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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Calcium-sensing R/CaSR Antibody (5C10, ADD) - BSA Free
catalog :
NB120-19347
quantity :
0.1 mg (also 0.025 mg)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C10, ADD
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 82
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 2 ug/ml; fig 1a
Koh J, Hogue J, Sosa J. A Novel Ex Vivo Method for Visualizing Live-Cell Calcium Response Behavior in Intact Human Tumors. PLoS ONE. 2016;11:e0161134 pubmed publisher
Sherman B, Calderon E, Price R. Characterizing the Role of Calcium Sensing Receptor in the Progression of Obesity-Mediated Aggressive Prostate Cancer Phenotype. Nutr Cancer. 2023;75:960-970 pubmed publisher
. Impaired kidney structure and function in spinal muscular atrophy. Neurol Genet. 2019;5:e353 pubmed publisher
Ishiguro N, Moriyama M, Furusho K, Furukawa S, Shibata T, Murakami Y, et al. Activated M2 macrophage contributes to the pathogenesis of IgG4-related disease via TLR7/IL-33 signaling. Arthritis Rheumatol. 2019;: pubmed publisher
Bächinger D, Egli H, Goosmann M, Monge Naldi A, Eckhard A. Immunolocalization of calcium sensing and transport proteins in the murine endolymphatic sac indicates calciostatic functions within the inner ear. Cell Tissue Res. 2019;378:163-173 pubmed publisher
Olde Heuvel F, Holl S, Chandrasekar A, Li Z, Wang Y, Rehman R, et al. STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI. Brain Behav Immun. 2019;: pubmed publisher
Luchsinger L, Strikoudis A, Danzl N, Bush E, Finlayson M, Satwani P, et al. Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro. Cell Stem Cell. 2019;: pubmed publisher
Issa H, Hénaut L, Abdallah J, Boudot C, Lenglet G, Avondo C, et al. Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification. J Mol Cell Cardiol. 2019;129:2-12 pubmed publisher
Sayour E, Grippin A, De Leon G, Stover B, Rahman M, Karachi A, et al. Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy. Nano Lett. 2018;18:6195-6206 pubmed publisher
Frees S, Breuksch I, Haber T, Bauer H, Chavez Munoz C, Raven P, et al. Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma. Oncotarget. 2018;9:15766-15779 pubmed publisher
Boudot C, Hénaut L, Thiem U, Geraci S, Galante M, Saldanha P, et al. Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation. Oncotarget. 2017;8:56460-56472 pubmed publisher
Kostarnoy A, Gancheva P, Lepenies B, Tukhvatulin A, Dzharullaeva A, Polyakov N, et al. Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate. Proc Natl Acad Sci U S A. 2017;114:E2758-E2765 pubmed publisher
Dai X, Perez P, Soria G, Scarinci N, Smoler M, Morsucci D, et al. External Ca2+ regulates polycystin-2 (TRPP2) cation currents in LLC-PK1 renal epithelial cells. Exp Cell Res. 2017;350:50-61 pubmed publisher
Chalise J, Pallotta M, Narendra S, Carlsson B, Iacono A, Namale J, et al. IDO1 and TGF-? Mediate Protective Effects of IFN-? in Antigen-Induced Arthritis. J Immunol. 2016;197:3142-3151 pubmed
Pan Z, Horton C, Lawrence C, Farris A. Plasmacytoid dendritic cells and type 1 interferon promote peripheral expansion of forkhead box protein 3(+) regulatory T cells specific for the ubiquitous RNA-binding nuclear antigen La/Sjögren's syndrome (SS)-B. Clin Exp Immunol. 2016;186:18-29 pubmed publisher
Koh J, Hogue J, Wang Y, DiSalvo M, Allbritton N, Shi Y, et al. Single-cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism. J Cell Mol Med. 2016;20:351-9 pubmed publisher
Londrigan S, Tate M, Job E, Moffat J, Wakim L, Gonelli C, et al. Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection. PLoS ONE. 2015;10:e0142925 pubmed publisher
Givi M, Akbari P, Boon L, Puzovic V, Bezemer G, Ricciardolo F, et al. Dendritic cells inversely regulate airway inflammation in cigarette smoke-exposed mice. Am J Physiol Lung Cell Mol Physiol. 2016;310:L95-102 pubmed publisher
Arai Y, Yamashita K, Kuriyama K, Shiokawa M, Kodama Y, Sakurai T, et al. Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis. J Immunol. 2015;195:3033-44 pubmed publisher
Shilo V, Ben Dov I, Nechama M, Silver J, Naveh Many T. Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia. FASEB J. 2015;29:3964-76 pubmed publisher
