product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD133 Antibody - BSA Free
catalog :
NB120-16518
quantity :
0.1 mg (also 0.025 mg)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
19D759.2
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 67
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:50; loading ...
Pham Q, Taniyama D, Sekino Y, Akabane S, Babasaki T, Kobayashi G, et al. Clinicopathologic features of TDO2 overexpression in renal cell carcinoma. BMC Cancer. 2021;21:737 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6c
Wang P, Zhao L, Gong S, Xiong S, Wang J, Zou D, et al. HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia. Cell Death Dis. 2021;12:312 pubmed publisher
  • immunoprecipitation; human; 1:2000; fig 1
Wang J, Liu X, Jiang Z, Li L, Cui Z, Gao Y, et al. A novel method to limit breast cancer stem cells in states of quiescence, proliferation or differentiation: Use of gel stress in combination with stem cell growth factors. Oncol Lett. 2016;12:1355-1360 pubmed
  • immunohistochemistry; mouse; loading ...; fig s1b
Lubeseder Martellato C, Hidalgo Sastre A, Hartmann C, Alexandrow K, Kamyabi Moghaddam Z, Sipos B, et al. Membranous CD24 drives the epithelial phenotype of pancreatic cancer. Oncotarget. 2016;7:49156-49168 pubmed publisher
Iqbal F, Johnston A, Wyse B, Rabani R, Mander P, Hoseini B, et al. Combination human umbilical cord perivascular and endothelial colony forming cell therapy for ischemic cardiac injury. NPJ Regen Med. 2023;8:45 pubmed publisher
Saha D, Mitra D, Alam N, Sen S, Mustafi S, Majumder P, et al. Lupeol and Paclitaxel cooperate in hindering hypoxia induced vasculogenic mimicry via suppression of HIF-1α-EphA2-Laminin-5γ2 network in human oral cancer. J Cell Commun Signal. 2023;17:591-608 pubmed publisher
Zhou L, Yang T, Zhao F, Song K, Xu L, Xu Z, et al. Effect of uncultured adipose-derived stromal vascular fraction on preventing urethral stricture formation in rats. Sci Rep. 2022;12:3573 pubmed publisher
Bapst A, Knopfel T, Nolan K, Imeri F, Schuh C, Hall A, et al. Neurogenic and pericytic plasticity of conditionally immortalized cells derived from renal erythropoietin-producing cells. J Cell Physiol. 2022;: pubmed publisher
King P, Wan J, Guo A, Guo S, Jiang Y, Liu M. Regulation of gliomagenesis and stemness through acid sensor ASIC1a. Int J Oncol. 2021;59: pubmed publisher
Witte K, Pfitzenmaier J, Storm J, L xfc tkemeyer M, Wimmer C, Schulten W, et al. Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role of NF-κB RELA. Int J Mol Sci. 2021;22: pubmed publisher
Wamba B, Ghosh P, Mbaveng A, Bhattacharya S, Debarpan M, Depanwita S, et al. Botanical from Piper capense Fruit Can Help to Combat the Melanoma as Demonstrated by In Vitro and In Vivo Studies. Evid Based Complement Alternat Med. 2021;2021:8810368 pubmed publisher
Witte K, Hertel O, Windm xf6 ller B, Helweg L, H xf6 ving A, Knabbe C, et al. Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribosomal Gene Expressions in Various Human Cancer Stem-like Cell Populations. Cancers (Basel). 2021;13: pubmed publisher
Abouelkheir M, Shabaan D, Shahien M. Delayed blockage of prostaglandin EP4 receptors can reduce dedifferentiation, epithelial-to-mesenchymal transition and fibrosis following acute kidney injury. Clin Exp Pharmacol Physiol. 2021;48:791-800 pubmed publisher
Wan J, Guo A, King P, Guo S, Saafir T, Jiang Y, et al. TRPM7 Induces Tumorigenesis and Stemness Through Notch Activation in Glioma. Front Pharmacol. 2020;11:590723 pubmed publisher
