Serotonin Antibody (5HT-H209) - Unpurified | Novus Biologicals NB120-16007 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Serotonin Antibody (5HT-H209) - Unpurified

catalog :

NB120-16007

quantity :

0.05 ml

price :

99 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5HT-H209

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 10

Reference
Wang Y, Sims C, Allbritton N. Enterochromaffin Cell-Enriched Monolayer Platform for Assaying Serotonin Release from Human Primary Intestinal Cells. Anal Chem. 2020;92:12330-12337 pubmed publisher
Sugisawa E, Takayama Y, Takemura N, Kondo T, Hatakeyama S, Kumagai Y, et al. RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis. Cell. 2020;: pubmed publisher
Negi S, BOLT C, Zhang H, Stubbs L. An extended regulatory landscape drives Tbx18 activity in a variety of prostate-associated cell lineages. Dev Biol. 2019;446:180-192 pubmed publisher
Jung K, Miyazaki A, Hu H, Saif L. Susceptibility of porcine IPEC-J2 intestinal epithelial cells to infection with porcine deltacoronavirus (PDCoV) and serum cytokine responses of gnotobiotic pigs to acute infection with IPEC-J2 cell culture-passaged PDCoV. Vet Microbiol. 2018;221:49-58 pubmed publisher
Jung K, Miyazaki A, Saif L. Immunohistochemical detection of the vomiting-inducing monoamine neurotransmitter serotonin and enterochromaffin cells in the intestines of conventional or gnotobiotic (Gn) pigs infected with porcine epidemic diarrhea virus (PEDV) and serum cytokine . Res Vet Sci. 2018;119:99-108 pubmed publisher
Gwynne W, Hallett R, Girgis Gabardo A, Bojovic B, Dvorkin Gheva A, Aarts C, et al. Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts. Oncotarget. 2017;8:32101-32116 pubmed publisher
Hallett R, Girgis Gabardo A, Gwynne W, Giacomelli A, Bisson J, Jensen J, et al. Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer. Oncotarget. 2016;7:53137-53152 pubmed publisher
Delgermurun D, Yamaguchi S, Ichii O, Kon Y, Ito S, Otsuguro K. Hydrogen sulfide activates TRPA1 and releases 5-HT from epithelioid cells of the chicken thoracic aorta. Comp Biochem Physiol C Toxicol Pharmacol. 2016;187:43-9 pubmed publisher
Kluger N, Jokinen M, Lintulahti A, Krohn K, Ranki A. Gastrointestinal immunity against tryptophan hydroxylase-1, aromatic L-amino-acid decarboxylase, AIE-75, villin and Paneth cells in APECED. Clin Immunol. 2015;158:212-20 pubmed publisher
Talchai C, Xuan S, Kitamura T, Depinho R, Accili D. Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nat Genet. 2012;44:406-12, S1 pubmed publisher

product information

brand :

Novus

master code :

NB120-16007

SKU :

NB120-16007-0.05ml

product name :

Serotonin Antibody (5HT-H209) - Unpurified

description :

The Serotonin Antibody (5HT-H209) - Unpurified from Novus Biologicals is a mouse monoclonal antibody to Serotonin. This antibody reacts with human, mouse, porcine, chicken, rhesus macaque. The Serotonin Antibody (5HT-H209) - Unpurified has been validated for the following applications: Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

target :

Serotonin

category :

Primary Antibodies

unit size :

0.05 ml

buffer :

Cell culture supernatant dialysed against 0.05 mol/L Tris/HCl (pH 7.2)

clonality :

Monoclonal

clone :

5HT-H209

conjugate :

Unconjugated

host :

Mouse

immunogen :

5-Hydroxytryptamine hydrochloride (3-(2-aminoethyl)-5-hydroxyindole;serotonin).

isotype :

IgG1 Kappa

purity :

Tissue culture supernatant

species :

Human, Mouse, Porcine, Chicken, Rhesus Macaque

specificity :

Reacts with serotonin in a broad range of normal, hyperplastic and neoplastic tissues. Serotonin is also called 5-hydroxytryptamine. The antibody is of particular importance in identifying primary and metastatic carcinoid tumors expressing serotonin. NB120-16007 may be a useful tool for characterization of carcinoids. In a study of 48 cases of adenomas and carcinoid tumours of the middle ear, the labelled tumour cells in 12 cases (25%).

catalog number base :

NB120-16007

applications :

Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

2020 USD :

2021 USD :

99 USD

storage :

Store at 4C. Do not freeze.