 hydrolysis by UCH proteases in Plasmodium parasites. PLoS Pathog. 2019;15:e1008086 pubmed publisher
Jenvey C, Shircliff A, Bannantine J, Stabel J. Phenotypes of macrophages present in the intestine are impacted by stage of disease in cattle naturally infected with Mycobacterium avium subsp. paratuberculosis. PLoS ONE. 2019;14:e0217649 pubmed publisher
Wang R, Wang H, Carrera I, Xu S, Lakshmana M. COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain. J Biol Chem. 2015;290:9299-309 pubmed publisher
Wang H, Dey D, Carrera I, Minond D, Bianchi E, Xu S, et al. COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels. J Biol Chem. 2013;288:26668-77 pubmed publisher
Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, et al. The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proc Natl Acad Sci U S A. 2011;108:E577-85 pubmed publisher
Marquet F, Bonneau M, Pascale F, Urien C, Kang C, Schwartz Cornil I, et al. Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model. PLoS ONE. 2011;6:e16320 pubmed publisher
McCall C, Miliani de Marval P, Chastain P, Jackson S, He Y, Kotake Y, et al. Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Mol Cell Biol. 2008;28:5621-33 pubmed publisher
Yun J, Tomida A, Andoh T, Tsuruo T. Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5. J Biol Chem. 2004;279:31296-303 pubmed
Doronkin S, Djagaeva I, Beckendorf S. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development. 2002;129:5053-64 pubmed
Korbonits M, Chahal H, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, et al. Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J Clin Endocrinol Metab. 2002;87:2635-43 pubmed
Gemmill R, Bemis L, Lee J, Sozen M, Baron A, Zeng C, et al. The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway. Oncogene. 2002;21:3507-16 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB120-495

SKU :

NB120-495

product name :

JAB1 Antibody (2A10.8)

description :

The JAB1 Antibody (2A10.8) from Novus Biologicals is a mouse monoclonal antibody to JAB1. This antibody reacts with drosophila,human,mouse,rat. The JAB1 Antibody (2A10.8) has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence.

target :

JAB1

unit size :

100 ul

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

2A10.8

conjugate :

Unconjugated

host :

Mouse

immunogen :

The full-length mouse JAB-1 gene expressed in E. coli.

isotype :

IgG2b

purity :

Protein G purified

species :

Drosophila,Human,Mouse,Rat

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

theoretical molecular weight :

38 kDa

gene symbol :

COPS5

accessionNumbers :

Q92905

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence

USD :

449

USD 2025 :

459 USD

alt names :

COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), COP9 signalosome complex subunit 5, CSN5COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5, EC 3.4, JAB138 kDa Mov34 homolog, Jun activation domain-binding protein 1, MOV-34, SGN5MGC3149, Signalosome subunit 5

more info or order :

Novus Biologicals product webpage