product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rab5a Antibody
catalog :
NB120-13253
quantity :
0.1 mg (also 0.025 mg)
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 15
Reference
Choi G, Park J, Park M, Yoon J, Han H. Glucocorticoid enhances presenilin1-dependent Aβ production at ER's mitochondrial-associated membrane by downregulating Rer1 in neuronal cells. Redox Biol. 2023;65:102821 pubmed publisher
Chae C, Yoon J, Lim J, Park J, Cho J, Jung Y, et al. TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ. Autophagy. 2023;19:2752-2768 pubmed publisher
Chae C, Choi G, Jung Y, Lim J, Cho J, Yoon J, et al. High glucose-mediated VPS26a down-regulation dysregulates neuronal amyloid precursor protein processing and tau phosphorylation. Br J Pharmacol. 2022;179:3934-3950 pubmed publisher
Chae C, Lee H, Choi G, Jung Y, Kim J, Lim J, et al. High glucose-mediated PICALM and mTORC1 modulate processing of amyloid precursor protein via endosomal abnormalities. Br J Pharmacol. 2020;177:3828-3847 pubmed publisher
Rostami J, Fotaki G, Sirois J, Mzezewa R, Bergström J, Essand M, et al. Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain. J Neuroinflammation. 2020;17:119 pubmed publisher
Fred S, Laukkanen L, Brunello C, Vesa L, Göös H, Cardon I, et al. Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2. J Biol Chem. 2019;294:18150-18161 pubmed publisher
Rocha E, De Miranda B, Castro S, Drolet R, Hatcher N, Yao L, et al. LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease. Neurobiol Dis. 2020;134:104626 pubmed publisher
Weng Q, Wang J, Wang J, He D, Cheng Z, Zhang F, et al. Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Cell Stem Cell. 2019;24:707-723.e8 pubmed publisher
Pang J, Peng H, Wang S, Xu X, Xu F, Wang Q, et al. Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1627-1641 pubmed publisher
Cabrera Pastor A, Arenas Y, Taoro Gonzalez L, Montoliu C, Felipo V. Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP. Neuropharmacology. 2019;: pubmed publisher
Di Pietro C, La Sala G, Matteoni R, Marazziti D, Tocchini Valentini G. Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1+/- mouse models of medulloblastoma. Exp Neurol. 2019;312:33-42 pubmed publisher
Yang X, Ren H, Wood K, Li M, Qiu S, Shi F, et al. Depletion of microglia augments the dopaminergic neurotoxicity of MPTP. FASEB J. 2018;32:3336-3345 pubmed publisher
Reyes Aguirre L, Lamas M. Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury. Front Neurosci. 2016;10:523 pubmed
Pinner A, Tucholski J, Haroutunian V, McCullumsmith R, Meador Woodruff J. Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia. Schizophr Res. 2016;177:78-87 pubmed publisher
Arnold J, Salvatore M. Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats. ACS Chem Neurosci. 2016;7:227-39 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NB120-13253
SKU :
NB120-13253
product name :
Rab5a Antibody
description :
The Rab5a Antibody from Novus Biologicals is a rabbit polyclonal antibody to Rab5a. This antibody reacts with bovine,human,monkey,mouse,rat. The Rab5a Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Western Blot,Functional,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence.
target :
Rab5a
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS, 50% Glycerol
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Human Rab5 synthetic peptide conjugated to KLH; identical to dog Rab5 sequence over the residues
isotype :
IgG
marker :
Early Endosome Marker
purity :
Protein A purified
species :
Bovine,Human,Monkey,Mouse,Rat
specificity :
Detects approx 26kDa
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
gene symbol :
RAB5A
accessionNumbers :
Q6FI44
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Western Blot,Functional,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
459 USD
alt names :
RAB5A, member RAS oncogene family, RAB5RAS-associated protein RAB5A, ras-related protein Rab-5A
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.