product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LRP2 Antibody (CD7D5) - Azide and BSA Free
catalog :
NB110-96417
quantity :
0.1 mg
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CD7D5
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3E
Pósfai E, Petropoulos S, de Barros F, Schell J, Jurisica I, Sandberg R, et al. Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo. elife. 2017;6: pubmed publisher
Gujarati N, Frimpong B, Zaidi M, Bronstein R, Revelo M, Haley J, et al. Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease. Nat Commun. 2024;15:8038 pubmed publisher
LIAN E, Pietrobon A, Stanford W. Differentiation and single-cell RNA-seq analyses of human pluripotent-stem-cell-derived renal organoids. STAR Protoc. 2023;4:102314 pubmed publisher
Polesel M, Kaminska M, Haenni D, Bugarski M, Schuh C, Jankovic N, et al. Spatiotemporal organisation of protein processing in the kidney. Nat Commun. 2022;13:5732 pubmed publisher
Pietrobon A, Yockell Lelièvre J, Flood T, Stanford W. Renal organoid modeling of tuberous sclerosis complex reveals lesion features arise from diverse developmental processes. Cell Rep. 2022;40:111048 pubmed publisher
Sander V, Przepiorski A, Crunk A, Hukriede N, Holm T, Davidson A. Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells. STAR Protoc. 2020;1:100150 pubmed publisher
Lin Y, Lin Y, Nhieu J, Zhang X, Wei L. Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases. Int J Mol Sci. 2020;21: pubmed publisher
Seo J, Kang M, Yang W, Hwang W, Kim S, Hong S, et al. Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity. Nat Commun. 2020;11:2024 pubmed publisher
Chen P, Qin L, Li G, Malagon Lopez J, Wang Z, Bergaya S, et al. Smooth Muscle Cell Reprogramming in Aortic Aneurysms. Cell Stem Cell. 2020;26:542-557.e11 pubmed publisher
Suzuki C, Tanida I, Oliva Trejo J, Kakuta S, Uchiyama Y. Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions. Int J Mol Sci. 2019;21: pubmed publisher
Petty A, Li A, Wang X, Dai R, Heyman B, Hsu D, et al. Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment. J Clin Invest. 2019;129:5151-5162 pubmed publisher
Fels J, Scharner B, Zarbock R, Zavala Guevara I, Lee W, Barbier O, et al. Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule. Int J Mol Sci. 2019;20: pubmed publisher
Kinguchi S, Wakui H, Azushima K, Haruhara K, Koguchi T, Ohki K, et al. Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension. J Am Heart Assoc. 2019;8:e012395 pubmed publisher
Mazzone A, Gibbons S, Eisenman S, Strege P, Zheng T, D Amato M, et al. Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins. FASEB J. 2019;33:6632-6642 pubmed publisher
Mohr J, Voggel J, Vohlen C, Dinger K, Dafinger C, Fink G, et al. IL-6/Smad2 signaling mediates acute kidney injury and regeneration in a murine model of neonatal hyperoxia. FASEB J. 2019;33:5887-5902 pubmed publisher
Schuh C, Polesel M, Platonova E, Haenni D, Gassama A, Tokonami N, et al. Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis. J Am Soc Nephrol. 2018;29:2696-2712 pubmed publisher
Przepiorski A, Sander V, TRAN T, Hollywood J, Sorrenson B, Shih J, et al. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. 2018;11:470-484 pubmed publisher
Wang K, Chen D, Qian Z, Cui D, Gao L, Lou M. Hedgehog/Gli1 signaling pathway regulates MGMT expression and chemoresistance to temozolomide in human glioblastoma. Cancer Cell Int. 2017;17:117 pubmed publisher
Tanno B, Leonardi S, Babini G, Giardullo P, De Stefano I, Pasquali E, et al. Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1 +/- granule cell precursors after radiation injury. Sci Rep. 2017;7:14238 pubmed publisher
Wei R, Lv M, Li F, Cheng T, Zhang Z, Jiang G, et al. Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis. Oncotarget. 2017;8:67315-67328 pubmed publisher
Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed publisher
Xu T, Zhang H, Park S, Venneti S, Kuick R, Ha K, et al. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia. 2017;19:216-225 pubmed publisher
Puri P, Bushnell D, Schaefer C, Bates C. Six2creFrs2? knockout mice are a novel model of renal cystogenesis. Sci Rep. 2016;6:36736 pubmed publisher
Wu M, Ingram L, Tolosa E, Vera R, Li Q, Kim S, et al. Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis. J Biol Chem. 2016;291:25749-25760 pubmed
Viall C, Chen Q, Stone P, Chamley L. Human extravillous trophoblasts bind but do not internalize antiphospholipid antibodies. Placenta. 2016;42:9-16 pubmed publisher
Vidal M, Lourenço S, Soares F, Gurgel C, Studart E, Valverde L, et al. The sonic hedgehog signaling pathway contributes to the development of salivary gland neoplasms regardless of perineural infiltration. Tumour Biol. 2016;37:9587-601 pubmed publisher
Valverde L, Pereira T, Dias R, Guimarães V, Ramos E, Santos J, et al. Macrophages and endothelial cells orchestrate tumor-associated angiogenesis in oral cancer via hedgehog pathway activation. Tumour Biol. 2016;37:9233-41 pubmed publisher
Comba A, Almada L, Tolosa E, Iguchi E, Marks D, Vara Messler M, et al. Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid. J Biol Chem. 2016;291:1933-47 pubmed publisher
Yeddula N, Xia Y, Ke E, Beumer J, Verma I. Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma. Proc Natl Acad Sci U S A. 2015;112:E6476-85 pubmed publisher
Kawano H, Ito Y, Kanai F, Nakamura E, Tada N, Takai S, et al. Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway. Oncol Rep. 2015;34:2251-8 pubmed publisher
Jackson D, Smith T, Amarsaikhan N, Han W, Neil M, Boi S, et al. Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells. J Immunol. 2015;195:2908-16 pubmed publisher
Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, et al. Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension. Kidney Int. 2014;86:570-81 pubmed publisher
Tsuchida Y, Kaneko Y, Otsuka T, Goto K, Saito A, Yamamoto K, et al. Upregulation of prolactin receptor in proximal tubular cells was induced in cardiac dysfunction model mice. Clin Exp Nephrol. 2014;18:65-74 pubmed publisher
Nashida T, Sato R, Haga Tsujimura M, Yoshie S, Yoshimura K, Imai A, et al. Antigen-presenting cells in parotid glands contain cystatin D originating from acinar cells. Arch Biochem Biophys. 2013;530:32-9 pubmed publisher
Chang A, Ohse T, Krofft R, Wu J, Eddy A, Pippin J, et al. Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2. Nephrol Dial Transplant. 2012;27:1330-43 pubmed publisher
product information
master code :
NB110-96417
SKU :
NB110-96417
product name :
LRP2 Antibody (CD7D5) - Azide and BSA Free
unit size :
0.1 mg
description :
The LRP2 Antibody (CD7D5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to LRP2. This antibody reacts with human,mouse,rat. The LRP2 Antibody (CD7D5) - Azide and BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunohistochemistry Whole-Mount,Immunocytochemistry/ Immunofluorescence.
target :
LRP2
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
CD7D5
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Purified human LRP2.
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
theoretical molecular weight :
600 kDa
gene symbol :
LRP2
accessionNumbers :
P98164
applications :
IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunohistochemistry Whole-Mount,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
449 USD
alt names :
calcium sensor protein, DBSlow-density lipoprotein receptor-related protein 2, EC 1.1.2.3, EC 3.4.21.9, Glycoprotein 330, GP330, Heymann nephritis antigen homolog, low density lipoprotein receptor-related protein 2, LRP-2, megalin
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.