Cocita C, Guiton R, Bessou G, Chasson L, Boyron M, Crozat K, et al. Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus. PLoS Pathog. 2015;11:e1004897 pubmed publisher
Biswas M, Sarkar D, Kumar S, Nayak S, Rogers G, Markusic D, et al. Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg. Blood. 2015;125:2937-47 pubmed publisher
Scheffler J, Sparber F, Tripp C, Herrmann C, Humenberger A, Blitz J, et al. LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling. Nat Commun. 2014;5:5138 pubmed publisher
Biessen E, Christ A. Plasmacytoid dendritic cells in atherosclerosis: knocking at T-cell's door. Circulation. 2014;130:1340-2 pubmed publisher
Szalat A, Shahar M, Shpitzen S, Nachmias B, Munter G, Gillis D, et al. Calcium-sensing receptor sequencing in 21 patients with idiopathic or familial parathyroid disorder: pitfalls and characterization of a novel I32 V loss-of-function mutation. Endocrine. 2015;48:444-53 pubmed publisher
Cao W. Pivotal Functions of Plasmacytoid Dendritic Cells in Systemic Autoimmune Pathogenesis. J Clin Cell Immunol. 2014;5:212 pubmed
Guo L, Yan D, Yang D, Li Y, Wang X, Zalewski O, et al. Combinatorial photothermal and immuno cancer therapy using chitosan-coated hollow copper sulfide nanoparticles. ACS Nano. 2014;8:5670-81 pubmed publisher
Haque A, Best S, Montes De Oca M, James K, Ammerdorffer A, Edwards C, et al. Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest. 2014;124:2483-96 pubmed publisher
Jiao J, Dragomir A, Kocabayoglu P, Rahman A, Chow A, Hashimoto D, et al. Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils. J Immunol. 2014;192:3374-82 pubmed publisher
Yokogawa M, Takaishi M, Nakajima K, Kamijima R, Fujimoto C, Kataoka S, et al. Epicutaneous application of toll-like receptor 7 agonists leads to systemic autoimmunity in wild-type mice: a new model of systemic Lupus erythematosus. Arthritis Rheumatol. 2014;66:694-706 pubmed publisher
Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, et al. Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion. PLoS Genet. 2013;9:e1003975 pubmed publisher
Narendra S, Chalise J, Höök N, Magnusson M. Dendritic cells activated by double-stranded RNA induce arthritis via autocrine type I IFN signaling. J Leukoc Biol. 2014;95:661-6 pubmed publisher
Hackstein H, Kranz S, Lippitsch A, Wachtendorf A, Kershaw O, Gruber A, et al. Modulation of respiratory dendritic cells during Klebsiella pneumonia infection. Respir Res. 2013;14:91 pubmed publisher
Willart M, Poulliot P, Lambrecht B, Kool M. PAMPs and DAMPs in allergy exacerbation models. Methods Mol Biol. 2013;1032:185-204 pubmed publisher
Le Mercier I, Poujol D, Sanlaville A, Sisirak V, Gobert M, Durand I, et al. Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatment. Cancer Res. 2013;73:4629-40 pubmed publisher
Walter S, Baruch A, Dong J, Tomlinson J, Alexander S, Janes J, et al. Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients. J Pharmacol Exp Ther. 2013;346:229-40 pubmed publisher
Budimir N, de Haan A, Meijerhof T, Waijer S, Boon L, Gostick E, et al. Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine. PLoS ONE. 2013;8:e63163 pubmed publisher
Ioannou M, Alissafi T, Boon L, Boumpas D, Verginis P. In vivo ablation of plasmacytoid dendritic cells inhibits autoimmunity through expansion of myeloid-derived suppressor cells. J Immunol. 2013;190:2631-40 pubmed publisher
Tahiliani V, Chaudhri G, Eldi P, Karupiah G. The orchestrated functions of innate leukocytes and T cell subsets contribute to humoral immunity, virus control, and recovery from secondary poxvirus challenge. J Virol. 2013;87:3852-61 pubmed publisher
Moffat J, Segura E, Khoury G, Caminschi I, Cameron P, Lewin S, et al. Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation. Eur J Immunol. 2013;43:595-605 pubmed publisher
Crother T, Ma J, Jupelli M, Chiba N, Chen S, Slepenkin A, et al. Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice. PLoS ONE. 2012;7:e48655 pubmed publisher
Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012;13:94 pubmed publisher
Sathe P, Vremec D, Wu L, Corcoran L, Shortman K. Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells. Blood. 2013;121:11-9 pubmed publisher
