MUC1 Antibody (SM3) - BSA Free | Novus Biologicals NB120-22711 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MUC1 Antibody (SM3) - BSA Free

catalog :

NB120-22711

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SM3

reactivity :

human, mouse

application :

ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Sørensen A, Reis C, Tarp M, Mandel U, Ramachandran K, Sankaranarayanan V, et al. Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycobiology. 2006;16:96-107 pubmed
flow cytometry; human	Dalziel M, Whitehouse C, McFarlane I, Brockhausen I, Gschmeissner S, Schwientek T, et al. The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1. J Biol Chem. 2001;276:11007-15 pubmed
immunohistochemistry; human	Mommers E, Leonhart A, von Mensdorff Pouilly S, Schol D, Hilgers J, Meijer C, et al. Aberrant expression of MUC1 mucin in ductal hyperplasia and ductal carcinoma In situ of the breast. Int J Cancer. 1999;84:466-9 pubmed
flow cytometry; human	Henderikx P, Kandilogiannaki M, Petrarca C, von Mensdorff Pouilly S, Hilgers J, Krambovitis E, et al. Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma. Cancer Res. 1998;58:4324-32 pubmed
ELISA; human	Karsten U, Diotel C, Klich G, Paulsen H, Goletz S, Muller S, et al. Enhanced binding of antibodies to the DTR motif of MUC1 tandem repeat peptide is mediated by site-specific glycosylation. Cancer Res. 1998;58:2541-9 pubmed
flow cytometry; human	Bohm C, Mulder M, Zennadi R, Notter M, Schmitt Gräff A, Finn O, et al. Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation. Scand J Immunol. 1997;46:27-34 pubmed
ELISA; human	Hanisch F, Stadie T, Deutzmann F, Peter Katalinic J. MUC1 glycoforms in breast cancer--cell line T47D as a model for carcinoma-associated alterations of 0-glycosylation. Eur J Biochem. 1996;236:318-27 pubmed
ELISA; human	Ho J, Siddiki B, Kim Y. Association of sialyl-Lewis(a) and sialyl-Lewis(x) with MUC-1 apomucin ina pancreatic cancer cell line. Cancer Res. 1995;55:3659-63 pubmed
flow cytometry; human	Brockhausen I, Yang J, Burchell J, Whitehouse C, Taylor Papadimitriou J. Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells. Eur J Biochem. 1995;233:607-17 pubmed
immunohistochemistry; human	Kotera Y, Fontenot J, Pecher G, Metzgar R, Finn O. Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients. Cancer Res. 1994;54:2856-60 pubmed
immunohistochemistry; human immunohistochemistry; mouse	Peat N, Gendler S, Lalani N, Duhig T, Taylor Papadimitriou J. Tissue-specific expression of a human polymorphic epithelial mucin (MUC1) in transgenic mice. Cancer Res. 1992;52:1954-60 pubmed
	Lucarelli G, Netti G, Rutigliano M, Lasorsa F, Loizzo D, Milella M, et al. MUC1 Expression Affects the Immunoflogosis in Renal Cell Carcinoma Microenvironment through Complement System Activation and Immune Infiltrate Modulation. Int J Mol Sci. 2023;24: pubmed publisher
	Nalawade S, Shafer P, Bajgain P, McKenna M, Ali A, Kelly L, et al. Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer. J Immunother Cancer. 2021;9: pubmed publisher
	Wu K, Tang F, Lee D, Zhao Y, Song H, Zhu X, et al. Ependymal Vps35 Promotes Ependymal Cell Differentiation and Survival, Suppresses Microglial Activation, and Prevents Neonatal Hydrocephalus. J Neurosci. 2020;40:3862-3879 pubmed publisher
	Cougnoux A, Drummond R, Fellmeth M, Navid F, Collar A, Iben J, et al. Unique molecular signature in mucolipidosis type IV microglia. J Neuroinflammation. 2019;16:276 pubmed publisher
	Cougnoux A, Fellmeth M, Gu T, Davidson C, Gibson A, Pavan W, et al. Maternal immune activation modifies the course of Niemann-pick disease, type C1 in a gender specific manner. Mol Genet Metab. 2020;129:165-170 pubmed publisher
	Zhang Y, Zhang Y, Wu R, Gao F, Zang P, Hu X, et al. Effect of cerebral small vessel disease on cognitive function and TLR4 expression in hippocampus. J Clin Neurosci. 2019;67:210-214 pubmed publisher
	Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed publisher
	Ha S, Jeong S, Yi K, Chu J, Kim S, Kim E, et al. Autophagy Mediates Astrogenesis in Adult Hippocampal Neural Stem Cells. Exp Neurobiol. 2019;28:229-246 pubmed publisher
	McWilliams I, Kielczewski J, Ireland D, Sykes J, Lewkowicz A, Konduru K, et al. Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice. Cell Rep. 2019;26:1718-1726.e4 pubmed publisher
	Dhekne H, Yanatori I, Gomez R, Tonelli F, Diez F, Schule B, et al. A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. elife. 2018;7: pubmed publisher
	Cougnoux A, Clifford S, Salman A, Ng S, Bertin J, Porter F. Necroptosis inhibition as a therapy for Niemann-Pick disease, type C1: Inhibition of RIP kinases and combination therapy with 2-hydroxypropyl-β-cyclodextrin. Mol Genet Metab. 2018;125:345-350 pubmed publisher
	Gaire J, Lee H, Hilborn N, Ward R, Regan M, Otto K. The role of inflammation on the functionality of intracortical microelectrodes. J Neural Eng. 2018;15:066027 pubmed publisher
	Anderson M, O Shea T, Burda J, Ao Y, Barlatey S, Bernstein A, et al. Required growth facilitators propel axon regeneration across complete spinal cord injury. Nature. 2018;561:396-400 pubmed publisher
	Kumar N, Lochhead J, Pizzo M, Nehra G, Boroumand S, Greene G, et al. Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery. J Control Release. 2018;286:467-484 pubmed publisher
	Chavez Valdez R, Emerson P, Goffigan Holmes J, Kirkwood A, Martin L, Northington F. Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model. Hippocampus. 2018;28:617-630 pubmed publisher

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB120-22711

SKU :

NB120-22711

product name :

MUC1 Antibody (SM3) - BSA Free

description :

The MUC1 Antibody (SM3) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to MUC1. This antibody reacts with human,mouse. The MUC1 Antibody (SM3) - BSA Free has been validated for the following applications: Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,ELISA,Immunohistochemistry.

target :

MUC1

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

SM3

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Hydrogen fluoride deglycosylated milk mucin.

isotype :

IgG2a Kappa

purity :

Protein G purified

species :

Human,Mouse

specificity :

Reacts very little with normal tissue

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

gene symbol :

MUC1

accessionNumbers :

P15941

applications :

Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,ELISA,Immunohistochemistry

USD :

399

USD 2025 :

409 USD

alt names :

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

more info or order :

Novus Biologicals product webpage