NFAT5 Antibody | Novus Biologicals NB120-3446 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NFAT5 Antibody

catalog :

NB120-3446

quantity :

50 ug (also 25 ug)

price :

419 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 8c	Liu C, Choi H, Johnson Z, Tian J, Shapiro I, Risbud M. Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus. Sci Rep. 2017;7:4543 pubmed publisher
	Laban H, Siegmund S, Zappe M, Trogisch F, Heineke J, Torre C, et al. NFAT5/TonEBP Limits Pulmonary Vascular Resistance in the Hypoxic Lung by Controlling Mitochondrial Reactive Oxygen Species Generation in Arterial Smooth Muscle Cells. Cells. 2021;10: pubmed publisher
	Kappert L, Ruzicka P, Kutikhin A, de la Torre C, Fischer A, Hecker M, et al. Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells. FASEB J. 2021;35:e21831 pubmed publisher
	Martínez Høyer S, Deng Y, Parker J, Jiang J, Mo A, Docking T, et al. Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome. Nat Cell Biol. 2020;22:526-533 pubmed publisher
	Pelzl L, Sahu I, Ma K, Heinzmann D, Bhuyan A, Al Maghout T, et al. Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes. Sci Rep. 2020;10:1728 pubmed publisher
	Choi H, Madhu V, Shapiro I, Risbud M. Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation. Sci Rep. 2019;9:15469 pubmed publisher
	de Wispelaere M, Du G, Donovan K, Zhang T, Eleuteri N, Yuan J, et al. Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nat Commun. 2019;10:3468 pubmed publisher
	Chen L, Cao J, Cao D, Wang M, Xiang H, Yang Y, et al. Protective effect of dexmedetomidine against diabetic hyperglycemia-exacerbated cerebral ischemia/reperfusion injury: An in vivo and in vitro study. Life Sci. 2019;:116553 pubmed publisher
	Rasmussen R, Christensen K, Holm R, Nielsen C. Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells. FEBS Open Bio. 2019;9:1071-1081 pubmed publisher
	Girardini M, Maniaci C, Hughes S, Testa A, Ciulli A. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019;27:2466-2479 pubmed publisher
	Zoppi V, Hughes S, Maniaci C, Testa A, Gmaschitz T, Wieshofer C, et al. Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of BRD9 and BRD7. J Med Chem. 2018;: pubmed publisher
	Donovan K, An J, Nowak R, Yuan J, Fink E, Berry B, et al. Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. elife. 2018;7: pubmed publisher
	Choi H, Chaiyamongkol W, Doolittle A, Johnson Z, Gogate S, Schoepflin Z, et al. COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells. J Biol Chem. 2018;293:8969-8981 pubmed publisher
	Olson C, Jiang B, Erb M, Liang Y, Doctor Z, Zhang Z, et al. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nat Chem Biol. 2017;: pubmed publisher
	Huang H, Dobrovolsky D, Paulk J, Yang G, Weisberg E, Doctor Z, et al. A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader. Cell Chem Biol. 2018;25:88-99.e6 pubmed publisher
	An J, Ponthier C, Sack R, Seebacher J, Stadler M, Donovan K, et al. pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase. Nat Commun. 2017;8:15398 pubmed publisher
	Hollborn M, Fischer S, Kuhrt H, Wiedemann P, Bringmann A, Kohen L. Osmotic regulation of NFAT5 expression in RPE cells: The involvement of purinergic receptor signaling. Mol Vis. 2017;23:116-130 pubmed
	Johnson Z, Shapiro I, Risbud M. RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?. J Biol Chem. 2016;291:26686-26697 pubmed publisher

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB120-3446

SKU :

NB120-3446

product name :

NFAT5 Antibody

description :

The NFAT5 Antibody from Novus Biologicals is a rabbit polyclonal antibody to NFAT5. This antibody reacts with canine,hamster,human,mouse,rabbit,rat. The NFAT5 Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),IF/IHC,Western Blot,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.

target :

NFAT5

unit size :

50 ug (also 25 ug)

category :

Primary Antibodies

buffer :

PBS with 1 mg/ml BSA

clonality :

Polyclonal

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide corresponding to residues C D(1439) L L V S L Q N Q G N N L T G S F(1455) of human NFAT5.

isotype :

IgG

purity :

Immunogen affinity purified

species :

Canine,Hamster,Human,Mouse,Rabbit,Rat

storage :

Store at -20C. Avoid freeze-thaw cycles.

gene symbol :

NFAT5

Antibody validation :

Biological Validation

accessionNumbers :

O94916

applications :

Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Gel Super Shift Assays,Chromatin Immunoprecipitation (ChIP),IF/IHC,Western Blot,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

419 USD

alt names :

EC 3.6.1, EC 3.6.3.14, KIAA0827glutamine rich protein H65, NF-AT5NFAT-like protein 1, NFATL1, NFATZ, nuclear factor of activated T-cells 5, tonicity-responsive, OREBP, osmotic response element-binding protein, T-cell transcription factor NFAT5, TonE-binding protein, TonEBP, TONEBPnuclear factor of activated T-cells 5, Tonicity-responsive enhancer-binding protein

more info or order :

Novus Biologicals product webpage