Schulte Am Esch J, Windm xf6 ller B, Hanewinkel J, Storm J, F xf6 rster C, Wilkens L, et al. Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition. Cancers (Basel). 2020;12: pubmed publisher
Horiguchi K, Yoshida S, Tsukada T, Nakakura T, Fujiwara K, Hasegawa R, et al. Expression and functions of cluster of differentiation 9 and 81 in rat mammary epithelial cells. J Reprod Dev. 2020;66:515-522 pubmed publisher
Harper S, Hoff M, Skepper J, Davies S, Huguet E. Portal venous repopulation of decellularised rat liver scaffolds with syngeneic bone marrow stem cells. J Tissue Eng Regen Med. 2020;14:1502-1512 pubmed publisher
Shang L, Deng D, Roffel S, Gibbs S. Differential influence of Streptococcus mitis on host response to metals in reconstructed human skin and oral mucosa. Contact Dermatitis. 2020;83:347-360 pubmed publisher
Ma D, Hou L, Xia H, Li H, Fan H, Jia X, et al. PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β‑catenin signaling pathway. Oncol Rep. 2020;44:533-542 pubmed publisher
Liu J, Dong X, Li Z, Wang G, Zhou Y, Liu C, et al. Xiaoyukang Jiaonang Promotes the Degradation of Hypoxia-Inducible Factor 1α and Antiangiogenesis and Anti-Inflammation in Chronic Subdural Hematoma Rat Model. Evid Based Complement Alternat Med. 2020;2020:2305017 pubmed publisher
Kylmä A, Tolvanen T, Carpén T, Haglund C, Mäkitie A, Mattila P, et al. Elevated TLR5 expression in vivo and loss of NF-κΒ activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma. Exp Mol Pathol. 2020;114:104435 pubmed publisher
Qi L, Ahmadi A, Huang J, Chen M, Pan B, Kuwabara H, et al. Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats. Diabetes. 2020;69:699-712 pubmed publisher
Zhao F, Zhou L, Liu J, Xu Z, Ping W, Li H, et al. Construction of a vascularized bladder with autologous adipose-derived stromal vascular fraction cells combined with bladder acellular matrix via tissue engineering. J Tissue Eng. 2019;10:2041731419891256 pubmed publisher
Aghajani Nargesi A, Zhu X, Liu Y, Tang H, Jordan K, Lerman L, et al. Renal Artery Stenosis Alters Gene Expression in Swine Scattered Tubular-Like Cells. Int J Mol Sci. 2019;20: pubmed publisher
Kasurinen A, Hagstrom J, Laitinen A, Kokkola A, Böckelman C, Haglund C. Evaluation of toll-like receptors as prognostic biomarkers in gastric cancer: high tissue TLR5 predicts a better outcome. Sci Rep. 2019;9:12553 pubmed publisher
Nargesi A, Zhu X, Conley S, Woollard J, Saadiq I, Lerman L, et al. Renovascular disease induces mitochondrial damage in swine scattered tubular cells. Am J Physiol Renal Physiol. 2019;317:F1142-F1153 pubmed publisher
Ruuskanen M, Leivo I, Minn H, Vahlberg T, Haglund C, Hagstrom J, et al. Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma. BMC Cancer. 2019;19:624 pubmed publisher
Haeggblom L, Näsman A, Ramqvist T, Haglund C, Hagstrom J, Mäkitie A, et al. TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence. Acta Otolaryngol. 2019;139:206-210 pubmed publisher
Uygur B, Leikina E, Melikov K, Villasmil R, Verma S, Vary C, et al. Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells. Mol Cancer Res. 2019;17:806-820 pubmed publisher
Fu J, Zhou Y, Shi X, Kang Y, Lu Z, Li Y, et al. Spontaneous formation of tumor spheroid on a hydrophilic filter paper for cancer stem cell enrichment. Colloids Surf B Biointerfaces. 2019;174:426-434 pubmed publisher
Bhattacharyya S, Mitra D, Ray S, Biswas N, Banerjee S, Majumder B, et al. Reversing effect of Lupeol on vasculogenic mimicry in murine melanoma progression. Microvasc Res. 2019;121:52-62 pubmed publisher
