product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CaMKII alpha/beta [p Thr286, p Thr287] Antibody (22B1) - BSA Free
catalog :
NB110-96869
quantity :
0.1 mg (also 0.025 mg)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
22B1
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 11
Reference
LaMoia T, Hubbard B, Guerra M, Nasiri A, Sakuma I, Kahn M, et al. Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation. Cell Metab. 2024;36:2329-2340.e4 pubmed publisher
Ghane M, Wei W, Yakout D, Allen Z, Miller C, Dong B, et al. Arc ubiquitination regulates endoplasmic reticulum-mediated Ca2+ release and CaMKII signaling. Front Cell Neurosci. 2023;17:1091324 pubmed publisher
Lee Y, Kang J, Ham O, Son M, Lee M. Gut metabolite trimethylamine N-oxide induces aging-associated phenotype of midbrain organoids for the induced pluripotent stem cell-based modeling of late-onset disease. Front Aging Neurosci. 2022;14:925227 pubmed publisher
Howard S, Ceppi I, Anand R, Geiger R, Cejka P. The internal region of CtIP negatively regulates DNA end resection. Nucleic Acids Res. 2020;48:5485-5498 pubmed publisher
Cai B, Kasikara C, Doran A, Ramakrishnan R, Birge R, Tabas I. MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Sci Signal. 2018;11: pubmed publisher
Ersoy B, Maner Smith K, Li Y, Alpertunga I, Cohen D. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. J Clin Invest. 2018;128:141-156 pubmed publisher
Ritter A, Friemel A, Kreis N, Louwen F, Yuan J. Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells. Oncotarget. 2016;7:84271-84285 pubmed publisher
Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
Sears C, Cooney S, Chin Sinex H, Mendonca M, Turchi J. DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer. DNA Repair (Amst). 2016;40:35-46 pubmed publisher
Yi Y, Park J, Kwak S, Seong Y. Co-treatment with BEZ235 Enhances Sensitivity of BRCA1-negative Breast Cancer Cells to Olaparib. Anticancer Res. 2015;35:3829-38 pubmed
Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, et al. Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/?-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria. J Biol Chem. 2013;288:23368-79 pubmed publisher
product information
master code :
NB110-96869
SKU :
NB110-96869
product name :
CaMKII alpha/beta [p Thr286, p Thr287] Antibody (22B1) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The CaMKII alpha/beta [p Thr286, p Thr287] Antibody (22B1) - BSA Free from Novus is a mouse monoclonal antibody to CaMKII alpha/beta. This antibody reacts with human,mouse,rat. The CaMKII alpha/beta [p Thr286, p Thr287] Antibody (22B1) - BSA Free has been validated for the following applications: Western Blot,Immunoblotting,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
CaMKII alpha/beta
category :
Primary Antibodies
buffer :
PBS (pH 7.4), 50% Glycerol
clonality :
Monoclonal
clone :
22B1
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Synthetic peptide
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
specificity :
This antibody is specific for a and B subunits of CaMKII only when they are phosphorylated at Thr-286/287 (in B)
gene symbol :
CAMK2A
accessionNumbers :
P11275
applications :
Western Blot,Immunoblotting,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase II alpha-B subunit, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CAMKAcalcium/calmodulin-dependent protein kinase type II subunit alpha, CaMK-II alpha subunit, CaMK-II subunit alpha, CaMKIINalpha, CaM-kinase II alpha chain, EC 2.7.11, EC 2.7.11.17, KIAA0968calcium/calmodulin-dependent protein kinase type II alpha chain
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.