Toka H, Al Romaih K, Koshy J, Dibartolo S, Kos C, Quinn S, et al. Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol. 2012;23:1879-90 pubmed publisher
Weigert A, Weichand B, Sekar D, Sha W, Hahn C, Mora J, et al. HIF-1? is a negative regulator of plasmacytoid DC development in vitro and in vivo. Blood. 2012;120:3001-6 pubmed publisher
Pinto A, Rega A, Crother T, Sorrentino R. Plasmacytoid dendritic cells and their therapeutic activity in cancer. Oncoimmunology. 2012;1:726-734 pubmed
Cheong C, Choi J. Dendritic cells and regulatory T cells in atherosclerosis. Mol Cells. 2012;34:341-7 pubmed publisher
Umemoto E, Otani K, Ikeno T, Verjan Garcia N, Hayasaka H, Bai Z, et al. Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling. J Immunol. 2012;189:191-9 pubmed publisher
Schlitzer A, Heiseke A, Einwächter H, Reindl W, Schiemann M, Manta C, et al. Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor. Blood. 2012;119:6063-71 pubmed publisher
Alari Pahissa E, Vega Ramos J, Zhang J, Castaño A, Turley S, Villadangos J, et al. Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation. J Leukoc Biol. 2012;92:145-58 pubmed publisher
Soloff A, Weirback H, Ross T, Barratt Boyes S. Plasmacytoid dendritic cell depletion leads to an enhanced mononuclear phagocyte response in lungs of mice with lethal influenza virus infection. Comp Immunol Microbiol Infect Dis. 2012;35:309-17 pubmed publisher
Markey K, Koyama M, Kuns R, Lineburg K, Wilson Y, Olver S, et al. Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood. 2012;119:5918-30 pubmed publisher
Daissormont I, Christ A, Temmerman L, Sampedro Millares S, Seijkens T, Manca M, et al. Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity. Circ Res. 2011;109:1387-95 pubmed publisher
Nierkens S, den Brok M, Garcia Z, Togher S, Wagenaars J, Wassink M, et al. Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells. Cancer Res. 2011;71:6428-37 pubmed publisher
Wykes M, Kay J, Manderson A, Liu X, Brown D, Richard D, et al. Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proc Natl Acad Sci U S A. 2011;108:11205-10 pubmed publisher
Lahoud M, Ahmet F, Kitsoulis S, Wan S, Vremec D, Lee C, et al. Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J Immunol. 2011;187:842-50 pubmed publisher
Diana J, Brezar V, Beaudoin L, Dalod M, Mellor A, Tafuri A, et al. Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay. J Exp Med. 2011;208:729-45 pubmed publisher
Rochereau N, Verrier B, Pin J, Genin C, Paul S. Phenotypic localization of distinct DC subsets in mouse Peyer Patch. Vaccine. 2011;29:3655-61 pubmed publisher
Liu X, Mishra P, Yu S, Beckmann J, Wendland M, Kocks J, et al. Tolerance induction towards cardiac allografts under costimulation blockade is impaired in CCR7-deficient animals but can be restored by adoptive transfer of syngeneic plasmacytoid dendritic cells. Eur J Immunol. 2011;41:611-23 pubmed publisher
Seth S, Oberdörfer L, Hyde R, Hoff K, Thies V, Worbs T, et al. CCR7 essentially contributes to the homing of plasmacytoid dendritic cells to lymph nodes under steady-state as well as inflammatory conditions. J Immunol. 2011;186:3364-72 pubmed publisher
Lau Kilby A, Kretz C, Pechhold S, Price J, Dorta S, Ramos H, et al. Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells. Proc Natl Acad Sci U S A. 2011;108:2408-13 pubmed publisher
Galitzer H, Ben Dov I, Silver J, Naveh Many T. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int. 2010;77:211-8 pubmed publisher
Mascarell L, Lombardi V, Zimmer A, Louise A, Tourdot S, Van Overtvelt L, et al. Mapping of the lingual immune system reveals the presence of both regulatory and effector CD4+ T cells. Clin Exp Allergy. 2009;39:1910-9 pubmed publisher
Meir T, Levi R, Lieben L, Libutti S, Carmeliet G, Bouillon R, et al. Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology. Am J Physiol Renal Physiol. 2009;297:F1192-8 pubmed publisher
Seeds R, Gordon S, Miller J. Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery. J Immunol Methods. 2009;350:106-17 pubmed publisher
Jongbloed S, Benson R, Nickdel M, Garside P, McInnes I, Brewer J. Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. J Immunol. 2009;182:963-8 pubmed