Yang Z, Zhang C, Qi W, Cui Y, Xuan Y. GLI1 promotes cancer stemness through intracellular signaling pathway PI3K/Akt/NFκB in colorectal adenocarcinoma. Exp Cell Res. 2018;373:145-154 pubmed publisher
Bak D, Choi M, Kim S, Lee B, Kim J, Jeon E, et al. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth. Korean J Physiol Pharmacol. 2018;22:555-566 pubmed publisher
Parte S, Batra S, Kakar S. Characterization of stem cell and cancer stem cell populations in ovary and ovarian tumors. J Ovarian Res. 2018;11:69 pubmed publisher
Kylmä A, Jouhi L, Listyarifah D, Mohamed H, Mäkitie A, Remes S, et al. Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma. Br J Cancer. 2018;119:89-95 pubmed publisher
Li H, Meng Q, Noh H, Somaiah N, Torres K, Xia X, et al. Cell-surface vimentin-positive macrophage-like circulating tumor cells as a novel biomarker of metastatic gastrointestinal stromal tumors. Oncoimmunology. 2018;7:e1420450 pubmed publisher
Kim M, Cho H, Yoon H, Ahn Y, Park E, Jin Y, et al. JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Sci Rep. 2018;8:6611 pubmed publisher
Na B, Hoang T, Kim J. Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-κB Activation in Human Myeloid Leukemia THP-1 Cells. Biomed Res Int. 2018;2018:4319369 pubmed publisher
Xiao Z, Chen X, Pan Q, Yang Q, Li K. Expression of Nestin, CD133 and Sox2 in Meningiomas. Turk Neurosurg. 2018;28:910-914 pubmed publisher
Zou X, Kwon S, Jiang K, Ferguson C, Puranik A, Zhu X, et al. Renal scattered tubular-like cells confer protective effects in the stenotic murine kidney mediated by release of extracellular vesicles. Sci Rep. 2018;8:1263 pubmed publisher
Alhaider I, Mohamed M, Ahmed K, Kumar A. Date Palm (Phoenix dactylifera) Fruits as a Potential Cardioprotective Agent: The Role of Circulating Progenitor Cells. Front Pharmacol. 2017;8:592 pubmed publisher
Larsson O, Tengroth L, Xu Y, Uddman R, Kumlien Georén S, Cardell L. Substance P represents a novel first-line defense mechanism in the nose. J Allergy Clin Immunol. 2018;141:128-136.e3 pubmed publisher
Calle A, Nair N, Oo A, Prieto Vila M, Koga M, Khayrani A, et al. A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm). Am J Cancer Res. 2016;6:2799-2815 pubmed
Helminen O, Huhta H, Leppänen J, Kauppila J, Takala H, Lehenkari P, et al. Nuclear localization of Toll-like receptor 5 in Barrett's esophagus and esophageal adenocarcinoma is associated with metastatic behavior. Virchows Arch. 2016;469:465-70 pubmed publisher
Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Carevic M, Oz H, Fuchs K, Laval J, Schroth C, Frey N, et al. CXCR1 Regulates Pulmonary Anti-Pseudomonas Host Defense. J Innate Immun. 2016;8:362-73 pubmed publisher
Renkonen J, Toppila Salmi S, Joenväärä S, Mattila P, Parviainen V, Hagström J, et al. Expression of Toll-like receptors in nasal epithelium in allergic rhinitis. APMIS. 2015;123:716-25 pubmed publisher
Jouhi L, Datta N, Renkonen S, Atula T, Mäkitie A, Haglund C, et al. Expression of toll-like receptors in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma--an in vivo and in vitro study. Tumour Biol. 2015;36:7755-64 pubmed publisher
Mäkinen L, Atula T, Häyry V, Jouhi L, Datta N, Lehtonen S, et al. Predictive role of Toll-like receptors 2, 4, and 9 in oral tongue squamous cell carcinoma. Oral Oncol. 2015;51:96-102 pubmed publisher
Uchida M, Oyanagi E, Kawanishi N, Iemitsu M, Miyachi M, Kremenik M, et al. Exhaustive exercise increases the TNF-? production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice. Immunol Lett. 2014;158:151-8 pubmed publisher
Helminen O, Huhta H, Takala H, Lehenkari P, Saarnio J, Kauppila J, et al. Increased Toll-like receptor 5 expression indicates esophageal columnar dysplasia. Virchows Arch. 2014;464:11-8 pubmed publisher