Alam M, Kirton J, Wilkinson F, Towers E, Sinha S, Rouhi M, et al. Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovasc Res. 2009;81:260-8 pubmed publisher
Goubier A, Dubois B, Gheit H, Joubert G, Villard Truc F, Asselin Paturel C, et al. Plasmacytoid dendritic cells mediate oral tolerance. Immunity. 2008;29:464-75 pubmed publisher
Mascarell L, Lombardi V, Louise A, Saint Lu N, Chabre H, Moussu H, et al. Oral dendritic cells mediate antigen-specific tolerance by stimulating TH1 and regulatory CD4+ T cells. J Allergy Clin Immunol. 2008;122:603-9.e5 pubmed publisher
GeurtsvanKessel C, Willart M, van Rijt L, Muskens F, Kool M, Baas C, et al. Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells. J Exp Med. 2008;205:1621-34 pubmed publisher
Massberg S, Schaerli P, Knezevic Maramica I, Köllnberger M, Tubo N, Moseman E, et al. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell. 2007;131:994-1008 pubmed
Zucchini N, Bessou G, Robbins S, Chasson L, Raper A, Crocker P, et al. Individual plasmacytoid dendritic cells are major contributors to the production of multiple innate cytokines in an organ-specific manner during viral infection. Int Immunol. 2008;20:45-56 pubmed
Wendland M, Czeloth N, Mach N, Malissen B, Kremmer E, Pabst O, et al. CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine. Proc Natl Acad Sci U S A. 2007;104:6347-52 pubmed
Blasius A, Giurisato E, Cella M, Schreiber R, Shaw A, Colonna M. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol. 2006;177:3260-5 pubmed
Sjölin H, Robbins S, Bessou G, Hidmark A, Tomasello E, Johansson M, et al. DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection. J Immunol. 2006;177:2908-16 pubmed
Allman D, Dalod M, Asselin Paturel C, Delale T, Robbins S, Trinchieri G, et al. Ikaros is required for plasmacytoid dendritic cell differentiation. Blood. 2006;108:4025-34 pubmed
Delale T, Paquin A, Asselin Paturel C, Dalod M, Brizard G, Bates E, et al. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol. 2005;175:6723-32 pubmed
Mellor A, Baban B, Chandler P, Manlapat A, Kahler D, Munn D. Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling. J Immunol. 2005;175:5601-5 pubmed
Weston A, Absi M, Ward D, Ohanian J, Dodd R, Dauban P, et al. Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231. Circ Res. 2005;97:391-8 pubmed
Fallarino F, Asselin Paturel C, Vacca C, Bianchi R, Gizzi S, Fioretti M, et al. Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement. J Immunol. 2004;173:3748-54 pubmed
Asselin Paturel C, Brizard G, Pin J, Briere F, Trinchieri G. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J Immunol. 2003;171:6466-77 pubmed
Goldsmith P, Fan G, Ray K, Shiloach J, McPhie P, Rogers K, et al. Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor. J Biol Chem. 1999;274:11303-9 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-19347
SKU :
NB120-19347
product name :
Calcium-sensing R/CaSR Antibody (5C10, ADD) - BSA Free
description :
The Calcium-sensing R/CaSR Antibody (5C10, ADD) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to Calcium-sensing R/CaSR. This antibody reacts with bovine,human,mouse,porcine,rat. The Calcium-sensing R/CaSR Antibody (5C10, ADD) - BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Flow Cytometry,ELISA,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.
target :
Calcium-sensing R/CaSR
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
5C10, ADD
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Partial synthetic peptide corresponding to residues 214 - 235 of human calcium sensing receptor R/ CaSR [UniProt P41180]
isotype :
IgG2a
purity :
Protein A or G purified
species :
Bovine,Human,Mouse,Porcine,Rat
storage :
Store at -20C. Avoid freeze-thaw cycles.
gene symbol :
CASR
accessionNumbers :
P41180
applications :
Immunohistochemistry,IF/IHC,Flow Cytometry,ELISA,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
459 USD
alt names :
calcium-sensing receptor, CAR, CaSR, EIG8, extracellular calcium-sensing receptor, FHH, FIH, GPRC2AHHC, HHC1, hypocalciuric hypercalcemia 1, NSHPT, parathyroid Ca(2+)-sensing receptor 1, Parathyroid cell calcium-sensing receptor, PCaR1, PCAR1MGC138441
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.