Grimm M, Munz A, Exarchou A, Polligkeit J, Reinert S. Immunohistochemical detection of Helicobacter pylori without association of TLR5 expression in oral squamous cell carcinoma. J Oral Pathol Med. 2014;43:35-44 pubmed publisher
Kauppila J, Mattila A, Karttunen T, Salo T. Toll-like receptor 5 (TLR5) expression is a novel predictive marker for recurrence and survival in squamous cell carcinoma of the tongue. Br J Cancer. 2013;108:638-43 pubmed publisher
Harman A, Bye C, Nasr N, Sandgren K, Kim M, Mercier S, et al. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J Immunol. 2013;190:66-79 pubmed publisher
Kato K, Lillehoj E, Park Y, Umehara T, Hoffman N, Madesh M, et al. Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88. J Immunol. 2012;188:2014-22 pubmed publisher
Smith N, Varley C, Eardley I, Feather S, Trejdosiewicz L, Southgate J. Toll-like receptor responses of normal human urothelial cells to bacterial flagellin and lipopolysaccharide. J Urol. 2011;186:1084-92 pubmed publisher
Faham A, Altin J. Antigen-containing liposomes engrafted with flagellin-related peptides are effective vaccines that can induce potent antitumor immunity and immunotherapeutic effect. J Immunol. 2010;185:1744-54 pubmed publisher
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
Deng J, Ma Krupa W, Gewirtz A, Younge B, Goronzy J, Weyand C. Toll-like receptors 4 and 5 induce distinct types of vasculitis. Circ Res. 2009;104:488-95 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Fukata M, Breglio K, Chen A, Vamadevan A, Goo T, Hsu D, et al. The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease. J Immunol. 2008;180:1886-94 pubmed
Ha H, Lee J, Kim H, Kwak H, Kim H, Lee S, et al. Stimulation by TLR5 modulates osteoclast differentiation through STAT1/IFN-beta. J Immunol. 2008;180:1382-9 pubmed
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Crellin N, Garcia R, Hadisfar O, Allan S, Steiner T, Levings M. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol. 2005;175:8051-9 pubmed
Miller L, Sørensen O, Liu P, Jalian H, Eshtiaghpour D, Behmanesh B, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005;174:6137-43 pubmed
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product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-16518
SKU :
NB120-16518
product name :
CD133 Antibody - BSA Free
description :
The CD133 Antibody - BSA Free from Novus Biologicals is a rabbit polyclonal antibody to CD133. This antibody reacts with human,mouse,porcine,rat. The CD133 Antibody - BSA Free has been validated for the following applications: Chromatin Immunoprecipitation (ChIP),IF/IHC,Flow Cytometry,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Block/Neutralize,Immunocytochemistry/ Immunofluorescence.
target :
CD133
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide corresponding to a C-terminal region of CD133 (within amino acids 750-865).
isotype :
IgG
marker :
Stem Cell Marker
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Rat
specificity :
CD133 - Hematopoietic Stem Cell Marker
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
gene symbol :
PROM1
applications :
Chromatin Immunoprecipitation (ChIP),IF/IHC,Flow Cytometry,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Block/Neutralize,Immunocytochemistry/ Immunofluorescence
USD :
469
USD 2025 :
469 USD
alt names :
AC133 Stargardt disease 4 (autosomal dominant), CD133, CD133 retinal 2, prominin (mouse)-like 1, prominin 1
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.